[Objective] The research aimed to understand the high and efficiency technique in intersubspecific hybrid rice Yongyou No.9.[Method] We conducted the correlation analysis,regression analysis and path analysis of inter...[Objective] The research aimed to understand the high and efficiency technique in intersubspecific hybrid rice Yongyou No.9.[Method] We conducted the correlation analysis,regression analysis and path analysis of intersubspecific hybrid rice Yongyou No.9 based on the data of its ear,grain and weight at different yield levels.[Result]The performance of ear,grain and weight in Yongyou No.9 showed significant difference among different yield levels.The enhancement of effective ears would restrain the number of per ear total grains.It was found that the direct contributions of main economic traits to yield were determined to be per ear total grainseffective earseed setting rate1 000-grain weight.[Conclusion]The high-yield and effective cultivation techniques were suggested as follows：on the basis of certain effective ear number,grain number per ear should be mainly focused with a consideration to 1 000-grain weight.展开更多
The proposed scheme is based on Discrete Fourier Transform (DFT) domain processing. The key technology of this scheme is jamming parameters' accurate estimation and jamming reconstruction. Compared with the 't...The proposed scheme is based on Discrete Fourier Transform (DFT) domain processing. The key technology of this scheme is jamming parameters' accurate estimation and jamming reconstruction. Compared with the 'threshold exciser' scheme the proposed scheme can eliminate more jamming energy on the whole frequency band with the minimum loss of useful signal energy. As shown in the research and simulation, the proposed scheme is much better than the 'threshold exciser' scheme, especially in the case of high power jamming whereas the 'threshold exciser' scheme might be invalid.展开更多
[Objective] The paper was focused on the way how to increase the yield of hybrid rice Zhongzheyou No.8. [Method] The relationship among yield-related traits and their contribution to yield were investigated through co...[Objective] The paper was focused on the way how to increase the yield of hybrid rice Zhongzheyou No.8. [Method] The relationship among yield-related traits and their contribution to yield were investigated through correlation analysis, regression analysis and path analysis. [Result] The performance of ear, grain and weight in Zhongzheyou No.8 showed significant difference among yield levels. The enhancement of effective ears would restrain the number of total grains per ear. It was found that the direct contributions of main economic traits to yield were： number of fil ed grains per ear 〉 number of effective ears 〉1 000-grain weight 〉number of total grains per ear. [Conclusion] The promotion of high-yielding techniques was suggested as fol ows： on the basis of certain number of effective ears, number of fil ed grains per ear should be mainly focused with a consideration to grain weight.展开更多
In order to reduce the hidden danger of noise which can be charactered by singularity spectrum, a new algorithm based on wavelet transform modulus maxima method was proposed. Singularity analysis is one of the most pr...In order to reduce the hidden danger of noise which can be charactered by singularity spectrum, a new algorithm based on wavelet transform modulus maxima method was proposed. Singularity analysis is one of the most promising new approaches for extracting noise hidden information from noisy time series . Because of singularity strength is hard to calculate accurately, a wavelet transform modulus maxima method was used to get singularity spectrum. The singularity spectrum of white noise and aluminium interconnection electromigration noise was calculated and analyzed. The experimental results show that the new algorithm is more accurate than tradition estimating algorithm. The proposed method is feasible and efficient.展开更多
Effect of row space and planting density on yield of Miandan No.12 was studied. The test included four row spaces and two planting densities. Specifically, four row spaces were 50, 67, 83 and 100 cm and two planting d...Effect of row space and planting density on yield of Miandan No.12 was studied. The test included four row spaces and two planting densities. Specifically, four row spaces were 50, 67, 83 and 100 cm and two planting densities were 42 000 and 48 000 plant/hm2. The results showed that Miandan No.12 reached the highest yield when row space was 50 cm and planting density was 48 000 plantJhm2 and Miandan No.12 got the lowest yield when row space was 100 cm and planting density was 42 000 plants/hm2.展开更多
Interleukin-2 （IL）-2 signaling plays a pivotal role in the activation of immune responses, and drugs that block this pathway have been shown to be effective for the immunosuppression in patients with organ transplan...Interleukin-2 （IL）-2 signaling plays a pivotal role in the activation of immune responses, and drugs that block this pathway have been shown to be effective for the immunosuppression in patients with organ transplantation to alleviate/eliminate allograft rejection. The first humanized monoclonal antibody （mAb） daclizumab falls into this category and shows high specificity and affinity against a key component of the IL-2 receptor complex, namely IL-2Ra. To reveal the molecular mechanism of the inhibition of the IL-2 signaling pathway by dacllzumab, we determined the crystal structures of the daclizumab Fab in free form and in complex with the IL-2Ra ectodomain at 2.6 and 2.8 A resolution, respectively. The daclizumab Fab adopts a similar conformation in the presence or absence of the IL- 2Ra ectodomain. The antigen-binding site of daclizumab is mainly composed of live complementarity determining regions （CDRs） that form a large positively charged surface depression and two flanking patches that are generally hydrophobic. The conformational epitope consists of several discontinuous segments of the IL-2Ru ectodomain, a large portion of which overlaps with the regions that interact with IL-2, suggesting that the binding of daclizumab to IL-2Ra would prevent the IL-2 binding to IL-2Ra and the subsequent formation of the IL-2fIL-2Ra[~/c complex, and therefore block the IL-2 signaling pathway. These results also have implications for the design and development of improved mAb drugs targeting IL-2Ra.展开更多
The single ion channel signal is an ionic current that can be recorded by the patch clamp technique. Hidden Markov model (HMM) algorithm has been used to convert the low signal noise ratio (SNR) noisy recording into a...The single ion channel signal is an ionic current that can be recorded by the patch clamp technique. Hidden Markov model (HMM) algorithm has been used to convert the low signal noise ratio (SNR) noisy recording into an idealized quantal one in the case of white background noise. The traditional HMM algorithm is extended and adapted to the colored background noise. A new algorithm called EHMM (Extended HMM) algorithm is proposed, and mainly validated by simulation. Results show that it’s effective.展开更多
A brain-computer interface(BCI)-based electric wheelchair control system was developed, which enables the users to move the wheelchair forward or backward, and turn left or right without any pre-learning. This control...A brain-computer interface(BCI)-based electric wheelchair control system was developed, which enables the users to move the wheelchair forward or backward, and turn left or right without any pre-learning. This control system makes use of the amplitude enhancement of alpha-wave blocking in electroencephalogram(EEG) when eyes close for more than 1 s to constitute a BCI for the switch control of wheelchair movements. The system was formed by BCI control panel, data acquisition, signal processing unit and interface control circuit. Eight volunteers participated in the wheelchair control experiments according to the preset routes. The experimental results show that the mean success control rate of all the subjects was 81.3%, with the highest reaching 93.7%. When one subject's triggering time was 2.8 s, i.e., the flashing time of each cycle light was 2.8 s, the average information transfer rate was 8.10 bit/min, with the highest reaching 12.54 bit/min.展开更多
The high-accuracy, wide-range frequency estimation algorithm for multi-component signals presented in this paper, is based on a numerical differentiation and central Lagrange interpolation. With the sample sequences, ...The high-accuracy, wide-range frequency estimation algorithm for multi-component signals presented in this paper, is based on a numerical differentiation and central Lagrange interpolation. With the sample sequences, which need at most 7 points and are sampled at a sample frequency of 25600 Hz, and computation sequences, using employed a formulation proposed in this paper, the frequencies of each component of the signal are all estimated at an accuracy of 0.001% over 1 Hz to 800 kHz with the amplitudes of each component of the signal varying from 1 V to 200 V and the phase angle of each component of the signal varying from 0° to 360°. The proposed algorithm needs at most a half cycle for the frequencies of each component of the signal under noisy or non-noisy conditions. A testing example is given to illustrate the proposed algorithm in Matlab environment.展开更多
On the basis of calculating the steady-state mean normalized intensity fluctuation of a signal-mode laser system driven by both colored pump noise with signal modulation and the quantum noise with cross-correlation be...On the basis of calculating the steady-state mean normalized intensity fluctuation of a signal-mode laser system driven by both colored pump noise with signal modulation and the quantum noise with cross-correlation between its real and imaginary parts, we analyze the influence of modulation signal, noise, and its correlation form on the statistical fluctuation of the laser system. We have found that when the amplitude of modulation signal weakens and its frequency quickens, the statistical fluctuation will reduce rapidly. The by reducing the intensity of pump noise and quantum noise. statistical fluctuation of the laser system can be restrained Moreover, with prolonging of colored cross-correlation time, the statistical fluctuation of laser system experiences a repeated changing process, that is, from decreasing to augmenting, then to decreasing, and finally to augmenting again. With the decreasing of the value of cross-correlation coe~cient, the statistical fluctuation will decrease too. When the cross-correlation form between the real part and imaginary part of quantum noise is zero correlation, the statistical fluctuation of laser system has a minimum. Compared with the influence of intensity of pump noise, the influence of intensity of quantum noise on the statistical fluctuation is smaller.展开更多
AIM: To systematically investigate if cGMP/cGMP- dependent protein kinase G (PKG) signaling pathway may participate in dendroaspis natriuretic peptide (DNP)-induced relaxation of gastric circular smooth muscle. METHOD...AIM: To systematically investigate if cGMP/cGMP- dependent protein kinase G (PKG) signaling pathway may participate in dendroaspis natriuretic peptide (DNP)-induced relaxation of gastric circular smooth muscle. METHODS: The content of cGMP in guinea pig gastric antral smooth muscle tissue and perfusion solution were measured using radioimmunoassay; spontaneous contraction of gastric antral circular muscles recorded using a 4-channel physiograph; and Ca2+-activated K+ currents (IK(Ca)) and spontaneous transient outward currents (STOCs) in isolated gastric antral myocytes were recorded using the whole-cell patch clamp technique. RESULTS: DNP markedly enhanced cGMP levels in gastric antral smooth muscle tissue and in the perfusion medium. DNP induced relaxation in gastricantral circular smooth muscle, which was inhibited by KT5823, a cGMP-dependent PKG inhibitor. DNP increased IK(Ca). This effect was almost completely blocked by KT5823, and partially blocked by LY83583, an inhibitor of guanylate cyclase to change the production of cGMP. DNP also increased STOCs. The effect of DNP on STOCs was abolished in the presence of KT5823, but not affected by KT-5720, a PKA-specific inhibitor. CONCLUSION: DNP activates IK(Ca) and relaxes guinea-pig gastric antral circular smooth muscle via the cGMP/PKG-dependent singling axis instead of cAMP/ PKA pathway.展开更多
基金Supported by Science Program Foundation of Taizhou(091KY01)~~
文摘[Objective] The research aimed to understand the high and efficiency technique in intersubspecific hybrid rice Yongyou No.9.[Method] We conducted the correlation analysis,regression analysis and path analysis of intersubspecific hybrid rice Yongyou No.9 based on the data of its ear,grain and weight at different yield levels.[Result]The performance of ear,grain and weight in Yongyou No.9 showed significant difference among different yield levels.The enhancement of effective ears would restrain the number of per ear total grains.It was found that the direct contributions of main economic traits to yield were determined to be per ear total grainseffective earseed setting rate1 000-grain weight.[Conclusion]The high-yield and effective cultivation techniques were suggested as follows：on the basis of certain effective ear number,grain number per ear should be mainly focused with a consideration to 1 000-grain weight.
基金the National Natural Science Foundation of China(No.60172029)
文摘The proposed scheme is based on Discrete Fourier Transform (DFT) domain processing. The key technology of this scheme is jamming parameters' accurate estimation and jamming reconstruction. Compared with the 'threshold exciser' scheme the proposed scheme can eliminate more jamming energy on the whole frequency band with the minimum loss of useful signal energy. As shown in the research and simulation, the proposed scheme is much better than the 'threshold exciser' scheme, especially in the case of high power jamming whereas the 'threshold exciser' scheme might be invalid.
基金Supported by Science and Technology Project of Taizhou City(121KY15)~~
文摘[Objective] The paper was focused on the way how to increase the yield of hybrid rice Zhongzheyou No.8. [Method] The relationship among yield-related traits and their contribution to yield were investigated through correlation analysis, regression analysis and path analysis. [Result] The performance of ear, grain and weight in Zhongzheyou No.8 showed significant difference among yield levels. The enhancement of effective ears would restrain the number of total grains per ear. It was found that the direct contributions of main economic traits to yield were： number of fil ed grains per ear 〉 number of effective ears 〉1 000-grain weight 〉number of total grains per ear. [Conclusion] The promotion of high-yielding techniques was suggested as fol ows： on the basis of certain number of effective ears, number of fil ed grains per ear should be mainly focused with a consideration to grain weight.
基金Foundation item: National Natural Science Foundation of China(No.60372072)
文摘In order to reduce the hidden danger of noise which can be charactered by singularity spectrum, a new algorithm based on wavelet transform modulus maxima method was proposed. Singularity analysis is one of the most promising new approaches for extracting noise hidden information from noisy time series . Because of singularity strength is hard to calculate accurately, a wavelet transform modulus maxima method was used to get singularity spectrum. The singularity spectrum of white noise and aluminium interconnection electromigration noise was calculated and analyzed. The experimental results show that the new algorithm is more accurate than tradition estimating algorithm. The proposed method is feasible and efficient.
基金Supported by National Food High-yield Science and Technology Project(2012BAD04B13-3)~~
文摘Effect of row space and planting density on yield of Miandan No.12 was studied. The test included four row spaces and two planting densities. Specifically, four row spaces were 50, 67, 83 and 100 cm and two planting densities were 42 000 and 48 000 plant/hm2. The results showed that Miandan No.12 reached the highest yield when row space was 50 cm and planting density was 48 000 plantJhm2 and Miandan No.12 got the lowest yield when row space was 100 cm and planting density was 42 000 plants/hm2.
基金Acknowledgments We are grateful to the staff members at Shanghai Synchrotron Radiation Facility for support in diffraction data collection and other members of our group for helpful discussion. This work was supported by grants from the Ministry of Science and Technology of China （2010CB833601, 2006AA02A313, and 2009ZX09503- 009）, the National Natural Science Foundation of China （30730028 and 90713046）, and the Chinese Academy of Sciences （KSCX2-YW-R- 107 and SIBS2008002）.
文摘Interleukin-2 （IL）-2 signaling plays a pivotal role in the activation of immune responses, and drugs that block this pathway have been shown to be effective for the immunosuppression in patients with organ transplantation to alleviate/eliminate allograft rejection. The first humanized monoclonal antibody （mAb） daclizumab falls into this category and shows high specificity and affinity against a key component of the IL-2 receptor complex, namely IL-2Ra. To reveal the molecular mechanism of the inhibition of the IL-2 signaling pathway by dacllzumab, we determined the crystal structures of the daclizumab Fab in free form and in complex with the IL-2Ra ectodomain at 2.6 and 2.8 A resolution, respectively. The daclizumab Fab adopts a similar conformation in the presence or absence of the IL- 2Ra ectodomain. The antigen-binding site of daclizumab is mainly composed of live complementarity determining regions （CDRs） that form a large positively charged surface depression and two flanking patches that are generally hydrophobic. The conformational epitope consists of several discontinuous segments of the IL-2Ru ectodomain, a large portion of which overlaps with the regions that interact with IL-2, suggesting that the binding of daclizumab to IL-2Ra would prevent the IL-2 binding to IL-2Ra and the subsequent formation of the IL-2fIL-2Ra[~/c complex, and therefore block the IL-2 signaling pathway. These results also have implications for the design and development of improved mAb drugs targeting IL-2Ra.
文摘The single ion channel signal is an ionic current that can be recorded by the patch clamp technique. Hidden Markov model (HMM) algorithm has been used to convert the low signal noise ratio (SNR) noisy recording into an idealized quantal one in the case of white background noise. The traditional HMM algorithm is extended and adapted to the colored background noise. A new algorithm called EHMM (Extended HMM) algorithm is proposed, and mainly validated by simulation. Results show that it’s effective.
基金Supported by the National Natural Science Foundation of China(No.81222021,No.30970875,No.90920015,No.61172008 and No.81171423)National Key Technology Research and Development Program of the Ministry of Science and Technology of China(No.2012BAI34B02)Program for New Century Excellent Talents in University of the Ministry of Education of China(No.NCET-10-0618)
文摘A brain-computer interface(BCI)-based electric wheelchair control system was developed, which enables the users to move the wheelchair forward or backward, and turn left or right without any pre-learning. This control system makes use of the amplitude enhancement of alpha-wave blocking in electroencephalogram(EEG) when eyes close for more than 1 s to constitute a BCI for the switch control of wheelchair movements. The system was formed by BCI control panel, data acquisition, signal processing unit and interface control circuit. Eight volunteers participated in the wheelchair control experiments according to the preset routes. The experimental results show that the mean success control rate of all the subjects was 81.3%, with the highest reaching 93.7%. When one subject's triggering time was 2.8 s, i.e., the flashing time of each cycle light was 2.8 s, the average information transfer rate was 8.10 bit/min, with the highest reaching 12.54 bit/min.
文摘The high-accuracy, wide-range frequency estimation algorithm for multi-component signals presented in this paper, is based on a numerical differentiation and central Lagrange interpolation. With the sample sequences, which need at most 7 points and are sampled at a sample frequency of 25600 Hz, and computation sequences, using employed a formulation proposed in this paper, the frequencies of each component of the signal are all estimated at an accuracy of 0.001% over 1 Hz to 800 kHz with the amplitudes of each component of the signal varying from 1 V to 200 V and the phase angle of each component of the signal varying from 0° to 360°. The proposed algorithm needs at most a half cycle for the frequencies of each component of the signal under noisy or non-noisy conditions. A testing example is given to illustrate the proposed algorithm in Matlab environment.
基金The project supported by National Natural Science Foundation of China under Grant No. 10275025 and the Emphases Item of Education Department of Hubei Province under Grant No. 2004X052
文摘On the basis of calculating the steady-state mean normalized intensity fluctuation of a signal-mode laser system driven by both colored pump noise with signal modulation and the quantum noise with cross-correlation between its real and imaginary parts, we analyze the influence of modulation signal, noise, and its correlation form on the statistical fluctuation of the laser system. We have found that when the amplitude of modulation signal weakens and its frequency quickens, the statistical fluctuation will reduce rapidly. The by reducing the intensity of pump noise and quantum noise. statistical fluctuation of the laser system can be restrained Moreover, with prolonging of colored cross-correlation time, the statistical fluctuation of laser system experiences a repeated changing process, that is, from decreasing to augmenting, then to decreasing, and finally to augmenting again. With the decreasing of the value of cross-correlation coe~cient, the statistical fluctuation will decrease too. When the cross-correlation form between the real part and imaginary part of quantum noise is zero correlation, the statistical fluctuation of laser system has a minimum. Compared with the influence of intensity of pump noise, the influence of intensity of quantum noise on the statistical fluctuation is smaller.
基金The National Natural Science Foundation of China, No. 30800382the Youth Science Foundation of Dalian to Professor Hui-Shu Guo, No. 2006B3NS218
文摘AIM: To systematically investigate if cGMP/cGMP- dependent protein kinase G (PKG) signaling pathway may participate in dendroaspis natriuretic peptide (DNP)-induced relaxation of gastric circular smooth muscle. METHODS: The content of cGMP in guinea pig gastric antral smooth muscle tissue and perfusion solution were measured using radioimmunoassay; spontaneous contraction of gastric antral circular muscles recorded using a 4-channel physiograph; and Ca2+-activated K+ currents (IK(Ca)) and spontaneous transient outward currents (STOCs) in isolated gastric antral myocytes were recorded using the whole-cell patch clamp technique. RESULTS: DNP markedly enhanced cGMP levels in gastric antral smooth muscle tissue and in the perfusion medium. DNP induced relaxation in gastricantral circular smooth muscle, which was inhibited by KT5823, a cGMP-dependent PKG inhibitor. DNP increased IK(Ca). This effect was almost completely blocked by KT5823, and partially blocked by LY83583, an inhibitor of guanylate cyclase to change the production of cGMP. DNP also increased STOCs. The effect of DNP on STOCs was abolished in the presence of KT5823, but not affected by KT-5720, a PKA-specific inhibitor. CONCLUSION: DNP activates IK(Ca) and relaxes guinea-pig gastric antral circular smooth muscle via the cGMP/PKG-dependent singling axis instead of cAMP/ PKA pathway.
