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肛门括约肌肌电图卫星电位对多系统萎缩的诊断意义 被引量:2
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作者 崔博 李存江 +6 位作者 卫华 王德泉 任宇航 林仲希 张跃馨 任付璐 赵筱玲 《北京医学》 CAS 2021年第2期99-102,共4页
目的评价肛门括约肌肌电图(external anal sphincter electromyography,EAS-EMG)卫星电位(satellite poten-tial,SP)对于多系统萎缩(multiple system atrophy,MSA)诊断的意义。方法选取2017年6月至2018年6月首都医科大学宣武医院收治的... 目的评价肛门括约肌肌电图(external anal sphincter electromyography,EAS-EMG)卫星电位(satellite poten-tial,SP)对于多系统萎缩(multiple system atrophy,MSA)诊断的意义。方法选取2017年6月至2018年6月首都医科大学宣武医院收治的MSA患者进行EAS-EMG检查,对同期就诊的帕金森病(Parkinson’s disease,PD)患者及招募的健康受试者(healthy control,HC)均进行该检查,获得运动电位(motor unit potential,MUP)各项参数并分析SP形态学参数。结果分别入组30例MSA患者、15例PD患者及20例HC,MSA组的MUP平均时限为(11.8±1.5)ms,比PD组的(10.0±0.6)ms和HC组的(10.1±0.9)ms显著延长,差异有统计学意义(P<0.001)。以SP与主波间距≥1 ms等电位线为标准,MSA组SP出现率为(9.2±7.9)%,显著高于PD的(1.4±2.9)%及HC组的(2.2±2.7)%,差异有统计学意义(P<0.001)。结论SP出现率是MSA电生理诊断的重要参数,但其敏感性与特异性仍有待进一步研究。 展开更多
关键词 肛门括约肌肌电图 卫星电位 多系统萎缩
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动电容式电位监测器原理和结构参数设计
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作者 石红 田立成 +1 位作者 杨生胜 薛玉雄 《真空》 CAS 2013年第5期31-34,共4页
航天器表面充电到高静电位会导致静电放电(ESD),从而影响甚至破坏卫星电子器件。静电放电事件大多与各种表面材料之间的差异带电有关,因此研究不同表面材料在空间的充电电位对于控制航天器表面静电放电事件至关重要。本文介绍了用于测... 航天器表面充电到高静电位会导致静电放电(ESD),从而影响甚至破坏卫星电子器件。静电放电事件大多与各种表面材料之间的差异带电有关,因此研究不同表面材料在空间的充电电位对于控制航天器表面静电放电事件至关重要。本文介绍了用于测量表面电位的静电感应式电位监测器的工作原理,并且对探头部分设计参数的选取进行了数值模拟计算研究,用于设计参数的选取和优化。 展开更多
关键词 卫星表面电位监测器 振动电容式 充放电效应
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多系统萎缩自主神经功能障碍研究的新进展 被引量:7
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作者 朱静 李胜 《临床神经病学杂志》 CAS 北大核心 2016年第4期315-317,共3页
多系统萎缩(MSA)是一种成年后发病、散发、快速进展的神经系统变性疾病,临床特征为帕金森综合征,以及小脑、自主神经、锥体束等功能障碍的不同组合[1-3]。自主神经功能障碍是MSA的重要特征,维持心血管、呼吸、泌尿生殖、胃肠和排汗等... 多系统萎缩(MSA)是一种成年后发病、散发、快速进展的神经系统变性疾病,临床特征为帕金森综合征,以及小脑、自主神经、锥体束等功能障碍的不同组合[1-3]。自主神经功能障碍是MSA的重要特征,维持心血管、呼吸、泌尿生殖、胃肠和排汗等功能的中枢和外周自主神经均可受累,且相关症状常可先于运动症状出现;早期自主神经功能衰竭成为疾病快速进展和不良预后的独立预测因素。因此, 展开更多
关键词 多系统萎缩 运动症状 帕金森综合征 胃肠和 卫星电位 功能障碍 泌尿系统症状 神经系统变性病 神经功能异常 锥体束
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Evaluation of Barley Genotypes for Resistance to Pyrenophora Teres Using Molecular Markers
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作者 Leona Leisova-Svobodova Lenka Stemberkova +1 位作者 Martina Hanusova Ladislav Kuaera 《Journal of Life Sciences》 2011年第7期497-502,共6页
Net blotch disease caused by the fungus Pyrenophora teres belongs to the complex of leaf blotch diseases that decrease the yield and the quality of barley (Hordeum vulgate L.). This study deals with the use of micro... Net blotch disease caused by the fungus Pyrenophora teres belongs to the complex of leaf blotch diseases that decrease the yield and the quality of barley (Hordeum vulgate L.). This study deals with the use of microsatellites localized nearby the quantitative trait loci, associated with the resistance to P. teres to screen barley lines and varieties that could be introduced into a net blotch resistance breeding program. Thirty-five barley microsatellite loci and 65 barley genotypes, 265 alleles were detected. The number of alleles per locus ranged from 2 to 26. The arrangement of genotypes into clusters based on microsatellite data does not correspond to their resistance level to P. teres even though chosen microsatellite markers have been localized nearby QTLs associated with the resistance to P. teres. 展开更多
关键词 BARLEY microsatellites net blotch resistance.
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Personal continuous route pattern mining 被引量:1
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作者 Qian YE Ling CHEN Gen-cai CHEN 《Journal of Zhejiang University-Science A(Applied Physics & Engineering)》 SCIE EI CAS CSCD 2009年第2期221-231,共11页
In the daily life,people often repeat regular routes in certain periods. In this paper,a mining system is developed to find the continuous route patterns of personal past trips. In order to count the diversity of pers... In the daily life,people often repeat regular routes in certain periods. In this paper,a mining system is developed to find the continuous route patterns of personal past trips. In order to count the diversity of personal moving status,the mining system employs the adaptive GPS data recording and five data filters to guarantee the clean trips data. The mining system uses a client/server architecture to protect personal privacy and to reduce the computational load. The server conducts the main mining procedure but with insufficient information to recover real personal routes. In order to improve the scalability of sequential pattern mining,a novel pattern mining algorithm,continuous route pattern mining(CRPM),is proposed. This algorithm can tolerate the different disturbances in real routes and extract the frequent patterns. Experimental results based on nine persons' trips show that CRPM can extract more than two times longer route patterns than the traditional route pattern mining algorithms. 展开更多
关键词 Data mining Route pattern GPS Mobile phone
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Global modeling 2^(nd)-order ionospheric delay and its effects on GNSS precise positioning 被引量:5
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作者 ZHANG HongPing LV HaiXia +1 位作者 LI Min SHI Chuang 《Science China(Physics,Mechanics & Astronomy)》 SCIE EI CAS 2011年第6期1059-1067,共9页
Ionospheric delay is one of the major error sources in GNSS navigation and positioning.Nowadays,the dual-frequency technique is the most widely used in ionospheric refraction correction.However,dual-frequency measurem... Ionospheric delay is one of the major error sources in GNSS navigation and positioning.Nowadays,the dual-frequency technique is the most widely used in ionospheric refraction correction.However,dual-frequency measurements can only eliminate the first-order term of ionospheric delay,while the effect of the second-order term on GNSS observations may be several centimeters.In this paper,two models,the International Reference Ionosphere (IRI) 2007 and International Geomagnetic Reference Field (IGRF) 11 are used to estimate the second-order term through the integral calculation method.Besides,the simplified single layer ionosphere model in a dipole moment approximation for the earth magnetic field is used.Since the traditional integral calculation method requires large calculation load and takes much time,it is not convenient for practical use.Additionally,although the simplified single layer ionosphere model is simple to implement,it results in larger errors.In this study,second-order term ionospheric correction formula proposed by Hoque (2007) is improved for estimating the second-order term at a global scale.Thus,it is more practicable to estimate the second-order term.More importantly,its results have a higher precision of the sub-millimeter level for a global scale in normal conditions.Compared with Hoque's original regional correction model,which calculates coefficients through polynomial fitting of elevation and latitudes,this study proposes a piece-wise look-up table and interpolation technique to modify Hoque model.Through utilizing a table file,the modified Hoque model can be conveniently implemented in an engineering software package,like as PANDA in this study.Through applying the proposed scheme for the second-order ionospheric correction into GNSS precise positioning in both PPP daily and epoch solutions,the results have shown south-shift characteristics in daily solution at a global scale and periodic change with VTEC daily variation in epoch positioning solution. 展开更多
关键词 ionospheric delay second-order ionospheric correction GNSS precise positioning
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