腰椎间盘突出症是指椎间盘的纤维环破裂、髓核突出,压迫和刺激神经根所致的一系列症状体征,即根性症状,其中以L4.5椎间盘(D4)及L5S1椎间盘(D5)居多,临床工作中经常发现根性症状与被压迫神经根应出现症状的不一致现象,但这种不一致现象,...腰椎间盘突出症是指椎间盘的纤维环破裂、髓核突出,压迫和刺激神经根所致的一系列症状体征,即根性症状,其中以L4.5椎间盘(D4)及L5S1椎间盘(D5)居多,临床工作中经常发现根性症状与被压迫神经根应出现症状的不一致现象,但这种不一致现象,即根性症状多变性(Variance of radiculopa-thy),随着近年来微创技术的广泛采用[1],要求对这一现象进一步明确,以指导临床手术.展开更多
It is demonstrated by sociolinguistic variation studies that women are more likely than men to use standard speech. This paper reviews the operational methods and analytical means of classic quantitative studies in th...It is demonstrated by sociolinguistic variation studies that women are more likely than men to use standard speech. This paper reviews the operational methods and analytical means of classic quantitative studies in this field, intending to provide guidance and enlightenment for relevant studies and verifications in the context of Chinese culture.展开更多
The effects of different dietary lipid content on the growth and lipase activity ofEriocheir sinensis larvae were studied in the paper. The results showed that the survival, metamorphic rate and weight gain of E. sine...The effects of different dietary lipid content on the growth and lipase activity ofEriocheir sinensis larvae were studied in the paper. The results showed that the survival, metamorphic rate and weight gain of E. sinensis larvae at different stages of growth all varied significantly with lipid content (P〈0.05). Further, the survival and metamorphosis rates were the highest during the larval phases Z3 to Z4, and the weight gain was the highest during the larval phases Z5 to M. During the first 20h after metamorphosis of every larval stage, the lipase activity increased over time at Z1, Z2, Z3 and M and declined at Z4 and Zs, and was influenced significantly by lipid content (P〈0.05). In addition, lipase activity at each larval stage began to respond to dietary lipid contents 4h after the larvae were fed, and tended to be stable after 12 h. The diets with higher lipase activity and lower lipid content were selected to give the suitable recipe of lipid requirements at each larval stage. It was concluded that the suitable lipid requirements at Zb Z2, Z3, Z4, Z5 and M were 6%, 4% 6%, 8%, 8% and 10%, respectively.展开更多
Objective: To investigate the specific blockage effect of individual antisense RNA on mutant p53 gene in vitro. Methods: The single strand antisense transcription system containing mt-p53 exon 8 sequence (pGEM3zf(...Objective: To investigate the specific blockage effect of individual antisense RNA on mutant p53 gene in vitro. Methods: The single strand antisense transcription system containing mt-p53 exon 8 sequence (pGEM3zf(+/-)p53exon8) was constructed. The ligation of antisense RNAwith mt-p53 gene was confirmed by in situ hybridization; MDA-MB-231 human breast cancer cells were transfected with ASp53exon8'RNA cotionic liposome-mediated. Expression of mt-p53 protein was examined by immunocytochemical staining and Western blot. Cell proliferation was evaluated by MTT assay; Cell cycle distribution was determined by flow cytometry (FCM); Apoptosis was observed by TUNEL. Results: In transfected MDA-MB-231 cells, hybridization signals were observed in cytoplasm. ASp53exon8'RNA transfection induced inhibition of cell proliferation, G2/M phase arrest and increasing apoptotic rates. In addition, expression of p53 protein was down-regulated. Conclusion: pGEM3zf(+/-)p53exon8 was well constructed and ASp53exon8'RNA can block mt-p53 gene expression specifically and then inhibit MDA-MB-231 cell proliferation in vitro, which may serve as therapeutic means for human malignancy.展开更多
Objective: To review literature from 1956 to 2007 and explore regularities in points selection and methods for acupuncture-moxibustion treatment of allergic rhinitis. Methods: A comprehensive analysis was made by a ...Objective: To review literature from 1956 to 2007 and explore regularities in points selection and methods for acupuncture-moxibustion treatment of allergic rhinitis. Methods: A comprehensive analysis was made by a method of metrological analysis according to the data from "China Modem Acupuncture-moxibustion Information Databank". Results: Points Yingxiang (LI 20) and Feishu (BL 13) were most frequently used. Acupuncture and hydro-acupuncture were the major treatment methods. Conclusion: It is suggested that Yingxiang (LI 20), Yintang (Ex-HN 3), Feishu (BL 13) and Dazhui (GV 14) be used as a basic prescription for acupuncture-moxibustion treatment of allergic rhinitis, which is combined with point selection based on syndrome differentiation.展开更多
Numerous experimental and theoretical studies on recycled aggregate concrete have been carried out in China in the past 10 years.This paper provides a comprehensive review of the related findings of research on the me...Numerous experimental and theoretical studies on recycled aggregate concrete have been carried out in China in the past 10 years.This paper provides a comprehensive review of the related findings of research on the mechanical properties of RAC in China.The influences of the RCA on the strength and deformation characteristics of concrete,the statistical characteristics for the strength of RAC,fracture energy,stress-strain relationships under uniaxial compression,uniaxial tension as well as pure shear,and the residual strength of RAC after exposure to high temperatures,the bond between RAC and different kinds of steel rebar were also reviewed.Furthermore,some recent studies on the numerical simulation of the failure mechanism for RAC at the meso-structure level were discussed.展开更多
Up to now the chirality is seldom studied in the diluted spin glass although many investigations have been performed on the site-ordered Edwards-Anderson model. By simulation, we investigate the dynamicaJ properties o...Up to now the chirality is seldom studied in the diluted spin glass although many investigations have been performed on the site-ordered Edwards-Anderson model. By simulation, we investigate the dynamicaJ properties of both the spin-glass and the chiral-glass phases in a diluted dipolar system, which was manifested to have a spin-glass transition by recent numerical study. By scaling we find that both phases have the same aging behavior and closer aging parameterμ. Similarly, the domains grow in the same way and both phases have a closer barrier exponent g2. It means that both the spins and the chirality have the same dynamical properties and they may freeze at the same temperature.展开更多
文摘腰椎间盘突出症是指椎间盘的纤维环破裂、髓核突出,压迫和刺激神经根所致的一系列症状体征,即根性症状,其中以L4.5椎间盘(D4)及L5S1椎间盘(D5)居多,临床工作中经常发现根性症状与被压迫神经根应出现症状的不一致现象,但这种不一致现象,即根性症状多变性(Variance of radiculopa-thy),随着近年来微创技术的广泛采用[1],要求对这一现象进一步明确,以指导临床手术.
文摘It is demonstrated by sociolinguistic variation studies that women are more likely than men to use standard speech. This paper reviews the operational methods and analytical means of classic quantitative studies in this field, intending to provide guidance and enlightenment for relevant studies and verifications in the context of Chinese culture.
基金funded by the National Natural Science Foundation of China (No.30100140)the Higher Institutions Doctor research Foundation Projects of China (No.2000042303)the Natural Science Foundation Projects of Province Shandong (No.Y98D15063)
文摘The effects of different dietary lipid content on the growth and lipase activity ofEriocheir sinensis larvae were studied in the paper. The results showed that the survival, metamorphic rate and weight gain of E. sinensis larvae at different stages of growth all varied significantly with lipid content (P〈0.05). Further, the survival and metamorphosis rates were the highest during the larval phases Z3 to Z4, and the weight gain was the highest during the larval phases Z5 to M. During the first 20h after metamorphosis of every larval stage, the lipase activity increased over time at Z1, Z2, Z3 and M and declined at Z4 and Zs, and was influenced significantly by lipid content (P〈0.05). In addition, lipase activity at each larval stage began to respond to dietary lipid contents 4h after the larvae were fed, and tended to be stable after 12 h. The diets with higher lipase activity and lower lipid content were selected to give the suitable recipe of lipid requirements at each larval stage. It was concluded that the suitable lipid requirements at Zb Z2, Z3, Z4, Z5 and M were 6%, 4% 6%, 8%, 8% and 10%, respectively.
基金Key Project Fund of Basic Research, Tianjin Municipal Science and Technology Commission (No. 033801511), and the Scientific Research Foundation for the Returned Overseas Chinese Scholars, State Education Ministry (2004–2005).
文摘Objective: To investigate the specific blockage effect of individual antisense RNA on mutant p53 gene in vitro. Methods: The single strand antisense transcription system containing mt-p53 exon 8 sequence (pGEM3zf(+/-)p53exon8) was constructed. The ligation of antisense RNAwith mt-p53 gene was confirmed by in situ hybridization; MDA-MB-231 human breast cancer cells were transfected with ASp53exon8'RNA cotionic liposome-mediated. Expression of mt-p53 protein was examined by immunocytochemical staining and Western blot. Cell proliferation was evaluated by MTT assay; Cell cycle distribution was determined by flow cytometry (FCM); Apoptosis was observed by TUNEL. Results: In transfected MDA-MB-231 cells, hybridization signals were observed in cytoplasm. ASp53exon8'RNA transfection induced inhibition of cell proliferation, G2/M phase arrest and increasing apoptotic rates. In addition, expression of p53 protein was down-regulated. Conclusion: pGEM3zf(+/-)p53exon8 was well constructed and ASp53exon8'RNA can block mt-p53 gene expression specifically and then inhibit MDA-MB-231 cell proliferation in vitro, which may serve as therapeutic means for human malignancy.
文摘Objective: To review literature from 1956 to 2007 and explore regularities in points selection and methods for acupuncture-moxibustion treatment of allergic rhinitis. Methods: A comprehensive analysis was made by a method of metrological analysis according to the data from "China Modem Acupuncture-moxibustion Information Databank". Results: Points Yingxiang (LI 20) and Feishu (BL 13) were most frequently used. Acupuncture and hydro-acupuncture were the major treatment methods. Conclusion: It is suggested that Yingxiang (LI 20), Yintang (Ex-HN 3), Feishu (BL 13) and Dazhui (GV 14) be used as a basic prescription for acupuncture-moxibustion treatment of allergic rhinitis, which is combined with point selection based on syndrome differentiation.
基金supported by the National Natural Science Foundation of China (Grant No. 51178340)the Shanghai Science and Technology Committee (Grant No. 10231202000)the New Century Excellent Talentsin China Ministry of Education Project (Grant No. NCET-06-0383)
文摘Numerous experimental and theoretical studies on recycled aggregate concrete have been carried out in China in the past 10 years.This paper provides a comprehensive review of the related findings of research on the mechanical properties of RAC in China.The influences of the RCA on the strength and deformation characteristics of concrete,the statistical characteristics for the strength of RAC,fracture energy,stress-strain relationships under uniaxial compression,uniaxial tension as well as pure shear,and the residual strength of RAC after exposure to high temperatures,the bond between RAC and different kinds of steel rebar were also reviewed.Furthermore,some recent studies on the numerical simulation of the failure mechanism for RAC at the meso-structure level were discussed.
基金Supported by National Natural Science Foundation of China under Grant Nos.11247428,61274101Natural Science Foundation of Liaoning Province under Grant No.20121078
文摘Up to now the chirality is seldom studied in the diluted spin glass although many investigations have been performed on the site-ordered Edwards-Anderson model. By simulation, we investigate the dynamicaJ properties of both the spin-glass and the chiral-glass phases in a diluted dipolar system, which was manifested to have a spin-glass transition by recent numerical study. By scaling we find that both phases have the same aging behavior and closer aging parameterμ. Similarly, the domains grow in the same way and both phases have a closer barrier exponent g2. It means that both the spins and the chirality have the same dynamical properties and they may freeze at the same temperature.