高校财务危机管理研究——以天津大学单平炒股事件为例

"单平事件"是天津大学校长单平从1997年到2007年在担任天津大学校长期间,天津大学从动用资金参与炒股到经营校办企业,致使学校财务陷入危机境地的一系列事件,由于单平在任期间,对上述财务事件的"失察和失职",从而给学校财务带来了巨大的损失,引发了学校财务危机。本文拟从危机管理的角度,分析此危机事件的管理过程,揭示此种危机事件的管理规律,以期启发来者,警示后来。

A monolithic integrated medium wave Mercury Cadmium Telluride polarimetric focal plane array

A medium wave(MW)640×512(25μm)Mercury Cadmium Telluride(HgCdTe)polarimetric focal plane array(FPA)was demonstrated.The micro-polarizer array(MPA)has been carefully designed in terms of line grating structure optimization and crosstalk suppression.A monolithic fabrication process with low damage was explored,which was verified to be compatible well with HgCdTe devices.After monolithic integration of MPA,NETD<9.5 mK was still maintained.Furthermore,to figure out the underlying mechanism that dominat⁃ed the extinction ratio(ER),specialized MPA layouts were designed,and the crosstalk was experimentally vali⁃dated as the major source that impacted ER.By expanding opaque regions at pixel edges to 4μm,crosstalk rates from adjacent pixels could be effectively reduced to approximately 2%,and promising ERs ranging from 17.32 to 27.41 were implemented.

Study on High-Eefficient Breeding Technology Platform of Dwarf Male-Sterile Wheat

[Purpose] The paper is to discuss the high-efficient breeding technology platform of dwarf male-sterile wheat.[Method] Conclusion was made upon the development of the creation and application of dwarf male-sterile wheat,and the conception of introducing haploid breeding technology into the technological system of high-efficient breeding of dwarf male-sterile wheat was proposed.[Result] Dwarf male-sterile wheat not only retains the properties of total male abortion of Taigu Genetic Sterile Wheat,steady sterility,and high hybrid rate after open pollination,but also has the characteristic of high dwarfing ability of Aibian No.1,becoming a comparatively ideal population modification means.At present,the application of dwarf male-sterile wheat mainly includes germplasm resources platform of population modification by using dwarf male-sterile wheat,technology platform of constructing new high-efficient breeding system by using dwarf male-sterile wheat,and production platform of using dwarf male-sterile wheat to breed new varieties.Through the introduction of haploid breeding into the already established wheat high-efficient breeding system,a new system of high-efficient biological breeding technology of dwarf male-sterile wheat was constructed theoretically.[Conclusion] The study provides references to the further study and application of dwarf male-sterile wheat.

A method of automatic plane detection without random search

Plane detection is a prerequisite for many computer vision tasks. This paper proposes a new method which can automatically detect planes from two projective images. Firstly, we modify Scott’s feature point matching method by post-processing its result with the concept of similarity, and then get the lines matching according to feature points matching based on the approximate invariance of the features’ distribution between two images. Finally, we group all feature points into subsets in terms of their geometric relations with feature lines as initial sets to estimate homography rather than by a random search strategy (like RANSAC) as in most existing methods. The proposed method is especially suitable to detecting planes in man-made scenes. This method is validated on real images.

Mathematically modeling the main dimensions of self-elevating drilling units

The present status of self-elevating drilling units was analysed. Based on statistics of the main dimensions of self-elevating drilling units, a mathematical model was established using stepwise return procedures and a back-propagation neural network. mathematical model is applicable and reliable. The of the main dimensions of self-elevating drilling Analysis of examples of calculations showed that the model is useful for mastering the essential variations units and can be used for technical and economic analysis as well as in conceptual designs of drilling units.

Arsenic trioxide inhibites transgenic tumor necrosis factor-α promoter activity in vascular smooth muscle cells and THP-1 monocytes in vitro

Aim This study was to evaluate the effect of arsenic trioxide （As2O3） on the transgenic TNF-α promoter activity in cultured vascular smooth muscle cells （VSMCs） and THP-1 monocytes. Methods Human TNF-α promoter was constructed by reporter gene system and was transiently transfected into VSMCs and THP-1 in vitro. The promoter activity was tested by luciferase activity with or without LPS and Ang Ⅱ stimulation, before and after different dosage of As2O3 treatment. Results 1. TNF-α promoter effectively expressed in VSMCs and THP-1 compared with CMV promoter （58.3% and 80.9%, respectively）. Both LPS and Ang Ⅱ significantly up-regulated TNF-α promoter activity （P〈0.05）. 2. As2O3 significantly inhibited, both intact and LPS/Ang Ⅱ stimulated promoter activity, in a dose dependent manner （P〈0.05）, and in both cell type. Conclusion These results manifested that, the inhibition effect of As2O3 on the activity of human TNF-α promoter indicated its potential inhibition on pro-inflammatory cytokine genes expression at transcriptional level and its potential anti-inflammatory property in the cardiovascular system.

SHEsis,a powerful software platform for analyses of linkage disequilibrium,haplotype construction,and genetic association at polymorphism loci

In multiloci-based genetic association studies of complex diseases, a powerful and high efficient tool for analyses oflinkage disequilibrium (LD) between markers, haplotype distributions and many chi-square/p values with a large numberof samples has been sought for long. In order to achieve the goal of obtaining meaningful results directly from raw data,we developed a robust and user-friendly software platform with a series of tools for analysis in association study withhigh efficiency. The platform has been well evaluated by several sets of real data.

Effection of Density on Yield and Yield Components of Major Maize Cultivars in Northern Anhui

Rational close planting is an economical and effective measure to increase crop yield.In order to explore the suitable planting density of major maize cultivars in northern Anhui,we studied the grain number per spike and 1 000-grain weight of three major maize cultivars,including ‘Zhengdan958＇,‘Ludan981＇ and ‘Longping206＇.The effects of planting density on yield and correlated characters were further analyzed.The study was performed at agricultural experiment farms of Suzhou Academy of Agricultural Sciences.The planting density was set from 7 500 to 30 000 plants/hm^2 with an interval of 7 500 plants/hm^2.Water and fertilizer were supplied sufficiently.High yield cultivation method was also used.Based on the high yield achieved,we analyzed the relationship between crop yield and correlated characters.The results showed that,the planting density had the parabolic relation with the yield of ‘Zhengdan958＇ and ‘Longping206＇.The most suitable density of compact type cultivar ‘Zhengdan 958＇ was 73 300 plants/hm^2.The most suitable density of semi-compact type cultivar ‘Longping 206＇ was 68 600 plants/hm^2.The most suitable density of flat type cultivar ‘Ludan981＇ was 45 000-52 500 plants/hm^2.The planting density of compact type cultivar could be increased appropriately.However,it was negatively related to the grain number per spike and 1 000-grain weight if the planting density is out of range.So,Ludan981 should be planted in low density to avoid risk.

Application of uncertainty reasoning based on cloud model in time series prediction

Time series prediction has been successfully used in several application areas, such as meteoro-logical forecasting, market prediction, network traffic forecasting, etc. , and a number of techniques have been developed for modeling and predicting time series. In the traditional exponential smoothing method, a fixed weight is assigned to data history, and the trend changes of time series are ignored. In this paper, an uncertainty reasoning method, based on cloud model, is employed in time series prediction, which uses cloud logic controller to adjust the smoothing coefficient of the simple exponential smoothing method dynamically to fit the current trend of the time series. The validity of this solution was proved by experiments on various data sets.

Oscillating Solitons for （2＋1）-Dimensional Nonlinear Models

Using extended homogeneous balance method and variable separation hypothesis, we found new variable separation solutions with three arbitrary functions of the （2＋1）-dimensional dispersive long-wave equations, Based on derived solutions, we revealed abundant oscillating solitons such as dromion, multi-dromion, solitoff, solitary waves, and so on, by selecting appropriate functions.

Virological response to adefovir monotherapy and the risk of adefovir resistance

AIM:To evaluate virological response to adefovir(ADV) monotherapy and emergence of ADV-resistant mutations in lamivudine(LAM)-resistant chronic hepatitis B patients.METHODS:Seventy-seven patients with documented LAM resistance who were treated with 10 mg/d ADV for>96 wk were analyzed for ADV resistance.RESULTS:At week 48 and 96,eight(10%)and 14(18%)of 77 LAM-resistant patients developed the ADV-resistant strain(rtA181V/T and/or rtN236T mutations),respectively.Hepatitis B virus(HBV)DNA levels during therapy were significantly higher in patients who developed ADV resistance than in those who did not.Incidence of ADV resistance at week 96 was 11%,8%and 6%among patients with complete virological response(HBV DNA level<60 IU/mL);0%,5%and 19%among patients with partial virological response(HBV DNA level≥60 to 2000 IU/mL);and 32%,34% and 33%among patients with inadequate virological response(HBV DNA levels>2000 IU/mL)at week 12,week 24 and week 48,respectively.HBV DNA levels >2000 IU/mL at week 24 showed best performance characteristics in predicting ADV resistance.CONCLUSION:Development of ADV resistance mutations was associated with HBV DNA levels,which could identify patients with LAM resistance who are likely to respond to ADV monotherapy.

Quantum Measurement of Single Electron State by a Mesoscopic Detector

A realistic measurement setup for a system such system measured by a mesoscopie detector,is theoretically as a charged two-state （qubit） or multi-state quantum studied. To properly describe the measurement-induced back-action,a detailed-balance preserved quantum master equation treatment is developed. The established framework is applicable for arbitrary voltages and temperatures.

Characteristic Analysis of Diffraction from the Restricted Output End Surface of Single Mode Planar Waveguide

As for single mode symmetric step refractive index structure dielectric planar optical waveguide, when its output end is restricted, the diffractive field distribution is derived. It can be expressed as the convolution between the Dirac function and the Sinc and Lorenz functions. It is helpful to deepen the recognition of the restricted diffraction. The characteristic of the diffractive field is discussed. The variational curve of the full angle width at half maximum intensity of central bright fringe versus the half width of slit is presented by numerical calculation, and the fitting curve with the exponential function is close to it.

Effect of siRNAs on HSV-1 Plaque Formation and Relative Expression Levels of RR mRNA

RNA interference (RNAi) is a process by which introduced small interfering RNA (siRNA) can cause the specific degradation of mRNA with identical sequences. The human herpes simplex virus type 1 (HSV-1) RR is composed of two distinct homodimeric subunits encoded by UL39 and UL40,respectively. In this study,we applied siRNAs targeting the UL39 and UL40 genes of HSV-1. We showed that synthetic siRNA silenced effectively and specifically UL39 and UL40 mRNA expression and inhibited HSV-1 replication. Our work offers new possibilities for RNAi as a genetic tool for inhibition of HSV-1 replication.

Sheet metal hardening curve determined by laminated sample and its adaptability to sheet forming processes

The hardening curve for sheet metal can be determined from the load-displacement curve of tensile specimen with rectangular cross-section. Therefore,uniaxial compression test on cylinder specimen made from laminated sample is put forward. Considering the influence of anisotropy on hardening properties and the stress state in popular forming process,plane strain compression test on cubic specimen made from laminated sample was advanced. Results show that the deformation range of hardening curves obtained from the presented methods is wide,which meets the need for the application in sheet metal forming processes. In view of the characteristics of methods presented in the paper and the stress strain state of various forming processes,the adaptability of the two methods presented in this paper is given.

Simulation of rock deformation and mechanical characteristics using clump parallel-bond models

To properly simulate hard rock with a high ratio of the uniaxial compressive strength to tensile strength(UCS/TS) and realistic strength-failure envelope,the rock deformation and mechanical characteristics were discussed in detail when the particle simulation method with the clump parallel-bond model(CPBM) was used to conduct a series of numerical experiments at the specimen scale.Meanwhile,the effects of the loading procedure and crack density on the mechanical behavior of a specimen,which was modeled by the particle simulation method with the CPBM,were investigated.The related numerical results have demonstrated that:1) The uniaxial compressive strength(UCS),tensile strength(TS) and elastic modulus are overestimated when the conventional loading procedure is used in the particle simulation method with the CPBM; 2) The elastic modulus,strength and UCS/TS decrease,while Poisson ratio increases with the increase of the crack density in the particle simulation method with the CPBM; 3) The particle simulation method with the CPBM can be used to reproduce a high value of UCS/TS(>10),as well as a high friction angle and reasonable cohesion strength; 4) As the confining pressure increases,both the peak strength of the simulated specimen and the number of microscopic cracks increase,but the ratio of tensile cracks number to shear cracks number decreases in the particle simulation method with the CPBM; 5) Compared with the conventional parallel-bond model,the CPBM can be used to reproduce more accurate results for simulating the rock deformation and mechanical characteristics.

Sirolimus,bevacizumab,5-Fluorouracil and irinotecan for advanced colorectal cancer:A pilot study

AIM： To evaluate the efficacy and the safety of combined 5-Fluorouracil, irinotecan, bevacizumab and sirolimus in refractory advanced colorectal carcinoma. METHODS： We initiated a regimen with at day 1 an injection （iv） of bevacizumab at 5 mg/kg, followed by 180 mg/m^2 irinotecan, followed by Leucovorin 400 mg/m^2, followed by a 5-Fluorouracil bolus 400 mg/m^2 and a 46-h infusion 2400 mg/m^2. Sirolimus was given orally as continuous administration of 2 mg twice a day every days. This treatment was repeated every 14 d. RESULTS： A total of 12 patients were enrolled. All patients presented with metastatic disease that had failed at least three lines of chemotherapy that contained oxaliplatin, irinotecan and bevacizumab. Cetuximab failure was also observed in all K-Ras wildtype patients. The median number of cycles was 8.5 （range 2-20） and clinical benefit was observed in eight patients. The median time to progression was 5 mo and the median survival was 8 too. Grade 3 neutropenia developed in four patients, and grade 3 diarrhea and stomatitis in two.CONCLUSION： The combination regimen of 5-Fluorouracil,irinotecan, bevacizumab and sirolimus in advanced colorectal carcinoma after failure of dassical be.absent is feasible and promising. Further evaluation of this combination is required.

STUDIES OF SURFACE GRINDING TEMPERATURE AFFECTED BY DIFFERENT GRINDING WAYS OF SILICON WAFER

The surface grinding temperature of the silicon wafer ground by diamond wheels is studied.Rudimentally,the properties of the surface grinding temperature generated by two grinding methods,ground by straight and cup wheels respectively,are analyzed.In addition,considering the effects of grain size and grinding depth on surface grinding temperature during these two grinding processes,significant results and conclusions are obtained from experimental research.