Recent trend on ongoing changes has unfolded the truth that people are the actors of environmental and social changes. The decade following the restoration of multi-party democracy witnessed a number of economic refor...Recent trend on ongoing changes has unfolded the truth that people are the actors of environmental and social changes. The decade following the restoration of multi-party democracy witnessed a number of economic reforms and development initiatives. The adoption of a liberal, market-oriented development strategy led by private sector has helped to stimulate investment and growth. Nonetheless, development efforts have been largely unsuccessful in integrating the vulnerable and marginalized groups. The governance system has remained non-functional because deeply rooted processes of exclusion have compounded failures at the institutional level and in implementation process. The impacts of development may be measured by several means. This research is an earnest effort to bring new innovations in impact measurement of social inclusion programs. The rigorous processes of finding changes over a period of time and assessing the changes in a ＂wheel＂ are interesting parts of the people lead development in the twenty-first century. Indicators of the development wheel are designed by development professionals of Nepal and rating is done by local stakeholders of Lumbini themselves. The study is based on exploratory and descriptive research design. It follows sequences of appreciative inquiry and development wheel preparation to compare the changes that are in vogue in Nepal. The changes are quantified in three continua that depict the community development programs implemented from 2003 through 2006. This measurement invites rigorous planning and inputs （man, money and time） but it is quite easy for local stakeholders that where they are （in development） and in which direction the currently available and future resources should be streamlined.展开更多
Cancer is a major threat to public health in the 21st century because it is one of the leading causes of death worldwide.The mechanisms of carcinogenesis,cancer invasion,and metastasis remain unclear.Thus,the developm...Cancer is a major threat to public health in the 21st century because it is one of the leading causes of death worldwide.The mechanisms of carcinogenesis,cancer invasion,and metastasis remain unclear.Thus,the development of a novel approach for cancer detection is urgent,and real-time monitoring is crucial in revealing its underlying biological mechanisms.With the optical and chemical advantages of quantum dots(QDs),QD-based nanotechnology is helpful in constructing a biomedical imaging platform for cancer behavior study.This review mainly focuses on the application of QD-based nanotechnology in cancer cell imaging and tumor microenvironment studies both in vivo and in vitro,as well as the remaining issues and future perspectives.展开更多
Studying the carrying capacity of resources and environment of city clusters in the central China has important practical guidance significance for promoting the healthy, sustainable and stable development of this reg...Studying the carrying capacity of resources and environment of city clusters in the central China has important practical guidance significance for promoting the healthy, sustainable and stable development of this region. According to their influencing factors and reciprocity mechanism, using system dynamics approaches, this paper built a SD model for measuring the carrying capacity of resources and environment of the city clusters in the central China, and through setting different development models, the comprehensive measurement analysis on the carrying capacity was carried out. The results show that the model of promoting socio-economic development under the protection of resources and environment is the optimal model for promoting the harmony development of resources, environment, society and economy in the city clusters. According to this model, the optimum population scale of the city clusters in 2020 is 42.80×106 persons, and the moderate economic development scale is 22.055×1012 yuan (RMB). In 1996-2020, the carrying capacity of resources and environment in the city clusters took on obvious phase-change characteristics. During the studied period, it is basically at the initial development stage, and will come through the development process from slow development to speedup development.展开更多
Influencing factors, and variations and trends of Antarctic ozone hole in recent decades are analyzed, and sudden change processes of ozone at Zhongshan station and the effect of atmospheric dynamic processes on ozone...Influencing factors, and variations and trends of Antarctic ozone hole in recent decades are analyzed, and sudden change processes of ozone at Zhongshan station and the effect of atmospheric dynamic processes on ozone changes are also discussed by using the satellite ozone data and the ground-measured ozone data at two Antarctic stations as well as the NCEP/NCAR reanalysis data. The results show that equivalent effective stratospheric chlorine (EESC) and stratospheric temperature are two important factors influencing the ozone hole. The column ozone at Zhongshan and Syowa stations is significantly related with EESC and stratospheric temperature, which means that even though the two stations are both located on the edge of the ozone hole, EESC and stratospheric temperature still played a very important role in column ozone changes, and mean while verifies that EESC is applicable on the coast of east Antarctic continent. Decadal changes in EESC are similar with those of the ozone hole, and inter-annual variations of ozone are closely related with stratospheric temperature. Based on the relation of EESC and ozone hole size, it can be projected that the ozone hole size will gradually reduce to the 1980's level from 2010 to around 2070. Of course there might exist many uncertainties in the projection, which therefore needs to be further studied.展开更多
The advantage of lidar over other wind sensors is presented in this paper. With more than 20 years research, the development of the space-borne wind lidar is reviewed. Longer-term investigation has made many technolog...The advantage of lidar over other wind sensors is presented in this paper. With more than 20 years research, the development of the space-borne wind lidar is reviewed. Longer-term investigation has made many technologies suitable for the wind lidar measurement from an orbital platform become mature. However, there are still some problems to be solved. In order to obtain the optimal performance in wind detection, great importance is being attached to the simulation of a virtual space-borne wind lidar system on computer as developed by NASA and ESA.展开更多
文摘Recent trend on ongoing changes has unfolded the truth that people are the actors of environmental and social changes. The decade following the restoration of multi-party democracy witnessed a number of economic reforms and development initiatives. The adoption of a liberal, market-oriented development strategy led by private sector has helped to stimulate investment and growth. Nonetheless, development efforts have been largely unsuccessful in integrating the vulnerable and marginalized groups. The governance system has remained non-functional because deeply rooted processes of exclusion have compounded failures at the institutional level and in implementation process. The impacts of development may be measured by several means. This research is an earnest effort to bring new innovations in impact measurement of social inclusion programs. The rigorous processes of finding changes over a period of time and assessing the changes in a ＂wheel＂ are interesting parts of the people lead development in the twenty-first century. Indicators of the development wheel are designed by development professionals of Nepal and rating is done by local stakeholders of Lumbini themselves. The study is based on exploratory and descriptive research design. It follows sequences of appreciative inquiry and development wheel preparation to compare the changes that are in vogue in Nepal. The changes are quantified in three continua that depict the community development programs implemented from 2003 through 2006. This measurement invites rigorous planning and inputs （man, money and time） but it is quite easy for local stakeholders that where they are （in development） and in which direction the currently available and future resources should be streamlined.
基金supported by the Academic Award for Excellent Ph.D.Candidates Funded by the Ministry of Education of China(No.5052011303014)the National Natural Science Foundation of China(No.81171396)+1 种基金the Science Fund for Creative Research Groups of the National Natural Science Foundation of China(Nos.20621502 and 20921062)the Fundamental Research Funds for the Central Universities of Ministry of Education of China(No.4103005).
文摘Cancer is a major threat to public health in the 21st century because it is one of the leading causes of death worldwide.The mechanisms of carcinogenesis,cancer invasion,and metastasis remain unclear.Thus,the development of a novel approach for cancer detection is urgent,and real-time monitoring is crucial in revealing its underlying biological mechanisms.With the optical and chemical advantages of quantum dots(QDs),QD-based nanotechnology is helpful in constructing a biomedical imaging platform for cancer behavior study.This review mainly focuses on the application of QD-based nanotechnology in cancer cell imaging and tumor microenvironment studies both in vivo and in vitro,as well as the remaining issues and future perspectives.
基金Under the auspices of National Natural Science Foundation of China (No. 40971101)Major Project of 11th Five-Year Scientific and Technological Support Plan of China (No. 2006BAJ14B03)
文摘Studying the carrying capacity of resources and environment of city clusters in the central China has important practical guidance significance for promoting the healthy, sustainable and stable development of this region. According to their influencing factors and reciprocity mechanism, using system dynamics approaches, this paper built a SD model for measuring the carrying capacity of resources and environment of the city clusters in the central China, and through setting different development models, the comprehensive measurement analysis on the carrying capacity was carried out. The results show that the model of promoting socio-economic development under the protection of resources and environment is the optimal model for promoting the harmony development of resources, environment, society and economy in the city clusters. According to this model, the optimum population scale of the city clusters in 2020 is 42.80×106 persons, and the moderate economic development scale is 22.055×1012 yuan (RMB). In 1996-2020, the carrying capacity of resources and environment in the city clusters took on obvious phase-change characteristics. During the studied period, it is basically at the initial development stage, and will come through the development process from slow development to speedup development.
基金supported by the program of China Polar Environment Investigation and Assessment(2011-2015)the National Nature Science Foundation of China (No. 41076132)
文摘Influencing factors, and variations and trends of Antarctic ozone hole in recent decades are analyzed, and sudden change processes of ozone at Zhongshan station and the effect of atmospheric dynamic processes on ozone changes are also discussed by using the satellite ozone data and the ground-measured ozone data at two Antarctic stations as well as the NCEP/NCAR reanalysis data. The results show that equivalent effective stratospheric chlorine (EESC) and stratospheric temperature are two important factors influencing the ozone hole. The column ozone at Zhongshan and Syowa stations is significantly related with EESC and stratospheric temperature, which means that even though the two stations are both located on the edge of the ozone hole, EESC and stratospheric temperature still played a very important role in column ozone changes, and mean while verifies that EESC is applicable on the coast of east Antarctic continent. Decadal changes in EESC are similar with those of the ozone hole, and inter-annual variations of ozone are closely related with stratospheric temperature. Based on the relation of EESC and ozone hole size, it can be projected that the ozone hole size will gradually reduce to the 1980's level from 2010 to around 2070. Of course there might exist many uncertainties in the projection, which therefore needs to be further studied.
基金supported by National High Tech 863 Project(No.2002AA135280)National Natural Science Foundation of China No.40176011International Bureau of BMBF
文摘The advantage of lidar over other wind sensors is presented in this paper. With more than 20 years research, the development of the space-borne wind lidar is reviewed. Longer-term investigation has made many technologies suitable for the wind lidar measurement from an orbital platform become mature. However, there are still some problems to be solved. In order to obtain the optimal performance in wind detection, great importance is being attached to the simulation of a virtual space-borne wind lidar system on computer as developed by NASA and ESA.
