In this essay the author makes a review of the book Discoveries and Studies of Islamic-world Cultural Relics in China,which introduces comprehensively the substantial Islamic cultural relics from abroad unearthed in C...In this essay the author makes a review of the book Discoveries and Studies of Islamic-world Cultural Relics in China,which introduces comprehensively the substantial Islamic cultural relics from abroad unearthed in China in the past over half a century,and,by analyzing relevant literal records and making comparative studies between these objects and their counterparts in Chinese cultural heritage,demonstrates one side of Sino-Islamic cultural exchange in AD 8th to 15th centuries.Thus the book made up the gap in this academic field.展开更多
This review starts with a brief history of drug discovery & development, and the place of Asia in this worldwide effort discussed. The conditions and constraints of a successful translational R&D involving aca...This review starts with a brief history of drug discovery & development, and the place of Asia in this worldwide effort discussed. The conditions and constraints of a successful translational R&D involving academic basic research and clinical research are discussed and the Singapore model for pursuit of open R&D described. The importance of well-characterized, validated drug targets for the search for novel targeted anti-cancer agents is emphasized, as well as a structured, high quality translational R&D. Furthermore, the characteristics of an attractive preclinical development drug candidate are discussed laying the foundation of a successful preclinical development. The most frequent sources of failures are described and risk management at every stage is highly recommended. Organizational factors are also considered to play an important role. The factors to consider before starting a new drug discovery & development project are described, and an example is given of a successful clinical project that has had its roots in local universities and was carried through preclinical development into phase I clinical trials.展开更多
文摘In this essay the author makes a review of the book Discoveries and Studies of Islamic-world Cultural Relics in China,which introduces comprehensively the substantial Islamic cultural relics from abroad unearthed in China in the past over half a century,and,by analyzing relevant literal records and making comparative studies between these objects and their counterparts in Chinese cultural heritage,demonstrates one side of Sino-Islamic cultural exchange in AD 8th to 15th centuries.Thus the book made up the gap in this academic field.
文摘This review starts with a brief history of drug discovery & development, and the place of Asia in this worldwide effort discussed. The conditions and constraints of a successful translational R&D involving academic basic research and clinical research are discussed and the Singapore model for pursuit of open R&D described. The importance of well-characterized, validated drug targets for the search for novel targeted anti-cancer agents is emphasized, as well as a structured, high quality translational R&D. Furthermore, the characteristics of an attractive preclinical development drug candidate are discussed laying the foundation of a successful preclinical development. The most frequent sources of failures are described and risk management at every stage is highly recommended. Organizational factors are also considered to play an important role. The factors to consider before starting a new drug discovery & development project are described, and an example is given of a successful clinical project that has had its roots in local universities and was carried through preclinical development into phase I clinical trials.
