蒲家庄原源变迁之析

传承史说及文献简记,对淄邑先后两处蒲家庄的由来进行分析后发现,原蒲家庄(今高家店子)乃由中原汉蒲于宋初战乱中东迁,在淄邑城区孝妇河畔建庄定居的中原汉蒲的一支族庄。另外,元末诛灭蒲族以后,遗孤蒲璋于东乡由外祖杨家庄的杨家外迁至东谷柳泉井附近,至明初,因此地蒲姓户众,便称为蒲家庄。这是淄邑第二处蒲家庄的由来。

设想美好未来,计谋可期天下的有意识构想实现行为

人工智能在硬件、软件、数据、算法、算力、安全、系统、生态8个方面与创新设计结合,进行ID识别、行为模式和需求关系的智能设计,智能感知、智能认知、智能控制、智能网络、智能运算将人类智能的关联、预测和想象核心能力进行模拟学习,完成设想未来、计谋天下的设计活动,提高有意识构想行为,实现三体元宇宙(原宇宙、源宇宙)元设计创造未来可能性的概率。通过高信维、高感质、高交互、高价值和高颜值的设计评测,用科技美学科技伦理实现共生的数实生态文明可持续发展。

Skin care efficacy study of recombinant humanized collagen based on in vitro level

Studying the skin care efficacy of recombinant humanized collagen based on in vitro level.The stability of the recombinant humanized collagen was first analyzed by treating at different temperatures,then its skincare efficacy based on in vitro level was evaluated by detecting the inhibition rate of elastase,the inhibition rate of collagenase,the protein content of type I collagen in human fibroblasts,the inhibition of reactive oxygen species(ROS)with human keratinocytes,and the effects of the recombinant humanized collagen on the expression of hyaluronic acid(HA),filaggrin(FLG)and transglutaminase 1(TGM1)in keratinocytes.The results showed that recombinant humanized collagen was able to maintain stability at temperatures below 70℃.With regard to its skincare efficacy,recombinant humanized collagen could inhibit elastase and collagenase activities and promote the increase of type I collagen content in human fibroblasts.It also showed good inhibition of ROS in keratinocytes in vitro and could increase the expression of HA,FLG,and TGM1 in keratinocytes.In short,the recombinant humanized collagen exhibited a favourable skin care effect in vitro level.This study proved that it has potential firming,anti-wrinkle,moisturizing,and repairing efficacy,and is a valuable cosmetic raw material.

关于中国传统伦理现代价值研究的方法论思考

为了使当前的传统伦理现代价值研究进一步深入,对这一研究的方法论问题有必要作进一步的思考。任何社会伦理建构,都有"原"、"源"两方面的综’合成因,只有遵循"原源之辨"的历史辩证法,才能处理好传统伦理与现代伦理建构的关系,而要正确处理这个问题,首先就必须正确确定传统伦理的"现代价值对象性",从而再进一步探索古今"通理"与"现代价值对象性"的关系,于是我们可以看到:传统伦理现代价值是一种价值再创造。

用厚源α计数测定TL和ESR年代中的钍,铀年剂量

本文叙述了用厚源α计数技术测定TL和ESR年代中钍系和铀系年剂量的原理和方法。该方法主要优点是测定α年剂量时,可将计数率直接代入生龄公式,不需要计算钍、铀含量和剂量率转换因子。但在估算β和γ年剂量时,必须假定样品中的钍、铀放射性是相同的,或者用“对”技术来确定钍、铀含量。

有源箝位PWM控制器UCC3580的原理及应用

介绍了Unitrode公司的有源箝位PWM控制器UCC3580的原理及应用 ,详细说明了该控制器的内部组成、引脚定义及工作原理 ,给出了一个有源箝位单端正激变换电路 ,并通过该电路对UCC3580的应用进行了说明。

Changes of the Transcriptional Levels of Molecules Associated with Endogenous Antigen Processing and Presentation in Porcine Skin-derived Dendritic Cells Infected with PCV2 in vivo

[Objective] This study aimed to investigate the changes of the transcriptional levels of molecules associated with endogenous antigen processing and presenta- tion in porcine skin-derived dendritic cells infected with PCV2 in vivo. [Method] Healthy 40-day-old Landrace piglets were infected with porcine circovirus type 2 （PCV2） and euthanized on the 34, 7rd, 14th, 21st and 35th d post inoculation （DPI）. The porcine skin-derived dendritic cells （DCs） were collected to analyze the transcrip- tional levels of molecules （LMP7, UBP, MHC-I, calreticulin） associated with endogenous antigen processing and presentation by using real-time fluorescent quantitative PCR （real-time FQ-PCR）. [Result] The results showed that the level of LMP7 mR- NAs was reduced significantly on the 3DPI （P〈0.05）; the level of UBP mRNAs was consistently up-regulated, which increased significantly on the 21DPI and 35DPI （P〈 0.05）; the level of MHC-I mRNAs was significantly down-regulated on the 7DPI （P〈 0.05）; the level of calreticulin mRNAs was up-regulated slightly without significant dif- ference. [Conclusion] PCV2 can inhibit the endogenous antigen processing and presentation ability of porcine skin-derived DCs at early stages of infection.

环境设计的“原”“源”意涵解析

“原”和“源”是文化形成的重要基础与必要条件,是设计创作者达成设计意义的前提和保障。且因环境设计在文化呈现上的特殊性,其“原”和“源”的构建应被赋予更为广阔的内涵拓展和更为丰富的层次创设。对环境设计“原”和“源”的深入理解,有利于设计师建立正确的环境观念以指导具体设计。

Physical Mapping of the Sequences Homologous to Disease Resistance Genes myb1 and NDR1 in Maize

Using fluorescence in situ hybridization, the authors investigated the homology between three plant species, maize (Zea mays L.) and tobacco (Nicotiana tabacum L.), maize and Arabidopsis thaliana (L.) Heynh. at cytogenetic level using two probes corresponding to functional disease resistance genes myb1 and NDR1 in Arabidopsis and tobacco respectively. The hybridization signals of the tested probes were detected in maize chromosomes 8 and 5 respectively, and the single location of each of the two probes showed only single copy of them in maize genome. The results provided a valuable insight into searching for genes associated with programmed cell death in plants using heterologous probe with comparative genetic approach. In addition, the improvements of FISH technique using heterologous probes were discussed.

Production of Somatic Hybrid Plants Between Two Types of Wheat Protoplasts and the Protoplasts of Haynaldia villosa

小麦 (TriticumaestivumL .)济南 177的两种原生质体 ,一种来自快速生长的悬浮细胞 ,它们因长期继代而丧失分化能力 ,其染色体只有 2n =2 4～ 2 8;另一种来自可以再生的愈伤组织 ,其原生质体不能持续分裂。它们中任一种与UV照射过的簇毛麦原生质体融合均不能再生植株。然而当它们混合在一起作为受体时 ,能够获得再生绿色植株。细胞核基因和胞质基因的分析证明这些绿色植株是杂种。以上事实说明这两种原生质体在融合时存在某些互补的关系 ,讨论了这种融合方式的可能作用及重要性。

Bile acids as endogenous etiologic agents in gastrointestinal cancer

Bile acids are implicated as etiologic agents in cancer of the gastrointestinal (GI) tract, including cancer of the esophagus, stomach, small intestine, liver, biliary tract, pancreas and colon/rectum. Deleterious effects of bile acid exposure, likely related to carcinogenesis, include: induction of reactive oxygen and reactive nitrogen species; induction of DNA damage; stimulation of mutation; induction of apoptosis in the short term, and selection for apoptosis resistance in the long term. These deleterious effects have, so far, been reported most consistently in relation to esophageal and colorectal cancer, but also to some extent in relation to cancer of other organs. In addition, evidence is reviewed for an association of increased bile acid exposure with cancer risk in human populations, in specific human genetic conditions, and in animal experiments. A model for the role of bile acids in GI carcinogenesis is presented from a Darwinian perspective that offers an explanation for how the observed effects of bile acids on cells contribute to cancer development.

Preparation and characterization of Martian soil simulant NEU Mars-1

To develop Martian soil simulant,basalts of the Chahar volcanic group in Wulanchabu,Inner Mongolia,China were selected as the simulant initial materials,which were ground and sorted to a predetermined particle size ratio,and small amounts of magnetite and hematite were added.The main phases of NEU Mars-1 simulant were plagioclase,augite and olivine.The glass transition and crystallization temperatures of NEU Mars-1 were 547.8 and 795.7°C,respectively.The complex dielectric constant,magnetic conductivity(0.99-1.045),and dielectric loss tangent angles(0.0025-0.030)of NEU Mars-1 were all stable in the frequency range of 2-18 GHz.Mossbauer spectroscopy results showed that the mass ratio of Fe2+to Fe3+in the simulant was 77.6:22.4.The NEU Mars-1 Martian soil simulant demonstrated particle size ratio,chemical composition,phase composition,thermal stability,and dielectric property similar to Martian soil,and can be used as the substitute material to extract oxygen and metals with in-situ resource utilization technologies.

Membrane Engineering for Green Process Engineering

Green process engineering, which is based on the principles of the process intensification strategy, can provide an important contribution toward achieving industrial sustainable development. Green process engineering refers to innovative equipment and process methods that are expected to bring about substan- tial improvements in chemical and any other manufacturing and processing aspects. It includes decreasing production costs, equipment size, energy consumption, and waste generation, and improving remote con- trol, information fluxes, and process flexibility. Membrane-based technology assists in the pursuit of these principles, and the potential of membrane operations has been widely recognized in the last few years. This work starts by presenting an overview of the membrane operations that are utilized in water treatment and in the production of energy and raw materials. Next, it describes the potential advantages of innovative membrane-based integrated systems. A case study on an integrated membrane system （IMS） for seawa- ter desalination coupled with raw materials production is presented. The aim of this work is to show how membrane systems can contribute to the realization of the goals of zero liquid discharge （ZLD）, total raw materials utilization, and low energy consumption.

Uncertainties in Quantitatively Estimating the Atmospheric Heat Source over the Tibetan Plateau

As a huge,intense,and elevated atmospheric heat source(AHS) approaching the mid-troposphere in spring and summer,the Tibetan Plateau(TP) thermal forcing is perceived as an important factor contributing to the formation and variation of the Asian summer monsoon.Despite numerous studies devoted to determine the strength and change of the thermal forcing of the TP on the basis of various data sources and methods,uncertainties remain in quantitative estimation of the AHS and will persist for the following reasons:(1) Routine meteorological stations cover only limited regions and show remarkable spatial inhomogeneity with most distributed in the central and eastern plateau.Moreover,all of these stations are situated at an altitude below 5000 m.Thus,the large area above that elevation is not included in the data.(2) Direct observations on heat fluxes do not exist at most stations,and the sensible heat flux(SHF) is calculated by the bulk formula,in which the drag coefficient for heat is often treated as an empirical constant without considering atmospheric stability and thermal roughness length.(3) Radiation flux derived by satellite remote sensing shows a large discrepancy in the algorithm in data inversion and complex terrain.(4) In reanalysis data,besides the rare observational records employed for data assimilation,model bias in physical processes induces visible errors in producing the diabatic heating fields.

Photochemical degradation of crude oil in seawater

Photochemical degradation of crude oil in seawater is an important issue in marine environ- mental protection and is studied in this work. Results showed that petroleum hydrocarbons could be ef- fectively degraded by the irradiation of high-pressure mercury light or natural sunlight. Photochemical reaction was controlled by various factors including light source, aquatic medium, heavy metal ion and photo-sensitizer. The rate of photo-degradation was fast at the initial stage of exposure, exhibiting a first-order reaction kinetic behavior. However, after irradiation for a few hours, the concentration of wa- ter-soluble fraction (WSF) of petroleum hydrocarbons stabilized. For all experimental conditions, the range of the photo-degradation rate is from 0.001 3 to 0.005 7/min.

Hidden Symmetries for Thermodynamics and Emergence of Relativity

Erik Verlinde recently proposed an idea about the thermodynamic origin of gravity.Though this is abeautiful idea, which may resolve many long standing problems in the theories of gravity, it also raises many otherproblems.In this article I will comment on some of the problems of Verlinde’s proposal with special emphasis on thethermodynamical origin of the principle of relativity.It is found that there is a large group of hidden symmetries ofthermodynamics, which contains the Poincare group of the spacetime for which space is emergent.This explains thethermodynamic origin of the principle of relativity.

Further development and sustainable utilization mode of grassland tourism resources: a case study of Inner Mongolia Autonomous Region, China

Tourism resources are important foundation for the development of tourism industry.Grassland is not only a kind of important resource but also a great attraction to visitors.Therefore,the integrated development and sustainable utilization of grassland tourism resources are of great significance.This paper,based on the analysis of literatures and the current problems existing in grassland tourism,summarizes the speciality of grassland tourism development,deals nation as example and carries out empirical research.Based on the status quo of grassland tourism resources in Inner Mongolia,this study analyzes the characteristics of grassland tourism resources,the necessity and feasibility of integrated development,then proposes the following suggestions： idea for development,mode of development,regional cooperation,tourism products development,especially the three modes of development based on the resources conditions - the mode of relying on market,the mode of combination aggregation and the mode of relying on quality.

Rangeland Privatization and Its Impacts on the Zoige Wetlands on the Eastern Tibetan Plateau

The high Zoige Basin （Ruoergai Plateau） on the eastern Tibetan Plateau is a fault depression formed during intensive uplifting of the Tibetan Plateau. The wetland is globally important in biodiversity and is composed of marshes, bogs, fens, wet meadows and shallow water interspersed with low hills and sub-alpine meadows. Most of the Zoige wetlands have long been one of the most important grazing lands in China. Recent rangeland policy has allowed grazing, and usable wetland areas have been being legally allocated to individuals or groups of households on a long-term lease basis. Privatizafion of the wetland has impacted the Zoige wetlands in aspects of hydrologic condition, landscape and biodiversity. The uneven spatial distribution of water resources onprivatelands has led to the practice of extracting ground water, which has decreased the perched water table in Zoige. Fencing off the rangelands and grazing on expanding sand dunes have affected landscapes. Variation in the water table has led to the changes in vegetation diversity, resulting in the changes in wildlife and aquatic diversities and ecosystem processes. Making use all year round of the pasture that was previously grazed only in summer has shrunk the daily activity space of wildlife, and the newly erected fences blocked the movement of wild animals looking for food in the snow to lower and open areas. To maintain the favorable conditions of the Zoige wetland ecosystem, the author suggests that, in addition to biophysical research and implementation of conservation practices, there is an immediate need to initiate an integrated management program, increase public awareness of wetland functions and provide better training for the local conservation staff.

Integration and Optimized Utilization of Naphtha Resources

Naphtha is an important raw material for manufacture of clean fuels and ethylene products. However, China is experiencing a serious imbalance between supply and demand of naphtha, due to its rapidly increasing car population and booming ethylene industry, the demand of which cannot be met by the domestic depleting crude oil resources. Focusing on alleviating the above-mentioned naphtha deficit, this paper puts forward an idea suggesting that China＇s limited naphtha resource should be used reasonably. Naphtha feedstocks with more potential aromatic content should be used in catalytic reforming process to produce clean fuel products, and those feedstocks with more paraffinic content should be used in ethylene production. Meanwhile, industry tests show that the low-valued naphtha byproduct from ethylene plants and the products of secondary processing units at refineries can also be applied so as to extend the naphtha supply for manufacture of cleaner fuels and ethylene derivatives.