Equilibrium function in the cerebellum （vestibulo-cerebellar system） can deteriorate under the influence of alcohol. In the Romberg posture, the center of gravity, which was measured every 50 ms by stabilometry, app...Equilibrium function in the cerebellum （vestibulo-cerebellar system） can deteriorate under the influence of alcohol. In the Romberg posture, the center of gravity, which was measured every 50 ms by stabilometry, appeared to shift with alcohol ingestion. In the previous study, a locus in the center of gravity （stabilogram） was converted to values of statistical indices such as area of sway, total locus length, sparse density, and locus length per unit area, although these indices could not always distinguish between the stabilograms sampled from seven healthy young males in sober and intoxicated states. This measurement was made with an AMTI force plate. In this study, ＂translation error＂ was estimated in a d-dimensional embedding space in order to compare stabilograms recorded before and after the ingestion of doubly diluted brandy in 30 s （1 ≤ d ≤ 10）. The authors succeeded in validating stochastic differential equations as a mathematical model of the body sway. Although the postural control system shows different patterns in the lateral and anterior-posterior directions, the randomness in the model was preserved after alcohol intake and significantly increased in the medial/lateral direction. Visual information referred by the postural conlrol system when standing might be interfered by the effects of intoxication, which was regarded as disturbance. The possibility of detecting alcohol-ingestion-induced reduction of the equilibrium function and its recovery process are also suggested in this paper. This method is considered to be useful to diagnose the disorders of the vestibulo-cerebellar system.展开更多
We propose a method which uses functional singular component to establish functional additive models. The proposed methodology reduces the curve regression problem to ordinary(i.e., scalar) additive regression problem...We propose a method which uses functional singular component to establish functional additive models. The proposed methodology reduces the curve regression problem to ordinary(i.e., scalar) additive regression problems of the singular components of the predictor process and response process. Consistency of estimators for the nonparametric function and prediction are proved, respectively. A simulation study is conducted to investigate the finite sample performances of the proposed estimators.展开更多
文摘Equilibrium function in the cerebellum （vestibulo-cerebellar system） can deteriorate under the influence of alcohol. In the Romberg posture, the center of gravity, which was measured every 50 ms by stabilometry, appeared to shift with alcohol ingestion. In the previous study, a locus in the center of gravity （stabilogram） was converted to values of statistical indices such as area of sway, total locus length, sparse density, and locus length per unit area, although these indices could not always distinguish between the stabilograms sampled from seven healthy young males in sober and intoxicated states. This measurement was made with an AMTI force plate. In this study, ＂translation error＂ was estimated in a d-dimensional embedding space in order to compare stabilograms recorded before and after the ingestion of doubly diluted brandy in 30 s （1 ≤ d ≤ 10）. The authors succeeded in validating stochastic differential equations as a mathematical model of the body sway. Although the postural control system shows different patterns in the lateral and anterior-posterior directions, the randomness in the model was preserved after alcohol intake and significantly increased in the medial/lateral direction. Visual information referred by the postural conlrol system when standing might be interfered by the effects of intoxication, which was regarded as disturbance. The possibility of detecting alcohol-ingestion-induced reduction of the equilibrium function and its recovery process are also suggested in this paper. This method is considered to be useful to diagnose the disorders of the vestibulo-cerebellar system.
基金supported by National Natural Science Foundation of China (Grant Nos. 11171331, 11561006, 11331011)Program for Creative Research Group of National Natural Science Foundation of China (Grant No. 61621003)+4 种基金a Grant from the Key Lab of Random Complex Structure and Data Science, Chinese Academy of Sciencesthe Natural Science Foundation of Shenzhen UniversityResearch Projects of Colleges and Universities in Guangxi (Grant No. KY2015YB171)Innovation Project of Guangxi Graduate Education (Grant No. JGY2015122)a Grant from the Key Base of Humanities and Social Sciences in Guangxi College
文摘We propose a method which uses functional singular component to establish functional additive models. The proposed methodology reduces the curve regression problem to ordinary(i.e., scalar) additive regression problems of the singular components of the predictor process and response process. Consistency of estimators for the nonparametric function and prediction are proved, respectively. A simulation study is conducted to investigate the finite sample performances of the proposed estimators.
