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细胞周期调节因子在原发和复发鼻咽癌的表达 被引量:4
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作者 李锦添 黄平 +2 位作者 肖永波 周昕熙 陈诗萍 《中山医科大学学报》 CSCD 北大核心 2001年第3期184-186,237,共4页
【目的】探讨细胞周期调节因子在鼻咽癌复发中的作用。【方法】采用LsAB法同时检测 6 9例患者原发和复发鼻咽癌组织中p5 3、MDM2 、p2 1ras和p2 1WAF1蛋白的表达。【结果】复发癌与原发癌相比 :阳性表达率方面 ,p5 3蛋白 (78%和80 % )或... 【目的】探讨细胞周期调节因子在鼻咽癌复发中的作用。【方法】采用LsAB法同时检测 6 9例患者原发和复发鼻咽癌组织中p5 3、MDM2 、p2 1ras和p2 1WAF1蛋白的表达。【结果】复发癌与原发癌相比 :阳性表达率方面 ,p5 3蛋白 (78%和80 % )或MDM2 蛋白 (84%和 83% )很相近 ,p2 1ras蛋白 (73%和 93% )或p2 1WAF1蛋白 (5 2 %和 84% )明显下降 ;高表达率方面 ,p5 3蛋白 (4 2 %和 5 1% )很相近 ,MDM2 蛋白 (5 7%和 32 % )明显升高 ,p2 1ras蛋白 (16 %和 6 5 % )或 p2 1WAF1蛋白 (17%和 46 % )明显下降。其中 ,MDM2 蛋白表达水平在复发癌明显升高主要见于复发间期 <34个月患者组 (P <0 0 5 ) ,p2 1ras蛋白和 p2 1WAF1蛋白表达水平在复发癌明显下降见于复发间期 <34个月和≥ 34个月患者组 (均 <0 0 2以下 )。【结论】原发鼻咽癌临床治愈后 ,p5 3蛋白和MDM2 蛋白过度表达以及 p2 1WAF1蛋白低表达或不表达可能仍然对鼻咽癌的复发起重要作用 ;MDM2 蛋白表达水平显著升高和p2 展开更多
关键词 鼻咽癌 细胞周期因子 P53 MDM2蛋白 P21 癌基因蛋白
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自然数数码和的m次方映射数列的周期性
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作者 冯国平 雍青康 《天水师范学院学报》 2004年第2期3-5,共3页
证明了自然数数码和的m次方映射数列{nk}为周期数列,给出了当m=2,3,4,5,6时,{nk}的周期节及对任意自然数n,必存在自然数k0,当k≥k0时,Tk(n)进入相应周期节的条件。
关键词 自然数 数码和 m次方映射数列 周期数列 周期节
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美国:RGGI带动能源节约投资20亿美元
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《节能与环保》 2014年第4期14-14,共1页
日前,美国区域温室气体减排行动组织(以下简称RGGI)向外发布了一份名为《2012年区域温室气体行动C02配额收入的区域投资》的报告,声称在该机制下拍卖C02排放量所得的约7亿美元将实现全生命周期节约能源费用超过近20亿美元的可观回报。
关键词 约投资 能源费用 美国 温室气体减排 C02 周期节 排放量
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探讨两个映射数列问题
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作者 吴文权 《阿坝师范高等专科学校学报》 1999年第1期68-70,共3页
本文给出了自然数数码方幂问题周期性的存在定理,进而对2次方和3次方的情形给出了具体的解答;本文还对二进制下的黑洞数问题进行了全面的讨论,得到了二进制下的所有黑洞数,黑洞长度和黑程。
关键词 映射数列 周期节 黑洞数 黑程 二进制 自然数 数码 初等数学
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Thermal Induced Periodic Phase Separation in Polymer Blends
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作者 孙喆 宋海华 《Chinese Journal of Chemical Physics》 SCIE CAS CSCD 北大核心 2006年第2期99-101,共3页
Simulations were carried out for studying the periodic phase separation of a symmetric binary polymer blend on the basis of Cahn-Hilliard-Cook theory. The time dependent interaction parameter x(τ) was assumed to un... Simulations were carried out for studying the periodic phase separation of a symmetric binary polymer blend on the basis of Cahn-Hilliard-Cook theory. The time dependent interaction parameter x(τ) was assumed to undergo a step-wise oscillation. The hierarchic structures composed of both large and small domains were obtained. The mechanism of the periodic formation of hierarchic structures was also demonstrated. 展开更多
关键词 Periodic spinodal decomposition Simulations Hierarchic structures
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基于CAE技术的车身用胶选择方法 被引量:1
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作者 陈平 王锴 +1 位作者 余乐铭 胡永明 《重型汽车》 2014年第3期32-33,共2页
结合现有车身用胶产生的品质故障,通过CAE分析技术,建立相应分析计算模型,提出基于CAE技术的车身用胶选择方法,并应用于实际改进,取得了良好的效果,保证车身用胶选择的合理性同时缩短周期节省成本。
关键词 CAE技术 车身 CAE分析 计算模型 周期节
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Analysis and Modeling of the Central Air-Conditioning System in Intelligent Buildings 被引量:6
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作者 郭巧 徐庆伟 《Journal of Beijing Institute of Technology》 EI CAS 2002年第3期295-297,共3页
The central air conditioning system in an intelligent building (IB) was analyzed and modeled in order to perform the optimization scheduling strategy of the central air conditioning system. A set of models proposed ... The central air conditioning system in an intelligent building (IB) was analyzed and modeled in order to perform the optimization scheduling strategy of the central air conditioning system. A set of models proposed and a type of periodically autoregressive model (PAR) based on the improved genetic algorithms (IGA) were used to perform the optimum energy saving scheduling. The example of the Liangmahe Plaza was taken to show the effectiveness of the methods. 展开更多
关键词 intelligent building analysis and modeling central air conditioning energy saving
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Regulation of the G1 phase of the mammalian cell cycle 被引量:18
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作者 DONJERKOVIC DUBRRAVKA DAVID W SCOTT (Department of Immunology, Holland Laboratory for the Biomedical Sciences, American Red Cross, 15601 Crabbs Branch Way, Rockville, MD) 《Cell Research》 SCIE CAS CSCD 2000年第1期1-16,共16页
In any multi-cellular organism, the balance between cell division and cell death maintains a constant cell number. Both cell division cycle and cell death are highly regulated events. Whether the cell will proceed thr... In any multi-cellular organism, the balance between cell division and cell death maintains a constant cell number. Both cell division cycle and cell death are highly regulated events. Whether the cell will proceed through the cycle or not, depends upon whether the conditions required at the checkpoints during the cycle are fulfilled. In higher eucaryotic cells, such as mammalian cells, signals that arrest the cycle usually act at a G1 checkpoint. Cells that pass this restriction point are committed to complete the cycle. Regulation of the GI phase of the cell cycle is extremely complex and involves many different families of proteins such as retinoblastoma family cyclin dependent kinases, cyclins, and cyclic kinase inhibitors. 展开更多
关键词 Cell cycle cyclin dependent kinase CYCLIN cyclin kinase inhibitor.
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DELETIONS AND POINT MUTATIONS OF p16,p15 GENE IN PRIMARY TUMORS AND TUMOR CELL LINES 被引量:2
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作者 陶勇浩 黄倩 +1 位作者 李川源 DavidW.Yandell 《Chinese Medical Sciences Journal》 CAS CSCD 1999年第4期200-205,共6页
Aberrations of chromosome 9 p21 22 are involved in the genesis of many forms of cancer.The gene p16 and p15 have been assigned to this region.Both p16 and p15 are an inhibitor of cycli... Aberrations of chromosome 9 p21 22 are involved in the genesis of many forms of cancer.The gene p16 and p15 have been assigned to this region.Both p16 and p15 are an inhibitor of cyclin D cdk4,cyclin D cdk6 complex and have been implicated in a wide variety of cancer types,including the germline of patients with familial melanoma.In order to investigate and compare the status of p16,p15 gene in primary tumors and cell lines,we examined 357 primary tumors and 29 cell lines derived from diverse tumor types.In addition to analysis of these primary tumors and cell lines,blood specimens from 91 patients either with sporadic multiple cancers or from cancer prone families were also analyzed.The data showed the following:1)Homozygous deletions of p16,p15 were comparatively rare and far less common than previously reported,although hemizygous deletions were observed in a significant fraction of many tumor types;2)the incidence of p16,p15 deletions(either homozygous deletions or heterozygous deletions)varied significantly among different tumor types;3)most deletions involved in both p16 and p15 genes;4)sequence variations in the coding sequence of p16,p15 were comparatively rare among these tumor types,though mutations and polymorphisms were identified;5)some tumors which showed LOH at 9p,containing p16 and p15 gene,did not show deletions or point mutations in the p16,p15 gene.6)In a subset of retinoblastoma and osteosarcoma where no Rb gene mutations were present a significant fraction was found to contain p16,p15 gene deletions. 展开更多
关键词 p16 gene p15 gene DELETION point mutation
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Effect of Metallothionein on Cell Cycle,Apoptosis Rate and Subsets Distribution of Lymphocytes in Peripheral Blood of Dairy Cattle under Heat Stress 被引量:1
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作者 Jiajie LUO Lili LI +7 位作者 Bin ZHANG LiZhuan WU Zijun LI Ying PENG JueXin FAN XinYi LAN JinShun ZHAN Jun FANG 《Agricultural Science & Technology》 CAS 2013年第10期1457-1461,共5页
[Objective] This study aimed to research the effect of metallothionein on cell cycle, apoptosis rate and subsets distribution of lymphocytes in peripheral blood of dairy cows under heat stress, so as to perfect the re... [Objective] This study aimed to research the effect of metallothionein on cell cycle, apoptosis rate and subsets distribution of lymphocytes in peripheral blood of dairy cows under heat stress, so as to perfect the regulative mechanism re- searches of MT to anti-heat stress. [Method] Twenty lactating Chinese Holstein cows were randomly divided into four groups (A, B, C and D), and injected with 0, 4.0, 8.0 and 12.0 mg Zn-metallothionein, respectively by intravenous route. Blood sam- ples were collected at 1", 16~, 31~, 46~ and 61~ day, and the dynamic changes of cell cycle, apoptosis rate and subsets distribution of lymphocytes were determined. [Result] The apoptosis rate of cells in group B and C was lower than those in group A by 26.63% (P〉0.05) and 24.84% (P〉0.05) respectively. The number of cells in the Gc/G1 phage in trial groups was increased and the number of cells in the S and GJM phages tended to decrease, but there were no significant differences (P〉 0.05). The number of CD3~ T cell in three trial groups was greater than those in group A by 7.02% (P〉0.05), 5.45% (P〉0.05) and 3.85% (P〉0.05) respectively, while the number of CD4~ T cell in trial groups was higher than those in control group by 31.04% (P〈0.05), 35.68% (P〈0.05) and 39.34% (P〈0.05) respectively. The number of CD8' T cell and the levels of CD4*/CD8~ in trial groups were increased observ- ably, but significant difference (P〈0.05) was observed in the levels of CD4~/CD8~ between groups A and C only. It demonstrated that exogenous Zn-metallothionein can decrease apoptosis rate, improve cell cycle and regulate subsets distribution of lymphocytes in dairy cattle in a dose-dependent manner. [Conclusion] This study will provide scientific basis for safe utilization of MT in dairy industry. 展开更多
关键词 Exogenous metallothionein Heat stress Immunity Dynamic change Chinese Holstein cows
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Seasonal Variation of Biochemical Components in Clam (Saxidomuspurpuratus Sowerby 1852) in Relation to Its Reproductive Cycle and the Environmental Condition of Sanggou Bay, China 被引量:7
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作者 BI Jinhong LI Qi +4 位作者 ZHANG Xinjun ZHANG Zhixin TIAN Jinling XU Yushan LIU Wenguang 《Journal of Ocean University of China》 SCIE CAS 2016年第2期341-350,共10页
Seasonal variation of biochemical components in clam(Saxidomus purpuratus Sowerby 1852) was investigated from March 2012 to February 2013 in relation to environmental condition of Sanggou Bay and the reproductive cycl... Seasonal variation of biochemical components in clam(Saxidomus purpuratus Sowerby 1852) was investigated from March 2012 to February 2013 in relation to environmental condition of Sanggou Bay and the reproductive cycle of clam.According to the histological analysis,the reproductive cycle of S.purpuratus includes two distinctive phases:a total spent and inactive stage from November to January,and a gametogenesis stage,including ripeness and spawning,during the rest of the year.Gametes were generated at a low temperature(2.1℃) in February.Spawning took place once a year from June to October.The massive spawning occurred in August when the highest water temperature and chlorophyll a level could be observed.The key biochemical components(glycogen,protein and lipid) in five tissues(gonad,foot,mantle,siphon and adductor muscle) were analyzed.The glycogen content was high before gametogenesis,and decreased significantly during the gonad development in the gonad,mantle and foot of both females and males,suggesting that glycogen was an important energy source for gonad development.The protein and lipid contents increased in the ovary during the gonad development,demonstrating that they are the major organic components of oocytes.The lipid and protein contents decreased in the testis,implying that they can provide energy and material for spermatogenesis.The results also showed that protein stored in the mantle and foot could support the reproduction after the glycogen was depleted. 展开更多
关键词 Saxidomus purpuratus GAMETOGENESIS biochemical composition environmental factor
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Seasonal Changes of Reproductive Activity and Biochemical Composition of Pen Shell Atrina pectinata Linnaeus,1767 in Bohai Sea,China 被引量:2
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作者 WANG Changbo LI Qi +1 位作者 XU Chengxun YU Ruihai 《Journal of Ocean University of China》 SCIE CAS CSCD 2017年第3期479-489,共11页
Seasonal variations in the biochemical composition and the reproductive cycle of pen shell Atrina pectinata in Bohai Sea were investigated from May 2013 to April 2014. Histological analysis indicated that the reproduc... Seasonal variations in the biochemical composition and the reproductive cycle of pen shell Atrina pectinata in Bohai Sea were investigated from May 2013 to April 2014. Histological analysis indicated that the reproductive cycle of A. pectinata can be divided into two phases, inactive stage and gametogenesis, which were equally and significantly influenced by seawater temperature and food availability. Gametogenesis began in late autumn(October), and completed in June and July. Spawning took place in August, coinciding with the highest water temperature and the richest phytoplankton. The significantly high glycogen content in adductor muscles sustained throughout the late active and ripeness stages, but plummeted during spawning and inactive stages. The protein content in female gonads exhibited a synchronous increase along with oocyte diameter and lipid content, suggesting that the female gonads could accumulate protein and lipid for vitelline in A. pectinata. Furthermore, the RNA/DNA ratio was found to be a useful index to indicate the level of gonad maturation in both males and females. The findings of the present study provided a foundation for the fishery resource administration and the aquaculture development of this species. 展开更多
关键词 biochemical composition reproductive cycle environment factor Atrina pectinata seasonal variation
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Effect of androgen withdrawal on activation of ERKs and expression of cell cycle regulation molecules in human prostate carcinoma cells
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作者 叶定伟 李慧 +5 位作者 TSENG Jane CHAUVIN Priscilla 钱松溪 郑家富 孙颖浩 马永江 《Journal of Medical Colleges of PLA(China)》 CAS 2002年第3期178-180,共3页
Objective: To explore the possible mechanisms of growth regression of human androgen dependent prostate carcinoma cells caused by androgen withdrawal. Methods: After 24 h of treatment with 1 × 10-9 mol/L dihydrot... Objective: To explore the possible mechanisms of growth regression of human androgen dependent prostate carcinoma cells caused by androgen withdrawal. Methods: After 24 h of treatment with 1 × 10-9 mol/L dihydrotestosterone (DHT), the expression of phosphorylated ERK proteins and cell cycle regulation molecules including CDK2, CDK4, CDK6 and P27kip1 in human androgen dependent prostate carcinoma cell line LNCaP was measured by Western blot analysis 0 h, 8 h and 24 h of after androgen withdrawal. Human androgen independent prostate carcinoma cell line PC-3 was also examined as control. Results: Down-regulation of phosphorylated ERK, CDK2, CDK4 and CDK6 and up-regulation of P27kip1 were found initially in LNCaP cell line 8 h after androgen withdrawal. The levels of phosphorylated ERK and CDKs decreased continuously and reached the lowest after 24 h, while continuous elevation of P27kip1 was detected thereafter to 24 h. No expression change of phosphorylated ERK, CDKs and P27kip1 were detected in PC-3 cell line. Conclusion: The androgen withdrawal can cause ERKs activation decrease and cell cycle regulation molecules changes, which may be one of the mechanisms for inhibited growth of androgen dependent prostate carcinoma after androgen ablation by either operative or medicine methods. 展开更多
关键词 prostate neoplasm CARCINOMA ANDROGEN PROLIFERATION cell cycle
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Reproductive Cycle and Seasonal Variations in Lipid Content and Fatty Acid Composition in Gonad of the Cockle Fulvia mutica in Relation to Temperature and Food 被引量:3
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作者 LIU Wenguang LI Qi KONG Lingfeng 《Journal of Ocean University of China》 SCIE CAS 2013年第3期427-433,共7页
From March 2004 to February 2005,seasonal variations in lipid content and fatty acid composition of gonad of the cockle Fulvia mutica(Reeve) were studied on the eastern coast of China in relation to the reproductive c... From March 2004 to February 2005,seasonal variations in lipid content and fatty acid composition of gonad of the cockle Fulvia mutica(Reeve) were studied on the eastern coast of China in relation to the reproductive cycle and environment conditions(e.g.,temperature and food availability).Histological analysis as well as lipid and fatty acid analyses were performed on neutral and polar lipids of the gonad.Results showed that gametogenesis occurred in winter and spring at the expense of lipids previously accumulated in summer and autumn,whereas spawning occurred in summer(20.4-24.6℃).The seasonal variation in lipid content was similar to that of the mean oocyte diameter.In both neutral and polar lipids,the 20:5n-3 and 22:6n-3 levels were relatively higher than saturated fatty acids,and polyunsaturated fatty acids were abundant,with series n-3 as the predominant component.Seasonal variations in the 20:5n-3 and 22:6n-3 levels and the principal n-3 fatty acids were clearly related to the reproductive cycle.The ∑(n-3) and ∑(n-6) values were relatively high during January-May,and the associated unsaturation index was significantly higher than that in other months.The results suggest that fatty acids play an important role in the gametogenesis of F.mutica. 展开更多
关键词 Fulvia mutica LIPIDS fatty acids reproductive cycle FOOD TEMPERATURE
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Effects of photoperiod on daily activity rhythm of juvenile sea cucumber, Apostichopus japonicus (Selenka) 被引量:8
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作者 董贯仓 董双林 +1 位作者 田相利 王芳 《Chinese Journal of Oceanology and Limnology》 SCIE CAS CSCD 2011年第5期1015-1022,共8页
In nature, Apostichopus japonicus exhibits a behavioral characteristic of emerging at night and sheltering during the day. Hence, it was commonly believed that longer and darker light conditions are better for a popul... In nature, Apostichopus japonicus exhibits a behavioral characteristic of emerging at night and sheltering during the day. Hence, it was commonly believed that longer and darker light conditions are better for a population of A. japonicus. In aquaculture situations therefore, animals have commonly been cultured without lighting, especially during juvenile-hatching culture. However, how the length of darkness each day affects .4.japonicus and what the mechanism is of behavioral response of A. japonicus to different photoperiods remain unclear, and are specifically addressed in this study. We applied nine photoperiod treatments (light:dark (LD) cycles at 0:24, 3:21, 6:18, 9:15, 12:12, 15:9, 18:6, 21:3, and 24:0 under 500Ix) to 60 individuals (29.73±0.23 g) per treatment (with 3 replicates). The enviroramental conditions were set as: water temperature = 16.9±0.3℃, dissolved oxygen〉6.0 rag/L, ammonia〈0.3 mg/L, pH=7.8-8.2, and salinity=30-32. Under experimental conditions of continuous darkness as well as continuous light, cyclic nocturnal activity patterns of A. japonicus (viz. the animals emerged and fed at night and sheltered during the day) were observed. However, they spent more and less time, respectively, moving and feeding under continuous darkness and continuous light, than those under a natural light cycle. Under photoperiods with 6-12 h of light, the animals showed one sheltering behavior transition and two emerging behavior transitions. These behavior transitions appeared to be governed by some internal physiological factors and induced by daily light variation. The behavior of the animals was significantly affected by different photoperiods, and the distribution rate (DR) of the animals emerging at "daytime" increased with lengthening "light time" (except for the LD 3:21 cycle). We also found that there was no significant difference in mean DR per day under LD cycles of 6:18, 9:15, 15:9, and 12:12. Mean DRs per day were significantly lower for these photoperiods, than for those under LD cycles of 0:24 and 3:21, and significantly higher than for those under LD cycles of 18:6, 21:3 and 24:0. These results imply that 6-15 h light per day were the similar photoperiods to natural sunlight. From the viewpoint of activity and feeding behaviors, these might be the optimal photoperiods for rearing A. japonicus. 展开更多
关键词 Apostichopusjaponicus daily behavior PHOTOPERIOD
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HRCT Scans of Peripheral Non-Small Cell Lung Cancers and their Relationship with Cyclin D1 Expression:a Longitudinal Study
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作者 Shuhua Ma Linfa Wu +9 位作者 Xiaomao Xu Hongbo Le Xiaoling Cheng Huihong Zhang Zhengyu Sun Zhaoxin Wang Min Wu Wei Mei Zhiguo Hu Yuguang Li 《Chinese Journal of Clinical Oncology》 CSCD 2008年第3期172-178,共7页
OBJECTIVE To investigate cyclin D1 expression in peripheral lung cancers and its relationship with CT signs and prognosis. METHODS Cyclin D1 expression in peripheral lung cancers and its relationship with the CT imagi... OBJECTIVE To investigate cyclin D1 expression in peripheral lung cancers and its relationship with CT signs and prognosis. METHODS Cyclin D1 expression in peripheral lung cancers and its relationship with the CT imaging and prognosis were analyzed retrospectively by means of SP immunohistochemistry and spiral CT scanning in 92 patients with peripheral lung cancer verified by pathology. RESULTS Cyclin D1 expression was related to deep lobulation,spiculate protuberance,short thin spinules sign and mediastina lymph node metastasis.Cyclin D1 expression was not related to tumor size,cavity,pleural indentation,histological type,differentiation,tumor TNM stage,age or sex.Cyclin D1 was a negative prognostic factor whose over-expression indicated a poor prognosis. CONCLUSION Cyclin D1 expression may play an important role in the occurrence,progress and CT scan results of lung cancers.Cyclin D1 was a negative factor whose over-expression implied a poor prognosis.Detection of the cyclin D1 and observation of the CT scan can be considered as indexes of clinical diagnosis and prognostic evaluation. 展开更多
关键词 lung neoplasms cyclin D1 computed tomography.
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内膜转化日激素水平对高龄育龄女性FET妊娠结局的影响
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作者 董颖歌 简宁 腊晓琳 《中国生育健康杂志》 2022年第3期277-280,284,共5页
目的探讨高龄育龄女性内膜转化日激素水平对冻融胚胎移植(FET)妊娠结局的影响。方法回顾性分析2017年1月至2020年6月在新疆医科大学第一附属医院生殖医学中心冻融胚胎移植的资料,共纳入1174例高龄育龄女性(年龄>35岁),调查对象分三... 目的探讨高龄育龄女性内膜转化日激素水平对冻融胚胎移植(FET)妊娠结局的影响。方法回顾性分析2017年1月至2020年6月在新疆医科大学第一附属医院生殖医学中心冻融胚胎移植的资料,共纳入1174例高龄育龄女性(年龄>35岁),调查对象分三组方案:降调节+人工周期组646例,人工周期组222例,自然周期组306例。比较三组在内膜转换日的激素水平及妊娠结局。结果三组的内膜转化日黄体生成素(LH),雌二醇(E_(2)),卵泡刺激素(FSH)水平,内膜转化日内膜厚度,移植胚胎类型,移植日子宫内膜厚度差异有统计学意义;三组的生化妊娠率,种植率,出生体重差异有统计学意义,且两两比较差异均有统计学意义;三组的移植胚胎个数,临床妊娠率,异位妊娠率,多胎妊娠率,流产率,早产率,活产率差异无统计学意义。结论不同内膜准备方案的内膜转化日激素水平对FET妊娠结局无明显影响,但是在FET中对于高龄育龄女性中移植囊胚或许是更好的一种选择。 展开更多
关键词 内膜转化日激素水平 冻融胚胎移植 自然周期 降调+人工周期 人工周期
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Seasonal evolution of circulation and thermal structure in the Yellow Sea
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作者 庞重光 白学志 +1 位作者 白虹 王凡 《Chinese Journal of Oceanology and Limnology》 SCIE CAS CSCD 2005年第3期269-274,共6页
In this paper, the authors used the Princeton Ocean Model (POM) to simulate the seasonal evolu- tions of circulation and thermal structure in the Yellow Sea. The simulated circulation showed that the Yellow Sea Warm C... In this paper, the authors used the Princeton Ocean Model (POM) to simulate the seasonal evolu- tions of circulation and thermal structure in the Yellow Sea. The simulated circulation showed that the Yellow Sea Warm Current (YSWC) was a compensation current of monsoon-driven current, and that in winter, the YSWC became stronger with depth, and could flow across the Bohai Strait in the north. Sensitivity and control- ling tests led to the following conclusions. In winter, the direction of the Yellow Sea Coastal Current in the sur- face layer was controlled partly by tide instead of wind. In summer, a cyclonic horizontal gyre existed in the middle and eastern parts of the Yellow Sea below 10 m. The downwelling in upper layer and upwelling in lower layer were somehow similar to Hu et al. (1991) conceptual model. The calculated thermal structure showed an obvious northward extending YSWC tongue in winter, its position and coverage of the Yellow Sea Cold Water Mass in summer. 展开更多
关键词 seasonal evolution numerical simulation CIRCULATION thermal structure the Yellow Sea
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Integration of light signaling with photoperiodic flowering and circadian rhythm
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作者 Min NI 《Cell Research》 SCIE CAS CSCD 2005年第8期559-566,共8页
Plants become photosynthetic through de-etiolation, a developmental process regulated by red/far-red light-absorbing phytochromes and blue/ultraviolet A light-absorbing cryptochromes. Genetic screens have identified i... Plants become photosynthetic through de-etiolation, a developmental process regulated by red/far-red light-absorbing phytochromes and blue/ultraviolet A light-absorbing cryptochromes. Genetic screens have identified in the last decade many far-red light signaling mutants and several red and blue light signaling mutants, suggesting the existence of distinct red, far-red, or blue light signaling pathways downstream of phytochromes and cryptochromes. However, genetic screens have also identified mutants with defective de-etiolation responses under multiple wavelengths. Thus, the opti- mal de-etiolation responses of a plant depend on coordination among the different light signaling pathways. This review intends to discuss several recently identified signaling components that have a potential role to integrate red, far-red, and blue light signalings. This review also highlights the recent discoveries on proteolytic degradation in the desensitization of light signal transmission, and the tight connection of light signaling with photoperiodic flowering and circadian rhythm. Studies on the controlling mechanisms of de-etiolation, photoperiodic flowering, and circadian rhythm have been the fascinating topics in Arabidopsis research. The knowledge obtained from Arabidopsis can be readily applied to food crops and ornamental species, and can be contributed to our general understanding of signal perception and transduction in all organisms. 展开更多
关键词 circadian regulation CRYPTOCHROMES PHOTOMORPHOGENESIS photoperiodic flowering phytochromes.
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Gametogenic Cycle, the Spawning Season, First Sexual Maturity, and the Biological Minimum Size in Male Ruditapes philippinarum (Bivalvia: Veneridae) in Western Korea
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作者 Ee-Yung Chung Jae Seung Chung Ki-Young Lee 《Journal of Life Sciences》 2013年第6期613-622,共10页
The male gametogenic cycle, spawning season, first sexual maturity, and the biological minimum size in male Ruditapes philippinarum were investigated by qualitative and quantitative reproductive analyses. In the study... The male gametogenic cycle, spawning season, first sexual maturity, and the biological minimum size in male Ruditapes philippinarum were investigated by qualitative and quantitative reproductive analyses. In the study of the male gametogenic cycle by qualitative histological analysis, the gametogenic cycle in male individuals can be classified into five successive stages: (1) early active stage, (2) late active stage, (3) ripe stage, (4) partially spawned stage, and (5) spent and inactive stage. Monthly changes in the gonad index in males measured by qualitative analysis showed a similar pattern to the male gametogenic cycle. In the study of the male gametogenic cycle by quantitative statistical analysis, monthly changes in the portions (%) of areas occupied by the testis areas to total tissue areas showed a rapid increase in March, and reached the maximum in May-June. And also monthly changes in the portions (%) of areas occupied by the spermatogenic stages to the testis area showed a maximum in May and gradually decreased from June to October. Therefore, this species showed a unimodal gametogenic cycle during the year, and the number of spawning seasons occurred once per year, from June to October, with a peak spawning between July and August. The percentage at the first sexual maturity of male clams ranging from 15.1-20.0 mm in shell length was 64.7%, and that of all individuals ranging from over 25.1 mm in shell length was 100%. The biological minimum size (shell lengths at 50% of sexual maturity (RMs0)) of male mature clams that was fitted to an exponential equation was 17.16 mm (considered to be 1 year old). Because harvesting clams less than 17.16 mm in shell length could potentially cause a drastic reduction in recruitment, a measure indicating a prohibitory fishing size should be enacted for adequate fisheries management. 展开更多
关键词 Male Ruditapes philippinarum gametogenic cycle spawning season first sexual maturity biological minimum size.
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