An approach based on the superelement theory is proposed, and it is applied to model the car's body-in-white as well as to dynamic simulation and optimization. This approach can improve the calculation speed and d...An approach based on the superelement theory is proposed, and it is applied to model the car's body-in-white as well as to dynamic simulation and optimization. This approach can improve the calculation speed and do the dynamic optimization among substructures respectively in the car's body design. To meet the car's design of harshness, a dynamic optimal design model, based on the mean square of vertical displacement response at two points of the car floor, is proposed. Satisfactory results are achieved.展开更多
The pozzolanic activity of coal gangue, which is calcining at 500 to 1 000 ℃, differs distinctly. The simplex-centroid design with upper and lower bounds of component proportion is adopted to study the compressive st...The pozzolanic activity of coal gangue, which is calcining at 500 to 1 000 ℃, differs distinctly. The simplex-centroid design with upper and lower bounds of component proportion is adopted to study the compressive strength of mortars made with ternary blends of cement, activated coal gangue and fly ash. Based on the results of a minimum of seven design points, three special cubic polynomial models are used to establish the strength predicating equations at different ages for mortars. Five experimental checkpoints were also designed to verify the precision of the equations. The most frequent errors of the predicted values are within 3%. A simple and practical way is provided for determining the optimal proportion of two admixtures when they are used in concrete.展开更多
A behavioral model of the photodiode is presented.The model describes the relationship between photocurrent and incident optical power,and it also illustrates the impact of the reverse bias to the variation of the jun...A behavioral model of the photodiode is presented.The model describes the relationship between photocurrent and incident optical power,and it also illustrates the impact of the reverse bias to the variation of the junction capacitance.According to this model,the photodiode and a CMOS receiver circuit are simulated and designed simultaneously under a universal circuit simulation environment.展开更多
[Objective] This study aimed to optimize the PCR amplification conditions for random ssDNA pool in SELEX technology. [Method] L16（45） orthogonal experimental design was adopted for optimization of five important fac...[Objective] This study aimed to optimize the PCR amplification conditions for random ssDNA pool in SELEX technology. [Method] L16（45） orthogonal experimental design was adopted for optimization of five important factors affecting PCR reaction system for random single-stranded DNA pool including Mg2＋ concentration, dNTP concentration, amount of Taq DNA polymerase, primer concentration and amount of random single-stranded DNA pool at four levels. Meanwhile, the annealing temperature and number of PCR reaction cycles were optimized to establish the optimal reaction system and PCR procedure. [Result] The optimal combination of PCR reaction system for random ssDNA pool was obtained, with a total system volume of 20 μl containing 2.0 μl of 10 × Buffer, 0.5 ng of random ssDNA pool, 2.5 mmol/L Mg2＋, 0.25 mmol/L dNTP Mixture, 0.6 μmol/L upstream and downstream primers and 1.5 U of Taq DNA polymerase; the optimal annealing temperature was 68 ℃ and the optimal number of cycles was 12. Under the above conditions, clear and stable bands with high specificity for random ssDNA pool were amplified. [Conclusion] This study laid the foundation for selection of parameters with higher specificity in SELEX technology.展开更多
The hardware optimization technique of mono similarity system generation is presented based on hardware/software(HW/SW) co design.First,the coarse structure of sub graphs' matching based on full customized HW...The hardware optimization technique of mono similarity system generation is presented based on hardware/software(HW/SW) co design.First,the coarse structure of sub graphs' matching based on full customized HW/SW co design is put forward.Then,a universal sub graphs' combination method is discussed.Next,a more advanced vertexes' compression algorithm based on sub graphs' combination method is discussed with great emphasis.Experiments are done successfully with perfect results verifying all the formulas and the methods above.展开更多
Triple-negative breast cancer(TNBC) is diagnosed more frequently in younger and premenopausal women and is highly prevalent in African American women. TNBC is a term derived from tumors that are characterized by the a...Triple-negative breast cancer(TNBC) is diagnosed more frequently in younger and premenopausal women and is highly prevalent in African American women. TNBC is a term derived from tumors that are characterized by the absence of ER, Pg R, and HER2. So patients with TNBC do not benefit from hormonal or trastuzumab-based therapies. TNBCs are biologically aggressive, although some reports suggest that they respond to chemotherapy better than other types of breast cancer, prognosis remains poor. This is due to: shortened disease-free interval in the adjuvant and neoadjuvant setting and a more aggressive course in the metastatic setting.展开更多
In this work, power efficient butterfly unit based FFT architecture is presented. The butterfly unit is designed using floating-point fused arithmetic units. The fused arithmetic units include two-term dot product uni...In this work, power efficient butterfly unit based FFT architecture is presented. The butterfly unit is designed using floating-point fused arithmetic units. The fused arithmetic units include two-term dot product unit and add-subtract unit. In these arithmetic units, operations are performed over complex data values. A modified fused floating-point two-term dot product and an enhanced model for the Radix-4 FFT butterfly unit are proposed. The modified fused two-term dot product is designed using Radix-16 booth multiplier. Radix-16 booth multiplier will reduce the switching activities compared to Radix-8 booth multiplier in existing system and also will reduce the area required. The proposed architecture is implemented efficiently for Radix-4 decimation in time(DIT) FFT butterfly with the two floating-point fused arithmetic units. The proposed enhanced architecture is synthesized, implemented, placed and routed on a FPGA device using Xilinx ISE tool. It is observed that the Radix-4 DIT fused floating-point FFT butterfly requires 50.17% less space and 12.16% reduced power compared to the existing methods and the proposed enhanced model requires 49.82% less space on the FPGA device compared to the proposed design. Also, reduced power consumption is addressed by utilizing the reusability technique, which results in 11.42% of power reduction of the enhanced model compared to the proposed design.展开更多
This paper seeks to enhance the understanding that the horizontal stresses build up and release during coal pillar loading and unloading(post-failure) drawing upon three decades of observations, geomechanical monitori...This paper seeks to enhance the understanding that the horizontal stresses build up and release during coal pillar loading and unloading(post-failure) drawing upon three decades of observations, geomechanical monitoring and numerical modeling in bump-prone U.S. mines. The focus is on induced horizontal stress in mine pillars and surrounding strata as highly stressed pillars punch into the roof and floor, causing shear failure and buckling of strata; under stiff stratigraphic units of some western US mines, these events could be accompanied by violent failure of pillar cores. Pillar punching eventually results in tensile stresses at the base of the pillar, facilitating transition into the post-failure regime; this transition will be nonviolent if certain conditions are met, notably the presence of interbedded mudstones with low shear strength properties and proper mine designs for controlling seismicity and dynamic loads. The study clearly shows high confining stress build-up in coal pillars resulting in up to twice higher peak vertical stress and high strain energy accumulations in some western US mines in comparison with peak stresses predicted using common empirical pillar design methods. It is the unstable release of this strain energy that can cause significant damage resulting from pillar dilation and ground movements. These forces are much greater than the capacity of most common internal support systems, resulting in horizontal stressinduced roof falls locally, in mines under unremarkable far-field horizontal stress. Attention should be placed on pillar designs as increasing support density may prove to be ineffective. This mechanism is analyzed using field measurements and generic finite-difference stress analyses. The study confirms the higher load carrying capacity of confinement-controlled coal seams in comparison with structurally controlled coal seams. Such significant differences in confining stresses are not taken into account when estimating peak pillar strength using most common empirical techniques such as those proposed by Bieniawski and Salamon. While using lower pillar strength estimates may be considered conservative,it underestimates the actual capacity of pillars in accumulating much higher stress and strain energies,misleading the designer and inadvertently diminishing mine safety. The role of induced horizontal stress in mine pillars and surrounding strata is emphasized in coal pillar mechanics of violent failure. The triggering mechanism for the violent events is sudden loss of pillar confinement due to dynamic loading resulting from failure of overlying stiff and strong strata. Evidence of such mechanism is noted in the field by observed red-dust at the coal-rock interfaces at the location of coal bumps and irregular, periodic caving in room-and-pillar mines quantified through direct pressure measurements in the gob.展开更多
Aim To design and experimentally study an 80C196KC-based SRD (switched re- luctance motor drive drive sytem) controller,Methods with the guidelines of the digitized SRD system controller,the circuit design and softwar...Aim To design and experimentally study an 80C196KC-based SRD (switched re- luctance motor drive drive sytem) controller,Methods with the guidelines of the digitized SRD system controller,the circuit design and software programming were completed,and a relevantexperimental system was PUT forward to test the newly designed controller.Result The experi-mental study showed that the newlydesigned controller had good speed-adjusting characteristicfor a switched reluctance motor ,its stable error was less than 5% and its full-load startingtime was shorter than 1.8s .Conclusion The new controller has reasonable circuit design and suitable controlling algorithm,and it is a feasible SRD system controller design scheme.展开更多
This work was focused on the model-based design method of two-axis four-actuator(TAFA) fast steering mirror system(FSM), in order to improve the design efficiency. The structure and operation principle commonality of ...This work was focused on the model-based design method of two-axis four-actuator(TAFA) fast steering mirror system(FSM), in order to improve the design efficiency. The structure and operation principle commonality of normal TAFA FSM were investigated. Based on the structure and the commonality, the conditions of single-axis idea, high-frequency resonance and coupling were modeled gradually. Combining these models, a holonomic system model was established to reflect and predict the performance of TAFA FSM. A model-based design method was proposed based on the holonomic system model. The design flow and design concept of the method were described. In accordance with the method, a TAFA FSM was designed. Simulations and experiments of the FSM were done, and the results of them were compared. The compared results indicate that the holonomic system model can well reflect and predict the performance of TAFA FSM. The bandwidth of TAFA FSM is more than 250 Hz; adjust time is less than 15 ms;overshoot is less than 8%; position accuracy is better than 10 μrad; the FSM prototype can satisfy the requirements.展开更多
Two design axioms and axiomatic approach were discussed. As an example of application, design process of a new style single prop was illustrated in term of axi- oms.
Application-specific data processing units (DPUs) are commonly adopted for operational control and data processing in space missions. To overcome the limitations of traditional radiation-hardened or fully commercial d...Application-specific data processing units (DPUs) are commonly adopted for operational control and data processing in space missions. To overcome the limitations of traditional radiation-hardened or fully commercial design approaches, a reconfigurable-system-on-chip (RSoC) solution based on state-of-the-art FPGA is introduced. The flexibility and reliability of this approach are outlined, and the requirements for an enhanced RSoC design with in-flight reconfigurability for space applications are presented. This design has been demonstrated as an on-board computer prototype, providing an in-flight reconfigurable DPU design approach using integrated hardwired processors.展开更多
文摘An approach based on the superelement theory is proposed, and it is applied to model the car's body-in-white as well as to dynamic simulation and optimization. This approach can improve the calculation speed and do the dynamic optimization among substructures respectively in the car's body design. To meet the car's design of harshness, a dynamic optimal design model, based on the mean square of vertical displacement response at two points of the car floor, is proposed. Satisfactory results are achieved.
基金The National Basic Research Program of China (973Program)(No2000CB610703)
文摘The pozzolanic activity of coal gangue, which is calcining at 500 to 1 000 ℃, differs distinctly. The simplex-centroid design with upper and lower bounds of component proportion is adopted to study the compressive strength of mortars made with ternary blends of cement, activated coal gangue and fly ash. Based on the results of a minimum of seven design points, three special cubic polynomial models are used to establish the strength predicating equations at different ages for mortars. Five experimental checkpoints were also designed to verify the precision of the equations. The most frequent errors of the predicted values are within 3%. A simple and practical way is provided for determining the optimal proportion of two admixtures when they are used in concrete.
文摘A behavioral model of the photodiode is presented.The model describes the relationship between photocurrent and incident optical power,and it also illustrates the impact of the reverse bias to the variation of the junction capacitance.According to this model,the photodiode and a CMOS receiver circuit are simulated and designed simultaneously under a universal circuit simulation environment.
基金Supported by Central University Basic Research Operating Expenses Special Fund(XDJK2011C026)Southwest University Doctoral Fund(09BSR04)~~
文摘[Objective] This study aimed to optimize the PCR amplification conditions for random ssDNA pool in SELEX technology. [Method] L16（45） orthogonal experimental design was adopted for optimization of five important factors affecting PCR reaction system for random single-stranded DNA pool including Mg2＋ concentration, dNTP concentration, amount of Taq DNA polymerase, primer concentration and amount of random single-stranded DNA pool at four levels. Meanwhile, the annealing temperature and number of PCR reaction cycles were optimized to establish the optimal reaction system and PCR procedure. [Result] The optimal combination of PCR reaction system for random ssDNA pool was obtained, with a total system volume of 20 μl containing 2.0 μl of 10 × Buffer, 0.5 ng of random ssDNA pool, 2.5 mmol/L Mg2＋, 0.25 mmol/L dNTP Mixture, 0.6 μmol/L upstream and downstream primers and 1.5 U of Taq DNA polymerase; the optimal annealing temperature was 68 ℃ and the optimal number of cycles was 12. Under the above conditions, clear and stable bands with high specificity for random ssDNA pool were amplified. [Conclusion] This study laid the foundation for selection of parameters with higher specificity in SELEX technology.
文摘The hardware optimization technique of mono similarity system generation is presented based on hardware/software(HW/SW) co design.First,the coarse structure of sub graphs' matching based on full customized HW/SW co design is put forward.Then,a universal sub graphs' combination method is discussed.Next,a more advanced vertexes' compression algorithm based on sub graphs' combination method is discussed with great emphasis.Experiments are done successfully with perfect results verifying all the formulas and the methods above.
文摘Triple-negative breast cancer(TNBC) is diagnosed more frequently in younger and premenopausal women and is highly prevalent in African American women. TNBC is a term derived from tumors that are characterized by the absence of ER, Pg R, and HER2. So patients with TNBC do not benefit from hormonal or trastuzumab-based therapies. TNBCs are biologically aggressive, although some reports suggest that they respond to chemotherapy better than other types of breast cancer, prognosis remains poor. This is due to: shortened disease-free interval in the adjuvant and neoadjuvant setting and a more aggressive course in the metastatic setting.
文摘In this work, power efficient butterfly unit based FFT architecture is presented. The butterfly unit is designed using floating-point fused arithmetic units. The fused arithmetic units include two-term dot product unit and add-subtract unit. In these arithmetic units, operations are performed over complex data values. A modified fused floating-point two-term dot product and an enhanced model for the Radix-4 FFT butterfly unit are proposed. The modified fused two-term dot product is designed using Radix-16 booth multiplier. Radix-16 booth multiplier will reduce the switching activities compared to Radix-8 booth multiplier in existing system and also will reduce the area required. The proposed architecture is implemented efficiently for Radix-4 decimation in time(DIT) FFT butterfly with the two floating-point fused arithmetic units. The proposed enhanced architecture is synthesized, implemented, placed and routed on a FPGA device using Xilinx ISE tool. It is observed that the Radix-4 DIT fused floating-point FFT butterfly requires 50.17% less space and 12.16% reduced power compared to the existing methods and the proposed enhanced model requires 49.82% less space on the FPGA device compared to the proposed design. Also, reduced power consumption is addressed by utilizing the reusability technique, which results in 11.42% of power reduction of the enhanced model compared to the proposed design.
文摘This paper seeks to enhance the understanding that the horizontal stresses build up and release during coal pillar loading and unloading(post-failure) drawing upon three decades of observations, geomechanical monitoring and numerical modeling in bump-prone U.S. mines. The focus is on induced horizontal stress in mine pillars and surrounding strata as highly stressed pillars punch into the roof and floor, causing shear failure and buckling of strata; under stiff stratigraphic units of some western US mines, these events could be accompanied by violent failure of pillar cores. Pillar punching eventually results in tensile stresses at the base of the pillar, facilitating transition into the post-failure regime; this transition will be nonviolent if certain conditions are met, notably the presence of interbedded mudstones with low shear strength properties and proper mine designs for controlling seismicity and dynamic loads. The study clearly shows high confining stress build-up in coal pillars resulting in up to twice higher peak vertical stress and high strain energy accumulations in some western US mines in comparison with peak stresses predicted using common empirical pillar design methods. It is the unstable release of this strain energy that can cause significant damage resulting from pillar dilation and ground movements. These forces are much greater than the capacity of most common internal support systems, resulting in horizontal stressinduced roof falls locally, in mines under unremarkable far-field horizontal stress. Attention should be placed on pillar designs as increasing support density may prove to be ineffective. This mechanism is analyzed using field measurements and generic finite-difference stress analyses. The study confirms the higher load carrying capacity of confinement-controlled coal seams in comparison with structurally controlled coal seams. Such significant differences in confining stresses are not taken into account when estimating peak pillar strength using most common empirical techniques such as those proposed by Bieniawski and Salamon. While using lower pillar strength estimates may be considered conservative,it underestimates the actual capacity of pillars in accumulating much higher stress and strain energies,misleading the designer and inadvertently diminishing mine safety. The role of induced horizontal stress in mine pillars and surrounding strata is emphasized in coal pillar mechanics of violent failure. The triggering mechanism for the violent events is sudden loss of pillar confinement due to dynamic loading resulting from failure of overlying stiff and strong strata. Evidence of such mechanism is noted in the field by observed red-dust at the coal-rock interfaces at the location of coal bumps and irregular, periodic caving in room-and-pillar mines quantified through direct pressure measurements in the gob.
文摘Aim To design and experimentally study an 80C196KC-based SRD (switched re- luctance motor drive drive sytem) controller,Methods with the guidelines of the digitized SRD system controller,the circuit design and software programming were completed,and a relevantexperimental system was PUT forward to test the newly designed controller.Result The experi-mental study showed that the newlydesigned controller had good speed-adjusting characteristicfor a switched reluctance motor ,its stable error was less than 5% and its full-load startingtime was shorter than 1.8s .Conclusion The new controller has reasonable circuit design and suitable controlling algorithm,and it is a feasible SRD system controller design scheme.
基金Projects(51135009)supported by the National Natural Science Foundation of China
文摘This work was focused on the model-based design method of two-axis four-actuator(TAFA) fast steering mirror system(FSM), in order to improve the design efficiency. The structure and operation principle commonality of normal TAFA FSM were investigated. Based on the structure and the commonality, the conditions of single-axis idea, high-frequency resonance and coupling were modeled gradually. Combining these models, a holonomic system model was established to reflect and predict the performance of TAFA FSM. A model-based design method was proposed based on the holonomic system model. The design flow and design concept of the method were described. In accordance with the method, a TAFA FSM was designed. Simulations and experiments of the FSM were done, and the results of them were compared. The compared results indicate that the holonomic system model can well reflect and predict the performance of TAFA FSM. The bandwidth of TAFA FSM is more than 250 Hz; adjust time is less than 15 ms;overshoot is less than 8%; position accuracy is better than 10 μrad; the FSM prototype can satisfy the requirements.
文摘Two design axioms and axiomatic approach were discussed. As an example of application, design process of a new style single prop was illustrated in term of axi- oms.
基金Supported by Innovative Program of the Chinese Academy of Sciences (No. KGCY-SYW-407-02)Grand International Cooperation Foundation of Shanghai Science and Technology Commission (No. 052207046)
文摘Application-specific data processing units (DPUs) are commonly adopted for operational control and data processing in space missions. To overcome the limitations of traditional radiation-hardened or fully commercial design approaches, a reconfigurable-system-on-chip (RSoC) solution based on state-of-the-art FPGA is introduced. The flexibility and reliability of this approach are outlined, and the requirements for an enhanced RSoC design with in-flight reconfigurability for space applications are presented. This design has been demonstrated as an on-board computer prototype, providing an in-flight reconfigurable DPU design approach using integrated hardwired processors.
