Stem rust, caused by Puccinia graminis Pers. f. sp. tritici Eriks ＆ E. Henn., is an important disease of wheat （Triticum aestivum L.） in many countries. To estimate grain yield losses due race Ug99 （TTKSK）, repli...Stem rust, caused by Puccinia graminis Pers. f. sp. tritici Eriks ＆ E. Henn., is an important disease of wheat （Triticum aestivum L.） in many countries. To estimate grain yield losses due race Ug99 （TTKSK）, replicated experiments including fifteen wheat cultivars were screened for seedling and adult plant resistance. Greenhouse seedling test was conducted under controlled conditions. Field experiments were set up at two locations, Mau-Narok and KARI-Njoro, during 2008 and 2009 cropping seasons. The stem rust epidemics were created by inoculating spreader rows of a susceptible variety planted perpendicular to rows of non-protected plots. Rust severity and infection response were determined using modified Cobb scale. All the cultivars were susceptible at seedling stage, but some displayed adult plant resistance response despite of the high disease pressure. Mean grain yield losses ranged between 5.6% and 66.3% and were highly correlated to final disease severity （FDS） and the area under disease progress curve （AUDPC）. Genetic studies are needed to characterise the adult plant resistance in tolerant culti（,ars to race Ug99 for exploitation in breeding for resistance.展开更多
为了检测核电站反应堆控制棒组件,保障核电站在役检查顺利实施、降低检测成本。对反应堆控制棒组件(RCCA)检测用超声探头进行自主研制,本文详细介绍了15 MHz-Φ4 mm-FP8 mm RCCA超声探头制作流程,通过对压电晶片、声透镜、背衬3方面详...为了检测核电站反应堆控制棒组件,保障核电站在役检查顺利实施、降低检测成本。对反应堆控制棒组件(RCCA)检测用超声探头进行自主研制,本文详细介绍了15 MHz-Φ4 mm-FP8 mm RCCA超声探头制作流程,通过对压电晶片、声透镜、背衬3方面详细介绍探头制作工艺。通过对超声探头进行性能测试,测试脉冲周期数为1.5周,频带宽度为105%,在高温环境下仍能保持优良性能。对超声探头进行模拟检验测试,缺陷测试结果清晰可见,满足检验需求,可完全实现国产化替代进口产品。展开更多
HPR1000 is an advanced nuclear power plant(NPP)with the significant feature of an active and passive safety design philosophy,developed by the China National Nuclear Corporation.On one hand,it is an evolutionary desig...HPR1000 is an advanced nuclear power plant(NPP)with the significant feature of an active and passive safety design philosophy,developed by the China National Nuclear Corporation.On one hand,it is an evolutionary design based on proven technology of the existing pressurized water reactor NPP;on the other hand,it incorporates advanced design features including a 177-fuel-assembly core loaded with CF3 fuel assemblies,active and passive safety systems,comprehensive severe accident prevention and mitigation measures,enhanced protection against external events,and improved emergency response capability.Extensive verification experiments and tests have been performed for critical innovative improvements on passive systems,the reactor core,and the main equipment.The design of HPR1000fulfills the international utility requirements for advanced light water reactors and the latest nuclear safety requirements,and addresses the safety issues relevant to the Fukushima accident.Along with its outstanding safety and economy,HPR1000 provides an excellent and practicable solution for both domestic and international nuclear power markets.展开更多
In the SILER （Seismic-Initiated events risk mitigation in LEad-cooled Reactors） Project, it is interesting to apply seismic isolation technology for the reactor assembly of the fixed base reactor building for ADS （...In the SILER （Seismic-Initiated events risk mitigation in LEad-cooled Reactors） Project, it is interesting to apply seismic isolation technology for the reactor assembly of the fixed base reactor building for ADS （Acceleration Driven System） heavy liquid reactor MYRRHA （Multipurpose Hybrid Research Reactor for High-Tech Application） which contains the most critical safety related components, such as reactor vessel, safe shutdown and control rod mechanisms, primary heat exchangers, primary pumps, spoliation target assembly and fuel assemblies, etc. The purpose of this paper is to investigate the possibility of an application of a partial seismic isolation to the safety critical components only, here, the reactor assembly. This paper presents the preliminary analysis results of the isolated reactor assembly and compares these with those of seismic isolated ADS reactor building. The analysis results show the reduction of the seismic acceleration response but the increase of the relative displacement for the reactor assembly. Some safety issues, especially, coolant＇s incapable covering the reactor core make difficult to apply for the partial seismic isolation of the ADS reactor assembly due to large relative displacement occurring the partial isolation system. Further study on the partial seismic isolation application of the critical safety components are also discussed.展开更多
It is discovered a new three-, four-component Petasis, Passerini, Hantzsch, Kabachnic-Fields, Ugi reactions with of arsine, stibine and bismuthine in organometallic chemistry. Modifications were replaced to a nitrogen...It is discovered a new three-, four-component Petasis, Passerini, Hantzsch, Kabachnic-Fields, Ugi reactions with of arsine, stibine and bismuthine in organometallic chemistry. Modifications were replaced to a nitrogen atom of classical reactions of atoms of phosphorus, arsenic, antimony and bismuth. It has been proposed a new mechanism for possible reactions.展开更多
Computer simulation is a good guide and reference for development and research on petroleum refining processes. Traditionally, pseudo-components are used in the simulation, in which their physical properties are estim...Computer simulation is a good guide and reference for development and research on petroleum refining processes. Traditionally, pseudo-components are used in the simulation, in which their physical properties are estimated by empirical relations and cannot be associated with actual chemical reactions, as no molecular structure is available for pseudo-components. This limitation can be overcome if real components are used. In this paper, a real component based method is proposed for the simulation of a diesel hydrotreating process by using the software of Unisim Design. This process includes reaction units and distillation units. The chemical reaction network is established by analyzing the feedstock. The feedstock is characterized by real components, which are obtained based on true boiling point curve. Simulation results are consistent with actual data.展开更多
OBJECTIVE:To study the anaphylaxis of Qingkailing injection(QI) and its components.METHODS:Experimental anaphylactoid and allergic reactions were used.Changes in the behaviors of Beagles and serum levels of histamine,...OBJECTIVE:To study the anaphylaxis of Qingkailing injection(QI) and its components.METHODS:Experimental anaphylactoid and allergic reactions were used.Changes in the behaviors of Beagles and serum levels of histamine,immunoglobulin(Ig)E,IgG,IgM,eosinophil cationic protein(ECP),and interleukin(IL)-4,as well as blood pressure,after injecting QI and its components on the forelimb veins of Beagles were observed.RESULTS:According to comprehensive determination of abnormal behavior scores and changes in serum levels of histamine,IgE,IgG,IgM,ECP,and IL-4,as well as in blood pressure,radix isatidis and hyodeoxycholic acid caused anaphylactoid reactions,and honeysuckle,radix isatidis,hydrolysate,cholic acid and Gardenia jasminoides caused allergic reactions.The anaphylaxis of QI involved anaphylactoid and allergic reactions.CONCLUSION:QI and its components need to be refined further to improve the safety,efficacy,and quality of its use in clinical settings.展开更多
Activating transcription factor 5(ATF5) is a member of the activating transcription factor/cA MP response element binding protein(ATF/CREB) family, and is highly expressed in liver and adipose tissue. Previous reports...Activating transcription factor 5(ATF5) is a member of the activating transcription factor/cA MP response element binding protein(ATF/CREB) family, and is highly expressed in liver and adipose tissue. Previous reports have shown that ATF5 promoted 3T3-L1 preadipocytes differentiation. In this study, we found that ATF5 was highly expressed in mature adipocytes, suggesting a potential role of ATF5 in mature adipocytes, which has not been reported previously. To understand the function of ATF5 in mature adipocytes, we knocked down the expression of ATF5 in 3T3-L1 mature adipocytes and observed decreased lipid droplets. Consistent with the in vitro experiment, the knockdown of ATF5 in white adipose tissue led to less adipose tissue and smaller adipocytes size. Further research revealed that the inhibition of ATF5 diminished the adipocytes size via the inhibition of fatty acid synthetase, stearyl coenzyme A desaturation enzyme 1, and the induction of carnitine palmitoyl transferase 1, one key enzyme of lipid metabolism. In addition, ATF5 knockdown in inguinal white adipose tissue improved whole body insulin sensitivity.Our work provides a new understanding of ATF5 function in mature adipocytes and a potential therapeutic target of diabetes.展开更多
文摘Stem rust, caused by Puccinia graminis Pers. f. sp. tritici Eriks ＆ E. Henn., is an important disease of wheat （Triticum aestivum L.） in many countries. To estimate grain yield losses due race Ug99 （TTKSK）, replicated experiments including fifteen wheat cultivars were screened for seedling and adult plant resistance. Greenhouse seedling test was conducted under controlled conditions. Field experiments were set up at two locations, Mau-Narok and KARI-Njoro, during 2008 and 2009 cropping seasons. The stem rust epidemics were created by inoculating spreader rows of a susceptible variety planted perpendicular to rows of non-protected plots. Rust severity and infection response were determined using modified Cobb scale. All the cultivars were susceptible at seedling stage, but some displayed adult plant resistance response despite of the high disease pressure. Mean grain yield losses ranged between 5.6% and 66.3% and were highly correlated to final disease severity （FDS） and the area under disease progress curve （AUDPC）. Genetic studies are needed to characterise the adult plant resistance in tolerant culti（,ars to race Ug99 for exploitation in breeding for resistance.
文摘为了检测核电站反应堆控制棒组件,保障核电站在役检查顺利实施、降低检测成本。对反应堆控制棒组件(RCCA)检测用超声探头进行自主研制,本文详细介绍了15 MHz-Φ4 mm-FP8 mm RCCA超声探头制作流程,通过对压电晶片、声透镜、背衬3方面详细介绍探头制作工艺。通过对超声探头进行性能测试,测试脉冲周期数为1.5周,频带宽度为105%,在高温环境下仍能保持优良性能。对超声探头进行模拟检验测试,缺陷测试结果清晰可见,满足检验需求,可完全实现国产化替代进口产品。
文摘HPR1000 is an advanced nuclear power plant(NPP)with the significant feature of an active and passive safety design philosophy,developed by the China National Nuclear Corporation.On one hand,it is an evolutionary design based on proven technology of the existing pressurized water reactor NPP;on the other hand,it incorporates advanced design features including a 177-fuel-assembly core loaded with CF3 fuel assemblies,active and passive safety systems,comprehensive severe accident prevention and mitigation measures,enhanced protection against external events,and improved emergency response capability.Extensive verification experiments and tests have been performed for critical innovative improvements on passive systems,the reactor core,and the main equipment.The design of HPR1000fulfills the international utility requirements for advanced light water reactors and the latest nuclear safety requirements,and addresses the safety issues relevant to the Fukushima accident.Along with its outstanding safety and economy,HPR1000 provides an excellent and practicable solution for both domestic and international nuclear power markets.
文摘In the SILER （Seismic-Initiated events risk mitigation in LEad-cooled Reactors） Project, it is interesting to apply seismic isolation technology for the reactor assembly of the fixed base reactor building for ADS （Acceleration Driven System） heavy liquid reactor MYRRHA （Multipurpose Hybrid Research Reactor for High-Tech Application） which contains the most critical safety related components, such as reactor vessel, safe shutdown and control rod mechanisms, primary heat exchangers, primary pumps, spoliation target assembly and fuel assemblies, etc. The purpose of this paper is to investigate the possibility of an application of a partial seismic isolation to the safety critical components only, here, the reactor assembly. This paper presents the preliminary analysis results of the isolated reactor assembly and compares these with those of seismic isolated ADS reactor building. The analysis results show the reduction of the seismic acceleration response but the increase of the relative displacement for the reactor assembly. Some safety issues, especially, coolant＇s incapable covering the reactor core make difficult to apply for the partial seismic isolation of the ADS reactor assembly due to large relative displacement occurring the partial isolation system. Further study on the partial seismic isolation application of the critical safety components are also discussed.
文摘It is discovered a new three-, four-component Petasis, Passerini, Hantzsch, Kabachnic-Fields, Ugi reactions with of arsine, stibine and bismuthine in organometallic chemistry. Modifications were replaced to a nitrogen atom of classical reactions of atoms of phosphorus, arsenic, antimony and bismuth. It has been proposed a new mechanism for possible reactions.
文摘Computer simulation is a good guide and reference for development and research on petroleum refining processes. Traditionally, pseudo-components are used in the simulation, in which their physical properties are estimated by empirical relations and cannot be associated with actual chemical reactions, as no molecular structure is available for pseudo-components. This limitation can be overcome if real components are used. In this paper, a real component based method is proposed for the simulation of a diesel hydrotreating process by using the software of Unisim Design. This process includes reaction units and distillation units. The chemical reaction network is established by analyzing the feedstock. The feedstock is characterized by real components, which are obtained based on true boiling point curve. Simulation results are consistent with actual data.
基金Supported by National Science and Technology Major Projects(No.2010ZX09502-002)
文摘OBJECTIVE:To study the anaphylaxis of Qingkailing injection(QI) and its components.METHODS:Experimental anaphylactoid and allergic reactions were used.Changes in the behaviors of Beagles and serum levels of histamine,immunoglobulin(Ig)E,IgG,IgM,eosinophil cationic protein(ECP),and interleukin(IL)-4,as well as blood pressure,after injecting QI and its components on the forelimb veins of Beagles were observed.RESULTS:According to comprehensive determination of abnormal behavior scores and changes in serum levels of histamine,IgE,IgG,IgM,ECP,and IL-4,as well as in blood pressure,radix isatidis and hyodeoxycholic acid caused anaphylactoid reactions,and honeysuckle,radix isatidis,hydrolysate,cholic acid and Gardenia jasminoides caused allergic reactions.The anaphylaxis of QI involved anaphylactoid and allergic reactions.CONCLUSION:QI and its components need to be refined further to improve the safety,efficacy,and quality of its use in clinical settings.
基金supported by the National Key Basic Research Project (2013CB530601 to X. Li)the National Natural Science Foundation of China (81270954, 31571401 to X. Li)
文摘Activating transcription factor 5(ATF5) is a member of the activating transcription factor/cA MP response element binding protein(ATF/CREB) family, and is highly expressed in liver and adipose tissue. Previous reports have shown that ATF5 promoted 3T3-L1 preadipocytes differentiation. In this study, we found that ATF5 was highly expressed in mature adipocytes, suggesting a potential role of ATF5 in mature adipocytes, which has not been reported previously. To understand the function of ATF5 in mature adipocytes, we knocked down the expression of ATF5 in 3T3-L1 mature adipocytes and observed decreased lipid droplets. Consistent with the in vitro experiment, the knockdown of ATF5 in white adipose tissue led to less adipose tissue and smaller adipocytes size. Further research revealed that the inhibition of ATF5 diminished the adipocytes size via the inhibition of fatty acid synthetase, stearyl coenzyme A desaturation enzyme 1, and the induction of carnitine palmitoyl transferase 1, one key enzyme of lipid metabolism. In addition, ATF5 knockdown in inguinal white adipose tissue improved whole body insulin sensitivity.Our work provides a new understanding of ATF5 function in mature adipocytes and a potential therapeutic target of diabetes.
