Objective: To investigate the diagnos- tic and therapeutic effect ofbronchofiberscopy in the manage- ment of severe thoracic trauma. Methods: A retrospective study was conducted on 207 consecutive patients with sev...Objective: To investigate the diagnos- tic and therapeutic effect ofbronchofiberscopy in the manage- ment of severe thoracic trauma. Methods: A retrospective study was conducted on 207 consecutive patients with severe thoracic trauma enrolled in our hospital between January 2008 and June 2012. During the period, 488 bronchofiberscopies and lavages were done. The bronchofiberscope was inserted through tracheal inci- sion (282), nasal cavity (149) and oral cavity (57). Intensive SaO2 monitoring as well as blood gas analysis were per- formed pre-, intra- and postoperatively. Simultaneously oxy- gen therapy or ventilatory support was given. Sputum cul- ture was done intraoperatively. Results: Diagnosis in 207 cases was confirmed by bronchofiberscopy. The result of sputum culture was posi- tive in 78 cases. Lavage was performed on 156 cases. SaO2 significantly increased after bronchofiberscopies as well as lavages and PaO2 obviously improved 2 h after surgery (both P〈0.05). Heart rate and respiratory rate decreased. There was no bronchofiberscopy-related death. Conclusion: Bronchofiberscopy plays an important role in the diagnosis and treatment of severe thoracic trauma, which can not only timely diagnose bronchial injury and collect deep tracheal sputum for bacterial culture but also effectively remove foreign body, secretion, blood and spu- tum crust in the airway, manage obstructive atelectasis and pneumonia, and signifcantly improve respiratory fimction and treatment outcome.展开更多
In order to examine the chemical form of uranyl species in l-ethyl-3-methylimidazolium (EMI) based ionic liquids, UV-visible absorption spectra of solutions prepared by dissolving [EMI]2[UO2CI4] into a mixture of EM...In order to examine the chemical form of uranyl species in l-ethyl-3-methylimidazolium (EMI) based ionic liquids, UV-visible absorption spectra of solutions prepared by dissolving [EMI]2[UO2CI4] into a mixture of EMICI and EMIBF4 (50:50 tool%) were measured. As a result, it was confirmed that uranyl species in the mixture of EMICI and EMIBF4 existed as [UO2C14]2-. Cyclic voltammograms (CVs) of [UO2CI4]2- in the mixture were measured at 25 ~C using a Pt working electrode, a Pt wire counter electrode, and an Ag/Ag+ reference electrode (0.01 M AgNO3, 0.1 M tetrabutylammonium perchlorate in acetonitrile) in a glove box under an Ar atmosphere. Peaks corresponding to one redox couple were observed around -1.05 V (Epc) and -0.92 V (Epa) vs. ferrocene/ferrocenium ion (Fc/Fc+). The potential differences between two peaks (AEp) increased from 101 to 152 mV with an increase in the scan rate from 50 to 300 mV s-1, while the (Epc + Epa)/2 value was constant, -0.989 V vs. Fc/Fc+ regardless of the scan rate. Furthermore, the diffusion coefficient of [UO2C14]2 and the standard rate constant were es- timated to be 3.7× 10^-8 cm^2 s 1 and (2.7-2,8) × 10^-4 cm s-! at 25 ℃. By using the diffusion coefficient and the standard rate constant, the simulation of CVs was performed based on the reaction, [UO2C14]2- + e- = [UO2C14]3-. The simulated CVs were found to be consistent with the experimental ones. From these results, it is concluded that [UO2C14]2- in the mixture of EMIC1 and EMIBF4 is reduced to [UO2C14]3- quasi-reversibly at -0.989 V vs. Fc/Fc+.展开更多
文摘Objective: To investigate the diagnos- tic and therapeutic effect ofbronchofiberscopy in the manage- ment of severe thoracic trauma. Methods: A retrospective study was conducted on 207 consecutive patients with severe thoracic trauma enrolled in our hospital between January 2008 and June 2012. During the period, 488 bronchofiberscopies and lavages were done. The bronchofiberscope was inserted through tracheal inci- sion (282), nasal cavity (149) and oral cavity (57). Intensive SaO2 monitoring as well as blood gas analysis were per- formed pre-, intra- and postoperatively. Simultaneously oxy- gen therapy or ventilatory support was given. Sputum cul- ture was done intraoperatively. Results: Diagnosis in 207 cases was confirmed by bronchofiberscopy. The result of sputum culture was posi- tive in 78 cases. Lavage was performed on 156 cases. SaO2 significantly increased after bronchofiberscopies as well as lavages and PaO2 obviously improved 2 h after surgery (both P〈0.05). Heart rate and respiratory rate decreased. There was no bronchofiberscopy-related death. Conclusion: Bronchofiberscopy plays an important role in the diagnosis and treatment of severe thoracic trauma, which can not only timely diagnose bronchial injury and collect deep tracheal sputum for bacterial culture but also effectively remove foreign body, secretion, blood and spu- tum crust in the airway, manage obstructive atelectasis and pneumonia, and signifcantly improve respiratory fimction and treatment outcome.
文摘In order to examine the chemical form of uranyl species in l-ethyl-3-methylimidazolium (EMI) based ionic liquids, UV-visible absorption spectra of solutions prepared by dissolving [EMI]2[UO2CI4] into a mixture of EMICI and EMIBF4 (50:50 tool%) were measured. As a result, it was confirmed that uranyl species in the mixture of EMICI and EMIBF4 existed as [UO2C14]2-. Cyclic voltammograms (CVs) of [UO2CI4]2- in the mixture were measured at 25 ~C using a Pt working electrode, a Pt wire counter electrode, and an Ag/Ag+ reference electrode (0.01 M AgNO3, 0.1 M tetrabutylammonium perchlorate in acetonitrile) in a glove box under an Ar atmosphere. Peaks corresponding to one redox couple were observed around -1.05 V (Epc) and -0.92 V (Epa) vs. ferrocene/ferrocenium ion (Fc/Fc+). The potential differences between two peaks (AEp) increased from 101 to 152 mV with an increase in the scan rate from 50 to 300 mV s-1, while the (Epc + Epa)/2 value was constant, -0.989 V vs. Fc/Fc+ regardless of the scan rate. Furthermore, the diffusion coefficient of [UO2C14]2 and the standard rate constant were es- timated to be 3.7× 10^-8 cm^2 s 1 and (2.7-2,8) × 10^-4 cm s-! at 25 ℃. By using the diffusion coefficient and the standard rate constant, the simulation of CVs was performed based on the reaction, [UO2C14]2- + e- = [UO2C14]3-. The simulated CVs were found to be consistent with the experimental ones. From these results, it is concluded that [UO2C14]2- in the mixture of EMIC1 and EMIBF4 is reduced to [UO2C14]3- quasi-reversibly at -0.989 V vs. Fc/Fc+.