Objective： To evaluate X-linked inhibitor of apoptosis protein （XIAP） expression in biopsy specimens from the patients with stage lib osteosarcomas before chemotherapy to study XIAP expression and its predictive si...Objective： To evaluate X-linked inhibitor of apoptosis protein （XIAP） expression in biopsy specimens from the patients with stage lib osteosarcomas before chemotherapy to study XIAP expression and its predictive significance of progosis in stage lib osteosarcomas. Methods： The expression of XIAP was retrospectively detected by SP immunohistochem- istry in 31 cases biopsy specimens from stage lib osteosarcomas before chemotherapy, and the relationship between XIAP expression and clinicopathologic features of the patients with stage lib osteosarcomas was analyzed. Results： The osteo- sarcoma specimens showed strong cell nucleus immunoreaction of XIAP while normal bone specimens showed weak. High XIAP positive expression independently predicted the patient＇s poor outcome and had no relationship with clinicopathologic variables such as age, gender, location, tumor size, rate of tumor necrosis to preoperative chemotherapy, local recurrence （P 〉 0.05）. Significant correlations were found between high XIAP expression and metastasis （P -- 0.022）, and also between high XIAP expression and final survival （P = 0.011）. Conclusion： XIAP plays an important role in the development of stage liB osteosarcomas and XIAP expression of biopsy specimens before chemotherapy can be seen as a promising prognostic marker in early predicting the outcome of patients suffering from stage lib osteosarcomas,展开更多
This paper presents a study of the effect of exposure to meanings of unknown vocabulary on reading comprehension in the target language (in this case, English). The subjects are 30 second-year Chinese college students...This paper presents a study of the effect of exposure to meanings of unknown vocabulary on reading comprehension in the target language (in this case, English). The subjects are 30 second-year Chinese college students. The results illustrate that the subjects' being exposed to the meanings of unknown words in a passage does exert a significant effect on their reading comprehension in the target language.展开更多
基金a grant from the Foundation for Scientific Research of Medical Science of Guangzhou (No. 2006-YB-017).
文摘Objective： To evaluate X-linked inhibitor of apoptosis protein （XIAP） expression in biopsy specimens from the patients with stage lib osteosarcomas before chemotherapy to study XIAP expression and its predictive significance of progosis in stage lib osteosarcomas. Methods： The expression of XIAP was retrospectively detected by SP immunohistochem- istry in 31 cases biopsy specimens from stage lib osteosarcomas before chemotherapy, and the relationship between XIAP expression and clinicopathologic features of the patients with stage lib osteosarcomas was analyzed. Results： The osteo- sarcoma specimens showed strong cell nucleus immunoreaction of XIAP while normal bone specimens showed weak. High XIAP positive expression independently predicted the patient＇s poor outcome and had no relationship with clinicopathologic variables such as age, gender, location, tumor size, rate of tumor necrosis to preoperative chemotherapy, local recurrence （P 〉 0.05）. Significant correlations were found between high XIAP expression and metastasis （P -- 0.022）, and also between high XIAP expression and final survival （P = 0.011）. Conclusion： XIAP plays an important role in the development of stage liB osteosarcomas and XIAP expression of biopsy specimens before chemotherapy can be seen as a promising prognostic marker in early predicting the outcome of patients suffering from stage lib osteosarcomas,
文摘This paper presents a study of the effect of exposure to meanings of unknown vocabulary on reading comprehension in the target language (in this case, English). The subjects are 30 second-year Chinese college students. The results illustrate that the subjects' being exposed to the meanings of unknown words in a passage does exert a significant effect on their reading comprehension in the target language.
