The increasing impact of disasters at local,national,regional and global scales in recent decades has provided enough evidence to urgently direct attention towards the necessity of disaster risk reduction and manageme...The increasing impact of disasters at local,national,regional and global scales in recent decades has provided enough evidence to urgently direct attention towards the necessity of disaster risk reduction and management,and this requires knowledge.Knowledge without communication is barren,and to communicate the risk of disaster it is necessary to understand the perception of the people at risk.In particular,this paper deals with the necessity to delineate strategies of risk communication in pursuance of risk knowledge as a core of disaster risk reduction and management,especially in mountain areas of developing countries.To portray this issue,an analysis of landslide risk perception in terms of experience,landslide risk awareness,exposure,preparedness,and risk communication and trust was undertaken in the municipality of Teziutlán,Puebla,Mexico,an area that has been affected for several decades by episodes of mass movement.Analysis of the responses to a risk perception questionnaire has offered valuable insights in terms of the information and knowledge most required by the people living in the area of interest,in order to devise a realistic and functional strategy to communicate the risk of a landslide disaster.This includes better understanding of controlling factorsand drivers of this risk,and the establishment of potential trusted sources of risk communication.Beyond considering practical matters of risk assessment and management,risk perception and communication can increase the resilience of vulnerable people,and can enhance capacity building for present and future generations.展开更多
Although plasma cell infiltration is not rare in autopsy of patients with multiple myeloma （MM）, it is very rarely detected in living patients. This is because MM rarely causes significant liver dysfunction that req...Although plasma cell infiltration is not rare in autopsy of patients with multiple myeloma （MM）, it is very rarely detected in living patients. This is because MM rarely causes significant liver dysfunction that requires further evaluation. A 49-year-old man presented with acute renal failure and was diagnosed with kappa light chain MM stageⅡB. Thalidomide and dexamethasone were initiated. The patient developed a continuous increase in bilirubin that led to severe cholestasis. A liver biopsy revealed plasma cell infiltration. He then rapidly progressed to liver failure and died. Treatment options are limited in MM with significant liver dysfunction. Despite new drug therapies in MM, those patients with rapidly progressive liver failure appear to have a dismal outcome.展开更多
基金the financial support provided by CONACyT through the research project 156242
文摘The increasing impact of disasters at local,national,regional and global scales in recent decades has provided enough evidence to urgently direct attention towards the necessity of disaster risk reduction and management,and this requires knowledge.Knowledge without communication is barren,and to communicate the risk of disaster it is necessary to understand the perception of the people at risk.In particular,this paper deals with the necessity to delineate strategies of risk communication in pursuance of risk knowledge as a core of disaster risk reduction and management,especially in mountain areas of developing countries.To portray this issue,an analysis of landslide risk perception in terms of experience,landslide risk awareness,exposure,preparedness,and risk communication and trust was undertaken in the municipality of Teziutlán,Puebla,Mexico,an area that has been affected for several decades by episodes of mass movement.Analysis of the responses to a risk perception questionnaire has offered valuable insights in terms of the information and knowledge most required by the people living in the area of interest,in order to devise a realistic and functional strategy to communicate the risk of a landslide disaster.This includes better understanding of controlling factorsand drivers of this risk,and the establishment of potential trusted sources of risk communication.Beyond considering practical matters of risk assessment and management,risk perception and communication can increase the resilience of vulnerable people,and can enhance capacity building for present and future generations.
文摘Although plasma cell infiltration is not rare in autopsy of patients with multiple myeloma （MM）, it is very rarely detected in living patients. This is because MM rarely causes significant liver dysfunction that requires further evaluation. A 49-year-old man presented with acute renal failure and was diagnosed with kappa light chain MM stageⅡB. Thalidomide and dexamethasone were initiated. The patient developed a continuous increase in bilirubin that led to severe cholestasis. A liver biopsy revealed plasma cell infiltration. He then rapidly progressed to liver failure and died. Treatment options are limited in MM with significant liver dysfunction. Despite new drug therapies in MM, those patients with rapidly progressive liver failure appear to have a dismal outcome.
