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慢性阻塞性肺疾病的早期诊断生物标志物初筛 被引量:2
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作者 严琼 黄忠辉 +6 位作者 朱卫华 左斌 蓝芬 陈子谓 王钊逸 张艳利 王新明 《中南医学科学杂志》 CAS 2018年第6期616-620,共5页
快速准确的早期诊断技术是有效防治慢性阻塞性肺疾病(COPD)、改善患者生命质量、延长其寿命、降低死亡和减少医疗费用的重要途径,也是当前医学研究中重要前沿科学问题。本研究基于患者呼出气中挥发性有机物携带大量的生理、病理信息,利... 快速准确的早期诊断技术是有效防治慢性阻塞性肺疾病(COPD)、改善患者生命质量、延长其寿命、降低死亡和减少医疗费用的重要途径,也是当前医学研究中重要前沿科学问题。本研究基于患者呼出气中挥发性有机物携带大量的生理、病理信息,利用质子转移反应-飞行时间质谱仪,分析了15例患者和50例健康对照组的呼吸气中挥发性有机物的组分及浓度。初步筛选出18种COPD患者的特征性呼气化合物,其中5种化合物与前人的研究一致,可作为生物标志物应用于COPD的早期诊断。另外13种新发现的化合物,具备作为生物标志物应用于COPD早期诊断的前景,但仍需进一步的研究以证实。本研究丰富了COPD生物标志物库,对于建立非侵入性、快捷的COPD早期诊断方法具有重要支撑作用。 展开更多
关键词 慢性阻塞性肺疾病 呼吸气分析 挥发性有机物 生物标志物 质子转移反应-飞行时间质谱仪
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Path Analysis on the Meteorological Factors Impacting Soil Respiration Rate of Wheat Field 被引量:2
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作者 江晓东 李永秀 《Agricultural Science & Technology》 CAS 2009年第1期74-76,156,共4页
[Objective]The experiment aimed to study the effects of meteorological factors under different weather conditions on soil respiration. [ Method] The path analysis was used to analyze meteorological factors which influ... [Objective]The experiment aimed to study the effects of meteorological factors under different weather conditions on soil respiration. [ Method] The path analysis was used to analyze meteorological factors which influenced soil respiration of wheat field under different weather condition and at jointing stage. [ Result] In sunny day, the correlations between ground temperature at 5 cm, solar radiation, air relative humidity, air temperature and soil respiration were all at significant level while solar radiation and ground temperature at 5 cm were the major factors which influenced soil respiration. In cloudy day, solar radiation was a major factor which influenced soil respiration.[ Conclusion] The soil respiration and surplus path coefficient in sunny day were all higher than these in cloudy day, which demonstrated that except influenced by ground temperature, air temperature, solar radiation and air relative humidity, the soil respiration was also influenced by other factors especially biological factor. 展开更多
关键词 Soil respiration Wheat meteorological factors Path analysis
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