In this paper, applying the dependent and independent variables transformations as well as the Jacobi elliptic function expansion method, the envelope periodic solutions to one-dimensional Gross-Pitaevskii equation in...In this paper, applying the dependent and independent variables transformations as well as the Jacobi elliptic function expansion method, the envelope periodic solutions to one-dimensional Gross-Pitaevskii equation in Bose-Einstein condensates are obtained.展开更多
[Objective] This study aimed to research the effect of metallothionein on cell cycle, apoptosis rate and subsets distribution of lymphocytes in peripheral blood of dairy cows under heat stress, so as to perfect the re...[Objective] This study aimed to research the effect of metallothionein on cell cycle, apoptosis rate and subsets distribution of lymphocytes in peripheral blood of dairy cows under heat stress, so as to perfect the regulative mechanism re- searches of MT to anti-heat stress. [Method] Twenty lactating Chinese Holstein cows were randomly divided into four groups （A, B, C and D）, and injected with 0, 4.0, 8.0 and 12.0 mg Zn-metallothionein, respectively by intravenous route. Blood sam- ples were collected at 1＂, 16~, 31~, 46~ and 61~ day, and the dynamic changes of cell cycle, apoptosis rate and subsets distribution of lymphocytes were determined. [Result] The apoptosis rate of cells in group B and C was lower than those in group A by 26.63% （P〉0.05） and 24.84% （P〉0.05） respectively. The number of cells in the Gc/G1 phage in trial groups was increased and the number of cells in the S and GJM phages tended to decrease, but there were no significant differences （P〉 0.05）. The number of CD3~ T cell in three trial groups was greater than those in group A by 7.02% （P〉0.05）, 5.45% （P〉0.05） and 3.85% （P〉0.05） respectively, while the number of CD4~ T cell in trial groups was higher than those in control group by 31.04% （P〈0.05）, 35.68% （P〈0.05） and 39.34% （P〈0.05） respectively. The number of CD8＇ T cell and the levels of CD4＊/CD8~ in trial groups were increased observ- ably, but significant difference （P〈0.05） was observed in the levels of CD4~/CD8~ between groups A and C only. It demonstrated that exogenous Zn-metallothionein can decrease apoptosis rate, improve cell cycle and regulate subsets distribution of lymphocytes in dairy cattle in a dose-dependent manner. [Conclusion] This study will provide scientific basis for safe utilization of MT in dairy industry.展开更多
The aim of this study is to further understand the genotype of Hantavirus （HV） from peripheral blood of patients with hemorrhagic fever with renal syndrome （HFRS） and the epidemiological significance of this disea...The aim of this study is to further understand the genotype of Hantavirus （HV） from peripheral blood of patients with hemorrhagic fever with renal syndrome （HFRS） and the epidemiological significance of this disease in Heilongjiang province in recent years. Thirty-one serum samples of clinically diagnosed patients with HFRS were examined by RT-PCR to decide the genetic subtype. On the basis of infection season, the serum samples were divided into two groups： winter （Nov, 2003--Feb, 2004）, spring and summer （April, 200d--Sep, 2004）. Further analysis was performed in combination with clinical symptoms. It was found that among the total 31 samples, 22 were sero-positive. Among 14 serum samples in winter, 8 were sero-positive, of which 5 cases were of type Ⅰ （Hantaan virus, HTNV） and 3 of type Ⅱ （Seoul virus, SEOV）. Among 17 samples in spring and summer, 14 were sero-positive, of which 5 cases were of type Ⅰ and 9 of type Ⅱ . So it concludes that both of the two types of Hantavirus exist in Heilongjiang. The type Ⅰ is the main pathogen of HFRS in winter, and typeⅡ is the main in spring and summer.展开更多
An incipient stage of a rotating drill string bit whirl motion proceeding on a well bottom surface is studied on the basis of kinematic （nonholonomic） models of mechanic interaction between the contacting uneven bod...An incipient stage of a rotating drill string bit whirl motion proceeding on a well bottom surface is studied on the basis of kinematic （nonholonomic） models of mechanic interaction between the contacting uneven bodies. The bit is considered to be an absolutely rigid spherical or ellipsoidal body, the well bottom surface can be plane or spherical. It is assumed that the system coaxiality is disturbed through small initial curvature of the drill string, imperfections of the bit and bore-well geometry or the system mass debalance. Linearized equations of the bit whirling are deducted, the frequencies of periodic motions are calculated, and their modes are constructed for different geometric parameters of the spherical and ellipsoidal bits. It is demonstrated that, depending on the system properties, the bit motion can acquire the regimes of forward and backward whMings or to transit to the state of stationary spinning relative to an immovable center of velocities. The most unfavorable and atypical whirling modes are characteristic for oblate eilipsoidal bits and curvilinear surfaces of the well bottom.展开更多
The authors examined 184 residents from Kazakhstan to reveal an association of the CCND1 gene A870G and TP53 gene Arg72Pro polymorphisms with esophageal cancer risk. 86 of them were control group and 98 were patients ...The authors examined 184 residents from Kazakhstan to reveal an association of the CCND1 gene A870G and TP53 gene Arg72Pro polymorphisms with esophageal cancer risk. 86 of them were control group and 98 were patients with esophageal cancer. DNA samples were genotyped by direct sequencing method and TaqMan allelic discrimination method. Statistical analysis was performed using GraphPad InStatTM Software and ＂Case-Control Study Estimating Calculator＂ from TAPOTILI company. A significant association was revealed between CCND1 homozygous genotype （A870A, OR=2.654） and TP53 heterozygous （Arg72Pro, OR= 1.417） and homozygous （Pro72 Pro, OR=2.860） genotypes increased risk of esophageal cancer.展开更多
In order to elucidate the molecular and immunological mechanisms as well as the pathogenesis of hemorrhagic fever with renal syndrome (HFRS), the CD8 + cytotoxic T lymphocytes (CTL) clone was established directly from...In order to elucidate the molecular and immunological mechanisms as well as the pathogenesis of hemorrhagic fever with renal syndrome (HFRS), the CD8 + cytotoxic T lymphocytes (CTL) clone was established directly from peripheral blood mononuclear cells (PBMC) of patients with HFRS. The activities of CTL were detected as usual with EBV-transformed lymphoblastoid cell line (BLCL) as target cells. The results showed that the CTL clone could recognized and killed the target cells with specificity of nucleocapsid protein of Hantaan virus (HTNVNP) with the cytotoxicity percentages of 50.2%, 25.4% and 39.0% respectively. These results demonstrated that the antigenic epitopes of HTNVNP mainly located on the C-terminal of the viral nucleocapsid protein.展开更多
A computer analysis of solar heating has been performed for Palestine. Results are presented for a prototype building using either fuel oil or gas under different heating loads in three climatic regions （Jordan valle...A computer analysis of solar heating has been performed for Palestine. Results are presented for a prototype building using either fuel oil or gas under different heating loads in three climatic regions （Jordan valley, coastal, and hilly）. Cumulative cost flows are compared for the life-cycle present value technique. Optimum design magnitudes are determined for maximum life-cycle savings. The payback period for capital invested in a solar system, and total savings are found for the optimum conditions. Variations of system performance are estimated. The effects of collector slope, proportionate storage tank volume, heat-exchanger parameters, and the design load on system performance are studied. Finally the economics of solar heating in Palestine are discussed and recommendations are made for increased utilization of solar energy.展开更多
In this paper we construct a new time-periodic solution of the vacuum Einstein's field equations, this solution possesses physical singularities, i.e., the norm of the solution's Riemann curvature tensor takes...In this paper we construct a new time-periodic solution of the vacuum Einstein's field equations, this solution possesses physical singularities, i.e., the norm of the solution's Riemann curvature tensor takes the infinity at some points. We show that this solution is intrinsically time-periodic and describes a time-periodic universe with the "time-periodic physical singularity". By calculating the Weyl scalars of this solution, we investigate new physical phenomena and analyze new singularities for this universal model.展开更多
基金Supported by National Natural Science Foundation of China under Grant No. 90511009
文摘In this paper, applying the dependent and independent variables transformations as well as the Jacobi elliptic function expansion method, the envelope periodic solutions to one-dimensional Gross-Pitaevskii equation in Bose-Einstein condensates are obtained.
基金Supported by grants from the National Science Foundation of China(31072053,30671516)Natural Science Foundation of Hunan Province,China(11JJ2014)Specialized Research Fund for the Doctoral Program of Higher Education,Ministry of Education,China(20104320110001)
文摘[Objective] This study aimed to research the effect of metallothionein on cell cycle, apoptosis rate and subsets distribution of lymphocytes in peripheral blood of dairy cows under heat stress, so as to perfect the regulative mechanism re- searches of MT to anti-heat stress. [Method] Twenty lactating Chinese Holstein cows were randomly divided into four groups （A, B, C and D）, and injected with 0, 4.0, 8.0 and 12.0 mg Zn-metallothionein, respectively by intravenous route. Blood sam- ples were collected at 1＂, 16~, 31~, 46~ and 61~ day, and the dynamic changes of cell cycle, apoptosis rate and subsets distribution of lymphocytes were determined. [Result] The apoptosis rate of cells in group B and C was lower than those in group A by 26.63% （P〉0.05） and 24.84% （P〉0.05） respectively. The number of cells in the Gc/G1 phage in trial groups was increased and the number of cells in the S and GJM phages tended to decrease, but there were no significant differences （P〉 0.05）. The number of CD3~ T cell in three trial groups was greater than those in group A by 7.02% （P〉0.05）, 5.45% （P〉0.05） and 3.85% （P〉0.05） respectively, while the number of CD4~ T cell in trial groups was higher than those in control group by 31.04% （P〈0.05）, 35.68% （P〈0.05） and 39.34% （P〈0.05） respectively. The number of CD8＇ T cell and the levels of CD4＊/CD8~ in trial groups were increased observ- ably, but significant difference （P〈0.05） was observed in the levels of CD4~/CD8~ between groups A and C only. It demonstrated that exogenous Zn-metallothionein can decrease apoptosis rate, improve cell cycle and regulate subsets distribution of lymphocytes in dairy cattle in a dose-dependent manner. [Conclusion] This study will provide scientific basis for safe utilization of MT in dairy industry.
文摘The aim of this study is to further understand the genotype of Hantavirus （HV） from peripheral blood of patients with hemorrhagic fever with renal syndrome （HFRS） and the epidemiological significance of this disease in Heilongjiang province in recent years. Thirty-one serum samples of clinically diagnosed patients with HFRS were examined by RT-PCR to decide the genetic subtype. On the basis of infection season, the serum samples were divided into two groups： winter （Nov, 2003--Feb, 2004）, spring and summer （April, 200d--Sep, 2004）. Further analysis was performed in combination with clinical symptoms. It was found that among the total 31 samples, 22 were sero-positive. Among 14 serum samples in winter, 8 were sero-positive, of which 5 cases were of type Ⅰ （Hantaan virus, HTNV） and 3 of type Ⅱ （Seoul virus, SEOV）. Among 17 samples in spring and summer, 14 were sero-positive, of which 5 cases were of type Ⅰ and 9 of type Ⅱ . So it concludes that both of the two types of Hantavirus exist in Heilongjiang. The type Ⅰ is the main pathogen of HFRS in winter, and typeⅡ is the main in spring and summer.
文摘An incipient stage of a rotating drill string bit whirl motion proceeding on a well bottom surface is studied on the basis of kinematic （nonholonomic） models of mechanic interaction between the contacting uneven bodies. The bit is considered to be an absolutely rigid spherical or ellipsoidal body, the well bottom surface can be plane or spherical. It is assumed that the system coaxiality is disturbed through small initial curvature of the drill string, imperfections of the bit and bore-well geometry or the system mass debalance. Linearized equations of the bit whirling are deducted, the frequencies of periodic motions are calculated, and their modes are constructed for different geometric parameters of the spherical and ellipsoidal bits. It is demonstrated that, depending on the system properties, the bit motion can acquire the regimes of forward and backward whMings or to transit to the state of stationary spinning relative to an immovable center of velocities. The most unfavorable and atypical whirling modes are characteristic for oblate eilipsoidal bits and curvilinear surfaces of the well bottom.
文摘The authors examined 184 residents from Kazakhstan to reveal an association of the CCND1 gene A870G and TP53 gene Arg72Pro polymorphisms with esophageal cancer risk. 86 of them were control group and 98 were patients with esophageal cancer. DNA samples were genotyped by direct sequencing method and TaqMan allelic discrimination method. Statistical analysis was performed using GraphPad InStatTM Software and ＂Case-Control Study Estimating Calculator＂ from TAPOTILI company. A significant association was revealed between CCND1 homozygous genotype （A870A, OR=2.654） and TP53 heterozygous （Arg72Pro, OR= 1.417） and homozygous （Pro72 Pro, OR=2.860） genotypes increased risk of esophageal cancer.
文摘In order to elucidate the molecular and immunological mechanisms as well as the pathogenesis of hemorrhagic fever with renal syndrome (HFRS), the CD8 + cytotoxic T lymphocytes (CTL) clone was established directly from peripheral blood mononuclear cells (PBMC) of patients with HFRS. The activities of CTL were detected as usual with EBV-transformed lymphoblastoid cell line (BLCL) as target cells. The results showed that the CTL clone could recognized and killed the target cells with specificity of nucleocapsid protein of Hantaan virus (HTNVNP) with the cytotoxicity percentages of 50.2%, 25.4% and 39.0% respectively. These results demonstrated that the antigenic epitopes of HTNVNP mainly located on the C-terminal of the viral nucleocapsid protein.
文摘A computer analysis of solar heating has been performed for Palestine. Results are presented for a prototype building using either fuel oil or gas under different heating loads in three climatic regions （Jordan valley, coastal, and hilly）. Cumulative cost flows are compared for the life-cycle present value technique. Optimum design magnitudes are determined for maximum life-cycle savings. The payback period for capital invested in a solar system, and total savings are found for the optimum conditions. Variations of system performance are estimated. The effects of collector slope, proportionate storage tank volume, heat-exchanger parameters, and the design load on system performance are studied. Finally the economics of solar heating in Palestine are discussed and recommendations are made for increased utilization of solar energy.
基金supported by National Natural Science Foundation of China (Grant No.10971190) and the Qiu-Shi Professor Fellowship from Zhejiang University,China
文摘In this paper we construct a new time-periodic solution of the vacuum Einstein's field equations, this solution possesses physical singularities, i.e., the norm of the solution's Riemann curvature tensor takes the infinity at some points. We show that this solution is intrinsically time-periodic and describes a time-periodic universe with the "time-periodic physical singularity". By calculating the Weyl scalars of this solution, we investigate new physical phenomena and analyze new singularities for this universal model.
