Phytochemical investigation of the leaves of Ilex aspralla (Hook. et Am.) Champ. ex Benth. led to the isolation of eleven compounds (1-11). By comparison with those reported data in the literatures their structure...Phytochemical investigation of the leaves of Ilex aspralla (Hook. et Am.) Champ. ex Benth. led to the isolation of eleven compounds (1-11). By comparison with those reported data in the literatures their structures were identified as kaempferol-3-O-β-D- 6"-acetylglucopyranoside (1), kaempferol-4'-methylether (2), quercetin (3), quercetin-3-O-glucopyranoside (4), tormentoside (5), suavissimoside R1 (6), 3β,19α-dihydroxyolean-12-ene-24,28-dioicacid-28-O-β-D-glucopyranoside (7), 3-O-β-sulfooxy-19-hydroxy- urs-12-ene-28-oic acid (8), coniferin (9), adenoside (10), 1'-O-benzyl-ct-L-rhamnopyranosyl-(l"→6')-β-D-glucopyranoside (11). Among these, six compounds (1, 2, 5, 9-11) were firstly reported from the genus Ilex, and five compounds (3, 4, 6-8) were isolated for the first time from llex aspralla.展开更多
基金National Key Technology R&D Program "New Drug Innovation" of China (Grant No.2012ZX09201-201-001,2012ZX09301002-002-002 and 2012ZX09304-005)Doctoral Fund of Ministry of Education (Grant No.20110001130003)
文摘Phytochemical investigation of the leaves of Ilex aspralla (Hook. et Am.) Champ. ex Benth. led to the isolation of eleven compounds (1-11). By comparison with those reported data in the literatures their structures were identified as kaempferol-3-O-β-D- 6"-acetylglucopyranoside (1), kaempferol-4'-methylether (2), quercetin (3), quercetin-3-O-glucopyranoside (4), tormentoside (5), suavissimoside R1 (6), 3β,19α-dihydroxyolean-12-ene-24,28-dioicacid-28-O-β-D-glucopyranoside (7), 3-O-β-sulfooxy-19-hydroxy- urs-12-ene-28-oic acid (8), coniferin (9), adenoside (10), 1'-O-benzyl-ct-L-rhamnopyranosyl-(l"→6')-β-D-glucopyranoside (11). Among these, six compounds (1, 2, 5, 9-11) were firstly reported from the genus Ilex, and five compounds (3, 4, 6-8) were isolated for the first time from llex aspralla.