目的探究对中重度斑块型银屑病患者使用可善挺的治疗效果。方法便利选取2020年1月—2023年1月南平市疾病预防控制中心收治的64例中重度斑块型银屑病患者为研究对象,按随机数表法分为两组。对照组32例患者口服阿维A,外用卡泊三醇治疗,研...目的探究对中重度斑块型银屑病患者使用可善挺的治疗效果。方法便利选取2020年1月—2023年1月南平市疾病预防控制中心收治的64例中重度斑块型银屑病患者为研究对象,按随机数表法分为两组。对照组32例患者口服阿维A,外用卡泊三醇治疗,研究组32例患者使用可善挺治疗。比较两组用药后第2周、第6周以及第12周的严重度指数(Psoriasis Area and Severity Index,PASI)应答率、特殊部位受累应答率,停药后复发时间。结果研究组第2周PASI应答率(21.88%)、第6周PASI应答率(68.75%)、第12周PASI应答率(96.88%)高于对照组,差异有统计学意义(χ^(2)=5.143、18.515、13.166,P均<0.05)。研究组第6、12周特殊部位受累应答率高于对照组,差异有统计学意义(P均<0.05)。研究组停药后复发时间长于对照组,差异有统计学意义(P<0.05)。结论中重度斑块型银屑病患者使用可善挺治疗效果显著,在相同的治疗周期内,可善挺可明显减轻皮损面积与严重程度,停药后复发的时间较传统治疗明显延后。展开更多
Despite widespread concerns and elevated policy debates, little is known about the Chinese public's perceptions of water pollution and willingness to cooperate with government policies. Based on survey data, this stu...Despite widespread concerns and elevated policy debates, little is known about the Chinese public's perceptions of water pollution and willingness to cooperate with government policies. Based on survey data, this study examined Lake Tai resident perception of water pollution, willingness to pay (WTP) for water quality improvements, and its influencing factors. Contingent valuation (CV) results showed that respondents would prefer to pay 141 CNY per household a year, approximately 0.70% of their annual per capita disposable income, as an environmental fee to improve water quality in Lake Yai. Aggregate WTP for all five lakeside cities of Lake Tai was estimated at about 3.8 billion CNY, without discounts, in the next ten years. WTP was found to increase with income and female respondents were willing to pay more than males. Those respondents who were dissatisfied with water quality were more likely to pay more. The usage of Lake Tai did not strongly affect WTE展开更多
文摘目的探究对中重度斑块型银屑病患者使用可善挺的治疗效果。方法便利选取2020年1月—2023年1月南平市疾病预防控制中心收治的64例中重度斑块型银屑病患者为研究对象,按随机数表法分为两组。对照组32例患者口服阿维A,外用卡泊三醇治疗,研究组32例患者使用可善挺治疗。比较两组用药后第2周、第6周以及第12周的严重度指数(Psoriasis Area and Severity Index,PASI)应答率、特殊部位受累应答率,停药后复发时间。结果研究组第2周PASI应答率(21.88%)、第6周PASI应答率(68.75%)、第12周PASI应答率(96.88%)高于对照组,差异有统计学意义(χ^(2)=5.143、18.515、13.166,P均<0.05)。研究组第6、12周特殊部位受累应答率高于对照组,差异有统计学意义(P均<0.05)。研究组停药后复发时间长于对照组,差异有统计学意义(P<0.05)。结论中重度斑块型银屑病患者使用可善挺治疗效果显著,在相同的治疗周期内,可善挺可明显减轻皮损面积与严重程度,停药后复发的时间较传统治疗明显延后。
基金Project supported by the National Natural Science Foundation of China (No. 70873107)the National Basic Research Program (973) of China (No. 2005CB121104)
文摘Despite widespread concerns and elevated policy debates, little is known about the Chinese public's perceptions of water pollution and willingness to cooperate with government policies. Based on survey data, this study examined Lake Tai resident perception of water pollution, willingness to pay (WTP) for water quality improvements, and its influencing factors. Contingent valuation (CV) results showed that respondents would prefer to pay 141 CNY per household a year, approximately 0.70% of their annual per capita disposable income, as an environmental fee to improve water quality in Lake Yai. Aggregate WTP for all five lakeside cities of Lake Tai was estimated at about 3.8 billion CNY, without discounts, in the next ten years. WTP was found to increase with income and female respondents were willing to pay more than males. Those respondents who were dissatisfied with water quality were more likely to pay more. The usage of Lake Tai did not strongly affect WTE