牙周引导性组织再生术可降解屏障膜材料的研究

牙周引导性组织再生术的关键是屏障膜材料。屏障膜可分为不可降解性膜与可降解性膜。可降解性屏障膜材料研究较多的有胶原、聚乳酸聚羟基乙酸共聚物。近年来可降解性膜的研究焦点是屏障膜的生物化研究。本文着重对可降解性膜材料的理化性能、生物学特性以及屏障膜的生物化研究作一综述。

骨髓基质细胞与珊瑚人工骨和两种屏障膜生物相容性的实验研究

目的:探讨珊瑚人工骨(natural coral,NC)作为骨组织工程学载体吸附骨髓基质细胞(bone marrowstromalcells,BMSCs)的可行性,并比较两种可降解性屏障膜PLGA-NC复合膜和PLGA膜的生物相容性及用于牙周引导组织再生术的可行性。方法: 体外分离培养狗的BMSCs,检测其成骨活性;将NC和可降解性屏障膜材料分别吸附原代培养的BMSCs,观察复合物的形态,进行细胞蛋白含量测定。结果: BMSCs在NC的孔隙中生长良好,并有细胞基质的分泌;两种屏障膜与细胞均有较好的生物相容性,但PLGA-NC 复合膜较PLGA膜有更多的微孔和更好的成形性。结论: NC可作为牙周骨组织工程学中的细胞载体;PLGA-NC复合膜比单纯的PLGA膜更适合作为牙周引导组织再生的屏障膜材料。

Preparation and Applications of Biodegradable Mulch

[Objective] The aim was to introduce preparation methods of biodegradable mulch of starch, and analyze the comprehensive properties, including structure, me- chanical property and degradation. [Method] Environmental factors of biodegradable mulch of starch and common mulch were collected to make analysis and compar- isons on temperature, ground temperature, and illumination intensity with different mulches. Furthermore, the germination rates of broach bean and garlic were mea- sured with mulches covered. [Result] The comprehensive property of biodegradable mulch of starch performed better. [Conclusion] The biodegradable mulch of starch could reduce environmental pollutions and the application would be recommended.