Objective: The aim of the study was to discuss the diagnostic value of dynamic contrast enhanced-magnetic resonance imaging (DCE-MRI) in distinguishing malignant tumors of breast from benign lesions. Methods: A DCE-MR...Objective: The aim of the study was to discuss the diagnostic value of dynamic contrast enhanced-magnetic resonance imaging (DCE-MRI) in distinguishing malignant tumors of breast from benign lesions. Methods: A DCE-MRI study was performed on 18 benign lesions, 16 malignant tumors and 2 borderline lesions of breast (mean age 51.7 years). The seven items including shape, marginal feature, spreading signs, time-signal intensity curve, maximum slope of increase (MSI), signal enhancement ratio (SER) and signal enhanced extent (SEE) were compared between patients with benign lesions and those with malignant tumors. Results: Shape, marginal feature, spreading signs, time-signal intensity curve, SEE and SER between the benign and malignant groups of breast represented significantly difference except MSI. The 36 cases with breast lesion displayed sensitivity, specificity, accuracy for diagnosing malignant tumor of breast using the scoring method was 93.8%, 83.3% and 88.2%, respectively. Conclusion: DCE-MRI combined with morphology and dynamic enhanced feature of breast lesion has well efficacy to differentiate malignant tumor from benign lesions.展开更多
基金Supported by a grant from the Sciences Foundation of West district, Beijing, China (No. 06027)
文摘Objective: The aim of the study was to discuss the diagnostic value of dynamic contrast enhanced-magnetic resonance imaging (DCE-MRI) in distinguishing malignant tumors of breast from benign lesions. Methods: A DCE-MRI study was performed on 18 benign lesions, 16 malignant tumors and 2 borderline lesions of breast (mean age 51.7 years). The seven items including shape, marginal feature, spreading signs, time-signal intensity curve, maximum slope of increase (MSI), signal enhancement ratio (SER) and signal enhanced extent (SEE) were compared between patients with benign lesions and those with malignant tumors. Results: Shape, marginal feature, spreading signs, time-signal intensity curve, SEE and SER between the benign and malignant groups of breast represented significantly difference except MSI. The 36 cases with breast lesion displayed sensitivity, specificity, accuracy for diagnosing malignant tumor of breast using the scoring method was 93.8%, 83.3% and 88.2%, respectively. Conclusion: DCE-MRI combined with morphology and dynamic enhanced feature of breast lesion has well efficacy to differentiate malignant tumor from benign lesions.
