浅谈进一步加强山西焦煤集团内部经济责任审计工作

经济责任审计工作在山西焦煤集团公司及各子分公司内部已开展多年,取得了一定的成绩。笔者就其实施过程中的一些问题及其解决方法进行了探讨。

攀钢深度挖潜抓好四季度生产经营

进入四季度以来,攀钢各子分公司（单位）以＂生产经营现金流为正、产品边际贡献为正＂为底线,以＂盈亏平衡＂为红线,充分调动广大干部职工的积极性、主动性和创造性,全面挖潜,全力确保年度生产经营目标实现。攀钢钒引导和激励广大干部职工牢固树立＂质量＂不容妥协经营理念,执行标准,提升质量,智造精品。

Molecular dynamics simulations investigate the long-range effects on TrpR(tryptophan repressor protein)

Molecular dynamics(MD)simulations and anisotropic thermal diffusion dynamics(ATD)simulations were performed on the wild TrpR and its 75 residue mutant(mTrpR)to investigate TrpR longrange effects.The ATD result shows that the mTrpR has higher fluctuation than the wild TrpR,and its helix chainⅡF has particular disorder.It is obvious that the 75 residue of wild TrpR and mTrpR affects the protein dynamics flexibilities by the long-range effects.The ATD and MD both confirm that the differences in the size of side-chain and three-dimensional structures of two different 75 residues in the wild TrpR and mTrpR will spread to the entire protein by way of the long-range effects.Long-range effect affects the protein side chain interaction,conformational changes,flexibilities and secondary structures.Further,the ATD result also shows that each 75 residue of the symmetric homodimer has the same effect,and the two 75 residues have a positive correlation in long-range regulating processes.The residues 48,50,71,79 in chainⅠof wild TrpR and residues 45,72,80 in chainⅡof mTrpR play important roles in long-range interaction processes.

“首家”内控监督平台“开跑”

＂东城区国家税务局内控监督平台运行正常,各子系统操作顺畅……＂2017年10月9日,随着27个基层单位平台成功上线反馈电话打入试运行领导小组办公室,标志着全国＂首家＂内控监督平台在北京市国家税务局成功上线。税务系统内控监督平台是国家税务总局党组全面落实从严治党主体责任、防控税收执法和行政管理风险的重要举措。