Objective： The aim of the study was to evaluate the therapeutic effect and safety of whole-course three-dimensional conformal radiotherapy （3DCRT） combined with late-course accelerated hyperfractionated radiothera...Objective： The aim of the study was to evaluate the therapeutic effect and safety of whole-course three-dimensional conformal radiotherapy （3DCRT） combined with late-course accelerated hyperfractionated radiotherapy （LCAFR） on patients with esophageal carcinoma. Methods： one hundred and one patients with esophageal carcinoma were divided into two groups. Observing group （49 cases） were treated by whole-course 3DCRT. Patients in control group （52 cases） were treated by conventional radiotherapy. Clinical efficiencies and radiation toxicities were compared between two groups. Results： The side effects including radiation esophagitis （63.2%） and tracheitis （49.0%） decreased in observing group, but there was no significant difference between two groups （69.2% and 55.7% in controls）. The 1-, 2-and 3-year tumor local control rates and overall survival rates in the observing group were significantly improved compared with the control group, being respectively 87.8%, 75.5%, 63.3% vs 71.2%, 55.8%, 42.3% and 85.7%, 71.4%, 46.7% vs 69.2%, 51.9%, 26.9% （all P 0.05）. Conclusion： The therapeutic effect of whole-course 3DCRT combined with LCAFR for esophageal carcinomas is superior to conventional radiotherapy.展开更多
As watershed algorithm suffers from over-segmentation problem, this paper presented an efficient method to resolve this problem. First, pre-process of the image using median filter is made to reduce the effect of nois...As watershed algorithm suffers from over-segmentation problem, this paper presented an efficient method to resolve this problem. First, pre-process of the image using median filter is made to reduce the effect of noise. Second, watershed algorithm is employed to provide initial regions. Third, regions are merged according to the information between the region and boundary. In the merger processing based on the region information, an adaptive threshold of the difference between the neighboring regions is used as the region merge criteria, which is based on the human visual character. In the merger processing on the boundary information, the gradient is used to judge the true boundary of the image to avoid merging the foreground with the background regions. Finally, post-process to the regions using mathematical morphology open and close filter is done to smooth object boundaries. The experimental results show that this method is very efficient.展开更多
文摘Objective： The aim of the study was to evaluate the therapeutic effect and safety of whole-course three-dimensional conformal radiotherapy （3DCRT） combined with late-course accelerated hyperfractionated radiotherapy （LCAFR） on patients with esophageal carcinoma. Methods： one hundred and one patients with esophageal carcinoma were divided into two groups. Observing group （49 cases） were treated by whole-course 3DCRT. Patients in control group （52 cases） were treated by conventional radiotherapy. Clinical efficiencies and radiation toxicities were compared between two groups. Results： The side effects including radiation esophagitis （63.2%） and tracheitis （49.0%） decreased in observing group, but there was no significant difference between two groups （69.2% and 55.7% in controls）. The 1-, 2-and 3-year tumor local control rates and overall survival rates in the observing group were significantly improved compared with the control group, being respectively 87.8%, 75.5%, 63.3% vs 71.2%, 55.8%, 42.3% and 85.7%, 71.4%, 46.7% vs 69.2%, 51.9%, 26.9% （all P 0.05）. Conclusion： The therapeutic effect of whole-course 3DCRT combined with LCAFR for esophageal carcinomas is superior to conventional radiotherapy.
文摘As watershed algorithm suffers from over-segmentation problem, this paper presented an efficient method to resolve this problem. First, pre-process of the image using median filter is made to reduce the effect of noise. Second, watershed algorithm is employed to provide initial regions. Third, regions are merged according to the information between the region and boundary. In the merger processing based on the region information, an adaptive threshold of the difference between the neighboring regions is used as the region merge criteria, which is based on the human visual character. In the merger processing on the boundary information, the gradient is used to judge the true boundary of the image to avoid merging the foreground with the background regions. Finally, post-process to the regions using mathematical morphology open and close filter is done to smooth object boundaries. The experimental results show that this method is very efficient.
