Apart from carpal tunnel syndrome, there are no population based studies of the epidemiology of compressive neuropathies. To provide this information, new presentations of compressive neuropathies among patients regis...Apart from carpal tunnel syndrome, there are no population based studies of the epidemiology of compressive neuropathies. To provide this information, new presentations of compressive neuropathies among patients registered with 253 general practices in the UK General Practice Research Database with 1.83 million patient years at risk in 2000 were analysed. The study revealed that in 2000 the annual age standardised rates per 100 000 of new presentations in primary care were: carpal tunnel syndrome, men 87.8/women 192.8; Morton’s metatarsalgia, men 50.2/women 87.5; ulnar neuropathy, men 25.2/women 18.9; meralgia paraesthetica, men 10.7/women 13.2; and radial neuropathy, men 2.97/women 1.42. New presentations were most frequent at ages 55-64 years except for carpal tunnel syndrome, which was most frequent in women aged 45-54 years, and radial nerve palsy, which was most frequent in men aged 75-84 years. In 2000, operative treatment was undertaken for 31%of new presentations of carpal tunnel syndrome, 3%of Morton’s metatarsalgia, and 30%of ulnar neuropathy.展开更多
Objective: Cutaneous silent period (CSP), which is a spinal reflex mediated b y A- δ cutaneous afferents, is transient suppression of the electromyographic activity. In this study, our aim is to investigate CSPs of v...Objective: Cutaneous silent period (CSP), which is a spinal reflex mediated b y A- δ cutaneous afferents, is transient suppression of the electromyographic activity. In this study, our aim is to investigate CSPs of vastus medialis musc le (vm- CSP)- evoked by the stimulation of the lateral femoral cutaneous nerve (LFCN) in healthy controls and in patients with meralgia paresthetica (MP). Met hods: Twenty- one patients with MP (17 unilateral, 4 bilateral) and 27 healthy controls were included. Nerve conduction studies of LFCN and vm- CSP were analy zed in all subjects. A stimulus train consisting of five electrical shocks was a pplied to the skin at the anterolateral side of the thigh for recording of the v m- CSP. Results: Nerve conduction abnormalities of LFCN were observed in all pa tients with MP. Mean duration of vm- CSP was 69.7± 9.2 ms, and mean onset late ncy was 44.7± 6.9 in healthy controls. Onset latency of vm- CSP was significan tly prolonged and the duration of vm- CSP was significantly shortened in patien ts with MP. Vm- CSP abnormalities were observed in 20/25 extremities with MP. C onclusions: Dysfunction of A- δ afferents may cause these findings in patient s with MP. Additionally, spinal modulation of pain may also play a role in the e xplanation of our findings. Significance: The present study demonstrates the CSP alterations in the patients with entrapment neuropathy of a cutaneous nerve.展开更多
文摘Apart from carpal tunnel syndrome, there are no population based studies of the epidemiology of compressive neuropathies. To provide this information, new presentations of compressive neuropathies among patients registered with 253 general practices in the UK General Practice Research Database with 1.83 million patient years at risk in 2000 were analysed. The study revealed that in 2000 the annual age standardised rates per 100 000 of new presentations in primary care were: carpal tunnel syndrome, men 87.8/women 192.8; Morton’s metatarsalgia, men 50.2/women 87.5; ulnar neuropathy, men 25.2/women 18.9; meralgia paraesthetica, men 10.7/women 13.2; and radial neuropathy, men 2.97/women 1.42. New presentations were most frequent at ages 55-64 years except for carpal tunnel syndrome, which was most frequent in women aged 45-54 years, and radial nerve palsy, which was most frequent in men aged 75-84 years. In 2000, operative treatment was undertaken for 31%of new presentations of carpal tunnel syndrome, 3%of Morton’s metatarsalgia, and 30%of ulnar neuropathy.
文摘Objective: Cutaneous silent period (CSP), which is a spinal reflex mediated b y A- δ cutaneous afferents, is transient suppression of the electromyographic activity. In this study, our aim is to investigate CSPs of vastus medialis musc le (vm- CSP)- evoked by the stimulation of the lateral femoral cutaneous nerve (LFCN) in healthy controls and in patients with meralgia paresthetica (MP). Met hods: Twenty- one patients with MP (17 unilateral, 4 bilateral) and 27 healthy controls were included. Nerve conduction studies of LFCN and vm- CSP were analy zed in all subjects. A stimulus train consisting of five electrical shocks was a pplied to the skin at the anterolateral side of the thigh for recording of the v m- CSP. Results: Nerve conduction abnormalities of LFCN were observed in all pa tients with MP. Mean duration of vm- CSP was 69.7± 9.2 ms, and mean onset late ncy was 44.7± 6.9 in healthy controls. Onset latency of vm- CSP was significan tly prolonged and the duration of vm- CSP was significantly shortened in patien ts with MP. Vm- CSP abnormalities were observed in 20/25 extremities with MP. C onclusions: Dysfunction of A- δ afferents may cause these findings in patient s with MP. Additionally, spinal modulation of pain may also play a role in the e xplanation of our findings. Significance: The present study demonstrates the CSP alterations in the patients with entrapment neuropathy of a cutaneous nerve.
