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小额贷款公司发展面临的制度困境和策略研究 被引量:2
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作者 解宁 《时代金融》 2012年第10X期231-232,共2页
小额贷款公司拓宽了"三农"和小微企业的融资渠道,对于构建更加完善的金融贷款体系,增强其抵抗风险的能力都具有深远的意义。随着市场化改革的深入,小额贷款公司的发展面临严峻的制度困境。本文从小额贷款公司的现状出发,剖析... 小额贷款公司拓宽了"三农"和小微企业的融资渠道,对于构建更加完善的金融贷款体系,增强其抵抗风险的能力都具有深远的意义。随着市场化改革的深入,小额贷款公司的发展面临严峻的制度困境。本文从小额贷款公司的现状出发,剖析其所面临的制度困境,探寻解决这一系列制度困境的策略,从而使小额贷款公司更加稳健的发展。 展开更多
关键词 小额贷款公司 政策监管 双转制 供应链金融 联网式
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Comparison of two types of twin-rotor piston engine mechanisms 被引量:6
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作者 邓豪 潘存云 +2 位作者 王晓聪 张雷 邓力 《Journal of Central South University》 SCIE EI CAS 2013年第2期363-371,共9页
A novel twin-rotor piston engine (TRPE) mechanism with high volumetric output and power density was introduced. This new engine comprises an energy conversion system and a differential velocity drive mechanism (DVD... A novel twin-rotor piston engine (TRPE) mechanism with high volumetric output and power density was introduced. This new engine comprises an energy conversion system and a differential velocity drive mechanism (DVDM). Two special geared four-bar mechanisms, DVDM-1 and DVDM-2, were utilized and compared. Based on the closed loop vector method, a mathematical model for position, velocity, and acceleration of the two mechanisms was established. Numerical examples illustrate that the kinematic characteristics were presented. Expression of the displacement and compression ratio of the two engine mechanisms were derived and compared. It is concluded that both DVDM-1 and DVDM-2 adopted in the proposed TRPE with six vane pistons create thirty-six power strokes per revolution of the output shaft, and the summation of two angles covered by each rocker is always 2x/N as the output shaft rotates an angle of x/N. In DVDM-1, the span angle of a vane piston should be designed to be 10.2°, and the compression ratio should be equal to 10; in DVDM-2, the span angle of a vane piston should be designed to be 10.6°, and the compression ratio should be equal to 4.3. 展开更多
关键词 ROTOR piston engine CRANK ROCKER power density
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Temperature dependence of magnetization reversal mechanism in CoNi/CoO bilayers
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作者 宋金涛 袁淑娟 《Journal of Shanghai University(English Edition)》 CAS 2007年第6期562-565,共4页
Exchange coupling and magfietization reversal mechanism in two series of CoxNil-x/CoO (30 nm) (x=0.2 and 0.4) bilayers are studied by vector magnetometer. Two components of magnetization are measured parallel and ... Exchange coupling and magfietization reversal mechanism in two series of CoxNil-x/CoO (30 nm) (x=0.2 and 0.4) bilayers are studied by vector magnetometer. Two components of magnetization are measured parallel and perpendicular to the applied field. At low temperatures, coercivity Hc oc (tFM)^-n, n = 1.5 and 1.38 for x = 0.2 and 0.4, respectively, in agreement with the random field model. At room temperature, the coercivity is nearly proportional to the inverse FM layer thickness. In addition to the exchange field and the coercivity, the characteristic of the magnetization reversal mechanism was found to change with temperature. At temperatures below 180 K, magnetization reversal process along the unidirectional axis is accompanied only by nucleation and pinning of domain wall while magnetization rotation is also involved at high temperatures. 展开更多
关键词 exchange coupling BILAYER magnetization reversal temperature dependence.
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BEACON SYNCHRONIZATION TECHNOLOGY FOR “BEIDOU” TERRESTRIAL IMPROVEMENT SYSTEM 被引量:2
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作者 WEIJin-chen TANGJi-qiang SHENFeng 《Transactions of Nanjing University of Aeronautics and Astronautics》 EI 2005年第2期177-182,共6页
Synchronization is an essential technology in the radio navigation system. The technique for improving the “Beidou” positioning ability is presented through constituting the terrestrial improvement system, and the b... Synchronization is an essential technology in the radio navigation system. The technique for improving the “Beidou” positioning ability is presented through constituting the terrestrial improvement system, and the beacon synchronization of the improvement system with the “Beidou” one-way time transfer model is realized.The direct digital synthesis (DDS) is adopted to generate the pseudo-random code clock having high precision and stability. Meanwhile, the CPLD device is used to design the synchronization pulse picking-up module, the spread spectrum PN code generator and the spread spectrum modulator. Measurement results indicate that the beacon synchronization has the high precision and the stability. 展开更多
关键词 radio navigation system terrestrial improvement system time transfer SYNCHRONIZATION
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PRACTICAL ALGORITHMS FOR TORNADO CODES
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作者 Ai Da Chang Yilin +1 位作者 Luo Zhong Wang Jing 《Journal of Electronics(China)》 2006年第2期274-276,共3页
Tornado codes have been used in the error control of data transmission in IP network. The efficiency of this erasure codes is critically affected by the short cycles in its bipartite graph. To remove this effect, two ... Tornado codes have been used in the error control of data transmission in IP network. The efficiency of this erasure codes is critically affected by the short cycles in its bipartite graph. To remove this effect, two algorithms are introduced: (1) while generating the graph, the cycle eliminating algorithm is used to reduce the number of the short cycles in it; (2) in the decoding algorithm, cycles that are inevitably in the graph are used to remove decoding efficiency degradation. The simulation results show that they have a better performance than that of general tornado codes. 展开更多
关键词 Tornado code Bipartite graph Short cycle Erasure correcting efficiency
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Fuzzy-second order sliding mode control optimized by genetic algorithm applied in direct torque control of dual star induction motor 被引量:1
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作者 Ghoulemallah BOUKHALFA Sebti BELKACEM +1 位作者 Abdesselem CHIKHI Moufid BOUHENTALA 《Journal of Central South University》 SCIE EI CAS CSCD 2022年第12期3974-3985,共12页
The direct torque control of the dual star induction motor(DTC-DSIM) using conventional PI controllers is characterized by unsatisfactory performance, such as high ripples of torque and flux, and sensitivity to parame... The direct torque control of the dual star induction motor(DTC-DSIM) using conventional PI controllers is characterized by unsatisfactory performance, such as high ripples of torque and flux, and sensitivity to parametric variations. Among the most evoked control strategies adopted in this field to overcome these drawbacks presented in classical drive, it is worth mentioning the use of the second order sliding mode control(SOSMC) based on the super twisting algorithm(STA) combined with the fuzzy logic control(FSOSMC). In order to realize the optimal control performance, the FSOSMC parameters are adjusted using an optimization algorithm based on the genetic algorithm(GA). The performances of the envisaged control scheme, called G-FSOSMC, are investigated against G-SOSMC, G-PI and BBO-FSOSMC algorithms. The proposed controller scheme is efficient in reducing the torque and flux ripples, and successfully suppresses chattering. The effects of parametric uncertainties do not affect system performance. 展开更多
关键词 double star induction machine direct torque control fuzzy second order sliding mode control genetic algorithm biogeography based optimization algorithm
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Design, synthesis and activity evaluation of novel pyridinone derivatives as anti-HIV-1 dual(RT/IN) inhibitors 被引量:1
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作者 Quanzhi Yang Tao Sheng +7 位作者 Ningning Fan Yameng Hao Yuanyuan Cao Ying Guo Zhili Zhang Chao Tian Junyi Liu Xiaowei Wang 《Journal of Chinese Pharmaceutical Sciences》 CAS CSCD 2017年第1期31-44,共14页
Three series of novel anti-immunodeficiency virus 1 (HIV-1) dual (RT/1N) inhibitors were rationally designed by introducing a functioning diketo acid (DKA) into pyridin-2-one scaffold. To efficiently analyze inh... Three series of novel anti-immunodeficiency virus 1 (HIV-1) dual (RT/1N) inhibitors were rationally designed by introducing a functioning diketo acid (DKA) into pyridin-2-one scaffold. To efficiently analyze inhibitory activity, these compounds were screened against HIV-1 RT and IN respectively via surface plasmon resonance (SPR), and active compounds were subsequently evaluated by enzyme assay. It was noteworthy that compound A2 exhibited moderate activity against both HIV-1 RT and IN. This result provided information for further development of pyridinone analogues as potent dual HIV-1 inhibitors. 展开更多
关键词 Pyridinone derivatives HIV-1 dual inhibitor Reverse transcriptase INTEGRASE
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Bidirectional effect of Wnt signaling antagonist DKK1 on the modulation of anthrax toxin uptake 被引量:2
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作者 QIAN LiLi CAI ChangZu +7 位作者 YUAN PengFei JEONG Sun-Young YANG XiaoZhou DEALMEIDA Venita ERNST James COSTA Michael COHEN Stanley N. WEI WenSheng 《Science China(Life Sciences)》 SCIE CAS 2014年第5期469-481,共13页
LRP6, a co-receptor for the morphogen Wnt, aids endocytosis of anthrax complexes. Here we report that Dickkopfl (DKK1) protein, a secreted LRP6 ligand and antagonist, is also a modulator of anthrax toxin sensitivity... LRP6, a co-receptor for the morphogen Wnt, aids endocytosis of anthrax complexes. Here we report that Dickkopfl (DKK1) protein, a secreted LRP6 ligand and antagonist, is also a modulator of anthrax toxin sensitivity, shRNA-mediated gene silencing or TALEN-mediated gene knockout of DKK1 reduced sensitivity of cells to PA-dependent hybrid toxins. However, unlike the solely inhibitory effect on Wnt signaling, the effects of DKK1 overexpression on anthrax toxicity were bidirectional, depending on its endogenous expression and cell context. Fluorescence microscopy and biochemical analyses showed that DKK1 facilitates internalization of anthrax toxins and their receptors, an event mediated by DKK1-LRP6-Kremen2 complex. Monoclonal antibodies against DKK1 provided dose-dependent protection to macrophages from killing by anthrax lethal toxin (LT). Our discovery that DKK1 forms ternary structure with LRP6 and Kremen2 in promoting PA-mediated toxin internalization provides a paradigm for bacterial exploitation of mechanisms that host cells use to internalize signaling proteins. 展开更多
关键词 DKK1 anthrax toxin LRP6 TALENs INTERNALIZATION Kremen2 receptor WNT
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A novel copper-sensing two-component system for inducing Dsb gene expression in bacteria 被引量:1
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作者 Liang Yu Qiao Cao +6 位作者 Weizhong Chen Nana Yang Cai-Guang Yang Quanjiang Ji Min Wu Taeok Bae Lefu Lan 《Science Bulletin》 SCIE EI CSCD 2022年第2期198-212,M0004,共16页
In nature, bacteria must sense copper and tightly regulate gene expression to evade copper toxicity. Here,we identify a new copper-responsive two-component system named DsbRS in the important human pathogen Pseudomona... In nature, bacteria must sense copper and tightly regulate gene expression to evade copper toxicity. Here,we identify a new copper-responsive two-component system named DsbRS in the important human pathogen Pseudomonas aeruginosa;in this system, DsbS is a sensor histidine kinase, and DsbR, its cognate response regulator, directly induces the transcription of genes involved in protein disulfide bond formation(Dsb)(i.e., the dsbDEG operon and dsbB). In the absence of copper, DsbS acts as a phosphatase toward DsbR, thus blocking the transcription of Dsb genes. In the presence of copper, the metal ion directly binds to the sensor domain of DsbS, and the Cys82 residue plays a critical role in this process. The copperbinding behavior appears to inhibit the phosphatase activity of DsbS, leading to the activation of DsbR.The copper resistance of the dsbRS knock-out mutant is restored by the ectopic expression of the dsbDEG operon, which is a DsbRS major target. Strikingly, cognates of the dsbRS-dsbDEG pair are widely distributed across eubacteria. In addition, a DsbR-binding site, which contains the consensus sequence 5’-TTA-N8-TTAA-3’, is detected in the promoter region of dsbDEG homologs in these species. These findings suggest that the regulation of Dsb genes by DsbRS represents a novel mechanism by which bacterial cells cope with copper stress. 展开更多
关键词 Pseudomonas aeruginosa Two-component system Disulfide bond formation Gene regulation Copper resistance
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