The electrical performance including breakdown voltage and turn-off speed of SOI-LIGBT is improved by incorporating a resistive field plate (RFP) and a p-MOSFET.The p-MOSFET is controlled by a signal detected from a p...The electrical performance including breakdown voltage and turn-off speed of SOI-LIGBT is improved by incorporating a resistive field plate (RFP) and a p-MOSFET.The p-MOSFET is controlled by a signal detected from a point of the RFP.During the turning-off of the IGBT,the p-MOSFET is turned on,which provides a channel for the excessive carriers to flow out of the drift region and prevents the carriers from being injected into the drift region.At the same time,the electric field affected by the RFP makes the excessive carriers flow through a wider region,which almost eliminates the second phase of the turning-off of the SOI-LIGBT caused by the substrate bias.Faster turn-off speed is achieved by above two factors.During the on state of the IGBT,the p-MOSFET is off,which leads to an on-state performance like normal one.At least,the increase of the breakdown voltage for 25% and the decrease of the turn-off time for 65% can be achieved by this structure as can be verified by the numerical simulation results.展开更多
Eighty-seven patients with different types of diseases were treated with acupuncture,and the changes of their blood pressure were investigated.The results showed that the total level of systolic pressure in the 87 cas...Eighty-seven patients with different types of diseases were treated with acupuncture,and the changes of their blood pressure were investigated.The results showed that the total level of systolic pressure in the 87 cases decreased (P<0.05).Especially,the systolic pressure in patients accompanied with hypertension decreased significantly.It is suggested that when acupuncture is adopted to treat other diseases,it can decrease the systolic pressure to a certain extent in patients accompanied with hypertension,but it does not exert significant influence on both systolic and diastolic pressure in patients with normal blood pressure.展开更多
A high-accuracy,low-dropout (LDO) voltage regulator is presented. Using the slow-rolloff frequency compensation scheme, the LDO effectively overcomes the stability problem, facilitates the use of a ceramic capacitor...A high-accuracy,low-dropout (LDO) voltage regulator is presented. Using the slow-rolloff frequency compensation scheme, the LDO effectively overcomes the stability problem, facilitates the use of a ceramic capacitor, and improves the output voltage accuracy, which is critical for powering high-performance analog circuitry. The slow-rolloff compensation scheme is realized by introducing three pole-zero pairs, including the proposed polezero pair and sense zero. The post-layout simulation results demonstrate that this LDO has robust system stability, a high open-loop gain, and a high unit-gain frequency,which lead to excellent regulation and transient response performance. The line and load regulation are 27μV/V and 3.78μV/mA, and the overshoots of the output voltage are less than 30mV,while the dropout voltage is 120mV for a 150mA load current.展开更多
In order to observe the therapeutic effects of Huanglian Fire-Purging Mixture (黄连清降合剂) on primary hypertension, 46 cases of primary hypertension in the treatment group were treated with Huanglian Fire-Purging Mi...In order to observe the therapeutic effects of Huanglian Fire-Purging Mixture (黄连清降合剂) on primary hypertension, 46 cases of primary hypertension in the treatment group were treated with Huanglian Fire-Purging Mixture to clear away heat from the liver, relieve mental stress, purge fire and remove toxin;and the other 26 cases of primary hypertension in the control group were treated with Niuhuang Bolus for Lowering Blood Pressure (牛黄降压丸). The effect in the treatment group was obviously superior to that in the control group (P<0.05). The Huanglian Fire-Purging Mixture shows noticeable effects 3-6 hours after medication. The mixture can improve the clinical symptoms, the left ventricular diastolic function and myocardial ischemia, correct dyslipoproteinemia and dysglycemia, and reduce blood viscosity. And it is safe and with no obvious adverse reactions.展开更多
The hydrodynamics and mass transfer of Plum Flower Mini Ring (PFMR), Pall Ring and Intalox Saddle were studied in a 600 mm diameter column with air-oxygen-water system over a wide range of liquid loads. It was shown f...The hydrodynamics and mass transfer of Plum Flower Mini Ring (PFMR), Pall Ring and Intalox Saddle were studied in a 600 mm diameter column with air-oxygen-water system over a wide range of liquid loads. It was shown from the experiments that PFMR had much lower resistance, larger throughput and higher mass transfer efficiency than Pall Ring and Intalox Saddle. It was clear from the comparison that existing equations could not predict the performance of packings very well at high liquid loads. Therefore, new semi-empirical equations of pressure drop, flooding gas velocity and height of transfer unit (HTU) were proposed based on the experimental data.展开更多
Pressure drops are of major importance for distillation/absorption columns. This paper mainly discusses how to correctly measure, interpret and use pressure drop data. The possible causes of incorrect pressure drop me...Pressure drops are of major importance for distillation/absorption columns. This paper mainly discusses how to correctly measure, interpret and use pressure drop data. The possible causes of incorrect pressure drop measurements are studied including the effects of pressure tap dimensions, locations, and vapor condensation etc. The effect of the static head of vapor on the pressure drop data and column pressures is evaluated. Variations of sectional pressure drops along the column are investigated based on the experimental data obtained from commercial size distillation columns at Fractionation Research, Inc. (FRI). For a packed column, it is found that the spacing between the liquid distributor and the top of the bed affects the overall pressure drop measurements, which is confirmed by a fundamental fluid dynamics analysis.展开更多
Magnesium alloys,as a new generation temporary biomaterial,deserve the desirable biocompatibility and biodegradability,and also contribute to the repair of the damaged bone tissues.However,they do not possess the requ...Magnesium alloys,as a new generation temporary biomaterial,deserve the desirable biocompatibility and biodegradability,and also contribute to the repair of the damaged bone tissues.However,they do not possess the required corrosion resistance in human body fluid.Hot mechanical workings,such as extrusion,influence both the mechanical properties and bio-corrosion behavior of magnesium alloys.This review aims to gather information on how the extrusion parameters(extrusion ratio and temperature)influence the bio-corrosion performances of magnesium alloys.Their effects are mainly ascribed to the alteration of extruded alloy microstructure,including final grain size and uniformity of grains,texture,and the size,distribution and volume fraction of the second phases.Dynamic recrystallization and grain refinement during extrusion provide a more homogeneous microstructure and cause the formation of basal texture,resulting in improved strength and corrosion resistance of magnesium alloy.Extrusion temperature and extrusion ratio are reported as the influential factors in the degradation.The reports reveal that the increase in extrusion ratio and/or the reduction in extrusion temperature cause a decrease in the final grain size,leading to intensification of basal texture,in parallel side of the samples with extrusion line,and to lower volume fraction and size of precipitates in magnesium alloys.These all lead to improving the bio-corrosion resistance of the magnesium alloy implants.展开更多
As for the coal seam with high stress,high gas and low permeability,a single technology cannot prevent the complex dynamic disasters.Because of this,the study proposes a new method of pressure-relief and permeability-...As for the coal seam with high stress,high gas and low permeability,a single technology cannot prevent the complex dynamic disasters.Because of this,the study proposes a new method of pressure-relief and permeability-increase technology of the high liquid–solid coupling blast.Through coal seam injection and charging structure change,the paper fully works out the dual functions of the water and explosion.Using the theoretical calculation,numerical simulation and physical experiments,we obtained that the initial blasting stress,displacement and overpressure of the liquid–solid coupling blast are much better than that of ordinary blasting.The technology has been used in the relative coal mine,and the application results show that the technique has effectively prevented the coal and gas outburst,which has a wide range of application.展开更多
The natural frequency of the electrohydraulic system in mobile machinery is always very low,which brings difficulties to the controller design.To improve the tracking performance of the hydraulic system,mathematical m...The natural frequency of the electrohydraulic system in mobile machinery is always very low,which brings difficulties to the controller design.To improve the tracking performance of the hydraulic system,mathematical modeling of the electrohydraulic lifting system and the rubber hose was accomplished according to an electrohydraulic lifting test rig built in the laboratory.Then,valve compensation strategy,including spool opening compensation (SOC) and dead zone compensation (DZC),was designed based on the flow-pressure characteristic of a closed-centered proportional valve.Comparative experiments on point-to-point trajectory tracking between a proportional controller with the proposed compensations and a traditional PI controller were conducted.Experiment results show that the maximal absolute values of the tracking error are reduced from 0.039 m to 0.019 m for the slow point-to-point motion trajectory and from 0.085 m to 0.054 m for the fast point-to-point motion trajectory with the proposed compensations.Moreover,tracking error of the proposed controller was analyzed and corresponding suggestions to reduce the tracking error were put forward.展开更多
Orphanin FQ(OFQ) or nociceptin is a novel neuropeptide consisting of 17 amino acids. This peptide has a primary structure reminiscent of that of opioid peptide but exhibits an opposite effect to make animals hyperre...Orphanin FQ(OFQ) or nociceptin is a novel neuropeptide consisting of 17 amino acids. This peptide has a primary structure reminiscent of that of opioid peptide but exhibits an opposite effect to make animals hyperreactive. The effect of this new peptide on cardiovascular function are not completely known. The present study was conducted to investigate the effect of intravenous bolus injection of orphanin FQ on mean arterial blood presure (MABP) in conscious stroke-prone spontaneously hypertensive rats (SHRsp). Adult male SHRsp and Wistar normotensive rats (250~300 g body weight, 2. 5~3 months old) were used in this study. The MABP was measured in the conscious state by a tail-cuff method. In SHRsp model, intravenous bolus injection of orphanin FQ or Tyr1-orphanin FQ (0. 5 mg/kg) induced a prolonged and marked reduc- tion in MABP. The maximum changes in MABP were -30. 2±4. 2 mmHg by orphanin FQ and -28. 2± 4. 7 mmHg by Tyr1-orphanin FQ at 10 min after administration,and this effect lasted over 30 min. The Phe1→Tyr substitution in orphanin FQ was found to retain almost fully hypotensive activity. Pretreatment of SHRsp with naloxone-HCI(60 μg/kg), 5 min before the injection of orphanin FQ, did not block the hy- potensive effect of orphanin FQ. Therefore, opioid receptors could not account for the hypotensive effect of orphanin FQ in SHRsp. In Wistar rats, intravenous bolus injection of the same dose of orphanin FQ did not cause a change in MABP. These observations suggest that orphanin FQ is a novel hypotensive peptide and may have some role in the regulation of blood pressure in SHRsp, rather than in normotensive rats. The ex-act underlying mechanisms are waiting to be clarified.展开更多
This research describes an integrated multi-channel high accuracy current control LED (light emitting diode) driver with low dropout regulator implemented in a 0.35μm TSMC 2P4M CMOS process. With the new trend of b...This research describes an integrated multi-channel high accuracy current control LED (light emitting diode) driver with low dropout regulator implemented in a 0.35μm TSMC 2P4M CMOS process. With the new trend of backlighting applications for mobile electronics and portable devices requiring a smaller size, lower cost, lesser noise and accurate current control LED driver, it came up with the idea of integrating more than one design features within a single chip. The analysis of using a capacitor-less low dropout regulator to power the constant current source has been explored, with the implementation of wide range battery voltage of 3 V to 5 V. Possible load current variations were introduced and verified to output a fixed voltage of 2.8 V. A regulated cascode current mirror structure forms the multi-channel configuration string of LED's; the design ensures a current matching of less than 1% error and achieves a high accuracy current control of less than 1% error, regardless of the LED's forward voltage variation. Moreover, for high end portable device with multimedia applications, dimming frequency can be set to 10 MHz. In addition, a switching output is a better approach for managing LED's contrast and brightness adjustment as well as maximizing power consumption, ensuring longer life for driving string of LEDs.展开更多
A predictive current control algorithm for the Buck-Boost DC-DC converter is presented in this paper. The continuous time model of the system is properly introduced, then, by imposing a proper PWM modulation pattern, ...A predictive current control algorithm for the Buck-Boost DC-DC converter is presented in this paper. The continuous time model of the system is properly introduced, then, by imposing a proper PWM modulation pattern, its discrete time model is achieved. This last one is successfully employed in determining the steady state locus of the Buck-Boost converter, both in CCM (continuous conduction mode) and DCM (discontinuous conduction mode). A novel continuous time equivalent circuit of the converter is introduced too, with the aim of determining a ripple free representation of the state variables of the system, over both transient and steady state operation. Then, a predictive current control algorithm, suitable in both CCM and DCM, is developed and properly checked by means of computer simulations. The corresponding results have highlighted the effectiveness of the proposed modelling and of the predictive control algorithm, both in CCM and DCM.展开更多
文摘The electrical performance including breakdown voltage and turn-off speed of SOI-LIGBT is improved by incorporating a resistive field plate (RFP) and a p-MOSFET.The p-MOSFET is controlled by a signal detected from a point of the RFP.During the turning-off of the IGBT,the p-MOSFET is turned on,which provides a channel for the excessive carriers to flow out of the drift region and prevents the carriers from being injected into the drift region.At the same time,the electric field affected by the RFP makes the excessive carriers flow through a wider region,which almost eliminates the second phase of the turning-off of the SOI-LIGBT caused by the substrate bias.Faster turn-off speed is achieved by above two factors.During the on state of the IGBT,the p-MOSFET is off,which leads to an on-state performance like normal one.At least,the increase of the breakdown voltage for 25% and the decrease of the turn-off time for 65% can be achieved by this structure as can be verified by the numerical simulation results.
文摘Eighty-seven patients with different types of diseases were treated with acupuncture,and the changes of their blood pressure were investigated.The results showed that the total level of systolic pressure in the 87 cases decreased (P<0.05).Especially,the systolic pressure in patients accompanied with hypertension decreased significantly.It is suggested that when acupuncture is adopted to treat other diseases,it can decrease the systolic pressure to a certain extent in patients accompanied with hypertension,but it does not exert significant influence on both systolic and diastolic pressure in patients with normal blood pressure.
文摘A high-accuracy,low-dropout (LDO) voltage regulator is presented. Using the slow-rolloff frequency compensation scheme, the LDO effectively overcomes the stability problem, facilitates the use of a ceramic capacitor, and improves the output voltage accuracy, which is critical for powering high-performance analog circuitry. The slow-rolloff compensation scheme is realized by introducing three pole-zero pairs, including the proposed polezero pair and sense zero. The post-layout simulation results demonstrate that this LDO has robust system stability, a high open-loop gain, and a high unit-gain frequency,which lead to excellent regulation and transient response performance. The line and load regulation are 27μV/V and 3.78μV/mA, and the overshoots of the output voltage are less than 30mV,while the dropout voltage is 120mV for a 150mA load current.
文摘In order to observe the therapeutic effects of Huanglian Fire-Purging Mixture (黄连清降合剂) on primary hypertension, 46 cases of primary hypertension in the treatment group were treated with Huanglian Fire-Purging Mixture to clear away heat from the liver, relieve mental stress, purge fire and remove toxin;and the other 26 cases of primary hypertension in the control group were treated with Niuhuang Bolus for Lowering Blood Pressure (牛黄降压丸). The effect in the treatment group was obviously superior to that in the control group (P<0.05). The Huanglian Fire-Purging Mixture shows noticeable effects 3-6 hours after medication. The mixture can improve the clinical symptoms, the left ventricular diastolic function and myocardial ischemia, correct dyslipoproteinemia and dysglycemia, and reduce blood viscosity. And it is safe and with no obvious adverse reactions.
文摘The hydrodynamics and mass transfer of Plum Flower Mini Ring (PFMR), Pall Ring and Intalox Saddle were studied in a 600 mm diameter column with air-oxygen-water system over a wide range of liquid loads. It was shown from the experiments that PFMR had much lower resistance, larger throughput and higher mass transfer efficiency than Pall Ring and Intalox Saddle. It was clear from the comparison that existing equations could not predict the performance of packings very well at high liquid loads. Therefore, new semi-empirical equations of pressure drop, flooding gas velocity and height of transfer unit (HTU) were proposed based on the experimental data.
文摘Pressure drops are of major importance for distillation/absorption columns. This paper mainly discusses how to correctly measure, interpret and use pressure drop data. The possible causes of incorrect pressure drop measurements are studied including the effects of pressure tap dimensions, locations, and vapor condensation etc. The effect of the static head of vapor on the pressure drop data and column pressures is evaluated. Variations of sectional pressure drops along the column are investigated based on the experimental data obtained from commercial size distillation columns at Fractionation Research, Inc. (FRI). For a packed column, it is found that the spacing between the liquid distributor and the top of the bed affects the overall pressure drop measurements, which is confirmed by a fundamental fluid dynamics analysis.
文摘Magnesium alloys,as a new generation temporary biomaterial,deserve the desirable biocompatibility and biodegradability,and also contribute to the repair of the damaged bone tissues.However,they do not possess the required corrosion resistance in human body fluid.Hot mechanical workings,such as extrusion,influence both the mechanical properties and bio-corrosion behavior of magnesium alloys.This review aims to gather information on how the extrusion parameters(extrusion ratio and temperature)influence the bio-corrosion performances of magnesium alloys.Their effects are mainly ascribed to the alteration of extruded alloy microstructure,including final grain size and uniformity of grains,texture,and the size,distribution and volume fraction of the second phases.Dynamic recrystallization and grain refinement during extrusion provide a more homogeneous microstructure and cause the formation of basal texture,resulting in improved strength and corrosion resistance of magnesium alloy.Extrusion temperature and extrusion ratio are reported as the influential factors in the degradation.The reports reveal that the increase in extrusion ratio and/or the reduction in extrusion temperature cause a decrease in the final grain size,leading to intensification of basal texture,in parallel side of the samples with extrusion line,and to lower volume fraction and size of precipitates in magnesium alloys.These all lead to improving the bio-corrosion resistance of the magnesium alloy implants.
基金provided by the National Eleventh Five-Year scientific and Technological Support Plan Subject of China (No.2007BAK29B01)the National Natural Science Foundation (No.50534090)+2 种基金the National Key Basic Research Development Program of China (No.2011CB201205)State Key Laboratory of Coal Resources and Mine Safety of China University of Mining Technology of China (No.SKLCRSM08X03)the Youth Science and Technology Fund of China University of Mining and Technology (No.JGY101605)
文摘As for the coal seam with high stress,high gas and low permeability,a single technology cannot prevent the complex dynamic disasters.Because of this,the study proposes a new method of pressure-relief and permeability-increase technology of the high liquid–solid coupling blast.Through coal seam injection and charging structure change,the paper fully works out the dual functions of the water and explosion.Using the theoretical calculation,numerical simulation and physical experiments,we obtained that the initial blasting stress,displacement and overpressure of the liquid–solid coupling blast are much better than that of ordinary blasting.The technology has been used in the relative coal mine,and the application results show that the technique has effectively prevented the coal and gas outburst,which has a wide range of application.
基金Project(2006CB705400)supported by the National Basic Research Program of China
文摘The natural frequency of the electrohydraulic system in mobile machinery is always very low,which brings difficulties to the controller design.To improve the tracking performance of the hydraulic system,mathematical modeling of the electrohydraulic lifting system and the rubber hose was accomplished according to an electrohydraulic lifting test rig built in the laboratory.Then,valve compensation strategy,including spool opening compensation (SOC) and dead zone compensation (DZC),was designed based on the flow-pressure characteristic of a closed-centered proportional valve.Comparative experiments on point-to-point trajectory tracking between a proportional controller with the proposed compensations and a traditional PI controller were conducted.Experiment results show that the maximal absolute values of the tracking error are reduced from 0.039 m to 0.019 m for the slow point-to-point motion trajectory and from 0.085 m to 0.054 m for the fast point-to-point motion trajectory with the proposed compensations.Moreover,tracking error of the proposed controller was analyzed and corresponding suggestions to reduce the tracking error were put forward.
文摘Orphanin FQ(OFQ) or nociceptin is a novel neuropeptide consisting of 17 amino acids. This peptide has a primary structure reminiscent of that of opioid peptide but exhibits an opposite effect to make animals hyperreactive. The effect of this new peptide on cardiovascular function are not completely known. The present study was conducted to investigate the effect of intravenous bolus injection of orphanin FQ on mean arterial blood presure (MABP) in conscious stroke-prone spontaneously hypertensive rats (SHRsp). Adult male SHRsp and Wistar normotensive rats (250~300 g body weight, 2. 5~3 months old) were used in this study. The MABP was measured in the conscious state by a tail-cuff method. In SHRsp model, intravenous bolus injection of orphanin FQ or Tyr1-orphanin FQ (0. 5 mg/kg) induced a prolonged and marked reduc- tion in MABP. The maximum changes in MABP were -30. 2±4. 2 mmHg by orphanin FQ and -28. 2± 4. 7 mmHg by Tyr1-orphanin FQ at 10 min after administration,and this effect lasted over 30 min. The Phe1→Tyr substitution in orphanin FQ was found to retain almost fully hypotensive activity. Pretreatment of SHRsp with naloxone-HCI(60 μg/kg), 5 min before the injection of orphanin FQ, did not block the hy- potensive effect of orphanin FQ. Therefore, opioid receptors could not account for the hypotensive effect of orphanin FQ in SHRsp. In Wistar rats, intravenous bolus injection of the same dose of orphanin FQ did not cause a change in MABP. These observations suggest that orphanin FQ is a novel hypotensive peptide and may have some role in the regulation of blood pressure in SHRsp, rather than in normotensive rats. The ex-act underlying mechanisms are waiting to be clarified.
文摘This research describes an integrated multi-channel high accuracy current control LED (light emitting diode) driver with low dropout regulator implemented in a 0.35μm TSMC 2P4M CMOS process. With the new trend of backlighting applications for mobile electronics and portable devices requiring a smaller size, lower cost, lesser noise and accurate current control LED driver, it came up with the idea of integrating more than one design features within a single chip. The analysis of using a capacitor-less low dropout regulator to power the constant current source has been explored, with the implementation of wide range battery voltage of 3 V to 5 V. Possible load current variations were introduced and verified to output a fixed voltage of 2.8 V. A regulated cascode current mirror structure forms the multi-channel configuration string of LED's; the design ensures a current matching of less than 1% error and achieves a high accuracy current control of less than 1% error, regardless of the LED's forward voltage variation. Moreover, for high end portable device with multimedia applications, dimming frequency can be set to 10 MHz. In addition, a switching output is a better approach for managing LED's contrast and brightness adjustment as well as maximizing power consumption, ensuring longer life for driving string of LEDs.
文摘A predictive current control algorithm for the Buck-Boost DC-DC converter is presented in this paper. The continuous time model of the system is properly introduced, then, by imposing a proper PWM modulation pattern, its discrete time model is achieved. This last one is successfully employed in determining the steady state locus of the Buck-Boost converter, both in CCM (continuous conduction mode) and DCM (discontinuous conduction mode). A novel continuous time equivalent circuit of the converter is introduced too, with the aim of determining a ripple free representation of the state variables of the system, over both transient and steady state operation. Then, a predictive current control algorithm, suitable in both CCM and DCM, is developed and properly checked by means of computer simulations. The corresponding results have highlighted the effectiveness of the proposed modelling and of the predictive control algorithm, both in CCM and DCM.