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口服耐受机制的研究进展
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作者 虞涛 《泸州医学院学报》 1999年第2期171-173,共3页
关键词 口服耐受机制 研究进展 抗原呈递
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肠道粘膜免疫研究进展 被引量:31
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作者 吴翰桂 朱诚 丁仁瑞 《免疫学杂志》 CAS CSCD 北大核心 2000年第3期235-238,共4页
肠道粘膜免疫是机体防御感染的第一防线 ,而肠道炎症与口服耐受机制的研究更具有理论与临床的实际意义。对此领域的研究已成为免疫学中的一个热点。据此 ,本文对小肠上皮内淋巴细胞的来源和功能 ,肠道慢性炎症的发生 。
关键词 小肠IEL 肠道粘膜免疫 口服耐受机制
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New aspects in celiac disease 被引量:10
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作者 MI Torres MA López Casado A Ríos 《World Journal of Gastroenterology》 SCIE CAS CSCD 2007年第8期1156-1161,共6页
Celiac disease (CD) is a common autoimmune disorder characterized by an immune response to ingested gluten and has a strong HLA association with HLA- DQ2 and HLA-DQ8 molecules, but human HLA-DQ risk factors do not exp... Celiac disease (CD) is a common autoimmune disorder characterized by an immune response to ingested gluten and has a strong HLA association with HLA- DQ2 and HLA-DQ8 molecules, but human HLA-DQ risk factors do not explain the entire genetic susceptibility to gluten intolerance. CD is caused by the lack of immune tolerance (oral tolerance) to wheat gluten. In this sense, the expression of soluble HLA-G in CD is of special interest because the molecule plays an important role in the induction of immune tolerance. The enhanced expression of soluble HLA-G found in CD may be part of a mechanism to restore the gluten intolerance. In this editorial, we review recent progress in understanding CD in relation to its prevalence, diagnosis and possible mechanisms of pathogenesis. 展开更多
关键词 Celiac disease Oral tolerance IL-10 TGF-BETA Gluten intolerance
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