本文通过对65例20—40岁正常人在西宁地区(海拔2261米)时周围神经传导速度的测定结果为:1.西宁地区与平原资料比较结论均有显著差别。2.潜伏时 P值<0.001,运动神经传导速度 P 值<0.01,显示周围神经潜伏时延长,传导速度减慢,说明...本文通过对65例20—40岁正常人在西宁地区(海拔2261米)时周围神经传导速度的测定结果为:1.西宁地区与平原资料比较结论均有显著差别。2.潜伏时 P值<0.001,运动神经传导速度 P 值<0.01,显示周围神经潜伏时延长,传导速度减慢,说明周围神经传导速度测定对周围神经功能状态的判断和对周围神经疾病的诊断具有特定的临床应用价值。展开更多
Objective: The purpose of this study was to investigate the prevalence of peri pheral neuropathy in patients with β thalas saemia. Methods: Thirty six patie nts with a mean age of 29.2 ±.8.2 years and 17 healthy...Objective: The purpose of this study was to investigate the prevalence of peri pheral neuropathy in patients with β thalas saemia. Methods: Thirty six patie nts with a mean age of 29.2 ±.8.2 years and 17 healthy controls with a mean age of 27.6 ±.9.1 were included in this study. Measurements included the neuropath y symptoms score (NSS), the neuropathy disability score (NDS) as well as nerve c onduction studies of two motor (ulnar and peroneal) and two sensory (ulnar and s ural) nerves of the right limbs. Results: A mainly sensory axonal polyneuropathy was present in 19 out of 36 patients (52.7%). Eight out of these 19 patients a lso had abnormal NDS values. The neuropathy correlated significantly with the ag e of the patients and the hematocrit. However, it did not correlate with the pre sence of antibodies against HCV, the ferritin levels, or with a history of trans fusions, desferrioxamine treatment, or splenectomy. Conclusions: This study show ed a high prevalence of a predominantly sensory neuropathy in patients with β thalassaemia. The electrophysiological data suggest that the underlying patholog y is an axonopathy. Chronic hypoxia of the nerves resulting from severe anaemia may contribute to the pathogenesis of this neuropathy.展开更多
文摘本文通过对65例20—40岁正常人在西宁地区(海拔2261米)时周围神经传导速度的测定结果为:1.西宁地区与平原资料比较结论均有显著差别。2.潜伏时 P值<0.001,运动神经传导速度 P 值<0.01,显示周围神经潜伏时延长,传导速度减慢,说明周围神经传导速度测定对周围神经功能状态的判断和对周围神经疾病的诊断具有特定的临床应用价值。
文摘Objective: The purpose of this study was to investigate the prevalence of peri pheral neuropathy in patients with β thalas saemia. Methods: Thirty six patie nts with a mean age of 29.2 ±.8.2 years and 17 healthy controls with a mean age of 27.6 ±.9.1 were included in this study. Measurements included the neuropath y symptoms score (NSS), the neuropathy disability score (NDS) as well as nerve c onduction studies of two motor (ulnar and peroneal) and two sensory (ulnar and s ural) nerves of the right limbs. Results: A mainly sensory axonal polyneuropathy was present in 19 out of 36 patients (52.7%). Eight out of these 19 patients a lso had abnormal NDS values. The neuropathy correlated significantly with the ag e of the patients and the hematocrit. However, it did not correlate with the pre sence of antibodies against HCV, the ferritin levels, or with a history of trans fusions, desferrioxamine treatment, or splenectomy. Conclusions: This study show ed a high prevalence of a predominantly sensory neuropathy in patients with β thalassaemia. The electrophysiological data suggest that the underlying patholog y is an axonopathy. Chronic hypoxia of the nerves resulting from severe anaemia may contribute to the pathogenesis of this neuropathy.
