Terzaghi gave a theory of soil consolidation based on the effective stress principle, which was derived on several ideal assumptions to get a simplified theory. To avoid the limitations involved in Terzaghi’s theory,...Terzaghi gave a theory of soil consolidation based on the effective stress principle, which was derived on several ideal assumptions to get a simplified theory. To avoid the limitations involved in Terzaghi’s theory, many efforts are being made by scholars to solve the problems in practical engineering situations. This paper presents a generalized theory for one dimensional consolidation of saturated soft clay with variable compressibility and permeability. The semi-analytical solution presented here takes into account the well known empirical e-logk and e-logp′(σ′) relations under instantaneous loading. Study of the consolida- tion behaviors showed that the ratio of Cc and Ck (the slope of e-logp and e-logk respectively) govern the ratio of consolidation. A simulative laboratory investigation with GDS advanced consolidation system was made to analyze the clay consolidation process and compare the results with the semi-analytical solution.展开更多
Objective:This study aimed to examine the effects of mindfulness meditation on trait mindfulness,perceived stress,emotion regulation,and quality of life in end-stage renal disease patients undergoing hemodialysis.Meth...Objective:This study aimed to examine the effects of mindfulness meditation on trait mindfulness,perceived stress,emotion regulation,and quality of life in end-stage renal disease patients undergoing hemodialysis.Methods:An experimental study with repeated measures design was conducted among a sample of 74 end-stage renal disease patients undergoing hemodialysis between January and May 2021 in the dialysis center at Jahra hospital,Kuwait.The patients were randomly assigned to the experimental(n?37)and control groups(n?37).The experimental group participated in 30-min mindfulness meditation sessions(three sessions a week for five weeks)held during their hemodialysis sessions;the participants in the control group were instructed to sit with their eyes closed and relaxed for 30 min three times a week for five weeks during hemodialysis sessions.The dependent variables of both groups were measured at baseline(T0),middle of intervention(T1),and end of intervention(T2)using the Mindful Attention Awareness Scale(MAAS),Perceived Stress Scale(PSS),Emotion Regulation Questionnaire(ERQ),and Kidney Disease Quality of Life(KDQOL-36)questionnaire.The study was registered in the ClinicalTrial.gov(Identifier:NCT05176730).Results:The repeated measures ANOVA(within-subject)results for the experimental group showed that mindfulness meditation had significantly decreased perceived stress by the end of the intervention.Also,mindfulness meditation improved mindfulness,emotion regulation,and kidney disease-related quality of life in the experimental group,and this improvement occurred significantly at both T1 and T2.The repeated measures ANOVA(within and between-subject)results showed that the experimental group,as compared to the control group,had lower perceived stress,higher trait mindfulness,higher emotional regulation,and higher kidney disease-related quality of life over time.Conclusions:The positive findings of this study offer health policy-makers and hospital administrators a promising tool to use with patients undergoing hemodialysis as a way to manage stress and improve quality of life.However,this study should be replicated in multiple settings with follow-up assessments.展开更多
Impermeable bentonite or its mixtures have been proposed as candidate materials to be used in the geotechnical disposal of radioactive nuclear waste. These materials are filled in the space between a canister containi...Impermeable bentonite or its mixtures have been proposed as candidate materials to be used in the geotechnical disposal of radioactive nuclear waste. These materials are filled in the space between a canister containing radioactive nuclear waste and an underground chamber to absorb the radionuclide emitting from the canister and simultaneously retard its migration accompanying the perrneation of underground water to prevent the surrounding environment from po1lution. On the basis of the established elastoplastic strain-hardening mechanical model considering the material’s dilatancy character,the authors carry out the stress-strain analysis of a thick-wa1l cylinder in a plane strain state subJected to a pressure difference between internal and external pressures. The analysis may be expected to be a theoretical basis for developing a coupled shear and permeability test apparatus for conducting a permeability test along a sheared plane in a specimen. The apparatus will be used to study the effects of shear strain on the variation of geotechnical materials’ permeability coefficient in order to evaluate the influence of shear strain caused by nonuniform deformation and/or earthquake on the long-term safety of the disposal system of radioactive nuclear waste. The theoretlcal analysls methods in this paper can be directly spread to the analysis of the deformation and stability of tunnels or roadways driven in soft soils or high moisture-bearing soft rocks.展开更多
Hypertension is believed to be a major risk factor that causes cardiovascular disease in patients on hemodialysis （HD）. Removing of excess water during HD, accurate assessment of dry weight and anti-hypertension the...Hypertension is believed to be a major risk factor that causes cardiovascular disease in patients on hemodialysis （HD）. Removing of excess water during HD, accurate assessment of dry weight and anti-hypertension therapeutics are the most com- monly used measures to lower blood pressure in patients on HD.展开更多
Object： To observe the dynamic changes of dopamine （DA） in the striatum with the process of duplicating cerebral ischemia and reperfusion （CIR） model on rats. And observe the effect of electroacupuncture （EA） o...Object： To observe the dynamic changes of dopamine （DA） in the striatum with the process of duplicating cerebral ischemia and reperfusion （CIR） model on rats. And observe the effect of electroacupuncture （EA） on such changes. Methods： Using microdialysis sampling, high performance liquid chromatography （HPLC） detecting technology, dynamic sampling from experimental animals at multiple moments to observe the changes of dopamine in striatum with ischemia. And observe the effect of EA at Fengchi （GB 20） on such changes. Result： About the extracellular level of DA in normal group, sham-operation group and sham-operation ＋ EA group, no significant changes were observed during the measuring period. The extracellular level of DA peaked at 15-45 min after MCAO and 0-30 min （P〈0.05） after reperfusion. A rising trend was also observed following 120 min after reperfusion. After EA, the extracellular level of DA was significant lower than ischemia group following 90 min after reperfusion （P 〈0.05）. And there was no peak again. Conclusion： EA at Fenchi （GB 20） can regulate the disorder of DA. EA can improve the integrity neurological function. This may be one of the mechanisms of acupuncture treating the lesion of cerebral ischemia and reperfusion.展开更多
基金Project supported by the National Natural Science Foundation ofChina (No. 50079026) and Doctoral Subject Research Fund of Min-istry of Education (No. 20030335027) China
文摘Terzaghi gave a theory of soil consolidation based on the effective stress principle, which was derived on several ideal assumptions to get a simplified theory. To avoid the limitations involved in Terzaghi’s theory, many efforts are being made by scholars to solve the problems in practical engineering situations. This paper presents a generalized theory for one dimensional consolidation of saturated soft clay with variable compressibility and permeability. The semi-analytical solution presented here takes into account the well known empirical e-logk and e-logp′(σ′) relations under instantaneous loading. Study of the consolida- tion behaviors showed that the ratio of Cc and Ck (the slope of e-logp and e-logk respectively) govern the ratio of consolidation. A simulative laboratory investigation with GDS advanced consolidation system was made to analyze the clay consolidation process and compare the results with the semi-analytical solution.
基金funding from Jordan University of Science and Technology,Deanship of Research.
文摘Objective:This study aimed to examine the effects of mindfulness meditation on trait mindfulness,perceived stress,emotion regulation,and quality of life in end-stage renal disease patients undergoing hemodialysis.Methods:An experimental study with repeated measures design was conducted among a sample of 74 end-stage renal disease patients undergoing hemodialysis between January and May 2021 in the dialysis center at Jahra hospital,Kuwait.The patients were randomly assigned to the experimental(n?37)and control groups(n?37).The experimental group participated in 30-min mindfulness meditation sessions(three sessions a week for five weeks)held during their hemodialysis sessions;the participants in the control group were instructed to sit with their eyes closed and relaxed for 30 min three times a week for five weeks during hemodialysis sessions.The dependent variables of both groups were measured at baseline(T0),middle of intervention(T1),and end of intervention(T2)using the Mindful Attention Awareness Scale(MAAS),Perceived Stress Scale(PSS),Emotion Regulation Questionnaire(ERQ),and Kidney Disease Quality of Life(KDQOL-36)questionnaire.The study was registered in the ClinicalTrial.gov(Identifier:NCT05176730).Results:The repeated measures ANOVA(within-subject)results for the experimental group showed that mindfulness meditation had significantly decreased perceived stress by the end of the intervention.Also,mindfulness meditation improved mindfulness,emotion regulation,and kidney disease-related quality of life in the experimental group,and this improvement occurred significantly at both T1 and T2.The repeated measures ANOVA(within and between-subject)results showed that the experimental group,as compared to the control group,had lower perceived stress,higher trait mindfulness,higher emotional regulation,and higher kidney disease-related quality of life over time.Conclusions:The positive findings of this study offer health policy-makers and hospital administrators a promising tool to use with patients undergoing hemodialysis as a way to manage stress and improve quality of life.However,this study should be replicated in multiple settings with follow-up assessments.
文摘Impermeable bentonite or its mixtures have been proposed as candidate materials to be used in the geotechnical disposal of radioactive nuclear waste. These materials are filled in the space between a canister containing radioactive nuclear waste and an underground chamber to absorb the radionuclide emitting from the canister and simultaneously retard its migration accompanying the perrneation of underground water to prevent the surrounding environment from po1lution. On the basis of the established elastoplastic strain-hardening mechanical model considering the material’s dilatancy character,the authors carry out the stress-strain analysis of a thick-wa1l cylinder in a plane strain state subJected to a pressure difference between internal and external pressures. The analysis may be expected to be a theoretical basis for developing a coupled shear and permeability test apparatus for conducting a permeability test along a sheared plane in a specimen. The apparatus will be used to study the effects of shear strain on the variation of geotechnical materials’ permeability coefficient in order to evaluate the influence of shear strain caused by nonuniform deformation and/or earthquake on the long-term safety of the disposal system of radioactive nuclear waste. The theoretlcal analysls methods in this paper can be directly spread to the analysis of the deformation and stability of tunnels or roadways driven in soft soils or high moisture-bearing soft rocks.
文摘Hypertension is believed to be a major risk factor that causes cardiovascular disease in patients on hemodialysis （HD）. Removing of excess water during HD, accurate assessment of dry weight and anti-hypertension therapeutics are the most com- monly used measures to lower blood pressure in patients on HD.
基金the Science and Technology Commission of Shanghai Municipality(014319364)the Science Foundation of Shanghai Municipal Commission of Science and Technology(05DZ19745,06DZ19732,064319053,07DZ19722,07DZ19733)+1 种基金the National Basic Research Program of China(973 Program,2005CB523306)Shanghai Leading Academic Discipline Project(B112 and T0302)
文摘Object： To observe the dynamic changes of dopamine （DA） in the striatum with the process of duplicating cerebral ischemia and reperfusion （CIR） model on rats. And observe the effect of electroacupuncture （EA） on such changes. Methods： Using microdialysis sampling, high performance liquid chromatography （HPLC） detecting technology, dynamic sampling from experimental animals at multiple moments to observe the changes of dopamine in striatum with ischemia. And observe the effect of EA at Fengchi （GB 20） on such changes. Result： About the extracellular level of DA in normal group, sham-operation group and sham-operation ＋ EA group, no significant changes were observed during the measuring period. The extracellular level of DA peaked at 15-45 min after MCAO and 0-30 min （P〈0.05） after reperfusion. A rising trend was also observed following 120 min after reperfusion. After EA, the extracellular level of DA was significant lower than ischemia group following 90 min after reperfusion （P 〈0.05）. And there was no peak again. Conclusion： EA at Fenchi （GB 20） can regulate the disorder of DA. EA can improve the integrity neurological function. This may be one of the mechanisms of acupuncture treating the lesion of cerebral ischemia and reperfusion.
