A gold-catalyzed intermolecular reaction of ynamides with 3-indolyl azides via the presumable α-imino gold carbenes has been developed, providing an alternative and efficient way for the synthesis of valuable 3-amino...A gold-catalyzed intermolecular reaction of ynamides with 3-indolyl azides via the presumable α-imino gold carbenes has been developed, providing an alternative and efficient way for the synthesis of valuable 3-amino-β-carbolines in generally good to excellent yields. Importantly, this new protocol involves an unexpected 1,2-alkyl migration pathway.展开更多
基金supported by the National Natural Science Foundation of China (21622204 and 21572186)the Natural Science Foundation of Fujian Province for Distinguished Young Scholars (2015J06003)+1 种基金the President Research Funds from Xiamen University (20720150045)NFFTBS (J1310024)
文摘A gold-catalyzed intermolecular reaction of ynamides with 3-indolyl azides via the presumable α-imino gold carbenes has been developed, providing an alternative and efficient way for the synthesis of valuable 3-amino-β-carbolines in generally good to excellent yields. Importantly, this new protocol involves an unexpected 1,2-alkyl migration pathway.
