The ability of vitamin E to prevent or treat experimental lead intoxication was investigatedin rats.Lead ingestion(10 mg/kg,lead as lead acetate,orally fbr 6 weeks)significantly inhibitedthe activity of blood δ-amino...The ability of vitamin E to prevent or treat experimental lead intoxication was investigatedin rats.Lead ingestion(10 mg/kg,lead as lead acetate,orally fbr 6 weeks)significantly inhibitedthe activity of blood δ-aminolevulinic acid dehydratase(ALAD),reduced the brain dopamine(DA)contents,enhanced the blood zinc protoporphyrin,and enhanced the urinary excretion ofδ-aminolevulinic acid(ALA).Lead exposure also elevated brain norepinephrine,homovanillicacid,and 5-hydroxyindole acetic acid(5-HIAA)levels and concentration of lead in blood andtissue.Simultaneous supplementation of vitamin E along with lead significantly reduced theinhibition of blood ALAD activity,brain DA and 5-HIAA levels,and elevation of urinary ALAexcretion.Blood and liver lead concentrations were also significantly reduced by simultaneoussupplementation with vitamin E.Postlead exposure treatment with vitamin E was ineffective inreducing the lead-induced effects,except that the inhibition of blood ALAD activity was slightlyreduced.The present results suggest that vitamin E given simultaneously with lead is effectivein reducing the severity of lead intoxication.1989 Academic Press.Inc.展开更多
Let D={z:|z|【1}be the unit disk in the finite complex plane C,and A the set of func-tions analytic on D.Bergman space A<sup>1</sup>={f:f∈A,‖f‖<sub>1</sub>=∫<sub>D</sub>|f|dm【...Let D={z:|z|【1}be the unit disk in the finite complex plane C,and A the set of func-tions analytic on D.Bergman space A<sup>1</sup>={f:f∈A,‖f‖<sub>1</sub>=∫<sub>D</sub>|f|dm【∞}.A new atomic“de-composition”for A<sup>1</sup> is obtained,and more the interpolating problem is solvable in A<sup>1</sup> undercertain conditions.展开更多
文摘The ability of vitamin E to prevent or treat experimental lead intoxication was investigatedin rats.Lead ingestion(10 mg/kg,lead as lead acetate,orally fbr 6 weeks)significantly inhibitedthe activity of blood δ-aminolevulinic acid dehydratase(ALAD),reduced the brain dopamine(DA)contents,enhanced the blood zinc protoporphyrin,and enhanced the urinary excretion ofδ-aminolevulinic acid(ALA).Lead exposure also elevated brain norepinephrine,homovanillicacid,and 5-hydroxyindole acetic acid(5-HIAA)levels and concentration of lead in blood andtissue.Simultaneous supplementation of vitamin E along with lead significantly reduced theinhibition of blood ALAD activity,brain DA and 5-HIAA levels,and elevation of urinary ALAexcretion.Blood and liver lead concentrations were also significantly reduced by simultaneoussupplementation with vitamin E.Postlead exposure treatment with vitamin E was ineffective inreducing the lead-induced effects,except that the inhibition of blood ALAD activity was slightlyreduced.The present results suggest that vitamin E given simultaneously with lead is effectivein reducing the severity of lead intoxication.1989 Academic Press.Inc.
基金Supported by Doctoral Program Foundation of Institute of Higher Education.
文摘Let D={z:|z|【1}be the unit disk in the finite complex plane C,and A the set of func-tions analytic on D.Bergman space A<sup>1</sup>={f:f∈A,‖f‖<sub>1</sub>=∫<sub>D</sub>|f|dm【∞}.A new atomic“de-composition”for A<sup>1</sup> is obtained,and more the interpolating problem is solvable in A<sup>1</sup> undercertain conditions.
