PtSnNa/SUZ-4:An efficient catalyst for propane dehydrogenation

The structure and catalytic properties of PtSn catalysts supported on SUZ-4 and ZSM-5 zeolite have been studied by using various experimental techniques including XRD,nitrogen adsorption,NH3-TPD,TG,H2-TPR and TPO techniques combined with propane dehydrogenation tests.It has been shown that SUZ-4-supported PtSnNa（PtSnNa/SUZ-4） was determined to be a better catalyst for propane dehydrogenation than conventional catalysts supported on ZSM-5,owing to its higher catalytic activity and stability.Dibenzothiophene poisoning experiments were performed to investigate the detailed structures of the two supported catalysts.The characterization of the two catalysts indicates that the distribution of Pt on the porous support affects the activity.In contrast to ZSM-5-supported catalysts,Pt particles on the PtSnNa/SUZ-4 are primarily dispersed over the external surface and are not as readily deactivated by carbon deposition.This is because that the strong acid sites of the SUZ-4 zeolite evidently prevented the impregnation of the Pt precursor H_2PtCl_6 into the zeolite.In contrast,the weak acid sites of the ZSM-5 zeolite led to more of the precursor entering the zeolite tunnels,followed by transformation to highly dispersed Pt clusters during calcination.In the case of the PtSnNa/ZSM-5,the interactions between Sn oxides and the support were lessened,owing to the weaker acidity of the ZSM-5 zeolite.The dispersed Sn oxides were therefore easier to reduce to the metallic state,thus decreasing the catalytic activity for hydrocarbon dehydrogenation.

Fabrication of amino-functionalized Fe_3O_4@Cu_3(BTC)_2 for heterogeneous Knoevenagel condensation

Metal organic frameworks（MOFs） are an important platform for heterogeneous catalysts.Although MOFs with a smaller particle size exhibit better catalytic performance because of less diffusion limitations,their separation and recycling after catalytic reactions are difficult.The integration of MOFs with magnetic nanoparticles could facilitate their recovery and separation.Especially,the shell thickness of the core-shell structured composites is controllable.In this study,amino-functionalized Fe3O4@Cu3（BTC）2 was fabricated by a stepwise assembly method and its catalytic performance in Knoevenagel condensation was investigated.The results demonstrated that the magnetic hybrid material exhibited a core-shell structure,with a shell thickness of about 2 00 nm.Furthermore,it not only exhibited high catalytic activity,but remarkably,it could also be easily recovered magnetically and recycled without obvious loss of catalytic efficiency after three cycles.

Differentiation of Sheeppox and Goatpox Viruses by Polymerase Chain Reaction-Restriction Fragment Length Polymorphism

In the present study,the partial gene sequences of P32 protein,an immunogenic envelope protein of Capripoxviruses (CaPV),were analyzed to assess the genetic relationship among sheeppox and goatpox virus isolates,and restriction enzyme specific PCR-RFLP was developed to differentiate CaPV strains.A total of six goatpox virus (GTPV) and nine sheeppox virus (SPPV) isolates of Indian origin were included in the sequence analysis of the attachment gene.The sequence analysis revealed a high degree of sequence identity among all the Indian SPPV and GTPV isolates at both nucleotide and amino acid levels.Phylogenetic analysis showed three distinct clusters of SPPV,GTPV and Lumpy skin disease virus (LSDV) isolates.Further,multiple sequence alignment revealed a unique change at G120A in all GTPV isolates resulting in the formation of Dra I restriction site in lieu of EcoR I,which is present in SPPV isolates studied.This change was unique and exploited to develop restriction enzyme specific PCR-RFLP for detection and differentiation of SPPV and GTPV strains.The optimized PCR-RFLP was validated using a total of fourteen (n=14) cell culture isolates and twenty two (n=22) known clinical samples of CaPV.The Restriction Enzyme specific PCR-RFLP to differentiate both species will allow a rapid differential diagnosis during CaPV outbreaks particularly in mixed flocks of sheep and goats and could be an adjunct/supportive tool for complete gene or virus genome sequencing methods.

Dynamic modelling and PFL-based trajectory tracking control for underactuated cable-driven truss-like manipulator

In recent years,an innovative underactuated robot was developed,named as underactuated cable-driven trusslike manipulator(UCTM),to be suitable in aerospace applications.However,there has been strong consensus that the stabilization of planar underactuated manipulators without gravity is a great challenge since the system includes a second order nonholonomic constraint and most classical control methods are not suitable for this kind of system.Furthermore,the complexity of the truss-like structure results in tremendous difficulty of computational complicacy and high nonlinearity during dynamic modelling in addition to controller design.It is paramount to solve these difficulties for UCTM's future applications.To solve the above difficulties,this paper presents a dynamic modelling method for UCTM and a trajectory tracking control method based on partial feedback linearization(PFL)that fulfills the control goal of moving UCTM from its original position to a desired position by tracking a given trajectory of the joint angles.To achieve this,a model equivalent method is proposed to make UCTM equivalent with a three-link manipulator in the sense of dynamic behavior.Then the Lagrangian equation combined with complex vector method is proposed in the dynamic modelling process of UCTM,which simplifies the derivation procedure.Based on the established dynamic model,a coordinate transformation method is proposed to transform the control force matrix into the conventional form of an underactuated system,so that the control force can be separated from the unactuated term.The PFL method in combination with the LQR control method is then proposed to realize the targets that the joint angles can track given desired trajectory.Simulation experiments are conducted to verify the correctness and effectiveness of the proposed methods.

Fe_3O_4@UiO-66-NH_2 core–shell nanohybrid as stable heterogeneous catalyst for Knoevenagel condensation

separation is an attractive alternative to filtration or centrifugation for separating solid catalysts from a liquid phase, Here, core-shell Fe3O4@UiO-66-NH2 nanohybrids with well-defined structures were constructed by dispersing magnets in a dimethylformamide （DMF） solution con- taining two metal-organic framework （MOF） precursors, namely ZrCI4 and 2-aminobenzenetricar- boxylic acid. This method is simpler and more efficient than previously reported step-by-step method in which magnets were consecutively dispersed in DMF solutions each containing one MOF precursor, and the obtained Fe304@UiO-66-NH2 with three assembly cycles has a higher degree of crystallinity and porosiW. The core-shell Fe3O4@UiO-66-NH2 is highly active and selective in Knoevenagel condensations because of the bifunctionality of UiO-66-NH2 and better mass transfer in the nano-sized shells. It also has good recycling stability, and can be recovered magnetically and reused at least four times without significant loss of catalytic activity and framework integrity. The effects of substitution on the reactivity of benzaldehyde and of substrate size were also investigated.

Efficient synthesis of pyrano[2,3-d]pyrimidinone and pyrido[2,3-d]pyrimidine derivatives in presence of novel basic ionic liquid catalyst

A basic ionic liquid, namely 1,1＇-（butane-1,4-diyl）bis（1,4-diazabicyclo [2.2.2]octan-1-ium） hydrox-ide, was prepared and characterized using Fourier-transform infrared spectroscopy, XH nuclear magnetic resonance spectroscopy, and pH measurements. The ionic liquid was used for efficient promotion of the synthesis of pyrano[2,3-d]pyrimidinone and pyrido[2,3-d]pyrimidine derivatives at room temperature under grinding conditions. A simple procedure, short reaction time, high yields, non-column chromatographic separation, commercial availability of the starting materials, and recyclability of the catalyst are attractive features of this process.

Effect of heat treatment on structure and gasification reactivity of petroleum coke

Petroleum coke was thermally treated on a fixed bed reactor in a temperature range of 1173-1673 K. The changes of the elemental composition and crystalline structure of petroleum coke, with heat treatments as well as the gasification reactivity of the heat-treated petroleum cokes were investigated. The results showed that the petroleum coke was carbonized and grapbitized to a higher degree with increasing heating temperature, while the gasification reactivity decreased. The treatment at temperatures of 1173 and 1473 K significantly enlarged the specific surface area and the pore volume of petroleum coke. Both the specific surface area and the pore volume decreased at 1673 K. An empirical normal distribution function model （NDFM） was found to fit the gasification rates of petroleum coke well. The correlation coefficient of petroleum coke by normal distribution function model at different heat treatment temperatures is between 0.93 and 0.95.

Effect of Sulfurization Temperature on Thioetherification Performance of Mo-Ni/Al_2O_3 Catalyst

The Mo modified Ni/Al_2O_3 catalysts were prepared and sulfided at different temperatures, and their catalytic activity for thioetherification of mercaptans and olefins(or dienes), hydrogenation of dienes and olefins in the thioetherification process using fluidized catalytic cracking(FCC) naphtha as the feedstock was investigated. In order to disclose the correlation between the physicochemical characteristics of catalysts and their catalytic activity, the surface structures and properties of the catalysts sulfided at different temperatures were characterized by the high resolution transmission electronic microscopy(HRTEM), X-ray photoelectron spectroscopy(XPS) and H2-temperature programmed reduction(H_2-TPR) technique. The results showed that an increase of sulfurization temperature not only could promote the sulfurization degree of active metals on the catalysts, but also could adjust the micro-morphology of active species. These changes could improve the catalytic performance of thioetherification, and hydrogenation of dienes and olefins. However, an excess sulfurization temperature was more easily to upgrade the ability of the catalyst for hydrogenation of olefins, which could lead to a decrease of the octane number of the product. It was also showed that a moderate sulfurization temperature not only could improve the catalytic performance of thioetherification and hydrogenation of dienes but also could control hydrogenation of olefins.

Steric Effects in the Cl＋CHD3（v1=1） Reaction

A recent study has revealed a full 3-dimentional reactive scattering picture of the reaction CI＋CHD3（v1=1） as the C1 atoms attack CHD3 from various directions respective to the C-H stretching bond. The reported polarization-dependent differential cross sections provide the most detailed characterization of the influences of reagent alignments on reactivity. To convey the stereo-specific information more accessible to general chemists, we show here, by proper symmetry considerations, how to retrieve from the measurements the relative integral and differential cross sections of two most common collision geometries： the end-on versus side-on attacks. The results, albeit coarse-grained, provide an appealing picture that not only reinforces our intuition about chemical reactivity, but also sheds more light on the conventional （unpolarized） attributes.

Compatible stability study of Xing NaoJing injection based on physical-chemical properties analysis

Objective:The clinical treatment of brain diseases is urgent. Xingnaojing (XNJ) injection is often used in combination with other injection drugs. Due to the possible interaction between the injections in vivo, the particle size, osmotic pressure, pH value change and component stability decrease, that is one of the important factors causing various adverse reactions. Based on the above situation, this study investigated the physical properties and chemical composition changes of XNJ injection and its compatibility solvent and 13 kinds of clinical injection, speculated the possible interactions between the drugs in vivo from the perspective of in vitro compatibility stability, find out the safety risks of adverse reactions and provide guidance for the safe and rational use of XNJ injection. Methods:According to the clinical application, XNJ injection was mixed with 13 combination injections based on 250 mL 5% glucose injection, and placed at room temperature for 6 h. Then, the clarity, particle size, pH, osmolality, and the contents of camphor, d-borneol, and muscone of the compatible solutions were detected at 0, 1, 2, 4, and 6 h, respectively. Results:The results showed that the physical-chemical properties of compatibility solution were slightly influenced when XNJ was combined with Alprostadil injection and Danhong injection. The change of particle size and the degradation of muscone content were the main factors affecting the compatibility stability of XNJ injection, indicating that there are some problems in compatibility stability, which may be one of the causes of clinical adverse reactions. Conclusion:This study suggests that XNJ injection in combination with other injections during intravenous administration should be performed cautiously.

An efficient synthesis of polysubstituted tetrahydropyrimidines using acidic Al_2O_3 as solid media

A series of polysubstituted tetrahydropyrimidines were synthesized in moderate to good yields via a one-pot, four-component reaction of an alkyne, formaldehyde, and amines in solid media acidic Al2O3. The advantages of this protocol include mild reaction conditions, broad substrate scope, and environmentally friendly reaction media.

Determining method,conditional factors,traits and applications of nonlinear chemical fingerprint by using dissipative components in samples

The thermodynamic systems and dynamic model suitable for determining the nonlinear chemical fingerprints of samples were analyzed.The results indicated that the damp nonlinear chemical reactions in close systems away from the equilibrium and open systems without the complementarity of the dissipation substances have important significance for the throng characterization and whole content analysis of chemical components in samples.Various factors influencing on nonlinear chemical fingerprint,such as reactant species and their concentrations,electrode types,temperature,stir rate,the sort,dosage and granularity of the sample,etc.were amply researched by a nonlinear chemistry reaction,namely,damp B-Z oscillation which used acetone and glucose as the main dissipative substances.In addition,the quantitative information on the whole of chemical components in samples and the traits and applications of the fingerprint were investigated.The method and its important conditions for determining nonlinear chemistry fingerprint used in distinguishing and evaluating complex samples were successfully put forward.

Nitrogen-rich porphyrinic metal-organic frameworks synthesized by postsynthetic metathesis: from inert material to active catalyst

With the aid of a postsynthetic metathesis method, an inert nitrogen-rich porphyrinic metal-organic framework can exhibit a high catalytic activity in one-pot deacetalization-Knoevenagel condensation reaction.

Ag_(2)O/squaramide cocatalyzed asymmetric interrupted Barton-Zard reaction of 8-nitroimidazo[1,2-a]pyridines

Imidazo[1,2-a]pyridines are present in numerous biologically active compounds as the core structural motif.Herein,we report an asymmetric interrupted Barton-Zard reaction of electron-deficient imidazo[1,2-a]pyridines withα-substituted isocyanoacetates.The reaction enables the dearomatization of 8-nitroimidazo[1,2-a]pyridines and hence offers straightforward access to an array of optically active highly functionalized imidazo[1,2-a]pyridine derivatives that possess three contiguous stereogenic centers in good yields(up to 98%)with high stereoselectivities(>19:1 dr,>99%ee).It is worth noting that the catalytic system consisting of a chiral squaramide and silver oxide displays remarkable reactivity and stereoselectivity,and a gram-scale reaction is compatible with the catalyst loading of 0.5 mol%.In addition,the synthetic potential of this method was showcased by versatile transformations of the product.

A study of nonlinear biochemical reaction model

The present study deals with the introduction of an alteration in Legendre wavelets method by availing of the Picard iteration method for system of differential equations and named it Legendre wavelet-Picard method （LWPM）. Convergence of the proposed method is also discussed. In order to check the competence of the proposed method, basic enzyme kinetics is considered. Systems of nonlinear ordinary differential equations are formed from the considered enzyme-substrate reaction. The results obtained by the proposed LWPM are compared with the numerical results obtained from Runge-Kutta method of order four （RK-4）. Numerical results and those obtained by LWPM are in excellent conformance, which would be explained by the help of table and figures. The proposed method is easy and simple to implement as compared to the other existing analytical methods used for solving systems of differential equations arising in biology, physics and engineering.