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Cu^(2+)/Zn^(2+)对牛血清白蛋白-盐酸小檗碱结合过程的变构效应 被引量:1
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作者 李磊 徐列兵 +1 位作者 陈世云 赵英杰 《化学与生物工程》 CAS 2012年第10期61-66,70,共7页
分别采用荧光光谱(FS)、紫外可见吸收光谱(UV-Vis)以及圆二色谱(CD)考察了2种金属离子Cu2+、Zn2+对牛血清白蛋白(BSA)-盐酸小檗碱(BC)结合过程的变构效应,得到表征BSA内源荧光猝灭、BSA-BC复合物稳定性、BC在BSA分子上的结合位点数发生... 分别采用荧光光谱(FS)、紫外可见吸收光谱(UV-Vis)以及圆二色谱(CD)考察了2种金属离子Cu2+、Zn2+对牛血清白蛋白(BSA)-盐酸小檗碱(BC)结合过程的变构效应,得到表征BSA内源荧光猝灭、BSA-BC复合物稳定性、BC在BSA分子上的结合位点数发生变构的定量变构系数βQ、βA、βn。结果表明,Cu2+/Zn2+对BC猝灭BSA内源荧光呈正变构效应(βQ>1),且变构效应随Cu2+/Zn2+浓度的增大呈现一定的饱和性;而对BSA-BC复合物稳定性以及BC在BSA分子上的结合位点数呈负变构效应(0<βA<1,0<βn<1),且变构效应随Cu2+/Zn2+浓度的增大呈现不同变化趋势;BSA分子构象转变可能是产生变构效应的主要原因。 展开更多
关键词 变构效应 变构系数 金属离子 牛血清白蛋白 盐酸小檗碱 荧光猝灭 结合过程
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牛血清白蛋白-Cu^(2+)结合过程中盐酸小檗碱的变构效应 被引量:3
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作者 刘雪锋 李磊 方云 《化学学报》 SCIE CAS CSCD 北大核心 2008年第17期1967-1973,共7页
用核磁共振(1HNMR)、圆二色谱(CD)、荧光光谱(FS)以及紫外光谱(UV)技术考察了中药有效成分盐酸小檗碱(BC)对牛血清白蛋白(BSA)-Cu2+结合过程的变构效应,得到分别表征BSA内源荧光猝灭、BSA-Cu2+复合物稳定性以及Cu2+在BSA分子上的结合位... 用核磁共振(1HNMR)、圆二色谱(CD)、荧光光谱(FS)以及紫外光谱(UV)技术考察了中药有效成分盐酸小檗碱(BC)对牛血清白蛋白(BSA)-Cu2+结合过程的变构效应,得到分别表征BSA内源荧光猝灭、BSA-Cu2+复合物稳定性以及Cu2+在BSA分子上的结合位点发生变构的定量效应参数βQ(βA和βn)和效率参数γQ(γA和γn).结果表明,BC对Cu2+猝灭BSA内源荧光呈负变构效应(0<βQ<1),而对BSA-Cu2+复合物稳定性以及Cu2+在BSA分子上的结合位点呈正变构效应(βA>1,βn>1);变构效应随BC浓度增加而增强,BC对BSA-Cu2+复合物稳定性的变构效率明显高于其对荧光猝灭和结合位点的变构;BSA分子构象转变是变构效应的主要原因. 展开更多
关键词 变构效应 变构系数 变构效率系数 盐酸小檗碱 牛血清白蛋白
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New Soliton-like Solutions and Multi-soliton Structures for Broer-Kaup System with Variable Coefficients
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作者 JI Ming-Jun Lü Zhuo-Sheng 《Communications in Theoretical Physics》 SCIE CAS CSCD 2005年第5X期802-806,共5页
By using the further extended tanh method [Phys. Lett. A 307 (2003) 269; Chaos, Solitons & Fractals 17 (2003) 669] to the Broer-Kaup system with variable coefficients, abundant new soliton-like solutions and mult... By using the further extended tanh method [Phys. Lett. A 307 (2003) 269; Chaos, Solitons & Fractals 17 (2003) 669] to the Broer-Kaup system with variable coefficients, abundant new soliton-like solutions and multl-solitonlike solutions are derived. Based on the derived multi-soliton-like solutions which contain arbitrary functions, some interesting multi-soliton structures are revealed. 展开更多
关键词 further extended tanh method soliton-like solution
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Spectral-domain dyadic Green’s functions in chiral media
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作者 仲海洋 秦治安 +1 位作者 姚丽 陈宝玖 《Journal of Harbin Institute of Technology(New Series)》 EI CAS 2009年第6期827-829,共3页
A novel method of deriving the electromagnetic dyadic Green's functions in an unbounded, lossless, reciprocal and homogeneous chiral media described by the constitutive relations D = εE + jγB and H = jγE + μ^-1... A novel method of deriving the electromagnetic dyadic Green's functions in an unbounded, lossless, reciprocal and homogeneous chiral media described by the constitutive relations D = εE + jγB and H = jγE + μ^-1B - (ωε)^-1γJ is given. The divergenceless and irrotational splitting of dyadic Dirac 8 function and Fourier transformation are used to directly obtain the divergenceless and irrotational component of spectral-domain dyadic Green's functions in chiral media. This method avoids using the dyadic Green's function eigenfunction expansion technique. The method given here can be generalized to a source-free region and an achiral case. 展开更多
关键词 electromagnetic dyadic Green's function divergenceless component irrotational component dyadic Dirac δ function Fourier transformation
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Research on IPv6 Transition Evolvement and Security Architecture of Smart Distribution Grid Data Communication System
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作者 Xin Miao Xi Chen 《Journal of Energy and Power Engineering》 2012年第1期146-149,共4页
Smart distribution grid needs data communication systems as a support to complete their important functions. The smart distribution grid of the data and information are increasingly adopting internet protocol and Ethe... Smart distribution grid needs data communication systems as a support to complete their important functions. The smart distribution grid of the data and information are increasingly adopting internet protocol and Ethernet technology. The IP addresses are more and more important for the smart distribution grid equipment. The current IPv4 protocol occupies a dominant position; therefore, the challenges of the evolution to IPv6 and network security are faced by data communication systems of the smart distribution grid. The importance of data communications network and its main bearer of business were described. The data communications network from IPv4 to IPv6 evolution of the five processes and four stages of the transition were analyzed. The smart distribution grid data communications network security and types of their offensive and defensive were discussed. And the data communications network security architecture was established. It covers three dimensions, the security level, the communications network security engineering and the communications network security management. The security architecture safeguards the evolution to IPv6 for the smart distribution grid data communication systems. 展开更多
关键词 Smart distribution grid data communication NETWORK IPV6 transition evolvement safety threaten security architecture.
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Fuzzy Sliding Mode Control for a Discrete Servo System
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作者 王传江 孙秀娟 《Journal of Measurement Science and Instrumentation》 CAS 2011年第1期81-83,共3页
A discrete fuzzy sliding mode variable structure controller was studied and designed for a class of electro-hydraulic servo system by means of the combination of sliding mode control theory and fuzzy control theory. D... A discrete fuzzy sliding mode variable structure controller was studied and designed for a class of electro-hydraulic servo system by means of the combination of sliding mode control theory and fuzzy control theory. Designed based on the exponential reaching law, paratmter e of conventional sliding mode controller is the key factor of system chattering, and is ~onal to it as well. In view of this, fuzzy control theory was introduced into the design to ensure the real- time adjusting of parameter e. Sinmlation results show that the sys tem chattering is eliminated perfectly, and the dynamic performance of the control system is improved effectively. 展开更多
关键词 sliding mate control fuzzy control reaching law servo system
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The influence of Cretaceous paleolatitude variation of the Tethyan Himalaya on the India-Asia collision pattern 被引量:6
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作者 ZHANG Ye HUANG BaoChun 《Science China Earth Sciences》 SCIE EI CAS CSCD 2017年第6期1057-1066,共10页
Identifying when, where, and how India and Asia collided is a prerequisite to better understand the evolution of the Himalayan-Tibetan Plateau. Whereas with essentially the same published paleomagnetic data, a large r... Identifying when, where, and how India and Asia collided is a prerequisite to better understand the evolution of the Himalayan-Tibetan Plateau. Whereas with essentially the same published paleomagnetic data, a large range of different India-Asia collision models have been proposed in the literature. Based upon the premise of a northwards-moving Indian plate during the Cretaceous times, we analyze the significant variations in relative paleolatitude produced by a nearly 90° counterclockwise(CCW)rotation of the plate itself during the Cretaceous. Interestingly, recent studies proposed a dual-collision process with a Greater India basin or post-Neo-Tethyan ocean for the India-Asia collision, mainly in the light of divergent Cretaceous paleolatitude differences of the Tethyan Himalaya between the observed values and expected ones computed from the apparent polar wander path of the Indian plate. However, we find that these varied paleolatitude differences are mainly resulted from a nearly 90° CCW rotation of a rigid/quasi-rigid Greater Indian plate during the Cretaceous. On the other hand, when the Indian craton and Tethyan Himalaya moved as two individual blocks rather than a united rigid/quasi-rigid Greater Indian plate before the India-Asia collision, current available Cretaceous paleomagnetic data permit only multiple paleogeographic solutions for the tectonic relationship between the Indian plate and the Tethyan Himalayan terrane. We therefore argue that the tectonic relationship between the Indian plate and the Tethyan Himalayan terrane cannot be uniquely constrained by current paleomagnetic data in the absence of sufficient geological evidence, and the so-called Greater India basin model is just one of the ideal scenarios. 展开更多
关键词 India-Asia collision model Tethyan Himalaya Apparent polar wander (APW) path Paleolatimde Vertical-axis rotation
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Design and implementation of a software architecture for 3D-DDA 被引量:1
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作者 CHENG XiaoLong XIAO Jun +1 位作者 MIAO QingHai WANG Ying 《Science China(Technological Sciences)》 SCIE EI CAS CSCD 2015年第9期1604-1608,共5页
The three-dimensional discontinuous deformation analysis(3D-DDA) is a promising numerical method for both static and dynamic analyses of rock systems. Lacking mature software, its popularity is far behind its ability.... The three-dimensional discontinuous deformation analysis(3D-DDA) is a promising numerical method for both static and dynamic analyses of rock systems. Lacking mature software, its popularity is far behind its ability. To address this problem, this paper presents a new software architecture from a software engineering viewpoint. Based on 3D-DDA characteristics, the implementation of the proposed architecture has the following merits. Firstly, the software architecture separates data, computing, visualization, and signal control into individual modules. Secondly, data storage and parallel access are fully considered for different conditions. Thirdly, an open computing framework is provided which supports most numerical computing methods; common tools for equation solving and parallel computing are provided for further development. Fourthly, efficient visualization functions are provided by integrating a variety of visualization algorithms. A user-friendly graphical user interface is designed to improve the user experience. Finally, through a set of examples, the software is verified against both analytical solutions and the original code by Dr. Shi Gen Hua. 展开更多
关键词 3D-DDA software architecture 3D-DDA data structure open computing framework efficient visualization
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The Coefficient Invariant and Linking Number of Link with Two Components
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作者 Huaan Wu 《Journal of Systems Science and Information》 2006年第3期543-546,共4页
If L is a link with two components and S1,S2…, Sn a switching sequence such that SnSn-1…S1L is unlinked, it is proved that lk(L) =∑i=1^nεi(L) and any link L can be transformed a n-twisting L~ by switching s... If L is a link with two components and S1,S2…, Sn a switching sequence such that SnSn-1…S1L is unlinked, it is proved that lk(L) =∑i=1^nεi(L) and any link L can be transformed a n-twisting L~ by switching some crossings with the linking number:lk(L)=∑i=1^mεiC(EiL)+n 展开更多
关键词 LINK switching sequence link number
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Planar bi-metallic lattice with tailorable coefficient of thermal expansion
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作者 Mengchuan Xu Zeang Zhao +4 位作者 Panding Wang Yijin Zhang Xiaogang Guo Hongshuai Lei Daining Fang 《Acta Mechanica Sinica》 SCIE EI CAS CSCD 2022年第7期192-200,I0005,共10页
A mechanical metamaterial that has a tailorable coefficient of thermal expansion(CTE)is promising for guaranteeing the reliability of electrical and optical instruments under thermal fluctuations.Despite growing resea... A mechanical metamaterial that has a tailorable coefficient of thermal expansion(CTE)is promising for guaranteeing the reliability of electrical and optical instruments under thermal fluctuations.Despite growing research on the design and manufacturing of metamaterials with extraordinary CTEs,it remains challenging to achieve a nearly isotropic tailorable CTE while ensuring a sufficient load bearing capacity for applications,such as mechanical supporting frames.In this research,we propose a type of bi-metallic lattice whose CTE is artificially programmed from positive(75 ppm/K)to negative(−45 ppm/K),and whose equivalent modulus can be as high as 80 MPa.The bi-metallic lattice with a tailorable CTE in two orthogonal directions can be readily assembled without special modifications to construct large-scale planar structures with desired isotropic CTEs.A theoretical model that considers the actual configuration of the bi-metallic joint is developed;the model precisely captures the thermal deformations of lattice structures with varied geometries and material compositions.Guided by our theoretical design method,planar metallic structures that were manufactured using Al,Ti,and Invar alloy were experimentally characterized;the structures exhibited outstanding performance when compared with typical engineering materials. 展开更多
关键词 Mechanical metamaterial Metallic lattice Coefficient of thermal expansion Load bearing capacity
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