Objective To explore the correlation of blood glucose variability with the outcome in patients with severe acute stroke.Methods This retrospective clinical study was performed on patients with severe acute stroke.Base...Objective To explore the correlation of blood glucose variability with the outcome in patients with severe acute stroke.Methods This retrospective clinical study was performed on patients with severe acute stroke.Based on the three months mRS score after discharge,they were divided into good outcome groups and poor outcome groups.The blood glucose on admission,mean blood glucose,blood glucose standard deviation,coefficient variation of blood glucose and other clinical data were compared between both groups.Multivariate logistic regression analysis was used to determine the independent predictors of poor outcome in patients with severe acute stroke.Results A total of 420 patients with severe acute stroke were included,207(49.3%)with good outcome groups,213(50.7%)with poor outcome groups.Multivariate logistic regression analysis showed that age,NIHSS score,GCS score,APACHEⅡscore,blood glucose standard deviation,coefficient of variation of blood glucose were independent predictors of poor outcome in patients with severe acute stroke on 3 months after discharge.Conclusion Blood glucose variability are the independent predictors of poor outcome of the three months after discharge in patients with severe acute stroke,the great range of glycemic excursion indicates poor outcome.展开更多
<Abstract>This paper reports the seasonal feature of the relationship between ENSO and the stratospheric Polar Vortex Oscillation (PVO) variability in the Northern Hemisphere.It is shown that the lagged ENSO-PVO...<Abstract>This paper reports the seasonal feature of the relationship between ENSO and the stratospheric Polar Vortex Oscillation (PVO) variability in the Northern Hemisphere.It is shown that the lagged ENSO-PVO coupling relationship exhibits distinct seasonal feature,due to the strong seasonality of PVO and ENSO.Specifically,the PVO variability not only during winter,but also in autumn and spring months,is significantly correlated with ENSO anomalies leading by seasons;however,no significant effect of ENSO is found on the PVO variability in winter months of November and February.Although a significant ENSO effect is primarily observed when ENSO leads PVO by about one year,a significant correlation is also found between PVO in the following spring months (M +1 A +1) and ENSO anomalies in the previous autumn (A-1 S-1 O- 1 N -1) when ENSO anomalies lead by about 18 months.The significant correlation between PVO in various seasons and the corresponding ENSO anomalies leading by seasons could be explicitly verified in most of the individual years,confirming that the lagged ENSO effect can largely modulate the seasonal timescale variability of PVO.Moreover,the composite spatial patterns of the zonal-mean temperature anomalies further show that the ENSO effect on the PVO in various seasons is related to the interannual variability of the seasonal timescale PVO events.展开更多
The somaclone, C39, derived by tissue culture from the obligate apomict Paspalum dilatatum cv Raki (2n=50), had 50 chromosomes and a karyotype apparently identical to Raki.SC2 seedlings of C39 showed a high degree of ...The somaclone, C39, derived by tissue culture from the obligate apomict Paspalum dilatatum cv Raki (2n=50), had 50 chromosomes and a karyotype apparently identical to Raki.SC2 seedlings of C39 showed a high degree of phenotypic variation which was of ten associated with increased chromosome numbers, but some of the variant seedlings were karyotypically indistinguishable from Raki or C39. Plants with increased chromosome numbers exhibited a high degree of intraplant chromosome variation (aneusomaty). In one of the SC2seedlings, the chromosome number of root tip cells varied from 58 to 82 and in several other seedlings the range was more than 10. The results suggested that the ability to form seed apomictically was much reduced in C39 and that this plant showed some capacity for sexual reproduction and the resulting seedlings, with a chromosome number of about 70, were genetically unstable. Of 11 SC2 seedlings examined cytolog ically, 6 did not produce any viable seed. Seedlings grown from seed of the remaining 5 plants showed that aneusomaty persisted in the SC3 generation. SC3 seedlings which were phenotypically similar to their maternal parent showed a similar range of chromosome numbers to that parent. Some of the SC3 seedlings exhibited an even wider range of chromosome numbers (e.g.56-136), and these plants were all dwarfs.展开更多
文摘Objective To explore the correlation of blood glucose variability with the outcome in patients with severe acute stroke.Methods This retrospective clinical study was performed on patients with severe acute stroke.Based on the three months mRS score after discharge,they were divided into good outcome groups and poor outcome groups.The blood glucose on admission,mean blood glucose,blood glucose standard deviation,coefficient variation of blood glucose and other clinical data were compared between both groups.Multivariate logistic regression analysis was used to determine the independent predictors of poor outcome in patients with severe acute stroke.Results A total of 420 patients with severe acute stroke were included,207(49.3%)with good outcome groups,213(50.7%)with poor outcome groups.Multivariate logistic regression analysis showed that age,NIHSS score,GCS score,APACHEⅡscore,blood glucose standard deviation,coefficient of variation of blood glucose were independent predictors of poor outcome in patients with severe acute stroke on 3 months after discharge.Conclusion Blood glucose variability are the independent predictors of poor outcome of the three months after discharge in patients with severe acute stroke,the great range of glycemic excursion indicates poor outcome.
基金supported by the National Basic Research Program of China under Grants 2010CB428603and2010CB950400100 Talents Program of the Chinese Academy of Sciences under Grant KZCX2-YW-BR-14
文摘<Abstract>This paper reports the seasonal feature of the relationship between ENSO and the stratospheric Polar Vortex Oscillation (PVO) variability in the Northern Hemisphere.It is shown that the lagged ENSO-PVO coupling relationship exhibits distinct seasonal feature,due to the strong seasonality of PVO and ENSO.Specifically,the PVO variability not only during winter,but also in autumn and spring months,is significantly correlated with ENSO anomalies leading by seasons;however,no significant effect of ENSO is found on the PVO variability in winter months of November and February.Although a significant ENSO effect is primarily observed when ENSO leads PVO by about one year,a significant correlation is also found between PVO in the following spring months (M +1 A +1) and ENSO anomalies in the previous autumn (A-1 S-1 O- 1 N -1) when ENSO anomalies lead by about 18 months.The significant correlation between PVO in various seasons and the corresponding ENSO anomalies leading by seasons could be explicitly verified in most of the individual years,confirming that the lagged ENSO effect can largely modulate the seasonal timescale variability of PVO.Moreover,the composite spatial patterns of the zonal-mean temperature anomalies further show that the ENSO effect on the PVO in various seasons is related to the interannual variability of the seasonal timescale PVO events.
文摘The somaclone, C39, derived by tissue culture from the obligate apomict Paspalum dilatatum cv Raki (2n=50), had 50 chromosomes and a karyotype apparently identical to Raki.SC2 seedlings of C39 showed a high degree of phenotypic variation which was of ten associated with increased chromosome numbers, but some of the variant seedlings were karyotypically indistinguishable from Raki or C39. Plants with increased chromosome numbers exhibited a high degree of intraplant chromosome variation (aneusomaty). In one of the SC2seedlings, the chromosome number of root tip cells varied from 58 to 82 and in several other seedlings the range was more than 10. The results suggested that the ability to form seed apomictically was much reduced in C39 and that this plant showed some capacity for sexual reproduction and the resulting seedlings, with a chromosome number of about 70, were genetically unstable. Of 11 SC2 seedlings examined cytolog ically, 6 did not produce any viable seed. Seedlings grown from seed of the remaining 5 plants showed that aneusomaty persisted in the SC3 generation. SC3 seedlings which were phenotypically similar to their maternal parent showed a similar range of chromosome numbers to that parent. Some of the SC3 seedlings exhibited an even wider range of chromosome numbers (e.g.56-136), and these plants were all dwarfs.
