“意变”与“写实”:动画和普通影视的美学分野

动画常被归于影视艺术门类,其与普通影视不同的艺术特质未能得到充分揭示。本文以"意变"与"写实"来说明动画与普通影视有着相异的美学方法和美学立场,普通影视刻意写实,动画却强调意变,这既是制造影像的方式的差别,也体现了美学观的分歧,并引导出不同的观众心理。

论《女神》的意象世界

《女神》不仅充满着火山喷发般的激情和粗砺狂暴的格调 ,而且注意意象的营造。郭沫若以泛神论哲学为基础 ,在古今中外诗歌意象理论的影响下 ,他在诗论和创作中十分重视意象理论的阐释和运用。《女神》的意象可归纳为 :神话意象、自然意象、社会意象和文化意象。《女神》的意象创造通常采用变形和变形变意两种方式。

变形:“远取譬”畸联——探究一种张力诗语

变形是现代诗语的特征之一,它表现为"远取譬"的大跨度畸联。变形的图式目的,在于破坏固有的自然联系性。好的变形是既能改变能指的"形态",又能让所指发生意义变迁,获致更具喻指意义的深度——变意。变形大体呈现出优美与怪诞两大系列。为纠偏过分的变形,有人以现象学为根据提出不变形或少变形,乃至反变形观点。但不管变形的多与少,其成功与否,最终还得接受张力与诗意的检验。

网络词语语义变迁初探

网络用语作为网民交流的工具，已经受到了人们的广泛关注。本文研究表明，众多日常词汇的意义在网络交流中发生了一定程度的变迁，主要集中在音变、形变和义变三种方式上。

浅谈英语词素

词素是构成单词的不能分割的有意义的语言单位。它分为自由词素和粘着词素、词根和词缀。

俄语成语的认知与教学

俄语成语是具有独特民族文化内涵的一种形象生动的语言手段,在言语交际中起着一般自由词组无法替代的作用。成语以一种原型结构的方式存在于语言中,既包括典型的原型形式,也包括各种常见或不常见的变体形式,甚至是作者临时独创的仿拟形式。成语的可变性反映出人类对语言单位认知和运用的特点,各种变体丰富着成语的内涵和应用功能。借助认知语言学理论可以发现和更好地理解成语形变和意变这两种方向,以及其变化的限度,有利于指导成语的课堂教学。

论青阳腔的人文背景、历史地位及美学价值(下)

本文将青阳腔声腔音乐的内部结构与规律的探讨和外部形态相结合，借鉴多门学科，从各个视野、各个角度来综观青阳腔的产生、发展、演变以及对其他声腔的影响，并就其在当时社会文化生活中的作用、在申国戏曲音乐发展史上的地位、和戏曲音乐自身的美学价值给予定位。全文分三部分，本期发表的是第三部分，重点论述青阳腔的美学价值，从物达人情、构意更变、时尚滚调等三个层面，分别论述了青阳腔的人性之美、自由之美及通俗、创新之美，力求在前人研究的基础之上，对其审美特征进行总结。

Clinical significance of K-ras and BRAF mutations in Chinese colorectal cancer patients

AIM:To identify and assess mutations in the K-ras and BRAF genes in a cohort of Chinese patients with colorectal cancer (CRC) for their association with various clinicopathological parameters and prognosis.METHODS:Genomic DNA was isolated from frozen tissues.Pyrosequencing analysis was conducted to detect mutations in the K-ras (codons 12,13,and 61) and BRAF genes (codon 600).Statistical analysis was carried out using SPSS-15.0 software.RESULTS:Among the 118 colorectal cancer patients,we detected 41 (34.7%) mutations in the K-ras gene.Mutation frequencies at codon 12 and codon 13 were 23.7% (28/118) and 10.2% (12/118),respectively.Only one patient harbored a point mutation at codon 61 (0.8%,1/118).Gender was the only factor that showed an obvious relationship with K-ras gene mutation (female 44.7% vs male 28.2%,P=0.037).Other clinicopathological features,such as age,location of the tumor,tumor differentiation,Tumor,Node and Metastases classification,and the Union for International Cancer Control staging,showed no positive relationship with K-ras gene mutations.No significant correlation was observed between the presence of K-ras mutations (codons 12,13,and 61) and the survival of the patients.BRAF mutations were rare,and only two patients (1.7%) harbored a detectable mutation at codon 600.CONCLUSION:K-ras gene mutation is a common event in our 118 Chinese CRC patients,with an obvious relationship with gender.However,it seems not to be an independent prognostic factor in CRC patients.The BRAF gene is rarely mutated in Chinese CRC patients.

Clinicopathological significance of B-cell-specific Moloney murine leukemia virus insertion site 1 expression in gastric carcinoma and its precancerous lesion

AIM： To explore the relation between B-cell-specific Moloney murine leukemia virus insertion site 1 （Bmi-1） expression and the clinicopathological features of gastric carcinoma （GC）.METHODS： Immunohistochemistry was used to detect the expression of Bmi-1 and ki-67. Doublelabeling staining was used to display the distribution of Bcl-2^＋/ki-67 cells in 162 cases of GC and its matched normal mucosa and precancerous lesion.RESULTS： The positive rate of Bmi-1 expression in GC（52.5%） was significantly higher than that in normal gastric mucosa （21.6%, X^2 = 33.088, P 〈 0.05）. The Bmi-1 expression in GC was closely related with the Lauren＇s and Borrmann＇s classification and clinicalstage （X^2 = 4.400, 6.122 and 11.190, respectively, P〈 0.05）. The expression of ki-67 was related to the Borrmann＇s classification （X^2 = 13.380, P 〈 0.05）.Bcl-2 expression was correlated with the Lauren＇s classification （Z2 = 4.725, P 〈 0.05）, and the Bmi-1 expression both in GC （rk = 0.157, P 〈 0.05） and inintestinal metaplasia （rk = 0.270, P 〈 0.05）.CONCLUSION： Abnormal Bmi-1 expression in GCmay be involved in cell proliferation, apoptosis andcancerization. This marker can objectively indicate theclinicopathological characteristics of GC.

Understanding Lecturers＇ Well-being From the Aspects of Self-determination Theory

There are five changes in higher education across the world in the 21st century. The five changes include changes in the university students, changes in the professoriate, changes in academic administration, intemationalisation, and assessment of academic work. These changes are evident in higher education in China. The pressure of the changes -on lecturers will have effects on the wellbeing of lecturers. The study discusses the wellbeing under the Self-determination Theory. This theory views wellbeing as a state of happiness. This theory also proposes that people＇s intrinsic goals like personal growth, meaningful relationships, and community contributions can enhance the satisfaction of three basic needs--need for autonomy, need for competence, and need for relatedness. In this way, lecturers can experience a sense of wellbeing. The findings of the study are significant for leaders in higher education who need to implement policies that foster effective work environments.

Clinical significance of HBME-1,Galectin-3,and CK19 expression and the status of BRAF mutation in papillary thyroid carcinoma

Objective The aim of this study was to explore the clinical significance of the expression of proteins human bone marrow endothelial cell markers(HBME-1), Galectin-3, and cytokeratin19(CK19), as well as the status of v-raf murine sarcoma viral oncogene homolog B1(BRAF) mutation in papillary thyroid carcinoma(PTC). Methods Immunohistochemical staining was performed in 82 specimens each of PTC and papillary benign lesions to detect the expression of HBME-1, Galectin-3, and CK19. Polymerase chain reaction(PCR) and gene sequencing were performed on 60 specimens each of PTC and papillary benign lesions to detect the status of BRAF mutation. Results The positive expression ratios of HBME-1, Galectin-3, and CK19 in PTC were 98.8%, 97.6% and 100% respectively, which were significantly higher than the expressions in papillary benign lesions(P < 0.05). No significant relationship was observed between the expression of these makers and the clinicopathological features of PTC. The sensitivity of co-expression of HBME-1 and CK19 or HBME-1 and Galectin-3 as diagnostic criteria of PTC was 99.9%, with a specificity of 95.4%. BRAF mutation was detected in 40 of 60 PTC(66.7%) specimens. There was a statistical difference in BRAF mutations between PTC and papillary benign lesions(P < 0.05); there were no associations between BRAF mutation and the clinicopathological features of PTC. Conclusion Combined immunohistochemical staining of HBME-1, Galectin-3, and CK19 can further improve the sensitivity and specificity of differential diagnosis of PTC. BRAF mutation is a significant genetic event, which may have diagnostic value for PTC.

Clinicopathological significance and relations of Caspase-3 expression, cell proliferation and apoptosis in gastric cancer and the precancerous lesions

Objective： We investigated the relationship between the expression of Caspase-3, cell proliferation and apoptosis in gastric cancer and their precancerous lesions, to explore the tumorigenesis of the stomach mucosa. Methods： Caspase- 3 expression in 13 normal gastric mucosa, 6 chronic atrophic gastritis （CAG）, 31 intestinal metaplasia （IM）, 114 dysplasia （DYS） and 20 gastric carcinomas were investigated immunohistochemically. Cell proliferation was evaluated with anti-Ki-67 immunostaining and apoptosis was evaluated using DNA fragmentation in situ by TdT-mediated dUTP biotin nick end labeling （TUNEL） method. Results： Caspase-3 mild-moderately positive expression was observed in most of normal superficial epithelia, its positively polar distribution in normal mucosa, CAG, IM, DYS and gastric carcinomas changed as seen in TU- NEL, and so did the positive rate. Caspase-3 protein expression showed significantly positive correlation with the number of apoptotic cells labeled with TUNEL （correlation coefficient r = 0,94; P 〈 0101）. Ki-67 expression showed a negative but not significant correlation trend with Caspase-3 （correlation coefficient r = -0.23; P 〉 0.05）. Conclusion： Caspase-3 protein expression was up-regulated from CAG to IM and mild-moderate atypical dysplasia, but down-regulated in severe dysplasia and gastric carcinoma, indicating that inactivity or reduced expression of Caspase-3 is closely correlated with carcinogenesis of the stomach mucosa.

The Influence of Market and Company Characteristics on Voluntary Disclosure

In this paper, the determinants of the voluntary disclosure level of firms have been investigated during a period of deep financial crisis. Two disclosure indexes used as dependent variables are proposed： a global index based on both quantitative and qualitative disclosure and a solely quantitative voluntary index. Firstly, the explanatory variables have been selected taking into account the main contributions of international literature. In addition, some specific variables have been introduced in order to take into account the peculiarities of Italian market system and the ongoing financial crisis. A positive relationship has been found among the global voluntary disclosure （GVD） and the number of employees, the dividend policy, and the presence of independent directors on the board. On the contrary, a negative correlation with respect to the percentage of the firm＇s outstanding shares held by directors （not independent） exists. With reference to the quantitative voluntary disclosure （QVD） index, there is a positive correlation with the number of employees, the dividend policy, the market floating, and the incidence of intangible assets. Moreover, such （quantitative） a disclosure is different depending on the industrial membership sector.

Change and Signif icance of Mitochondrial DNA Copy Number in Esophageal Squamous Cell Carcinoma

OBJECTIVE To compare the differences of mitochondrial DNA (mtDNA) copies among the tissues of esophageal squamous cell carcinoma (ESCC), para-neoplastic tissue and normal mucous membrane of the esophagus, and to study the relationship between the mtDNA and the occurrence and devel- opment of esophageal squamous cell carcinoma. METHODS The mtDNA copies of 42 specimens with the ESCC, paraneoplastic mucous tissue and normal mucous membrane of the esophagus were determined using real-time fluorescence quantitative PCR. The mtDNA was analyzed using agarose gel electrophoresis. RESULTS The mtDNA from all of the tissues (42/42) from the ESCC, para-neoplastic tissue and normal esophageal mucous membranes was analyzed, showing that there were an average mtDNA copy number of 27.1894×106 μg DNA, 9.4102×106 μg DNA and 5.9347×106 μg DNA, from the respective tissues. There were signifi cant differences (F=27.83, P<0.05) in mtDNA copy number among the three. A positive band was shown at 403 bp after gel electrophoresis of the PCR products, and the lane where the ESCC mtDNA located was rather bright, which was in accordance with the result of the real-time PCR determination. CONCLUSION An increase in the mtDNA copy number is related to the occurrence and development of ESCC.

SHRIMP zircon U-Pb dating of a small tonalite intrusion in metamorphic belt of Chinese Altai orogen and its geological implication

Small granitic intrusions occur in the progressive metamorphic belts of the Chinese Ahai orogen. SHRIMP U-Pb analyses were performed on zircons separated from a tonalite intrusion and yielded a concordant age of 409.6±3.7 Ma （ MSWD = 0.93 ）, restricting the emplacement and crystallization of the tonalite intru- sion to the Early Devonian. Combined with the existing geological data of the contemporary large granitic plutons in the Chinese Altai orogen, the tonalite is considered to be formed together with other granitic rocks in a continental arc setting. The tonalite intrusion has consistent foliation with its country rocks, indicating the strain resuiting in the regional deformation should be very strong during or after the early Devonian.

Legal thinking under legal globalization and social transformation

China now is in an important period of social transformation, it puts forward unique requirements for changes from the ethics community to the legal social, and also for law operation, legal developments and public awareness of the laws. Law globalization both is a result of globalization in other areas, but also a tool to promote other areas of globalization, and its essence is the performance of the laws of all countries in the world being more interdependent to further strengthen. From a legal point to analysis, to identify the root causes and find ways to solve and to provide a useful reference for the current socialist harmonious society is very necessary.

Clinical Significance of p53, Proliferating Cell Nuclear Antige and bcl-2 Expression in Bladder Transitional Cell Carcinoma

Objective: To correlate the frequency of p53 mutations, bcl-2 expression and the proliferation status (proliferating cell nuclear antigen, PCNA) in patients with bladder cancer with cell proliferation, apoptosis and their clinico-pathologic ?ndings. Methods: Para?n-embedded sections from 39 super?cial (T1G1-G3) and 23 invasive (T2-T4a G3 N0M0) primary transitional cell carcinomas (TCC) in the bladder were investigated immunohistochemically for p53, bcl-2 and PCNA. The median follow-up was 37 months; 24 had recurrences. The proliferation index (PI) was expressed as a percentage of the PCNA-positive cells in the tumor cells. Apoptosis was detected by terminal deoxy-nucleotidyl transferase-mediated dUTP-biotin nick end labeling (TUNEL), and the apoptotic index (AI) was expressed as a percentage of the TUNEL- positive tumor cells. Results: P53 mutation was identi?ed in 50 patients (80.6%). The mutation was most common in tumors of grade 3 (91.3%) as compared to grade 2 (78.5%) and grade 1 (72.7%, P<0.05). Stage pT2 tumors had a higher frequency of p53 mutation (95.7%) as compared to pTa-1 tumors (74.3%, P<0.01). Only 14 tumors (22.5%) expressed bcl-2; grade 3 tumors expressed bcl-2 signi?cantly more frequently (P<0.05); there was no correlation between bcl-2 and tumor stage. There was no interrelation between p53 mutation and bcl-2 expression (P>0.05). The PI ranged from 17.2% to 41.8% (median 22.4%) and the AI from 1.9% to 3.5% (median 2.9%) in bladder cancer. Statistical analyses revealed a close associations between PI, AI and tumor grade and stage of bladder cancer. Conclusion: P53 mutation correlates with invasion. P53 and PCNA overexpression may o?er valuable additional prognostic information in bladder tumors. With the progression of the tumor grade, cell proliferation may be accompanied by frequent apoptosis in bladder cancer, but the PI increased much more than the AI.

An Anyon Model in a Toric Honeycomb Lattice

We study an anyon model in a toric honeycomb lattice. The ground states and the low-lying excitations coincide with those of Kitaev toric code model and then the excitations obey mutual semionic statistics. This model is helpful to understand the toric code of anyons in a more symmetric way. On the other hand, there is a direct relation between this toric honeycomb model and a boundary coupled Ising chain array in a square lattice via Jordan-Wigner transformation. We discuss the equivalence between these two models in the low-lying sector and realize these anyon excitations in a conventional fermion system. The analysis for the ground state degeneracy in the last section can also be thought of as a complementarity of our previous work [Phys. A： Math. Theor. 43 （2010） 105306].

Remarks on Definitions of Perturbation in General Relativity

There are two kinds of definitions of perturbation of physical quantities in the framework of general relativity： one is direct, the other is geometrical. Correspondingly, there are two types of gauge transformation related with these two definitions. The passive approach is based on the property of general covariance, and the active one is through the action of Lie-derivative. Although under a proper coordinate choice, the two approaches seem to agree with each other, they are different in nature. The geometrical definition of relativistic perturbation and the active approach for gauge transformation are more rigorous in mathematics and less confusing in physical explanation. The direct definition, however, seems to be plagued with difficulties in physical meaning, and the passive approach is more awkward to use, especially for high-order gauge transformations.

Approximate Analytical Solutions for Scattering States of D-dimensional Hulthen Potentials

Using the exponential function transformation approach along with an approximation for the centrifugal potential, the radial Schr6dinger equation of D-dimensional Hulthen potential is transformed to a hypergeometric differential equation. The approximate analytical solutions of scattering states are attained. The normalized wave functions expressed in terms of hypergeometrie functions of scattering states on the ＂k/2π scale＂ and the calculation formula of phase shifts are given. The physical meaning of the approximate analytical solutions is discussed.