目的对主题为肌紧张性发声障碍(muscle tension dysphonia,MTD)的外文文献进行文献计量学分析,了解世界范围内该疾病的研究状况。方法在Web of Science核心合集中检索,检索策略为“muscle tension dysphonia”OR(“MTD”AND“voice”),...目的对主题为肌紧张性发声障碍(muscle tension dysphonia,MTD)的外文文献进行文献计量学分析,了解世界范围内该疾病的研究状况。方法在Web of Science核心合集中检索,检索策略为“muscle tension dysphonia”OR(“MTD”AND“voice”),时间跨度1900~2019年,检索目标区域为Topic。将所有内容以纯文本形式导出,形成本地数据集。使用HistCite进行引文分析,补充不符合检索策略但被本地数据集引用次数较高的文献。使用Excel、HistCite、VOSviewer等工具进行数据分析提取,并对部分数据进行可视化分析。结果检索到符合条件的文献共241篇,总被引次数3621次,每项平均被引次数15.02次,h-index为31。补充密切相关文献18篇。其中,以英文发表的文献最多,共233篇,占比高达96.7%,其它语言不足5%。美国是发表此类研究文献最多的国家,拥有较多研究机构和作者。发表此类研究最多的期刊是《Journal of Voice》,共发表相关文献100篇。通过关键词分析对MTD的研究热点进行了展望。结论MTD是一种多因素导致的嗓音异常及咽喉部不适症状,目前研究尚未能完全对其进行解析,对该病的治疗方案仍在不断探索中。目前MTD诊治中仍存在较多问题,需要研究者进行更加深入的探讨。展开更多
Background Recurrence of takotsubo cardiomyopathy （TTC） is a well-known complication. However, current literature lists only a few isolated cases. We aimed to determine the incidence and clinical significance of rec...Background Recurrence of takotsubo cardiomyopathy （TTC） is a well-known complication. However, current literature lists only a few isolated cases. We aimed to determine the incidence and clinical significance of recurrent TTC. Methods ＆ Results Our institutional database constituted a collective of 114 patients diagnosed with TTC since 2003. Close follow-up of these patients revealed a recurrence of TTC in seven of these （6.1%）. The time interval between the index event and its recurrence varied between six months and six years. Arterial hypertension was more revealed in the recurrence group of TTC compared to non-recurrence group, （P = 0.02）. Chronic obstructive pulmo- nary disease and/or asthma was more diagnosed in the recurrence group, （P = 0.04）. Clinical events like fight ventficular involvement, TTC related complications such as life-threatening arrhythmias, pulmonary congestion and in hospital death were observed more frequently in the recurrent episode. Over a mean follow-up of one year the mortality rate was similar in both groups. Conclusions Recurrence of TTC within six years after index event is not an uncommon phenomenon. In the event of right ventricular involvement in the relapse phase, it might be associated with a higher complication rate. TTC recurrence should be the first differential diagnosis in patients with a past history of TTC.展开更多
The aim of the study was to investigate effect of transport times of up to 12 h on pigs＇ welfare. An observation box was located on the 3rd floor of the vehicle. Device to measure temperature, humidity and video came...The aim of the study was to investigate effect of transport times of up to 12 h on pigs＇ welfare. An observation box was located on the 3rd floor of the vehicle. Device to measure temperature, humidity and video camera to monitor pigs＇ behaviors were fitted in the box. Eighteen measurements were performed during two seasons for 4, 8, and 12 h of transport time with three replications. Meat samples were taken from longissimus dorsi （LD） and the carcases were chilled for 24 h at ＋4 ~C for pH determination. To determine cortisol, glucose, lactate, and creatine kinase concentration levels, blood samples were collected before and after transport from 90 pigs and from 20 controls that were not transported for control purposes. To evaluate behavioural alterations, frequency of events and durations were considered. Highest pH24 of 5.99 ＋ 0.29 occurred during summer at 12 h transport time. Cortisol concentrations elevated during short and decreased with an increase of transport time （P 〈 0.001）. Highest and lowest glucose concentrations for winter and summer were at 8 and 12 h transport time, respectively （P 〈 0.01）. Concentrations of lactate and creatine kinase positively correlated with transport time （P 〈 0.002）. Lying, sitting, rooting and vocalization behaviours correlated with transport time （P 〈 0.009）. Certain THI values during summer surpassed normal （〉 74） level during loading. The pH24 value correlated with transport time during summer. Lactate and creatine kinase concentrations increased with an increase in transport time but for Glucose, highest value was at 8 h transport time.展开更多
文摘目的对主题为肌紧张性发声障碍(muscle tension dysphonia,MTD)的外文文献进行文献计量学分析,了解世界范围内该疾病的研究状况。方法在Web of Science核心合集中检索,检索策略为“muscle tension dysphonia”OR(“MTD”AND“voice”),时间跨度1900~2019年,检索目标区域为Topic。将所有内容以纯文本形式导出,形成本地数据集。使用HistCite进行引文分析,补充不符合检索策略但被本地数据集引用次数较高的文献。使用Excel、HistCite、VOSviewer等工具进行数据分析提取,并对部分数据进行可视化分析。结果检索到符合条件的文献共241篇,总被引次数3621次,每项平均被引次数15.02次,h-index为31。补充密切相关文献18篇。其中,以英文发表的文献最多,共233篇,占比高达96.7%,其它语言不足5%。美国是发表此类研究文献最多的国家,拥有较多研究机构和作者。发表此类研究最多的期刊是《Journal of Voice》,共发表相关文献100篇。通过关键词分析对MTD的研究热点进行了展望。结论MTD是一种多因素导致的嗓音异常及咽喉部不适症状,目前研究尚未能完全对其进行解析,对该病的治疗方案仍在不断探索中。目前MTD诊治中仍存在较多问题,需要研究者进行更加深入的探讨。
文摘Background Recurrence of takotsubo cardiomyopathy （TTC） is a well-known complication. However, current literature lists only a few isolated cases. We aimed to determine the incidence and clinical significance of recurrent TTC. Methods ＆ Results Our institutional database constituted a collective of 114 patients diagnosed with TTC since 2003. Close follow-up of these patients revealed a recurrence of TTC in seven of these （6.1%）. The time interval between the index event and its recurrence varied between six months and six years. Arterial hypertension was more revealed in the recurrence group of TTC compared to non-recurrence group, （P = 0.02）. Chronic obstructive pulmo- nary disease and/or asthma was more diagnosed in the recurrence group, （P = 0.04）. Clinical events like fight ventficular involvement, TTC related complications such as life-threatening arrhythmias, pulmonary congestion and in hospital death were observed more frequently in the recurrent episode. Over a mean follow-up of one year the mortality rate was similar in both groups. Conclusions Recurrence of TTC within six years after index event is not an uncommon phenomenon. In the event of right ventricular involvement in the relapse phase, it might be associated with a higher complication rate. TTC recurrence should be the first differential diagnosis in patients with a past history of TTC.
文摘The aim of the study was to investigate effect of transport times of up to 12 h on pigs＇ welfare. An observation box was located on the 3rd floor of the vehicle. Device to measure temperature, humidity and video camera to monitor pigs＇ behaviors were fitted in the box. Eighteen measurements were performed during two seasons for 4, 8, and 12 h of transport time with three replications. Meat samples were taken from longissimus dorsi （LD） and the carcases were chilled for 24 h at ＋4 ~C for pH determination. To determine cortisol, glucose, lactate, and creatine kinase concentration levels, blood samples were collected before and after transport from 90 pigs and from 20 controls that were not transported for control purposes. To evaluate behavioural alterations, frequency of events and durations were considered. Highest pH24 of 5.99 ＋ 0.29 occurred during summer at 12 h transport time. Cortisol concentrations elevated during short and decreased with an increase of transport time （P 〈 0.001）. Highest and lowest glucose concentrations for winter and summer were at 8 and 12 h transport time, respectively （P 〈 0.01）. Concentrations of lactate and creatine kinase positively correlated with transport time （P 〈 0.002）. Lying, sitting, rooting and vocalization behaviours correlated with transport time （P 〈 0.009）. Certain THI values during summer surpassed normal （〉 74） level during loading. The pH24 value correlated with transport time during summer. Lactate and creatine kinase concentrations increased with an increase in transport time but for Glucose, highest value was at 8 h transport time.
