Varying-coefficient models are a useful extension of classical linear model. They are widely applied to economics, biomedicine, epidemiology, and so on. There are extensive studies on them in the latest three decade y...Varying-coefficient models are a useful extension of classical linear model. They are widely applied to economics, biomedicine, epidemiology, and so on. There are extensive studies on them in the latest three decade years. In this paper, many of models related to varying-coefficient models are gathered up. All kinds of the estimation procedures and theory of hypothesis test on the varying-coefficients model are summarized. Prom my opinion, some aspects waiting to study are proposed.展开更多
A heterotrophic acidothermophilic bacterial strain,YNTC-1,was isolated from an acidic hot spring in Tengchong,Yunan,China.YNTC-1 grows at pH value of 1.5-8.0 and temperature of 40-70℃,with optimal pH and temperature ...A heterotrophic acidothermophilic bacterial strain,YNTC-1,was isolated from an acidic hot spring in Tengchong,Yunan,China.YNTC-1 grows at pH value of 1.5-8.0 and temperature of 40-70℃,with optimal pH and temperature at 3.0 and 55℃,respectively.The cells of the strain are in shape of short rod,with 1.0-1.2μm in length and 0.7-0.8μm in diameter,and with distinct spores at both poles of each cell.The predominant fatty acids in cellular membrane of the strain are C18:1ω7c.16s rRNA gene analysis reveals that this strain is closely related to Alicyclobacillus sendaiensis,with over 99%sequence similarity.Based on phenotypic and genotypic analyses,YNTC-1 is identified as a member of A.sendaiensis.Considering some important morphological and biochemical differences between strain YNTC-1 and A.sendaiensis ATCC 27009T,YNTC-1 may be proposed to be a novel subspecies of A.sendaiensis.However,this viewpoint has to be confirmed by further studies.Co-bioleaching of pyrite and chalcopyrite with strain YN22,Sulfobacillus thermosulfidooxidans,shows that strain YNTC-1 has no evident influence on bioleaching rates of these two sulphide minerals.展开更多
118 clinical strains of Shigella were serotyped, in which 116 strains were tested to be S. flexneri. The susceptibilities of the S .flexneri strains to quinolones were measured by the disk-diffusion method. It was fou...118 clinical strains of Shigella were serotyped, in which 116 strains were tested to be S. flexneri. The susceptibilities of the S .flexneri strains to quinolones were measured by the disk-diffusion method. It was found that most S .flexneri strains were susceptible to norfloxacin and ciprofloxacin, but resistant to nalidixic acid. To study the correlation between gyrA mutations and quinolones resistance, a fragment within the gyrA gene was amplified by PCR. The SSCP （Single-Strand Conformation Polymorphism） analysis was applied to detect mutations in PCR products of different strains. The mutations were then confirmed by DNA sequencing. Altogether, two types of mutation were revealed, in which one type was single mutation （ C42-T）, and the other was double mutations （ C42-T and A54- G）. By statistical analysis, C42-T （encoding Ser83-keu substitution） was shown to have correlation with nalidixic-acid resistance in the clinical strains of Shigella, while A54-G （encoding Asp87-Gly substitution） was shown to have correlations with both norfloxacin resistance and ciprofloxacin resistance.展开更多
Changes in vegetation phenology are key indicators of the response of ecosystems to climate change.Therefore,knowledge of growing seasons is essential to predict ecosystem changes,especially for regions with a fragile...Changes in vegetation phenology are key indicators of the response of ecosystems to climate change.Therefore,knowledge of growing seasons is essential to predict ecosystem changes,especially for regions with a fragile ecosystem such as the Loess Plateau.In this study,based on the normalized difference vegetation index(NDVI) data,we estimated and analyzed the vegetation phenology in the Loess Plateau from 2000 to 2010 for the beginning,length,and end of the growing season,measuring changes in trends and their relationship to climatic factors.The results show that for 54.84% of the vegetation,the trend was an advancement of the beginning of the growing season(BGS),while for 67.64% the trend was a delay in the end of the growing season(EGS).The length of the growing season(LGS) was extended for 66.28% of the vegetation in the plateau.While the temperature is important for the vegetation to begin the growing season in this region,warmer climate may lead to drought and can become a limiting factor for vegetation growth.We found that increasedprecipitation benefits the advancement of the BGS in this area.Areas with a delayed EGS indicated that the appropriate temperature and rainfall in autumn or winter enhanced photosynthesis and extended the growth process.A positive correlation with precipitation was found for 76.53% of the areas with an extended LGS,indicating that precipitation is one of the key factors in changes in the vegetation phenology in this water-limited region.Precipitation plays an important role in determining the phenological activities of the vegetation in arid and semiarid areas,such as the Loess Plateau.The extended growing season will significantly influence both the vegetation productivity and the carbon fixation capacity in this region.展开更多
基金Foundation item： Supported by the National Natural Science Foundation of China（10501053） Acknowledgement I would like to thank Henan Society of Applied Statistics for which give me a chance to declare my opinion about the varying-coefficient model.
文摘Varying-coefficient models are a useful extension of classical linear model. They are widely applied to economics, biomedicine, epidemiology, and so on. There are extensive studies on them in the latest three decade years. In this paper, many of models related to varying-coefficient models are gathered up. All kinds of the estimation procedures and theory of hypothesis test on the varying-coefficients model are summarized. Prom my opinion, some aspects waiting to study are proposed.
基金Project(50621063)supported by the Chinese National Natural Science Foundation for Innovative Research GroupsProject(2004CB619201)supported by the Major State Basic Research Development Program of China
文摘A heterotrophic acidothermophilic bacterial strain,YNTC-1,was isolated from an acidic hot spring in Tengchong,Yunan,China.YNTC-1 grows at pH value of 1.5-8.0 and temperature of 40-70℃,with optimal pH and temperature at 3.0 and 55℃,respectively.The cells of the strain are in shape of short rod,with 1.0-1.2μm in length and 0.7-0.8μm in diameter,and with distinct spores at both poles of each cell.The predominant fatty acids in cellular membrane of the strain are C18:1ω7c.16s rRNA gene analysis reveals that this strain is closely related to Alicyclobacillus sendaiensis,with over 99%sequence similarity.Based on phenotypic and genotypic analyses,YNTC-1 is identified as a member of A.sendaiensis.Considering some important morphological and biochemical differences between strain YNTC-1 and A.sendaiensis ATCC 27009T,YNTC-1 may be proposed to be a novel subspecies of A.sendaiensis.However,this viewpoint has to be confirmed by further studies.Co-bioleaching of pyrite and chalcopyrite with strain YN22,Sulfobacillus thermosulfidooxidans,shows that strain YNTC-1 has no evident influence on bioleaching rates of these two sulphide minerals.
文摘118 clinical strains of Shigella were serotyped, in which 116 strains were tested to be S. flexneri. The susceptibilities of the S .flexneri strains to quinolones were measured by the disk-diffusion method. It was found that most S .flexneri strains were susceptible to norfloxacin and ciprofloxacin, but resistant to nalidixic acid. To study the correlation between gyrA mutations and quinolones resistance, a fragment within the gyrA gene was amplified by PCR. The SSCP （Single-Strand Conformation Polymorphism） analysis was applied to detect mutations in PCR products of different strains. The mutations were then confirmed by DNA sequencing. Altogether, two types of mutation were revealed, in which one type was single mutation （ C42-T）, and the other was double mutations （ C42-T and A54- G）. By statistical analysis, C42-T （encoding Ser83-keu substitution） was shown to have correlation with nalidixic-acid resistance in the clinical strains of Shigella, while A54-G （encoding Asp87-Gly substitution） was shown to have correlations with both norfloxacin resistance and ciprofloxacin resistance.
基金supported by the“Strategic Priority Research Program-Climate Change:Carbon Budget and Relevant Issues’’of the Chinese Academy of Sciences(Grant No.XDA05060104)
文摘Changes in vegetation phenology are key indicators of the response of ecosystems to climate change.Therefore,knowledge of growing seasons is essential to predict ecosystem changes,especially for regions with a fragile ecosystem such as the Loess Plateau.In this study,based on the normalized difference vegetation index(NDVI) data,we estimated and analyzed the vegetation phenology in the Loess Plateau from 2000 to 2010 for the beginning,length,and end of the growing season,measuring changes in trends and their relationship to climatic factors.The results show that for 54.84% of the vegetation,the trend was an advancement of the beginning of the growing season(BGS),while for 67.64% the trend was a delay in the end of the growing season(EGS).The length of the growing season(LGS) was extended for 66.28% of the vegetation in the plateau.While the temperature is important for the vegetation to begin the growing season in this region,warmer climate may lead to drought and can become a limiting factor for vegetation growth.We found that increasedprecipitation benefits the advancement of the BGS in this area.Areas with a delayed EGS indicated that the appropriate temperature and rainfall in autumn or winter enhanced photosynthesis and extended the growth process.A positive correlation with precipitation was found for 76.53% of the areas with an extended LGS,indicating that precipitation is one of the key factors in changes in the vegetation phenology in this water-limited region.Precipitation plays an important role in determining the phenological activities of the vegetation in arid and semiarid areas,such as the Loess Plateau.The extended growing season will significantly influence both the vegetation productivity and the carbon fixation capacity in this region.
