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数量对合矩阵与数量反对合矩阵的迹与谱
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作者 陈梅香 杨忠鹏 高洁 《龙岩学院学报》 2024年第5期1-7,共7页
应用相似关系下保持特征值与迹不变的性质,避开了计算特征多项式,得到了数量对合矩阵和数量反对合矩阵的只用迹表示的谱、行列式的计算公式及其相似等价类。作为应用,得到了通常对合矩阵、反对合矩阵、对称正交矩阵和反对称正交矩阵的... 应用相似关系下保持特征值与迹不变的性质,避开了计算特征多项式,得到了数量对合矩阵和数量反对合矩阵的只用迹表示的谱、行列式的计算公式及其相似等价类。作为应用,得到了通常对合矩阵、反对合矩阵、对称正交矩阵和反对称正交矩阵的相关结论。 展开更多
关键词 特征值 数量对矩阵 数量反对合矩阵 正交矩阵
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反对合矩阵的相似对角化 被引量:4
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作者 黄益生 陈椰婷 《三明学院学报》 2013年第2期1-5,共5页
通过证明在复数域上每一个反对合矩阵都可以对角化,指出了全体n阶反对合矩阵按矩阵的相似关系进行分类,一共可以分成n+1类。还证明了,在实数域上不存在奇数阶反对合矩阵,并且每一个偶数阶反对合矩阵都不可对角化,但是每一个2n阶反对合... 通过证明在复数域上每一个反对合矩阵都可以对角化,指出了全体n阶反对合矩阵按矩阵的相似关系进行分类,一共可以分成n+1类。还证明了,在实数域上不存在奇数阶反对合矩阵,并且每一个偶数阶反对合矩阵都不可对角化,但是每一个2n阶反对合矩阵都相似于diag{J1,J2,…,Jn},这里Jk=(0 -1 1 0),k=1,2,…,n,因而全体2n阶反对合实矩阵按矩阵的相似关系进行分类,只有一种类型。同时,指出了每一个非零偶数维实线性空间上的反对合变换都有无穷多个。 展开更多
关键词 反对合矩阵 反对合变换 矩阵 相似关系 分类
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对合矩阵和反对合矩阵的若干性质 被引量:11
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作者 邹本强 《金华职业技术学院学报》 2007年第2期88-90,共3页
在高等代数中矩阵是研究问题很重要的工具,在讨论矩阵的乘法运算时给出了对合矩阵的定义,但对其性质研究很少.对合矩阵和反对合矩阵作为特殊矩阵无论在矩阵理论方面,还是在实际应用方面都有重要的意义.我们在研究矩阵及学习有关数学知识... 在高等代数中矩阵是研究问题很重要的工具,在讨论矩阵的乘法运算时给出了对合矩阵的定义,但对其性质研究很少.对合矩阵和反对合矩阵作为特殊矩阵无论在矩阵理论方面,还是在实际应用方面都有重要的意义.我们在研究矩阵及学习有关数学知识时,经常要讨论这两种特殊矩阵的性质.本文先给出对合矩阵和反对合矩阵的定义,然后讨论了它们的若干性质. 展开更多
关键词 矩阵 反对合矩阵 性质
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与反对合矩阵可交换的对合矩阵
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作者 黄益生 林巧珍 《龙岩学院学报》 2013年第2期9-13,共5页
讨论与反对合矩阵可交换的对合矩阵,主要结果如下:(1)与n阶反对合矩阵可交换的对合矩阵的一种表示;(2)对于2阶反对合矩阵A,如果A≠iI(I是单位矩阵),那么与A可交换的对合矩阵一共有4个,它们是±I和±iA;(3)对于3阶反对合矩阵A,如... 讨论与反对合矩阵可交换的对合矩阵,主要结果如下:(1)与n阶反对合矩阵可交换的对合矩阵的一种表示;(2)对于2阶反对合矩阵A,如果A≠iI(I是单位矩阵),那么与A可交换的对合矩阵一共有4个,它们是±I和±iA;(3)对于3阶反对合矩阵A,如果A≠iI,那么与A可交换的全体对合矩阵为±I和±iA以及±P11k-1P-1,±P-11k-1P-1,P1k l1-k2l-kP-1,P-1k l1-k2l-kP-1其中k是任意复数,l是任意非零复数;当tr(A)=-i时,P是A与diag{i,-i,-i}这一对相似矩阵之间的一个相似因子;当tr(A)=i时,P是A与diag{-i,i,i}之间的一个相似因子。 展开更多
关键词 矩阵 反对合矩阵 矩阵的相似关系 特征值
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与对合矩阵可交换的反对合矩阵 被引量:2
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作者 王洁 黄益生 《三明学院学报》 2013年第4期7-12,共6页
讨论与对合矩阵可交换的反对合矩阵。主要结果如下:(1)给出了与n阶对合矩阵可交换的反对合矩阵的一种表示;(2)对于2阶对合矩阵A,如果A≠±I(I是单位矩阵),那么与A可交换的反对合矩阵一共有4个,它们是±iI和±iA;(3)对于3阶... 讨论与对合矩阵可交换的反对合矩阵。主要结果如下:(1)给出了与n阶对合矩阵可交换的反对合矩阵的一种表示;(2)对于2阶对合矩阵A,如果A≠±I(I是单位矩阵),那么与A可交换的反对合矩阵一共有4个,它们是±iI和±iA;(3)对于3阶对合矩阵A,如果A≠±I,那么与A可交换的全体反对合矩阵为±iI和±iA,以及■其中k是任意复数,l是任意非零复数;当tr(A)=-1时,P是A与diag{1,-1,-1}这一对相似矩阵之间的相似因子;当tr(A)=1时,P是A与diag{-1,1,1}之间的相似因子。 展开更多
关键词 矩阵 反对合变换 矩阵的相似关系 特征值
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与四阶对合矩阵可交换的反对合矩阵
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作者 林冰雁 李宾 王燕如 《乐山师范学院学报》 2015年第4期18-20,共3页
讨论与四阶对合矩阵可交换的反对合矩阵。主要结果如下:对于四阶对合矩阵A,如果A≠±I(I是单位矩阵),那么与A可交换的全体反对合矩阵可以分为四类:±i I、±i A、tr(A)=±2和tr(A)=0。
关键词 反对合矩阵 矩阵 相似因子
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温度对T700/3234反对称铺设圆柱壳结构的双稳态特性影响 被引量:1
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作者 张征 潘豪 +3 位作者 叶钢飞 李琛 吴化平 柴国钟 《航空材料学报》 EI CAS CSCD 北大核心 2016年第5期70-76,共7页
讨论温度对T700/3234反对称铺设圆柱壳结构的双稳态特性的影响。通过热压固化成型工艺制备了三种不同铺层层数的试样,采用两点加载的方式,使用在现有的拉伸试验机上改装的实验测试平台驱动反对称铺设圆柱壳结构进行稳态转变,持续捕捉实... 讨论温度对T700/3234反对称铺设圆柱壳结构的双稳态特性的影响。通过热压固化成型工艺制备了三种不同铺层层数的试样,采用两点加载的方式,使用在现有的拉伸试验机上改装的实验测试平台驱动反对称铺设圆柱壳结构进行稳态转变,持续捕捉实验过程中的数据,得到在20℃,40℃,60℃和80℃温度下的载荷—位移曲线的变化规律及稳态转变载荷。实验后,通过图像处理技术得到曲率和扭曲率等数据。系统分析稳态转变载荷和稳态曲率变化情况,并对存放时间对壳结构的影响进行了讨论。结果表明,温度对双稳态结构稳态转变影响较大,给出了温度对snap-through和snap-back过程的影响规律。 展开更多
关键词 碳纤维复材料 反对称层 双稳态特性 温度场
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欧氏空间R_s^n上的三种变换 被引量:1
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作者 赵巧玲 《宝鸡文理学院学报(自然科学版)》 CAS 2002年第1期41-42,共2页
讨论了R_s^n上的反自共轭变换 。
关键词 反自共轭变换 反对合变换 正交变换 欧氏空间 正定对称矩阵 矩阵变换
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广义Hamiltonian矩阵反问题及其迭代算法
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作者 梁开福 韩长江 《湘潭大学自然科学学报》 CAS 北大核心 2013年第1期6-10,共5页
利用矩阵的分解技术,研究了线性矩阵方程AW=B存在反Hermitian广义Hamiltonian解的充分必要条件,并给出了其解的一般表示形式;然后,给出了该矩阵方程在实数域内反对称广义Hamiltonian解的迭代方法,在不考虑计算误差的情况下,经过有限步迭... 利用矩阵的分解技术,研究了线性矩阵方程AW=B存在反Hermitian广义Hamiltonian解的充分必要条件,并给出了其解的一般表示形式;然后,给出了该矩阵方程在实数域内反对称广义Hamiltonian解的迭代方法,在不考虑计算误差的情况下,经过有限步迭代,可以得到实反对称广义Hamiltonian解. 展开更多
关键词 矩阵方程 反问题 Hamiltonian矩阵 迭代方法 反对合
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保持交换环上两类矩阵运算的映射 被引量:1
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作者 王雨轩 霍东华 《高等数学研究》 2022年第1期49-53,56,共6页
主要针对交换环上两类矩阵的保持问题进行展开:(1)刻画了交换环上全矩阵空间和上三角形矩阵空间的保持反对合矩阵映射的形式.(2)研究了交换环上n阶上三角形矩阵空间的保持伴随矩阵映射的形式.
关键词 全矩阵 上三角矩阵 反对合矩阵 伴随矩阵 保持问题
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New criterion for delay-dependent absolute stability of Lurie system with interval time-varying delay 被引量:1
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作者 薛明香 费树岷 +1 位作者 李涛 潘俊涛 《Journal of Southeast University(English Edition)》 EI CAS 2011年第4期375-378,共4页
The delay-dependent absolute stability for a class of Lurie systems with interval time-varying delay is studied. By employing an augmented Lyapunov functional and combining a free-weighting matrix approach and the rec... The delay-dependent absolute stability for a class of Lurie systems with interval time-varying delay is studied. By employing an augmented Lyapunov functional and combining a free-weighting matrix approach and the reciprocal convex technique, an improved stability condition is derived in terms of linear matrix inequalities (LMIs). By retaining some useful terms that are usually ignored in the derivative of the Lyapunov function, the proposed sufficient condition depends not only on the lower and upper bounds of both the delay and its derivative, but it also depends on their differences, which has wider application fields than those of present results. Moreover, a new type of equality expression is developed to handle the sector bounds of the nonlinear function, which achieves fewer LMIs in the derived condition, compared with those based on the convex representation. Therefore, the proposed method is less conservative than the existing ones. Simulation examples are given to demonstrate the validity of the approach. 展开更多
关键词 Lurie system reciprocal convex technique absolute stability interval time-varying delay linear matrix inequality (LMI)
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Kinetic study on reactive extraction of phenylalanine enantiomers with BINAP-copper complexes 被引量:1
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作者 唐课文 罗菁菁 +3 位作者 张盼良 易健民 华杰 杨长安 《Chinese Journal of Chemical Engineering》 SCIE EI CAS CSCD 2015年第1期57-63,共7页
Enantioselective liquid–liquid extraction has attracted considerable attention for its potential use in largescale production. Kinetic data are needed for the reliable scale-up of the process. This paper reports the ... Enantioselective liquid–liquid extraction has attracted considerable attention for its potential use in largescale production. Kinetic data are needed for the reliable scale-up of the process. This paper reports the kinetic study of reactive extraction of phenylalanine(Phe) enantiomers with BINAP–copper complex(BINAP–Cu) as a chiral selector. The theory of extraction accompanied by a chemical reaction was applied.The effects of agitation speed, interfacial area, p H value of aqueous phase, initial concentration of Phe enantiomers and initial concentration of BINAP–Cu on the specific rate of extraction were investigated. The forward rate constants of the reactions in the reactive extraction process are 7.93 × 10-5m5/2·mol-1/2·s-1for D-Phe and 1.29 × 10-4m5/2·mol-1/2·s-1for L-Phe. 展开更多
关键词 KINETICS Amino acids Modeling Liquid–liquid extraction ENANTIOMERS
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Characterization of Bioaerosol Bacterial Communities During Hazy and Foggy Weather in Qingdao, China 被引量:2
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作者 QI Jianhua LI Mengzhe +1 位作者 ZHEN Yu WU Lijing 《Journal of Ocean University of China》 SCIE CAS CSCD 2018年第3期516-526,共11页
This study was conducted to evaluate the impact of hazy and foggy weather on the bacterial communities in bioaerosols, for which samples were collected from the Qingdao coastal region on sunny, foggy, and hazy days in... This study was conducted to evaluate the impact of hazy and foggy weather on the bacterial communities in bioaerosols, for which samples were collected from the Qingdao coastal region on sunny, foggy, and hazy days in January and March 2013. Bacterial community compositions were determined using polymerase chain reaction denaturing gradient gel electrophoresis(PCR-DGGE). The bacterial community diversity was found to be high on foggy and hazy days, and the dominant species differed during hazy weather. The Shannon-Wiener index revealed that the bacterial community diversity of coarse particles was higher than that of fine particles in the bioaerosols. The bacterial community diversity of fine particles significantly correlated with relative humidity(RH; r^2 = 0.986). The cluster analysis results indicated that the bacterial communities on sunny days differed from those on hazy and foggy days. Compared with sunny days, the bacterial communities in the fine particles during hazy weather exhibited greater changes than those in the coarse particles. Most of the sequenced bacteria were found to be closely affiliated with uncultured bacteria. During hazy weather, members of the classes Bacilli and Gammaproteobacteria(Pseudomonas and Acinetobacter) were dominant. The DGGE analysis revealed that Proteobacteria and Firmicutes were the predominant phyla, and their relative percentages to all the measured species changed significantly on hazy days, particularly in the fine particles. Haze and fog had a significant impact on the bacterial communities in bioaerosols, and the bacterial community diversity varied on different hazy days. 展开更多
关键词 bacterial community BIOAEROSOLS HAZE FOG Qingdao
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A rapid and sensitive method to detect mycobacterium tuberculosis DNA by fluorescence polarization 被引量:1
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作者 白玉杰 赵锦荣 +4 位作者 薛丽 刘爱翔 张文红 郭晏海 闫小君 《Journal of Medical Colleges of PLA(China)》 CAS 2004年第4期219-221,共3页
Objective: To develop a new high sensitivity, rapid and simple mycobacterium tuberculosis DNA detection method using fluorescence polarization technology. Methods: In our asymmetric PCR protocol, 100 times mole of TB-... Objective: To develop a new high sensitivity, rapid and simple mycobacterium tuberculosis DNA detection method using fluorescence polarization technology. Methods: In our asymmetric PCR protocol, 100 times mole of TB-R primer was added than in the usual symmetric PCR to get enough single strands PCR product. The probe TB-5′-TAMRA and PCR products were mixed in a tube and incubate for 5-15 min at 46 ℃.The polarization (mp) was measured using victor2 Multilabel Plate Reader. Results: Asymmetric and symmetric PCR products were analyzed by the FP method. Asymmetric PCR products are detected more sensitively than symmetric ones. The polarization values of probe associated with asymmetric products were much higher than with symmetric products. Conclusion: This fluorescence polarization assay in conjunction with asymmetric PCR is a powerful and widely applicable method for the rapid and sensitive detection of micro-organisms in clinical laboratories. 展开更多
关键词 mycobacterium tuberculosis asymmetric polymerase chain reaction fluorescence polarization
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Analytical Solutions to the Fundamental Frequency of Arbitrary Laminated Plates under Various Boundary Conditions 被引量:1
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作者 Yingqin Luo Ming Hong Yuan Liu 《Journal of Marine Science and Application》 CSCD 2015年第1期46-52,共7页
In recent years, as the composite laminated plates are widely used in engineering practice such as aerospace, marine and building engineering, the vibration problem of the composite laminated plates is becoming more a... In recent years, as the composite laminated plates are widely used in engineering practice such as aerospace, marine and building engineering, the vibration problem of the composite laminated plates is becoming more and more important. Frequency, especially the fundamental frequency, has been considered as an important factor in vibration problem. In this paper, a calculation method of the fundamental frequency of arbitrary laminated plates under various boundary conditions is proposed. The vibration differential equation of the laminated plates is established at the beginning of this paper and the frequency formulae of specialty orthotropic laminated plates under various boundary conditions and antisymmetric angle-ply laminated plates with simply-supported edges are investigated. They are proved to be correct. Simple algorithm of the fundamental frequency for multilayer antisymmetric and arbitrary laminated plates under various boundary conditions is studied by a series of typical examples. From the perspective of coupling, when the number of laminated plates layers N〉8-10, some coupling influence on the fundamental frequency can be neglected. It is reasonable to use specialty orthotropic laminated plates with the same thickness but less layers to calculate the corresponding fundamental frequency of laminated plates. Several examples are conducted to prove correctness of this conclusion. At the end of this paper, the influence of the selected number of layers of specialty orthotropic laminates on the fundamental frequency is investigated. The accuracy and complexity are determined by the number of layers. It is necessary to use proper number of layers of special orthotropic laminates with the same thickness to simulate the fundamental frequency in different boundary conditions. 展开更多
关键词 laminated plates arbitrary orientation analytical solutions fundamental frequency boundary conditions
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Expression profiles of antimicrobial peptides (AMPs) and their regulation by Relish 被引量:2
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作者 王冬冬 李富花 +2 位作者 李诗豪 温荣 相建海 《Chinese Journal of Oceanology and Limnology》 SCIE CAS CSCD 2012年第4期611-619,共9页
Antimicrobial peptides (AMPs), as key immune effectors, play important roles in the innate immune system of invertebrates. Different types of AMPs, including Penaeidin, Crustin, ALF (anti- lipopolysaccharide factor... Antimicrobial peptides (AMPs), as key immune effectors, play important roles in the innate immune system of invertebrates. Different types of AMPs, including Penaeidin, Crustin, ALF (anti- lipopolysaccharide factor) have been identified in different penaeid shrimp; however, systematic analyses on the function of different AMPs in shrimp responsive to different types of bacteria are very limited. In this study, we analyzed the expression profiles of AMPs in the Chinese shrimps, Fenneropenaeus chinensis, simultaneously by real-time RT-PCR (reverse transcription-polymerase chain reaction) when shrimp were challenged with Micrococcus lysodeikticus (Gram-positive, G+) or Hbrio anguillarium (Gram-negative, G-). Different AMPs showed different expression profiles when shrimp were injected with one type of bacterium, and one AMP also showed different expression profiles when shrimp were challenged with different bacteria. Furthermore, the expression of these AMPs showed temporal expression profiles, suggesting that different AMPs function coordinately in bacteria-infected shrimp. An RNA interference approach was used to study the function of the Relish transcription factor in regulating the transcription of different AMPs. The current study showed that Relish could regulate the transcription of different AMPs in shrimp. Differential expression profiles of AMPs in shrimp injected with different types of bacteria indicated that a complicated antimicrobial response network existed in shrimp. These data contribute to our understanding of immunity in shrimp and may provide a strategy for the control of disease in shrimp. 展开更多
关键词 antimicrobial peptides (AMPs) expression profiles BACTERIA Relish RNA interference
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Ku80 gene G-1401T promoter polymorphism and risk of gastric cancer 被引量:1
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作者 Jia-Qi Li Jie Chen +4 位作者 Nan-Nan Liu Li Yang Ying Zeng Bin Wang Xue-Rong Wang 《World Journal of Gastroenterology》 SCIE CAS CSCD 2011年第16期2131-2136,共6页
AIM:To evaluate the possible relationship between the Ku80 gene polymorphism and the risk of gastric cancer in China.METHODS:In this hospital-based case-control study of gastric cancer in Jiangsu Province,China,we inv... AIM:To evaluate the possible relationship between the Ku80 gene polymorphism and the risk of gastric cancer in China.METHODS:In this hospital-based case-control study of gastric cancer in Jiangsu Province,China,we investigated the association of the Ku80 G-1401T (rs828907) polymorphism with gastric cancer risk.A total of 241 patients with gastric cancer and 273 age-and sexmatched control subjects were genotyped and analyzed by polymerase chain reaction-restriction fragment length polymorphism.RESULTS:The frequencies of genotypes GG,GT and TT were 65.6%,22.8% and 11.6% in gastric cancer cases,respectively,and 75.8%,17.6% and 6.6% in controls,respectively.There were significant differences between gastric cancer and control groups in the distribution of their genotypes (P=0.03) and allelic frequencies (P=0.002) in the Ku80 promoter G-1401T polymorphism.CONCLUSION:The T allele of Ku80 G-1401T may be associated with the development of gastric cancer. 展开更多
关键词 KU80 Gastric cancer POLYMORPHISM PROMOTER CARCINOGENESIS
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The Asymmetric Response of Older Male Labour Force Participation Rates to Pension Reform and Labour Market Variables 被引量:2
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作者 Martin O'Brien 《Journal of Modern Accounting and Auditing》 2011年第4期358-367,共10页
Increasing the labour force participation rates of older workers is a fundamental component of most OECD (Organization for Economic Cooperation and Development) countries' response to the fiscal pressures associate... Increasing the labour force participation rates of older workers is a fundamental component of most OECD (Organization for Economic Cooperation and Development) countries' response to the fiscal pressures associated with ageing populations. Both pension reform and employment policies are key elements to achieving such increases in participation and reversing the early retirement trends of recent decades. Econometric modeling results from a panel of 12 OECD countries indicate that labour market variables have a greater influence than social security pension value or the standard age of retirement on the labour force participation rates of males aged 55-64 years. Further results from modeling the potential asymmetric response of participation rates to unemployment rates indicate that a decrease in unemployment rates has a greater impact upon increasing the labour force participation rates of older workers compared to the effect of an increase on unemployment rates has on discouraging participation. We found mixed results for the asymmetric response of participation to an increase or decrease in pension value. Findings thus emphasize the importance of labour market oriented policies to reduce unemployment rates in the developed economies in coming years to address ageing population concerns. 展开更多
关键词 older workers labour force participation discouraged workers
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Signal transduction mechanism of TRB3 in rats with non-alcoholic fatty liver disease 被引量:5
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作者 Yu-Gang Wang Min Shi +4 位作者 Ting Wang Ting Shi Jue Wei Na Wang Xi-Mei Chen 《World Journal of Gastroenterology》 SCIE CAS CSCD 2009年第19期2329-2335,共7页
AIM: To evaluate the possible role of Tribble 3 (TRB3) in a rat model of non-alcoholic fatty liver disease (NAFLD) and its signal transduction mechanism.METHODS: Thirty Sprague-Dawley rats were randomized into t... AIM: To evaluate the possible role of Tribble 3 (TRB3) in a rat model of non-alcoholic fatty liver disease (NAFLD) and its signal transduction mechanism.METHODS: Thirty Sprague-Dawley rats were randomized into three groups: normal control group, non-alcoholic fatty liver group A (fed on a high-fat diet for 8 wk) and group B (fed on a high-fat diet for 16 wk). To determine the degree of hepatic steatosis in rats of each group, livers were stained with hematoxylin and eosin, and evaluated; real-time fluorescent quantitative reverse transcriptase-polymerase chain reaction was performed to measure the expression levels of TRI33 mRNA, and Western blotting analysis was done to determine the expression levels of protein kinase B (Akt) and phosphorylated protein kinase B (p-Akt-Thr308, p-Akt-Ser473).RESULTS: Hepatic steatosis was evident in both NAFLD groups: mild to moderate hepatic steatosis occurred in group A, mainly as mild steatosis.Moderate to severe hepatic steatosis occurred in group B, mainly as severe steatosis. The expression level of TRB3 mRNA in group B was significantly higher than in the control group (122.28 ± 95.37 vs 3.06 ± 2.33,P = 0.002) and group A (122.28 ± 95.37 vs 5.77 ± 4.20,P = 0.001). There was no significant difference in the expression levels of Akt (1.03 ± 0.53 vs 1.12 ± 0.77,P = 0.729) and p-Akt-Thr308 (0.82 ± 0.45 vs 0.92 ± 0.38, P = 0.592) between group A and the control group. The expression level of Akt and p-Akt-Thr308 in group B was significantly lower than in group A (Akt 0.41 ± 0.16 vs 1.12 ± 0.77, P = 0.008; p-Akt-Thr308 0.47 ± 0.19 vs 0.82 ± 0.45, P = 0.036) and the control group (Akt 0.41 ± 0.16 vs 1.03 ± 0.53, P = 0.018;p-Akt-Thr308 0.47 ± 0.19 vs 0.92 ± 0.38, P = 0.010).The expression level of p-Akt-Ser473 in group A was significantly higher than in group B (1.48 ± 0.50 vs 0.81± 0.39, P = 0.041) as well as the control group (1.48 ± 0.50 vs 0.45 ± 0.26, P = 0.003).CONCLUSION: TRB3 blocks insulin signaling by inhibiting Akt activation, which contributes to insulin resistance. It may be an important factor in the occurrence and development of NAFLD. 展开更多
关键词 Non-alcoholic fatty liver disease Rat Tribble 3 Protein Kinase B Insulin resistance
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Asymmetric Total Synthesis towards the Simplified Analogs of Antibiotic Elansolid A
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作者 Yang Shuai Wu Jie Wang Liangliang 《有机化学》 SCIE CAS CSCD 北大核心 2024年第7期2350-2362,共13页
Natural product elansolid A belongs to one type of polyketide macrolactone with promising antibiotic activity.Pre-viously,the first total synthesis of elansolid A in 28 longest linear sequence(LLS)and 41 steps in tota... Natural product elansolid A belongs to one type of polyketide macrolactone with promising antibiotic activity.Pre-viously,the first total synthesis of elansolid A in 28 longest linear sequence(LLS)and 41 steps in total has been achieved.Herein,the simplified analog of elansolid A,featured with a cyclohexyl-fused 19-memebered macrolactone,was proposed,and its asymmetric total synthesis based on a convergent strategy and key reactions exemplified by desymmetric alcoholysis of anhydride,Pd-catalyzed Stille coupling,Suzuki-Miyaura coupling as well as Mukaiyama macrolactonization was finished. 展开更多
关键词 asymmetric total synthesis coupling reaction simplified analog elansolid A
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