卵巢局部环境与多种因素相关,其局部微环境异常与多囊卵巢综合征(Polycystic ovary syndrome, PCOS)有着密切联系。PCOS临床常表现为慢性低度炎症状态、月经后期、卵巢局部菌群异常、胰岛素抵抗以及卵泡发育异常、排卵功能障碍,这些与P...卵巢局部环境与多种因素相关,其局部微环境异常与多囊卵巢综合征(Polycystic ovary syndrome, PCOS)有着密切联系。PCOS临床常表现为慢性低度炎症状态、月经后期、卵巢局部菌群异常、胰岛素抵抗以及卵泡发育异常、排卵功能障碍,这些与PCOS卵巢局部环境异常关系密切。本文主要探讨卵巢局部的微环境异常对PCOS的影响及其作用机制,从卵巢角度对PCOS的影响进行总结,分析PCOS发生与卵巢的相关性,以期为PCOS相关研究提供参考。The local environment of ovary is related to many factors, and the abnormal local microenvironment is closely related to Polycystic ovary syndrome, PCOS). Clinical manifestations of PCOS are chronic low-grade inflammation, late menstruation, abnormal local flora of ovary, insulin resistance, abnormal follicular development and ovulation dysfunction, which are closely related to abnormal local ovarian environment of PCOS. This paper mainly discusses the influence of local microenvironment abnormality on PCOS and its mechanism, summarizes the influence on PCOS from the perspective of ovary, and analyzes the correlation between PCOS and ovary, so as to provide reference for PCOS related research.展开更多
文摘卵巢局部环境与多种因素相关,其局部微环境异常与多囊卵巢综合征(Polycystic ovary syndrome, PCOS)有着密切联系。PCOS临床常表现为慢性低度炎症状态、月经后期、卵巢局部菌群异常、胰岛素抵抗以及卵泡发育异常、排卵功能障碍,这些与PCOS卵巢局部环境异常关系密切。本文主要探讨卵巢局部的微环境异常对PCOS的影响及其作用机制,从卵巢角度对PCOS的影响进行总结,分析PCOS发生与卵巢的相关性,以期为PCOS相关研究提供参考。The local environment of ovary is related to many factors, and the abnormal local microenvironment is closely related to Polycystic ovary syndrome, PCOS). Clinical manifestations of PCOS are chronic low-grade inflammation, late menstruation, abnormal local flora of ovary, insulin resistance, abnormal follicular development and ovulation dysfunction, which are closely related to abnormal local ovarian environment of PCOS. This paper mainly discusses the influence of local microenvironment abnormality on PCOS and its mechanism, summarizes the influence on PCOS from the perspective of ovary, and analyzes the correlation between PCOS and ovary, so as to provide reference for PCOS related research.
