Hepatocellular carcinoma is a highly malignant neoplasm and frequently involves extrahepatic organs but decidedly rarely occurs in brain. We describe 3 cases of brain metastases in patients suffering from post-HBV hep...Hepatocellular carcinoma is a highly malignant neoplasm and frequently involves extrahepatic organs but decidedly rarely occurs in brain. We describe 3 cases of brain metastases in patients suffering from post-HBV hepatocarcinoma. The ＂stroke-like＂ presentation of the cerebral localization of the disease can be explained by both the important vascularization of the tumor and the frequent hemocoagulative alterations caused by the cirrhosis. The importance of diagnostic neuroradiology is briefly addressed, with reference to the fundamental role played by MRI. Surgery of these lesions does not present any particular technical problems as long as they are located in accessible areas and the patient＇s general and neurological conditions allow it. Postoperative radiotherapy seems to improve the quality and quantity of residual life, although the number of patients described in the literature was too small to draw any definite conclusion in this regard.展开更多
Objective: To assess the occurrence of stressful life events in the year before the initiation of systemic sclerosis. Methods: A consecutive series of 40 patients with systemic sclerosis (mean age (56.3±11.9) yea...Objective: To assess the occurrence of stressful life events in the year before the initiation of systemic sclerosis. Methods: A consecutive series of 40 patients with systemic sclerosis (mean age (56.3±11.9) years, mean disease duration (4.3±3.1) years; 32 females and 8 males), including 28 with diffuse cutaneous scleroderma and 12 with limited cutaneous scleroderma, were evaluated. A control group of 40 healthy subjects free of systemic sclerosis also was included. Socioeconomic status was inves- tigated and Paykel's interview for recent life events (a semi-structured research interview covering 64 life events) was conducted. Results: Patients with systemic sclerosis showed higher percentages of lower education (72.5%) and working class (82.5%), and reported more stressful life events (P<0.05), such as exits (P<0.05), undesirable events (P<0.01), and uncontrolled events (P<0.001), when compared with the control. More events that had an objective negative impact (P<0.001) were also reported in systemic sclerosis patients than in the control. These results are in accordance with a multifactorial model of pathogenesis in systemic sclerosis. Conclusion: We reported a strong relationship between stressful life events and the initiation of systemic sclerosis. Our findings are consistent with current understanding of the extensive links of behavioral responses to stress with neurophysiological and biochemical processes.展开更多
Two types of fatigue tests, a rotating bending fatigue test and a three- or four-point bending fatigue test, were carried out on a fine grained WC-Co cemented carbide to evaluate its fatigue crack growth behavior and ...Two types of fatigue tests, a rotating bending fatigue test and a three- or four-point bending fatigue test, were carried out on a fine grained WC-Co cemented carbide to evaluate its fatigue crack growth behavior and fatigue lifetime. From successive observations of the specimen surface during the fatigue process, it was revealed that most of the fatigue lifetime of the tested WC-Co cemented carbide was occupied with crack growth cycles. Using the basic equation of fracture mechanics, the relationship between the fatigue crack growth rate(da/dN) and the maximum stress intensity factor(Kmax) was derived. From this relation, both the values of the threshold intensity factor(Kth) and the fatigue fracture toughness(Kfc) of the material were determined. The fatigue lifetime of the WC-Co cemented carbide was estimated by analysis based on the modified linear elastic fracture mechanics approach. Good agreement between the estimated and experimental fatigue lifetimes was confirmed.展开更多
To accurately track computer viruses,an overlay network that monitors the activities of viruses is constructed.Identifying and locating nodes infected by virus on network is achieved by a naming system in which a node...To accurately track computer viruses,an overlay network that monitors the activities of viruses is constructed.Identifying and locating nodes infected by virus on network is achieved by a naming system in which a node in the network is mapped to a unique serial number of the hard-drive.By carefully monitoring and recording sensitive communication between local system and remote nodes on the network,and suspicious operations on files that originate from remote nodes and entered via some form of file transfer,activities of viruses in both local and network level are recorded and ready for future analysis.These data can also be used in analysis of the mechanism of a computer virus as well as its spreading mode and pattern.展开更多
This paper investigates the rolling contact fatigue of kiln wheels with respect to the axis line deflection, which is linear with the applied supporting loads on wheels. Fatigue crack initiation criteria for elastic s...This paper investigates the rolling contact fatigue of kiln wheels with respect to the axis line deflection, which is linear with the applied supporting loads on wheels. Fatigue crack initiation criteria for elastic shakedown, plastic shakedown and ratcheting material responses are applied to assess wheels responses with two sets of axial line deflection. The finite element simulations are performed by using the bilinear material mode for nonlinear and kinematic hardening in ANSYS 11.0. By comparing the results from different critera, it is showed that the low-cycle fatigue is the predominated failure. Results from different axial line deflections indicate that the optimum adjustment can greatly enhance the whole life of the supporting structure.展开更多
文摘Hepatocellular carcinoma is a highly malignant neoplasm and frequently involves extrahepatic organs but decidedly rarely occurs in brain. We describe 3 cases of brain metastases in patients suffering from post-HBV hepatocarcinoma. The ＂stroke-like＂ presentation of the cerebral localization of the disease can be explained by both the important vascularization of the tumor and the frequent hemocoagulative alterations caused by the cirrhosis. The importance of diagnostic neuroradiology is briefly addressed, with reference to the fundamental role played by MRI. Surgery of these lesions does not present any particular technical problems as long as they are located in accessible areas and the patient＇s general and neurological conditions allow it. Postoperative radiotherapy seems to improve the quality and quantity of residual life, although the number of patients described in the literature was too small to draw any definite conclusion in this regard.
基金Project (No. B340406052) supported by the Science and Technology Foundation of Shanghai Railway Bureau of China
文摘Objective: To assess the occurrence of stressful life events in the year before the initiation of systemic sclerosis. Methods: A consecutive series of 40 patients with systemic sclerosis (mean age (56.3±11.9) years, mean disease duration (4.3±3.1) years; 32 females and 8 males), including 28 with diffuse cutaneous scleroderma and 12 with limited cutaneous scleroderma, were evaluated. A control group of 40 healthy subjects free of systemic sclerosis also was included. Socioeconomic status was inves- tigated and Paykel's interview for recent life events (a semi-structured research interview covering 64 life events) was conducted. Results: Patients with systemic sclerosis showed higher percentages of lower education (72.5%) and working class (82.5%), and reported more stressful life events (P<0.05), such as exits (P<0.05), undesirable events (P<0.01), and uncontrolled events (P<0.001), when compared with the control. More events that had an objective negative impact (P<0.001) were also reported in systemic sclerosis patients than in the control. These results are in accordance with a multifactorial model of pathogenesis in systemic sclerosis. Conclusion: We reported a strong relationship between stressful life events and the initiation of systemic sclerosis. Our findings are consistent with current understanding of the extensive links of behavioral responses to stress with neurophysiological and biochemical processes.
文摘Two types of fatigue tests, a rotating bending fatigue test and a three- or four-point bending fatigue test, were carried out on a fine grained WC-Co cemented carbide to evaluate its fatigue crack growth behavior and fatigue lifetime. From successive observations of the specimen surface during the fatigue process, it was revealed that most of the fatigue lifetime of the tested WC-Co cemented carbide was occupied with crack growth cycles. Using the basic equation of fracture mechanics, the relationship between the fatigue crack growth rate(da/dN) and the maximum stress intensity factor(Kmax) was derived. From this relation, both the values of the threshold intensity factor(Kth) and the fatigue fracture toughness(Kfc) of the material were determined. The fatigue lifetime of the WC-Co cemented carbide was estimated by analysis based on the modified linear elastic fracture mechanics approach. Good agreement between the estimated and experimental fatigue lifetimes was confirmed.
基金Project is supported by the National Nature Science Foundation of China(Grant No.60672142,60772053,90304005)New architecture and technology for the Internet information sharing,The relation and Countermeasure of Application Layer Behavior and Collective Performance of Internet,Forecast of Traffic Model on Internet+1 种基金Supported by National Basic Research Program of China,(Grant No.2007CB307100,Project No.2007CB307105)The Theory of Mobility and Sensor Network under The Integrated Network and the Universal Ap-plicable Service System
文摘To accurately track computer viruses,an overlay network that monitors the activities of viruses is constructed.Identifying and locating nodes infected by virus on network is achieved by a naming system in which a node in the network is mapped to a unique serial number of the hard-drive.By carefully monitoring and recording sensitive communication between local system and remote nodes on the network,and suspicious operations on files that originate from remote nodes and entered via some form of file transfer,activities of viruses in both local and network level are recorded and ready for future analysis.These data can also be used in analysis of the mechanism of a computer virus as well as its spreading mode and pattern.
基金supported by the National Natural Science Foundation of China(No.51075140)Scientific Research Fund of Hunan Provincial Education Department(No.09C407)
文摘This paper investigates the rolling contact fatigue of kiln wheels with respect to the axis line deflection, which is linear with the applied supporting loads on wheels. Fatigue crack initiation criteria for elastic shakedown, plastic shakedown and ratcheting material responses are applied to assess wheels responses with two sets of axial line deflection. The finite element simulations are performed by using the bilinear material mode for nonlinear and kinematic hardening in ANSYS 11.0. By comparing the results from different critera, it is showed that the low-cycle fatigue is the predominated failure. Results from different axial line deflections indicate that the optimum adjustment can greatly enhance the whole life of the supporting structure.
