目的探讨吸入β2-受体激动剂(舒喘灵)治疗新生儿暂时性呼吸急促(transient Tachypnea of the Newborn TTN)的疗效,并确定新生儿吸入舒喘灵的安全性.方法将2011年10月至2014年6月入住昆明市妇幼保健院的100例TTN患儿随机分为吸入舒喘灵组...目的探讨吸入β2-受体激动剂(舒喘灵)治疗新生儿暂时性呼吸急促(transient Tachypnea of the Newborn TTN)的疗效,并确定新生儿吸入舒喘灵的安全性.方法将2011年10月至2014年6月入住昆明市妇幼保健院的100例TTN患儿随机分为吸入舒喘灵组(治疗组)52人,未吸入组(对照组)48人,胎龄37周至40+3周.治疗组通过舒喘灵喷雾瓶、储雾罩在入院60 min、6 h分别给予0.4 mg舒喘灵气雾剂吸入;对照组按常规治疗.结果 (1)2组患儿在入院后7、12、24 h呼吸急促、呻吟、吸凹征严重程度比较,治疗组较对照组明显减轻和持续时间明显缩短,差异有统计学意义(P<0.05);(2)治疗组用药前后心率无明显增加,2组心率统计学处理,差异无统计学意义(P>0.05);(3)舒喘灵组需要常压给氧、n CPAP治疗时间较对照组缩短,差异有统计学意义(P<0.05);(4)机械通气治疗:舒喘灵组1例(1.9%)、对照组6例(12.5%),差异有统计学意义(P<0.05);(5)2组入院后12 h监测平均p H值、氧分压、二氧化碳分压转归情况比较,差异有统计学意义(P<0.05);(6)在研究过程中,心电监护无1例心律失常发生;52例治疗组患儿均未出现肌肉震颤症状.结论吸入舒喘灵对新生儿暂时性呼吸急促治疗有明显疗效.且临床和实验室检查均未发现不良反应.展开更多
BACKGROUND: Shortness of breath is a common symptom reported by patients after gynecologic procedures. Delayed traumatic diaphragmatic rupture is a rare cause of shortness of breath. CASE: This report describes the di...BACKGROUND: Shortness of breath is a common symptom reported by patients after gynecologic procedures. Delayed traumatic diaphragmatic rupture is a rare cause of shortness of breath. CASE: This report describes the diagnosis and management of a patient with a delayed presentation of a ruptured right hemidiaphragm after a laparotomy for a pelvic mass. CONCLUSION: Although rare, delayed presentation of traumatic diaphragmatic rupture should be considered in patients with a history of blunt chest or abdominal trauma as a possible cause of shortness of breath in the postoperative setting.展开更多
文摘BACKGROUND: Shortness of breath is a common symptom reported by patients after gynecologic procedures. Delayed traumatic diaphragmatic rupture is a rare cause of shortness of breath. CASE: This report describes the diagnosis and management of a patient with a delayed presentation of a ruptured right hemidiaphragm after a laparotomy for a pelvic mass. CONCLUSION: Although rare, delayed presentation of traumatic diaphragmatic rupture should be considered in patients with a history of blunt chest or abdominal trauma as a possible cause of shortness of breath in the postoperative setting.
