Achieving optimal alignment in total knee arthroplasty(TKA) is a critical factor in ensuring optimal outcomes and long-term implant survival. Traditionally, mechanical alignment has been favored to achieve neutral pos...Achieving optimal alignment in total knee arthroplasty(TKA) is a critical factor in ensuring optimal outcomes and long-term implant survival. Traditionally, mechanical alignment has been favored to achieve neutral postoperative joint alignment. However, contemporary approaches, such as kinematic alignments and hybrid techniques including adjusted mechanical, restricted kinematic, inverse kinematic, and functional alignments, are gaining attention for their ability to restore native joint kinematics and anatomical alignment, potentially leading to enhanced functional outcomes and greater patient satisfaction. The ongoing debate on optimal alignment strategies considers the following factors: long-term implant durability, functional improvement, and resolution of individual anatomical variations. Furthermore, advancements of computer-navigated and robotic-assisted surgery have augmented the precision in implant positioning and objective measurements of soft tissue balance. Despite ongoing debates on balancing implant longevity and functional outcomes, there is an increasing advocacy for personalized alignment strategies that are tailored to individual anatomical variations. This review evaluates the spectrum of various alignment techniques in TKA, including mechanical alignment, patient-specific kinematic approaches, and emerging hybrid methods. Each technique is scrutinized based on its fundamental principles, procedural techniques, inherent advantages, and potential limitations, while identifying significant clinical gaps that underscore the need for further investigation.展开更多
Objective To probe into the effects on acute gouty arthritis treated comprehensively with electroacupuncture (EA) and warming moxibustion. Methods 70 cases were randomized into treatment group (48 cases), in which the...Objective To probe into the effects on acute gouty arthritis treated comprehensively with electroacupuncture (EA) and warming moxibustion. Methods 70 cases were randomized into treatment group (48 cases), in which the EA+warming moxibustion was applied; and controlled group (22 cases), in which, colchicine was prescribed for oral administration. Results The statistical outcomes after 1 course treatment in treatment group: 28 cases were cured (58.33%), 18 cases improved (37.50%) and the total effective rate was 95.83%. In controlled group: 12 cases (54.55%) were cured, 8 cases improved (36.36%) and the total effective rate was 90.91%. The therapeutic effects of two groups were basically consistent, without significant different (P>0.05). But, concerning to side effect, there was no any toxic side effects in the group treated with EA+warming moxibustion, and the occurrence rate in the group treated with colchicine was 40.91%. Conclusion Electroacupuncture+warming moxibustion achieves good therapeutic effects without any side effects.展开更多
The effects of heat input on the microstructures and mechanical properties of tungsten inert gas （TIG） butt-welded AZ31/MB3 dissimilar Mg alloys joint were investigated by microstructural observations, microhardness...The effects of heat input on the microstructures and mechanical properties of tungsten inert gas （TIG） butt-welded AZ31/MB3 dissimilar Mg alloys joint were investigated by microstructural observations, microhardness testing and tensile testing. The results reveal that with the increase of heat input, the width of welding seam increases obviously and the grains both in the fusion zone and the heat affected zone coarsen during TIG welding process. The tensile strength of butt-welded joint increases with the increase of heat input and the maximum joining strength of 242 MPa is obtained with wedding current of 90 A. However, lots of welding pores occur with the further increase of heat input, which results in the decrease of joining strength. It is experimentally demonstrated that robust joint can be obtained by TIG welding process.展开更多
Inflammatory bowel diseases(IBDs), particularly Crohn's disease(CD) and ulcerative colitis(UC), are associated with a variety of extra-intestinal manifestations(EIMs).About 36% of IBD patients have at least one EI...Inflammatory bowel diseases(IBDs), particularly Crohn's disease(CD) and ulcerative colitis(UC), are associated with a variety of extra-intestinal manifestations(EIMs).About 36% of IBD patients have at least one EIM, which most frequently affect the joints, skin, eyes and the biliary tract.The EIMs associated with IBD have a negative impact on patients with UC and CD, and the resolution of most of them parallels that of the active IBD in terms of timing and required therapy;however, the clinical course of EIMs such as axial arthritis, pyoderma gangrenosum, uveitis, and primary sclerosing cholangitis is independent of IBD activity.The peripheral and axial arthritis associated with IBD have traditionally been treated with simple analgesics, non-steroidal anti-inflammatory drugs, steroids, sulfasalazine, methotrexate, local steroid injections and physiotherapy, but the introduction of biological response modifi ers such as tumor necrosis factor-α blockers, has led to further improvements.展开更多
Acceleration reflects vibration of a robot,and the vibration signal can reflect the operation state of the robot. Generally,detection of robot mechanical arm failure requires installing sensors on each joint. This stu...Acceleration reflects vibration of a robot,and the vibration signal can reflect the operation state of the robot. Generally,detection of robot mechanical arm failure requires installing sensors on each joint. This study proposes a method to diagnose the fault by single acceleration sensor only,which is installed at the end of the robot. The operation state of the robot is evaluated by analyzing vibration characteristics of its acceleration. First,a data acquisition function of a programmable multi-axis controller is applied to extract practical motion signals of the robot joints during operation,and practical motion signals are analyzed. Second,synthetic methods to determine acceleration of the end joints of SCARA robots in a Cartesian space is used based on the theory of the Jacobian matrix and the frequency domain of final acceleration is investigated. The relationship between end-and joint-vibration frequencies under given speeds is determined. Then,the method is verified by comparing characteristic frequencies of joint acceleration and synthetic acceleration in Cartesian coordinate system at different speeds. Finally,some faults can be diagnosed by comparing the acceleration vibration frequency extracted by a single acceleration sensor installed at the end of robot with the normal running state. Thus,this method can be used to monitor the signal variation of each joint without installing sensors on each robot joint.展开更多
文摘Achieving optimal alignment in total knee arthroplasty(TKA) is a critical factor in ensuring optimal outcomes and long-term implant survival. Traditionally, mechanical alignment has been favored to achieve neutral postoperative joint alignment. However, contemporary approaches, such as kinematic alignments and hybrid techniques including adjusted mechanical, restricted kinematic, inverse kinematic, and functional alignments, are gaining attention for their ability to restore native joint kinematics and anatomical alignment, potentially leading to enhanced functional outcomes and greater patient satisfaction. The ongoing debate on optimal alignment strategies considers the following factors: long-term implant durability, functional improvement, and resolution of individual anatomical variations. Furthermore, advancements of computer-navigated and robotic-assisted surgery have augmented the precision in implant positioning and objective measurements of soft tissue balance. Despite ongoing debates on balancing implant longevity and functional outcomes, there is an increasing advocacy for personalized alignment strategies that are tailored to individual anatomical variations. This review evaluates the spectrum of various alignment techniques in TKA, including mechanical alignment, patient-specific kinematic approaches, and emerging hybrid methods. Each technique is scrutinized based on its fundamental principles, procedural techniques, inherent advantages, and potential limitations, while identifying significant clinical gaps that underscore the need for further investigation.
文摘Objective To probe into the effects on acute gouty arthritis treated comprehensively with electroacupuncture (EA) and warming moxibustion. Methods 70 cases were randomized into treatment group (48 cases), in which the EA+warming moxibustion was applied; and controlled group (22 cases), in which, colchicine was prescribed for oral administration. Results The statistical outcomes after 1 course treatment in treatment group: 28 cases were cured (58.33%), 18 cases improved (37.50%) and the total effective rate was 95.83%. In controlled group: 12 cases (54.55%) were cured, 8 cases improved (36.36%) and the total effective rate was 90.91%. The therapeutic effects of two groups were basically consistent, without significant different (P>0.05). But, concerning to side effect, there was no any toxic side effects in the group treated with EA+warming moxibustion, and the occurrence rate in the group treated with colchicine was 40.91%. Conclusion Electroacupuncture+warming moxibustion achieves good therapeutic effects without any side effects.
基金Project（51575067） supported by the National Natural Science Foundation of China Project（2012ZX04010-081） supported by the Major and Special Project of Ministry of Science and Technology, China
文摘The effects of heat input on the microstructures and mechanical properties of tungsten inert gas （TIG） butt-welded AZ31/MB3 dissimilar Mg alloys joint were investigated by microstructural observations, microhardness testing and tensile testing. The results reveal that with the increase of heat input, the width of welding seam increases obviously and the grains both in the fusion zone and the heat affected zone coarsen during TIG welding process. The tensile strength of butt-welded joint increases with the increase of heat input and the maximum joining strength of 242 MPa is obtained with wedding current of 90 A. However, lots of welding pores occur with the further increase of heat input, which results in the decrease of joining strength. It is experimentally demonstrated that robust joint can be obtained by TIG welding process.
文摘Inflammatory bowel diseases(IBDs), particularly Crohn's disease(CD) and ulcerative colitis(UC), are associated with a variety of extra-intestinal manifestations(EIMs).About 36% of IBD patients have at least one EIM, which most frequently affect the joints, skin, eyes and the biliary tract.The EIMs associated with IBD have a negative impact on patients with UC and CD, and the resolution of most of them parallels that of the active IBD in terms of timing and required therapy;however, the clinical course of EIMs such as axial arthritis, pyoderma gangrenosum, uveitis, and primary sclerosing cholangitis is independent of IBD activity.The peripheral and axial arthritis associated with IBD have traditionally been treated with simple analgesics, non-steroidal anti-inflammatory drugs, steroids, sulfasalazine, methotrexate, local steroid injections and physiotherapy, but the introduction of biological response modifi ers such as tumor necrosis factor-α blockers, has led to further improvements.
基金Supported by the National Natural Science Foundation of China(No.51775284)Natural Science Foundation of Jiangsu Province(BK20151505)Joint Research Fund for Overseas Chinese,Hong Kong and Macao Young Scholars(61728302)
文摘Acceleration reflects vibration of a robot,and the vibration signal can reflect the operation state of the robot. Generally,detection of robot mechanical arm failure requires installing sensors on each joint. This study proposes a method to diagnose the fault by single acceleration sensor only,which is installed at the end of the robot. The operation state of the robot is evaluated by analyzing vibration characteristics of its acceleration. First,a data acquisition function of a programmable multi-axis controller is applied to extract practical motion signals of the robot joints during operation,and practical motion signals are analyzed. Second,synthetic methods to determine acceleration of the end joints of SCARA robots in a Cartesian space is used based on the theory of the Jacobian matrix and the frequency domain of final acceleration is investigated. The relationship between end-and joint-vibration frequencies under given speeds is determined. Then,the method is verified by comparing characteristic frequencies of joint acceleration and synthetic acceleration in Cartesian coordinate system at different speeds. Finally,some faults can be diagnosed by comparing the acceleration vibration frequency extracted by a single acceleration sensor installed at the end of robot with the normal running state. Thus,this method can be used to monitor the signal variation of each joint without installing sensors on each robot joint.
