A 48-year-old female with severe ulcerative colitis refractory to conventional therapy was referred to our facility for management. The patient showed extensive ulcerative colitis since the age of 20 years and had fai...A 48-year-old female with severe ulcerative colitis refractory to conventional therapy was referred to our facility for management. The patient showed extensive ulcerative colitis since the age of 20 years and had failed therapy with 5-aminosalicylic acid agents and azathioprine. The disease remained active despite treatment with steroids and cyclosporine. The clinical and endoscopic parameters were consistent with severe disease. Infectious precipitants were ruled out. Given the severity of the disease and in order to avoid a colectomy, we started the patient on infliximab therapy. A dramatic clinical and endoscopic response was observed and she remained in remission at the end of a 1-year follow-up period. We discuss findings in the literature regarding the use ofinfliximab therapy in patients with ulcerative colitis who have failed steroids and cyclosporine.展开更多
Opsaridium microlepis migrates for spawning during the rainy season (November to May) to major affluent rivers. Linthipe River is one of the major rivers, into which this species migrates. Determination of reproduct...Opsaridium microlepis migrates for spawning during the rainy season (November to May) to major affluent rivers. Linthipe River is one of the major rivers, into which this species migrates. Determination of reproductive seasonality of O. microlepis is paramount in the improved management of this endangered species. Reproductive seasonality ofO. microlepis in the Linthipe River in Central Malawi was estimated using 546 specimens for 12 months. The GSI (Gonadosomatic Index) ranged between 5.6% and 13% for females and between 0.3% and 1.4% for males, respectively. GSI variation between the months was significantly different (one-way ANOVA (analysis of variance), P 〈 0.05). The peak breeding activity was observed between January to April. This was at the onset of rainy season while the condition factor of O. microlepis was found to be variable with lowest value in the month of August. The study revealed that for O. microlepis fishery to be sustainably exploited, proper management regimes should be instituted along the migratory rivers during the peak breeding periods. These sustainable methods need to be managed in a participatory manner together with the majority of people living along these rivers.展开更多
According to the analysis of the problem of contract management, financial settlement and placement of coal trucks in coal business, a study is made on the coal management system. This system combines B/S and C/S toge...According to the analysis of the problem of contract management, financial settlement and placement of coal trucks in coal business, a study is made on the coal management system. This system combines B/S and C/S together, and it also uses three-tire application of ASP.NET which sets up a business subsystem based on functional module management in vehicle. Additionally, MFC solves the problems in weighing management systems. This system goes with unit testing, integration testing, and system testing, and the whole process realizes an effective monitoring from coal trucks applying for delivery, checking in, and weighing to checking out. Besides, it also secures precise and accurate weighing data, and deals with the new coming coal contract in a faster way. The real project indicates this system wins a very good reputation and it is worthy of spreading in a broader context.展开更多
In this paper,we proposed a new n-channel MOS single event transient(SET) mitigation technique,which is called the open guard transistor(OGT) technique.This hardening scheme is compared with several classical n-channe...In this paper,we proposed a new n-channel MOS single event transient(SET) mitigation technique,which is called the open guard transistor(OGT) technique.This hardening scheme is compared with several classical n-channel MOS hardening structures through 3-D TCAD simulations.The results show that this scheme presents about 35% improvements over the unhardened scheme for mitigating the SET pulse,and its upgrade,the 2-fringe scheme,takes on even more than 50% improvements over the unhardened one.This makes significant sense for the semi-conductor device reliability.展开更多
Single-walled carbon nanotubes (SWNTs) possess high conductivity, mechanical strength, transparency, and flexibility, and are thus suitable for use in flexible electronics, transparent electrodes, and energy-storage...Single-walled carbon nanotubes (SWNTs) possess high conductivity, mechanical strength, transparency, and flexibility, and are thus suitable for use in flexible electronics, transparent electrodes, and energy-storage and energy-harvesting applications. However, to exploit these properties, SWNTs must be de-bundled in a surfactant solution to permit processing and use. We report a new method to prepare a SWNT-based transparent conducting film (TCF) using the diazo dye 3,3'-([1,1'-biphenyl]-4,4'-diyl)bis(4-amino naphthalene-1-sulfonic acid), commonly known as Congo red (CR), as a dispersant. Uniform 20-nm-thick TCFs were prepared on rigid glass and flexible polyethylene terephthalate (PET) substrates. The CR-SWNT dispersion and the CR-SWNT TCFs were characterized via UV-Vis-NIR, Raman spectroscopy, FT-IR spectroscopy, transmission electron microscopy (TEM), field-emission scanning electron microscopy (FE-SEM) and dynamic light scattering (DLS) measurements. The sheet resistivity of the CRSWNT TCF was -34 ±6.6 Ω/□ with a transmittance of 81% at 550 nm, comparable to that of indium tin oxide-based films. Unlike SWNT dispersions prepared in common surfactants, such as sodium dodecyl sulfate (SDS), sodium cholate (SC), and Triton X-100, the CR-SWNT dispersion was amenable to forming TCF by drop coating. The CR-SWNT TCF was also very stable, maintaining a very low sheet resistivity even after 1,000 consecutive bending cycles of 8 mm bending radius. Further, manganese dioxide (MnO2) was electrochemically deposited on the CR-SWNT-PET film (MnO2-CR-SWNT-PET). The as-prepared MnO2- CR-SWNT-PET electrode exhibited high specific capacitance and bendability, demonstrating promise as a candidate electrode material for flexible supercapacitors.展开更多
A strategy to prepare horizontally aligned single-walled carbon nanotubes(SWNTs) at moderate temperatures(≤600 ℃) were developed.Using ferocene as the catalyst precursor,Fe nanoparticles are formed in the gaseous ph...A strategy to prepare horizontally aligned single-walled carbon nanotubes(SWNTs) at moderate temperatures(≤600 ℃) were developed.Using ferocene as the catalyst precursor,Fe nanoparticles are formed in the gaseous phase and catalyze the nucleation and growth of SWNTs in situ.Then the resultant SWNTs are deposited onto the substrates downstream and aligned by the surface lattice of the ST-cut single crystal quartz.The preparation of SWNT arrays at moderate temperatures is important for combining the tube growth with device fabrication.展开更多
The global demand for resource sustainability is growing. Thus, the development of single-source, environment-friendly colloidal semiconductor nanocrystal (NC) phosphors with broadband emission spectra is highly des...The global demand for resource sustainability is growing. Thus, the development of single-source, environment-friendly colloidal semiconductor nanocrystal (NC) phosphors with broadband emission spectra is highly desirable for use as color converters in white light-emitting diodes (WLEDs). We report herein the gram-scale synthesis of single-source, cadmium-free, dual-emissive Mn-doped Zn-Cu-In-S NCs (d-dots) by a simple, non-injection, low-cost, one-pot approach. This synthesis method led to the formation of NCs with continuously varying compositions in a radial direction because each precursor had a different reactivity. Consequently, the d-dots exhibited two emission bands, one that could be attributed to Mn emission and a second that could be ascribed to the band edge of the Zn-Cu-In-S NCs. The emission peaks assigned to band edge were tunable by modifying the particle size and composition. The prepared d-dots also exhibited the characteristic zero self-absorption, a quantum yield of 46%, and good thermal stability. Combining a commercial blue light-emitting diode (LED) chip with optimized d-dots as color converters gave a high color rendering index of up to 90, Commission Internationale de l'eclairage color coordinates of (0.332, 0.321), and a correlated color temperature of 5,680 K. These results suggest that cadmium-free, thermally stable, single-phase d-dot phosphors have potential applications in WLEDs.展开更多
The large-scale assembly and fabrication method for single-walled carbon nanotube(SWCNT) nano devices was implemented.Assembly of SWCNT field effect transistor(FET) was realized by floating potential dielectrophoresis...The large-scale assembly and fabrication method for single-walled carbon nanotube(SWCNT) nano devices was implemented.Assembly of SWCNT field effect transistor(FET) was realized by floating potential dielectrophoresis approach.The simulation of floating potential distribution of the chip was performed by comsol multiphysics coupling software.Six hundred devices were assembled on the area of less than one square centimeter.The fabricated devices were characterized by atomic force microscopy and scanning electron microscopy.The experimental results showed that large-scale assembly had been realized,and the success rate of ideal assembly for SWCNT FET had been assessed.展开更多
文摘A 48-year-old female with severe ulcerative colitis refractory to conventional therapy was referred to our facility for management. The patient showed extensive ulcerative colitis since the age of 20 years and had failed therapy with 5-aminosalicylic acid agents and azathioprine. The disease remained active despite treatment with steroids and cyclosporine. The clinical and endoscopic parameters were consistent with severe disease. Infectious precipitants were ruled out. Given the severity of the disease and in order to avoid a colectomy, we started the patient on infliximab therapy. A dramatic clinical and endoscopic response was observed and she remained in remission at the end of a 1-year follow-up period. We discuss findings in the literature regarding the use ofinfliximab therapy in patients with ulcerative colitis who have failed steroids and cyclosporine.
文摘Opsaridium microlepis migrates for spawning during the rainy season (November to May) to major affluent rivers. Linthipe River is one of the major rivers, into which this species migrates. Determination of reproductive seasonality of O. microlepis is paramount in the improved management of this endangered species. Reproductive seasonality ofO. microlepis in the Linthipe River in Central Malawi was estimated using 546 specimens for 12 months. The GSI (Gonadosomatic Index) ranged between 5.6% and 13% for females and between 0.3% and 1.4% for males, respectively. GSI variation between the months was significantly different (one-way ANOVA (analysis of variance), P 〈 0.05). The peak breeding activity was observed between January to April. This was at the onset of rainy season while the condition factor of O. microlepis was found to be variable with lowest value in the month of August. The study revealed that for O. microlepis fishery to be sustainably exploited, proper management regimes should be instituted along the migratory rivers during the peak breeding periods. These sustainable methods need to be managed in a participatory manner together with the majority of people living along these rivers.
文摘According to the analysis of the problem of contract management, financial settlement and placement of coal trucks in coal business, a study is made on the coal management system. This system combines B/S and C/S together, and it also uses three-tire application of ASP.NET which sets up a business subsystem based on functional module management in vehicle. Additionally, MFC solves the problems in weighing management systems. This system goes with unit testing, integration testing, and system testing, and the whole process realizes an effective monitoring from coal trucks applying for delivery, checking in, and weighing to checking out. Besides, it also secures precise and accurate weighing data, and deals with the new coming coal contract in a faster way. The real project indicates this system wins a very good reputation and it is worthy of spreading in a broader context.
基金supported by the National Natural Science Foundation of China (Grant Nos. 60836004 and 61006070)
文摘In this paper,we proposed a new n-channel MOS single event transient(SET) mitigation technique,which is called the open guard transistor(OGT) technique.This hardening scheme is compared with several classical n-channel MOS hardening structures through 3-D TCAD simulations.The results show that this scheme presents about 35% improvements over the unhardened scheme for mitigating the SET pulse,and its upgrade,the 2-fringe scheme,takes on even more than 50% improvements over the unhardened one.This makes significant sense for the semi-conductor device reliability.
文摘Single-walled carbon nanotubes (SWNTs) possess high conductivity, mechanical strength, transparency, and flexibility, and are thus suitable for use in flexible electronics, transparent electrodes, and energy-storage and energy-harvesting applications. However, to exploit these properties, SWNTs must be de-bundled in a surfactant solution to permit processing and use. We report a new method to prepare a SWNT-based transparent conducting film (TCF) using the diazo dye 3,3'-([1,1'-biphenyl]-4,4'-diyl)bis(4-amino naphthalene-1-sulfonic acid), commonly known as Congo red (CR), as a dispersant. Uniform 20-nm-thick TCFs were prepared on rigid glass and flexible polyethylene terephthalate (PET) substrates. The CR-SWNT dispersion and the CR-SWNT TCFs were characterized via UV-Vis-NIR, Raman spectroscopy, FT-IR spectroscopy, transmission electron microscopy (TEM), field-emission scanning electron microscopy (FE-SEM) and dynamic light scattering (DLS) measurements. The sheet resistivity of the CRSWNT TCF was -34 ±6.6 Ω/□ with a transmittance of 81% at 550 nm, comparable to that of indium tin oxide-based films. Unlike SWNT dispersions prepared in common surfactants, such as sodium dodecyl sulfate (SDS), sodium cholate (SC), and Triton X-100, the CR-SWNT dispersion was amenable to forming TCF by drop coating. The CR-SWNT TCF was also very stable, maintaining a very low sheet resistivity even after 1,000 consecutive bending cycles of 8 mm bending radius. Further, manganese dioxide (MnO2) was electrochemically deposited on the CR-SWNT-PET film (MnO2-CR-SWNT-PET). The as-prepared MnO2- CR-SWNT-PET electrode exhibited high specific capacitance and bendability, demonstrating promise as a candidate electrode material for flexible supercapacitors.
基金supported by Ministry of Science and Technology of China(2016YFA0201904)the National Natural Science Foundation of China(21631002,U1632119)
文摘A strategy to prepare horizontally aligned single-walled carbon nanotubes(SWNTs) at moderate temperatures(≤600 ℃) were developed.Using ferocene as the catalyst precursor,Fe nanoparticles are formed in the gaseous phase and catalyze the nucleation and growth of SWNTs in situ.Then the resultant SWNTs are deposited onto the substrates downstream and aligned by the surface lattice of the ST-cut single crystal quartz.The preparation of SWNT arrays at moderate temperatures is important for combining the tube growth with device fabrication.
基金This work was supported by the National Natural Science Foundation of China (Nos. 21373097 and 51072067) and the National Basic Research Program of China (No. 2011CB935800).
文摘The global demand for resource sustainability is growing. Thus, the development of single-source, environment-friendly colloidal semiconductor nanocrystal (NC) phosphors with broadband emission spectra is highly desirable for use as color converters in white light-emitting diodes (WLEDs). We report herein the gram-scale synthesis of single-source, cadmium-free, dual-emissive Mn-doped Zn-Cu-In-S NCs (d-dots) by a simple, non-injection, low-cost, one-pot approach. This synthesis method led to the formation of NCs with continuously varying compositions in a radial direction because each precursor had a different reactivity. Consequently, the d-dots exhibited two emission bands, one that could be attributed to Mn emission and a second that could be ascribed to the band edge of the Zn-Cu-In-S NCs. The emission peaks assigned to band edge were tunable by modifying the particle size and composition. The prepared d-dots also exhibited the characteristic zero self-absorption, a quantum yield of 46%, and good thermal stability. Combining a commercial blue light-emitting diode (LED) chip with optimized d-dots as color converters gave a high color rendering index of up to 90, Commission Internationale de l'eclairage color coordinates of (0.332, 0.321), and a correlated color temperature of 5,680 K. These results suggest that cadmium-free, thermally stable, single-phase d-dot phosphors have potential applications in WLEDs.
基金supported by the National Natural Science Foundation of China (Grant No. 51005230)China Postdoctoral Science Foundation(Grant No. 2012M520654)the Education Department of Liaoning Province Science and Technology Research Projects (Grant No. L2012213)
文摘The large-scale assembly and fabrication method for single-walled carbon nanotube(SWCNT) nano devices was implemented.Assembly of SWCNT field effect transistor(FET) was realized by floating potential dielectrophoresis approach.The simulation of floating potential distribution of the chip was performed by comsol multiphysics coupling software.Six hundred devices were assembled on the area of less than one square centimeter.The fabricated devices were characterized by atomic force microscopy and scanning electron microscopy.The experimental results showed that large-scale assembly had been realized,and the success rate of ideal assembly for SWCNT FET had been assessed.