Background: Mental spatial transformations are ubiquitous and necessary for everyday spatial cognition, such as packing luggage into a car or repairing a broken vase. The posterior parietal cortex is known to be invol...Background: Mental spatial transformations are ubiquitous and necessary for everyday spatial cognition, such as packing luggage into a car or repairing a broken vase. The posterior parietal cortex is known to be involved in performing such transformations. Objective: To measure reorganization after lesioning of posterior parietal cortex areas subserving spatial transformation. Method: Brain activity in a patient who underwent a resection of right parietal cortex to manage intractable epilepsy was measured using fMRI while he performed a set of spatial transformation tasks. These data were compared with data from a group of healthy control subjects. Results: During spatial transformations, activity in the regions overlapping the resection was reduced in the patient compared with control subjects, but activity in the contralateral cortex was greater than that of control subjects. Conclusions: After a lesion the left hemisphere can adopt components of spatial reasoning normally subserved by the right hemisphere. This converges with evidence that components of language proces sing normally subserved by the left hemisphere can be taken over by the right hemisphere, suggesting that plasticity of function in the adult human cortex is a general characteristic.展开更多
运动功能障碍是急性脑梗死最常见的症状，特别是对手运动功能的影响最常见。但无论患者是否接受康复治疗，其运动功能都会不同程度的恢复，而这种自发性的功能恢复被归因于运动网络内的皮层功能重组，但其具体机制仍不清楚。运动网络主...运动功能障碍是急性脑梗死最常见的症状，特别是对手运动功能的影响最常见。但无论患者是否接受康复治疗，其运动功能都会不同程度的恢复，而这种自发性的功能恢复被归因于运动网络内的皮层功能重组，但其具体机制仍不清楚。运动网络主要包括双侧初级运动皮层（primary motor ayes，M1）、运动前区皮层（premotor cortex，PMC）和辅助运动（supplementary motorayca，SMA）。展开更多
文摘Background: Mental spatial transformations are ubiquitous and necessary for everyday spatial cognition, such as packing luggage into a car or repairing a broken vase. The posterior parietal cortex is known to be involved in performing such transformations. Objective: To measure reorganization after lesioning of posterior parietal cortex areas subserving spatial transformation. Method: Brain activity in a patient who underwent a resection of right parietal cortex to manage intractable epilepsy was measured using fMRI while he performed a set of spatial transformation tasks. These data were compared with data from a group of healthy control subjects. Results: During spatial transformations, activity in the regions overlapping the resection was reduced in the patient compared with control subjects, but activity in the contralateral cortex was greater than that of control subjects. Conclusions: After a lesion the left hemisphere can adopt components of spatial reasoning normally subserved by the right hemisphere. This converges with evidence that components of language proces sing normally subserved by the left hemisphere can be taken over by the right hemisphere, suggesting that plasticity of function in the adult human cortex is a general characteristic.
文摘运动功能障碍是急性脑梗死最常见的症状，特别是对手运动功能的影响最常见。但无论患者是否接受康复治疗，其运动功能都会不同程度的恢复，而这种自发性的功能恢复被归因于运动网络内的皮层功能重组，但其具体机制仍不清楚。运动网络主要包括双侧初级运动皮层（primary motor ayes，M1）、运动前区皮层（premotor cortex，PMC）和辅助运动（supplementary motorayca，SMA）。
