An indoor positioning system( IPS) is designed to realize positioning and tracking of mobile targets,by taking advantages of both the visible light communication( VLC) and inertial measurement unit( IMU). The platform...An indoor positioning system( IPS) is designed to realize positioning and tracking of mobile targets,by taking advantages of both the visible light communication( VLC) and inertial measurement unit( IMU). The platform of the IPS is designed,which consists of the light-emitting diode( LED)based transmitter,the receiver and the positioning server. To reduce the impact caused by measurement errors,both inertial sensing data and the received signal strength( RSS) from the VLC are calibrated. Then,a practical propagation model is established to obtain the distance between the transmitter and the receiver from the RSS measurements. Furthermore,a hybrid positioning algorithm is proposed by using the adaptive Kalman filter( AKF) and the weighted least squares( WLS)trilateration to estimate the positions of the mobile targets.Experimental results show that the developed IPS using the proposed hybrid positioning algorithm can extend the localization area of VLC,mitigate the IMU drifts and improve the positioning accuracy of mobile targets.展开更多
The APCDDI (adenomatosis polyposis coli down-regulated 1) gene is an inhibitor of the Wnt signaling pathway, and a rare mutation of this gene has been associated with hereditary hypotrichosis simplex. In this study,...The APCDDI (adenomatosis polyposis coli down-regulated 1) gene is an inhibitor of the Wnt signaling pathway, and a rare mutation of this gene has been associated with hereditary hypotrichosis simplex. In this study, the authors aimed to investigate whether common APCDD1 gene polymorphisms contribute to the development of androgenic alopecia. Patients (n = 210) with androgenic alopecia and 98 controls were investigated. SNPs (Single nucleotide polymorphisms) in the coding region of the gene were sequenced. A significant difference in genotype distribution was found for the c. 1781C/T, p.L476L SNP (rs3185480) of the APCDD1 gene. This SNP is located in exon 5 and is associated with a 3.5- and a 2.8-fold increase in risk for the development of androgenic alopecia for homozygote (CI 0.933-13.125; nominal regression P = 0.063) and heterozygote (CI 1.086-7.217; nominal regression P = 0.033) carriers, respectively. These data suggest that the rs3185480 polymorphism contributes to the development of androgenic alopecia. Protein expression experiments revealed that the polymorphism is associated with reduced APCDDI protein abundance. This reduction is likely due to altered codon usage for leucine from a preferred codon (CTC) to a rare codon (CTT), which might influence translation efficiency and, thus, APCDDI protein level.展开更多
Operating principle of water three-way valve with high flow for individual hydraulic prop in coal was presented in this paper, its strict and precise mathematical model was established, its flow field was simulated nu...Operating principle of water three-way valve with high flow for individual hydraulic prop in coal was presented in this paper, its strict and precise mathematical model was established, its flow field was simulated numerically by software Fluent, and its dynamic characteristics were analyzed during the work process such as raising leg, loading and overflow, the influence of the related parameters on high-flow water three-way valve was determined. The results as follows: during the raising leg stage and early raising leg stage, when the damping ratio increases, the overshoot of system decreases and the setting time reduces, and the dynamic response performance has a significant improvement. During the loading stage and the overflow stage, the pressure in plunger chamber of single hydraulic prop, the output flow and the displacement of the high-flow water three-way valve decrease with the decreasing of the external load. The spring stiffness of the safety valve directs the flow and the spool's displacement of the safety valve, and it can be used to control the high-flow three-way valve's sensitivity.展开更多
Here we introduce generalized momentum and coordinate to transform seismic wave displacement equations into Hamiltonian system.We define the Lie operators associated with kinetic and potential energy,and construct a n...Here we introduce generalized momentum and coordinate to transform seismic wave displacement equations into Hamiltonian system.We define the Lie operators associated with kinetic and potential energy,and construct a new kind of second order symplectic scheme,which is extremely suitable for high efficient and long-term seismic wave simulations.Three sets of optimal coefficients are obtained based on the principle of minimum truncation error.We investigate the stability conditions for elastic wave simulation in homogeneous media.These newly developed symplectic schemes are compared with common symplectic schemes to verify the high precision and efficiency in theory and numerical experiments.One of the schemes presented here is compared with the classical Newmark algorithm and third order symplectic scheme to test the long-term computational ability.The scheme gets the same synthetic surface seismic records and single channel record as third order symplectic scheme in the seismic modeling in the heterogeneous model.展开更多
This paper presents a unified bination algorithms (such as FrankWolfe problems. Global convergence results are framework of the nonmonotone convex comAlgorithm) for solving the traffic assignment established under m...This paper presents a unified bination algorithms (such as FrankWolfe problems. Global convergence results are framework of the nonmonotone convex comAlgorithm) for solving the traffic assignment established under mild conditions. The line search procedure used in our algorithm includes the nonmonotone Armijo rule, the non- monotone Goldstein rule and the nonmonotone Wolfe rule as special cases. So, the new algorithm can be viewed as a generalization of the regular convex combination algorithm.展开更多
For a closed orientable surface Sg of genus not smaller than 2,C(Sg) is the curve complex on S g whose vertices consist of the isotopy classes of nontrivial circles on Sg. It has been showed that any two vertices in C...For a closed orientable surface Sg of genus not smaller than 2,C(Sg) is the curve complex on S g whose vertices consist of the isotopy classes of nontrivial circles on Sg. It has been showed that any two vertices in C(Sg) can be connected by an edge path,and C(Sg) has an infinite diameter. We show that for 0 ≤i≤3g-5,two i-simplices can be connected by an(i +1)-path in C(Sg),and the diameter of C(Sg) under such a distance is infinite.展开更多
基金The National Natural Science Foundation of China(No.61741102,61471164,61601122)the Fundamental Research Funds for the Central Universities(No.SJLX_160040)
文摘An indoor positioning system( IPS) is designed to realize positioning and tracking of mobile targets,by taking advantages of both the visible light communication( VLC) and inertial measurement unit( IMU). The platform of the IPS is designed,which consists of the light-emitting diode( LED)based transmitter,the receiver and the positioning server. To reduce the impact caused by measurement errors,both inertial sensing data and the received signal strength( RSS) from the VLC are calibrated. Then,a practical propagation model is established to obtain the distance between the transmitter and the receiver from the RSS measurements. Furthermore,a hybrid positioning algorithm is proposed by using the adaptive Kalman filter( AKF) and the weighted least squares( WLS)trilateration to estimate the positions of the mobile targets.Experimental results show that the developed IPS using the proposed hybrid positioning algorithm can extend the localization area of VLC,mitigate the IMU drifts and improve the positioning accuracy of mobile targets.
文摘The APCDDI (adenomatosis polyposis coli down-regulated 1) gene is an inhibitor of the Wnt signaling pathway, and a rare mutation of this gene has been associated with hereditary hypotrichosis simplex. In this study, the authors aimed to investigate whether common APCDD1 gene polymorphisms contribute to the development of androgenic alopecia. Patients (n = 210) with androgenic alopecia and 98 controls were investigated. SNPs (Single nucleotide polymorphisms) in the coding region of the gene were sequenced. A significant difference in genotype distribution was found for the c. 1781C/T, p.L476L SNP (rs3185480) of the APCDD1 gene. This SNP is located in exon 5 and is associated with a 3.5- and a 2.8-fold increase in risk for the development of androgenic alopecia for homozygote (CI 0.933-13.125; nominal regression P = 0.063) and heterozygote (CI 1.086-7.217; nominal regression P = 0.033) carriers, respectively. These data suggest that the rs3185480 polymorphism contributes to the development of androgenic alopecia. Protein expression experiments revealed that the polymorphism is associated with reduced APCDDI protein abundance. This reduction is likely due to altered codon usage for leucine from a preferred codon (CTC) to a rare codon (CTT), which might influence translation efficiency and, thus, APCDDI protein level.
基金Supported by the National Natural Science Foundation of China (51075001) the Nature Science Research Project of Anhui Province (KJ2009A020)
文摘Operating principle of water three-way valve with high flow for individual hydraulic prop in coal was presented in this paper, its strict and precise mathematical model was established, its flow field was simulated numerically by software Fluent, and its dynamic characteristics were analyzed during the work process such as raising leg, loading and overflow, the influence of the related parameters on high-flow water three-way valve was determined. The results as follows: during the raising leg stage and early raising leg stage, when the damping ratio increases, the overshoot of system decreases and the setting time reduces, and the dynamic response performance has a significant improvement. During the loading stage and the overflow stage, the pressure in plunger chamber of single hydraulic prop, the output flow and the displacement of the high-flow water three-way valve decrease with the decreasing of the external load. The spring stiffness of the safety valve directs the flow and the spool's displacement of the safety valve, and it can be used to control the high-flow three-way valve's sensitivity.
基金financially supported by the National Natural Science Foundation of China(Grant Nos.41174047,40874024&41204041)
文摘Here we introduce generalized momentum and coordinate to transform seismic wave displacement equations into Hamiltonian system.We define the Lie operators associated with kinetic and potential energy,and construct a new kind of second order symplectic scheme,which is extremely suitable for high efficient and long-term seismic wave simulations.Three sets of optimal coefficients are obtained based on the principle of minimum truncation error.We investigate the stability conditions for elastic wave simulation in homogeneous media.These newly developed symplectic schemes are compared with common symplectic schemes to verify the high precision and efficiency in theory and numerical experiments.One of the schemes presented here is compared with the classical Newmark algorithm and third order symplectic scheme to test the long-term computational ability.The scheme gets the same synthetic surface seismic records and single channel record as third order symplectic scheme in the seismic modeling in the heterogeneous model.
基金This research is partly supported by National Outstanding Young Investigator Grant(70225005) of National Natural Science Foundation of China and the Project(70471088) of National Natural Science Foundation of China.
文摘This paper presents a unified bination algorithms (such as FrankWolfe problems. Global convergence results are framework of the nonmonotone convex comAlgorithm) for solving the traffic assignment established under mild conditions. The line search procedure used in our algorithm includes the nonmonotone Armijo rule, the non- monotone Goldstein rule and the nonmonotone Wolfe rule as special cases. So, the new algorithm can be viewed as a generalization of the regular convex combination algorithm.
基金supported by National Natural Science Foundation of China(Grant Nos.10931005 and 11101058)the National Science Foundation for Post-doctoral Scientists of China(Grant No.2011M500049)
文摘For a closed orientable surface Sg of genus not smaller than 2,C(Sg) is the curve complex on S g whose vertices consist of the isotopy classes of nontrivial circles on Sg. It has been showed that any two vertices in C(Sg) can be connected by an edge path,and C(Sg) has an infinite diameter. We show that for 0 ≤i≤3g-5,two i-simplices can be connected by an(i +1)-path in C(Sg),and the diameter of C(Sg) under such a distance is infinite.