Moxibustion down-regulates colonic epithelial cell apoptosis and repairs tight junctions in rats with Crohn's disease

AIM: To investigate the effects of moxibustion on down-regulation of the colonic epithelial cell apoptosis and repair of the tight junctions in rats with Crohn's disease (CD). METHODS: Sixty male Sprague-Dawley rats were randomly divided into a normal control (NC) group, a model control (MC) group, an herbs-partitioned moxibustion (HPM) group, a mild-warm moxibustion (MWM) group and a salicylazosulphapyridine (SASP) group, with 12 rats in each group. The CD model rats were treated with trinitrobenzene sulphonic acid to induce intestinal inflammation. The rats in the HPM and MWM groups were treated at the Tianshu (ST25) and Qihai (CV6) acupoints once daily for 14 d, and the SASP group was fed SASP twice daily for 14 d. No additional treatment was given to the MC and NC groups. Themicrostructure of the colonic epithelium was observed under a transmission electron microscope, the transepithelial resistance was measured using a shortcircuit current, colonic epithelial cell apoptosis was determined by terminal deoxynucleotidyl transferasemediated dUTP-biotin nick end labelling assay, and the expression of occludin, claudin-1 and zonula occludens-l (ZO-1) in the colonic epithelial junction was determined by Western blotting and immunofluorescence staining. RESULTS: Compared with the MC group, the microstructure of the colonic epithelial barrier was signifi-cantly improved in rats treated with HPM, MWM or SASP, meanwhile, the current flow was reduced signifi-cantly, with values of 168.20 ± 6.14 vs 99.70 ± 3.13, 99.10 ± 4.28 and 120.30 ± 3.65 mA, respectively (P = 0.001). However, the HPM and MWM groups had higher current flow rates than the SASP group (99.70 ± 3.13, 99.10 ± 4.28 vs 120.30 ± 3.65 mA, P = 0.001). The number of the apoptotic colonic epithelial cells in HPM, MWM and SASP groups was largely reduced (61.5 ± 16.91 vs 15.5 ± 8.89, 14.8 ± 6.27 and 24.7 ± 9.68, respectively (P = 0.001); and the expression of occlu- din, claudin-1 and ZO-1 in the MWM and HPM groups was signifi cantly enhanced (0.48 ± 0.10, 0.64 ± 0.09 vs 0.18 ± 0.05 for occludin, 0.12 ± 0.02, 0.17 ± 0.03 vs 0.05 ± 0.01 for claudin-1, and 0.08 ± 0.01, 0.11 ± 0.01 vs 0.02 ± 0.01 for ZO-1). And in SASP group, the expression of occludin and ZO-1 was also signifi cantly increased (0.27 ± 0.04 vs 0.18 ± 0.05 for occludin and 0.05 ± 0.01 vs 0.02 ± 0.01 for ZO-1), but there was no significant difference for claudin-1. The HPM and MWM groups had higher expression of occludin, claudin-1 and ZO-1 than the SASP group. CONCLUSION: HPM and MWM treatment can down-regulate apoptosis of colonic epithelial cells, repair tight junctions and enhance colonic epithelial barrier function in rats with CD.

Seasonal variability of salinity budget and water exchange in the northern Indian Ocean from HYCOM assimilation

Based on HYbrid Coordinate Ocean Model (HYCOM) assimilation and observations, we analyzed seasonal variability of the salinity budget in the southeastern Arabian Sea (AS) and the southern part of the Bay of Bengal (BOB), as well as water exchange between the two basins. Results show that fresh water flux cannot explain salinity changes in salinity budget of both regions. Oceanic advection decreases salinity in the southeastern AS during the winter monsoon season and increases salinity in the southern BOB during the summer monsoon season. In winter, the Northeast Monsoon Current (NMC) carries fresher water from the BOB westward into the southern AS; this westward advection is confined to 4°-6°N and the upper 180 m south of the Indian peninsula. Part of the less saline water then turns northward, decreasing salinity in the southeastern AS. In summer, the Southwest Monsoon Current (SMC) advects high-salinity water from the AS eastward into the BOB, increasing salinity along its path. This eastward advection of high-salinity water south of the India Peninsula extends southward to 2°N, and the layer becomes shallower than in winter. In addition to the monsoon current, the salinity difference between the two basins is important for salinity advection.

Petrographic characterization and evolution of the Karharbari coals, Talcher Coalfield, Orissa, India

In the present study an attempt has been made to carry out the detailed petrographic characterization of the Karharbari coals of Talcher coalfield and to reconstruct the paleoenvironment conditions of coal formation using macerals and microlithtotypes as a tool. For these purposes a large number of samples were collected following the pillar sampling method and were subjected to detailed petrographic study. The petrographic observation shows that these coals are vitrinite rich followed by the liptinite and inertinite group of macerals. On microlithotype scale, these coals shows the dominance of the vitrite followed by clarite, vitrinertite and inertite. The concentration of liptite, clarodurite, duroclarite and vitriner- toliptite are insignificant. The vitrinite reflectance ranks the Karharbari coal as high volatile bituminous ＇C＇ to high volatile ＇B＇ bituminous. Coal petrography based depositional models suggest peat accumulation in forested telmatic swamp. Moreover, during the time of their evolution, there were alternate phases of oxic and anoxic moor conditions with good tissue preservation.

Thermal contrast between the Tibetan Plateau and tropical Indian Ocean and its relationship to the South Asian summer monsoon

The land-sea thermal contrast is an important driver for monsoon interannual variability and the monsoon onset.The thermal contrast between the Tibetan Plateau and the tropical Indian Ocean at the mid-upper troposphere is proposed as a thermal contrast index(TCI)for South Asian monsoon.The authors investigate the TCI associated with South Asian summer monsoon(SASM)intensity and SASM onset.It is observed that the TCI considering the Tibetan Plateau and tropical Indian Ocean demonstrates a stronger and closer correlation with SASM intensity(0.87)than either the Tibetan Plateau(0.42)or tropical Indian Ocean(-0.60)singly.It is implied that the TCI could preferably represent the impact of land-sea thermal condition on SASM activity.Further analysis reveals that the evolution of TCI is related to the SASM onset.The TCI is almost always larger in early onset years than it is in late onset years during the period before SASM onset.In addition,the change of the pentad-by-pentad increment of TCI leads the SASM variation.The correlation coefficient between the TCI increment and SASM index reaches a maximum when the TCI increment leads by 15 pentads.The results of this study show that the TCI plays an important role in SASM activities and is a potential indicator for SASM onset forecasting.

Living in a High Mountain Border Region:the Case of the'Bhotiyas'of the Indo-Chinese Border Region

This article introduces one of South Asia's most important border regions into academic discourse, namely, the Central Himalayan mountain rim separating India and the Tibetan Autonomous Region (People's Republic of China). What makes this border region so interesting is a tangled interplay of changing environmental, cultural, and political forms to which the local populations constantly have to adapt in order to make a living there. We focused on the so-called 'Bhotiyas' of Uttarakhand, former trans-Himalayan traders whose ethnicity and livelihood was traditionally associated with the Indo-Chinese border that was sealed as a result of the India-China war in 1962. Drawing on the work of borderland scholarship, we identified the key processes and developments that changed the perspective of this area. Competing political aspirations as well as the 'Bhotiyas' countervailing strategies were considered equally important for understanding local livelihoods and identities within the dynamics of a 'high mountain border region'. Through an exemplary analysis of historical differences of power in one 'Bhotiya' valley, we further explored the ways in which shifting socio-spatial constellations are creatively re-interpreted by the borderlanders.

Comparing the model forms estimating generalised diameter-height re-lationships in Tecomella undulata plantations in hot arid region of India

Four generalised diameter-height equations were developed and compared for pure and even-aged stands of Tecomella undulata in hot arid region of Rajasthan State in India. The data used to fit the equations consisted of 1 540 diameter-height observations collected from the plots laid out in uniformly stocked stands of varying age and density. The performance of four equations was tested by non-linear least squares regression and evaluated using different statistical criteria. Finally, these equations, with the same values of coefficients ob- tained during the fitting phase, were validated by an independent data set consisting of 854 diameter-height observations. Overall, equation （4） （Hui and Gadow function） was found to perform best for both the fitting data set as well as validation data set.

Availability and Use of Willow Species in Representative Cold Desert Areas of Northwestern Himalaya,India

Willow species （Salix fragilis L. and S. alba L.） are important elements of cold desert agroforestry systems in the Lahaul valley, north- western Himalaya. Their ability to grow through shoot-cuttings plantations under extreme and xeric climatic conditions of cold deserts, makes them ecologically suited and socially accepted for forestry programmes. Willow species in cold deserts may combat desertification and can thrive well in these areas as compared to any other species. Salixfragilis L. and S. alba L. are under cultivation in the Lahaul valley. However, S. fragilis is widely cultivated under the agroforestry and plantation forestry systems. In the Lahaul valley, willow species are used as subsistence resources and for socio-religious purposes. The present study was carried out to examine the vegetation analysis, density, diversity and distribution of willow species, present status and potential willow plantation sites and uses. The results of present study revealed that a higher species density was recorded at middle altitude villages （Jahlma-3,ooo m asl and Hinsa-2,7oo m asl）, except, a higher density of S. fragilis was at Khoksar （3,200 m asl） in plantation forestry on south-facing slopes. In forests, S. fragilis was planted mainly along the water channels, resulted a low density. The shrubby willow species occurred naturally in the entire Lahaul valley up to an altitude of 3,850 m asl. 81% of households felt the scarcity of willow trees, whereas, 19% of households were satisfied with the willow trees they owned. The majority of willow species were planted in middle altitudes on privately owned irrigated lands. It was rated most potential prospective willow planting siteby the farmers. Small size of land-holdings was one of the main constraints for establishing a large number of willow plantations. Commercial aspects of willow species need to be investigated to encourage the farmers to plant more willows further.

Roll-to-roll imprint for high precision grating manufacturing

In this paper,a novel roll-to-roll imprint process is proposed to fabricate gratings in large area. The key challenges in roll-to-roll imprint process,such as the roller mold preparation,imprint system,misalignment of imprint roller and backup roller,and also the imprint pressure,are investigated. Various gratings with different periods and profiles are obtained by the roll-to-roll process. To calibrate the measuring ability of the self-made grating by imprint,a calibration system is built with a dual-frequency laser interferometer. By the calibration,the self-made gratings can achieve ±4μm accuracy in 45mm measuring distance.

Visual positioning of rectangular lead components based on Harris corners and Zernike moments

With the increasing necessities for reliable printed circuit board(PCB) product, there has been a considerable demand for high speed and high precision vision positioning system. To locate a rectangular lead component with high accuracy and reliability, a new visual positioning method was introduced. Considering the limitations of Ghosal sub-pixel edge detection algorithm, an improved algorithm was proposed, in which Harris corner features were used to coarsely detect the edge points and Zernike moments were adopted to accurately detect the edge points. Besides, two formulas were developed to determine the edge intersections whose sub-pixel coordinates were calculated with bilinear interpolation and conjugate gradient method. The last experimental results show that the proposed method can detect the deflection and offset, and the detection errors are less than 0.04° and 0.02 pixels.

Distribution of heavy metals during pyrolysis of waste printed circuit boards

The volatilization behavior of Cu, Pb, Sn, Sb, Ni, Zn, Mn, Co, Cr, Cd during pyrolysis of waste printed circuit boards was investigated in a bench-scale fixed-bed pyrolysis system. It was found that volatility of heavy metals increases with operating temperature elevating, and bromine and vacuum have an obvious promoting effect on volatility of most of heavy metals. Over 99% weight of Cu and Ni are still remained in solid residue after pyrolysis, about 20% weight of Sb, Zn and Cd are transfered into liquid and gas during a pyrolysis process at 600 ℃, volatilization fractions of Pb, Sn, Mn, Co, Cr are less than 10% at the same conditions. The contents of heavy metals in liquid and gas products depend on not only volatility of metals, but also their initial contents in printed circuit boards, pyrolysis liquid and gas are primarily contaminated by Cu, Pb, Sn, Sb and Zn, their contents in liquid vary from 10^2 to 10^3 pg/mL, Mn, Co, Cr, Cd were detected only at very low level, less than 10 μg/mL.

Molecularly Imprinted Polymers for Selective Extraction of Crystal Violet from Natural Seawater coupled with HighPerformance Liquid Chromatographic Determination

Molecularly imprinted polymers （MIPs） were prepared by the bulk polymerization using crystal violet as the template molecule, and the methacrylic acid and ethylene glycol dimetheacrylate as functional monomer and cross-linker, respectively. Sys- tematic investigations of synthetic conditions were conducted. The surface morphology and recognition mechanism of the obtained polymers were studied using scanning electron microscope and spectrophotometric analysis. MIPs showed high atTmity to template molecule and were successfully applied as special solid-phase extraction sorbent for selective extraction of crystal violet from natural seawater. An off-line molecularly imprinted solid-phase extraction （MISPE） method followed by high-performance liquid chroma- tography with diodearray detection for the analysis of crystal violet was also established. MISPE columns have good recoveries for crystal violet standard solutions and good linearity was obtained over the concentration range of 0-200 ~tg L-1 （R2 〉 0.99）. Finally, two natural seawater samples were investigated. The recoveries of spiked seawater on the MISPE columns were from 44.47% to 62.34%, the relative standard deviation （n=3） being in the range of 2.89%-5.96%.

Coexistence of hyperlipidemia and acute cerebral ischemia/reperfusion induces severe liver damage in a rat model

AIM:To investigate the correlation of hyperlipemia(HL) and acute cerebral ischemia/reperfusion(I/R) injury on liver damage and its mechanism.METHODS:Rats were divided into 4 groups:control,HL,I/R and HL+I/R.After the induction of HL via a high-fat diet for 18 wk,middle cerebral artery occlusion was followed by 24 h of reperfusion to capture I/R.Serum alanine transaminase(ALT) and aspartate aminotransferase(AST) were analyzed as part of liver function tests and liver damage was further assessed by histological examination.Hepatocyte apoptosis was evaluated by terminal deoxynucleotidyl transferase dUTP nick-end labeling(TUNEL) assay.The expression of genes related to apoptosis(caspase-3,bcl-2) was assayed by immunohistochemistry and Western blotting.Serum tumor necrosis factor-(TNF-),interleukin-1(IL-1) and liver mitochondrial superoxide dismutase(SOD),glutathione peroxidase(GSH-Px),malondialdehyde(MDA) and Ca 2+ levels were measured to determine inflammatory and oxidative/antioxidative status respectively.Microsomal hydroxylase activity of the cytochrome P450 2E1(CYP2E1)-containing enzyme was measured with aniline as the substrate,and CYP2E1 expression in the liver tissue and microsome was determined by immunohistochemistry and Western blotting respectively.RESULTS:HL alone induced by high-fat diet for 18 wk resulted in liver damage,indicated by histopathological analysis,and a considerable increase in serum ALT(25.13 ± 16.90 vs 9.56 ± 1.99,P < 0.01) and AST levels(18.01 ± 10.00 vs 11.33 ± 4.17,P < 0.05) compared with control.Moreover,HL alone induced hepatocyte apoptosis,which was determined by increased TUNEL-positive cells(4.47 ± 0.45 vs 1.5 ± 0.22,P < 0.01),higher caspase-3 and lower bcl-2 expression.Interestingly,compared with those in control,HL or I/R groups,massive increases of serum ALT(93.62 ± 24.00 vs 9.56 ± 1.99,25.13 ± 16.90 or 12.93 ± 6.14,P < 0.01) and AST(82.32 ± 26.92 vs 11.33 ± 4.17,18.01 ± 10.00 or 14.00 ± 6.19,P < 0.01) levels in HL+I/R group were observed suggesting severe liver damage,which was confirmed by liver histology.In addition,HL combined with I/R also caused significantly increased hepatocyte apoptosis,as evidenced by increased TUNEL-positive cells(6.20 ± 0.29 vs 1.5 ± 0.22,4.47 ± 0.45 or 1.97 ± 0.47,P < 0.01),elevated expression of caspase-3 and lower expression of bcl-2.Furthermore,when compared to HL or I/R alone,HL plus I/R enhanced serum TNF-,IL-1,liver mitochondrial MDA and Ca 2+ levels,suppressed SOD and GSH-Px in liver mitochondria,and markedly up-regulated the activity(11.76 ± 2.36 vs 4.77 ± 2.31 or 3.11 ± 1.35,P < 0.01) and expression(3.24 ± 0.38 vs 1.98 ± 0.88 or 1.72 ± 0.58,P < 0.01) of CYP2E1 in liver.CONCLUSION:The coexistence of HL and acute cerebral I/R induces severe liver damage,suggesting that cerebral ischemic stroke would exaggerate the damage of liver caused by HL.This effect is possibly due to en-hanced CYP2E1 induction which further promotes oxidative damage,inflammation and hepatocyte apoptosis.

Physico-chemical and elemental investigation of aqueous leaching of high sulfur coal and mine overburden from Ledo coalfield of Northeast India

Acid mine drainage （AMD） is one of the major problems in high sulfur coal mining areas generating acidic water. The acidic mine water generated contain hazardous elements in varying concentrations. The Northeastern Indian coalfield produces considerable amounts of AMD. The AMD and metal leaching from coal and mine over burden （OB） are the two important naturally occurring processes. In order to know the AMD potential, the aqueous leaching experiment of a few coal and OB samples from the Ledo colliery of the Northeastern coalfield, Mergherita （India）, at different time periods （1, 3, 5, and 8 h） and at different temperatures （25, 45, 65, and 90℃） were performed in the laboratory. The physico- chemical analysis of the aqueous leachates shows the pH, electrical conductivity （EC）, and total dissolved solid （TDS） in the range of 1.62-3.52, 106-2006 μs/cm, and 106-1003 ppm for the raw coal samples respectively. The OB samples produced pH, EC, and TDS in the range of 3.68-6.92, 48.6-480 μs/cm, and 69.5-240 ppm respectively. From the study, it was revealed that the concentrations of major （Si, A1, K, Na, Fe, Ca, Mg）, minor （Mn） and trace/hazardous elements （As, Ba, Cd, Co, Cr, Cu, Hg, Ni, Pb, Se, Zn） considerably change with leaching time as well as with leaching temperature. Out of these elements As, Cd, Hg, Pb, Cr, and Se are of greater environmental importance. Alteration of the physico-chemical structure of the coal and OB samples resulting from leaching was also studied by field emission scanning electron microscope- energy-dispersive X-ray spectroscopy method. The release of the potentially hazardous elements from the raw coal and OB during leaching time periods to the leachates was detected by inductively coupled plasma-atomic emission spectroscopy and ion-chromatographic analyses. The major minerals found in coal and OB are quartz （SiO2）, pyrite （FeS2）, hematite, marcasite, and kaolinite. The association of different functional groups in minerals and their mode of association were studied by Fourier-transform infrared spectroscopy and X-ray diffraction analytical techniques. The present laboratory study will be useful in relating the characteristics of aqueous leaching from coal and mine OB with the natural weathering condition at the coal mine area.

Hydro-hypsometric analysis of tropical river basins,Southwest Coast of India using geospatial technology

The key aspect in planning and management of water resources is to analyze the runoff potential and erosion status of the river basin.For the detailed investigation of hydrological response freely available Cartosat-1(IRS-P5) data was used for the preparation of digital elevation model(DEM).The runoff potential and type of erosive process of 22 river basins originating in the global biodiversity hotspot of Western Ghats,was inferred through hypsometric analysis.Several parameters like Hypsometric integral(HI),maximum concavity(Eh),coordinates of slope inflection point(I) given by a* and h* and normalized height of hypsometric curve(h) were extracted from the hypsometric curves and used for understanding the hydrological responses.From the hypsometric curves,the landform evolution processes were inferred.Contribution of diffusive and fluvial processes in slope degradation of the river basins was understood.Basins with lesser area(<100 km^2) were found to have a positive correlation between hypsometric integral and basin area,whereas for large basins no such correlation exists.Based on the study,river basins can be prioritized for the appropriate conservation measures.

Vacuum pyrolysis of waste print circuit board

Waste print circuit board containing 11.38% Br was pyrolyzed in vacuum. Thermal stability of waste print circuit board was studied under vacuum condition by thermo-gravimetry(TG). Vacuum pyrolysis of WPCB was studied emphasizing on the kinetics of WPCB pyrolysis reactions. Based on the TG results, a kinetic model was pro- posed. Kinetic parameters were calculated for reaction with this model including all stages of decomposition. The average activation energy is 68 kJ/mol with reaction order 3. These findings provide new insights into the WPCB thermal decomposition and useful data for rational design and operation of pyrolysis.

Predicting Western Pacific Subtropical High Using a Combined Tropical Indian Ocean Sea Surface Temperature Forecast

Weather and climate in East China are closely related to the variability of the western Pacific subtropical high(WPSH), which is an important part of the Asian monsoon system. The WPSH prediction in spring and summer is a critical component of rainfall forecasting during the summer flood season in China. Although many attempts have been made to predict WPSH variability, its predictability remains limited in practice due to the complexity of the WPSH evolution. Many studies have indicated that the sea surface temperature(SST) over the tropical Indian Ocean has a significant effect on WPSH variability. In this paper, a statistical model is developed to forecast the monthly variation in the WPSH during the spring and summer seasons on the basis of its relationship with SST over the tropical Indian Ocean. The forecasted SST over the tropical Indian Ocean is the predictor in this model, which differs significantly from other WPSH prediction methods. A 26-year independent hindcast experiment from 1983 to 2008 is conducted and validated in which the WPSH prediction driven by the combined forecasted SST is compared with that driven by the persisted SST. Results indicate that the skill score of the WPSH prediction driven by the combined forecasted SST is substantial.

Foraging ecology of the globally threatened Nilgiri Wood Pigeon(Columba elphinstonii)in the Western Ghats,India

Foraging ecology of the globally endangered Nilgiri Wood Pigeon(Columba elphinstonii) was investigated in the Western Ghats,India,using faecal sampling and direct observations.The birds fed on fruits of 39 plant species,on seeds of 11 species,flowers and leaf buds of four species and a few ground invertebrates.Direct observations across seasons showed nine plant species were selected more often(47% of observations),with fruits of the members of the family Lauraceae the most preferred.Gleaning accounted for 76% of feeding methods throughout the year.Feeding was mainly from twigs at the edges on the upper and middle canopy(> 6 m).Frequency of feeding on fruits correlated significantly with fruit abundance,which depended on rainfall.The present study indicates that the pigeon requires a wide variety of diets from different forest environments.Conservation of this species depends on preserving all habitat types required to meet their resource needs throughout the year.

Study of front bumper process on the basis of hot stamping

The fitting method is used for obtaining the constitutive relation of ultra-high strength steel in this paper. At the same time, the forming limit of material is researched under different de/brmation conditions. Through experiments, the paper obtains stress-strain curve under different deformation temperatures and strain rates. On the basis of experimental data, the constitutive relation model is established which can reflect the de- fomlation capacity of ultra-high strength steel during process of hot stamping. Combining with finite element simulation results of hot stamping by the commercial software AUTOFORM, transfer path of load and matching law of strength, the paper determines the design criteria and forming process requirements of parts manufactured by hot stamping. Through setting different process parameters, such as punch velocity and friction coefficient, and blank shape, the paper finds that process parameters and blank shape have an essential effect on the quality of parts.

Evaluation of High-Resolution WRF Model Simulations of Surface Wind over the West Coast of India

This paper presents results from a statistical validation of the hindcasts of surface wind by a high-reso-ution-mesoscale atmospheric numerical model Advanced Research WRF （ARW3.3）, which is set up to force the operational coastal ocean forecast system at Indian Na- tional Centre for Ocean Information Services （INCOIS）. Evaluation is carried out based on comparisons of day-3 forecasts of surface wind with in situ and remote-sensing data. The results show that the model predicts the surface wind fields fairly accurately over the west coast of India, with high skill in predicting the surface wind during the pre-monsoon season. The model predicts the diurnal variability of the surface wind with reasonable accuracy. The model simulates the land-sea breeze cycle in the coastal region realistically, which is very clearly observed during the northeast monsoon and pre-monsoon season and is less prominent during the southwest monsoon season.

Brazilin Content, Antioxidative and Lipase Inhibition Effects of Sappanwood （Caesa/pinia Sappan） from Indonesia

Determination of brazilin by High Performance Liquid Chromatography （HPLC） method and measurement of the antioxidative and lipase inhibition effects in the Caesalpinia sappan wood from various locations in Indonesia is described in this paper. Brazilin was separated from sample matrix using a reversed phase C 18, Shim-pack VP column with the mobile phase in a gradient elution for45 min from 5% to 100% methanol in 0.05% aqueous trifluoroacetic acid. Brazilin in ethanolic extracts ofC. sappan wood was in the range of 5.81 to 24.85 mg/g on dry-weight basis. Antioxidant and lipase inhibition activities expressed by IC50 values from all samples were in the range from 6.60 to 11.53 μg/mL and 50.76 to 203.21 μg/mL, respectively. Antioxidative and lipase inhibition potency of all ethanolic extracts were compared to vitamin C and chloramphenicol, isopropyl methylphenol and tetracyclin, respectively.