The existing collaborative recommendation algorithms have lower robustness against shilling attacks.With this problem in mind,in this paper we propose a robust collaborative recommendation algorithm based on k-distanc...The existing collaborative recommendation algorithms have lower robustness against shilling attacks.With this problem in mind,in this paper we propose a robust collaborative recommendation algorithm based on k-distance and Tukey M-estimator.Firstly,we propose a k-distancebased method to compute user suspicion degree(USD).The reliable neighbor model can be constructed through incorporating the user suspicion degree into user neighbor model.The influence of attack profiles on the recommendation results is reduced through adjusting similarities among users.Then,Tukey M-estimator is introduced to construct robust matrix factorization model,which can realize the robust estimation of user feature matrix and item feature matrix and reduce the influence of attack profiles on item feature matrix.Finally,a robust collaborative recommendation algorithm is devised by combining the reliable neighbor model and robust matrix factorization model.Experimental results show that the proposed algorithm outperforms the existing methods in terms of both recommendation accuracy and robustness.展开更多
Two novel adaptive distributed target detectors, the range frequency domain-Rao (RFD-Rao) and range frequency domain-Wald (RFD-Wald) tests are proposed in this work. The application methods for these tests conside...Two novel adaptive distributed target detectors, the range frequency domain-Rao (RFD-Rao) and range frequency domain-Wald (RFD-Wald) tests are proposed in this work. The application methods for these tests consider a partially homogeneous disturbance environment and a target range walking effect in a coherent processing interval (CPI). The asymptotic performance of the detectors is analyzed, and the constant false alarm rate (CFAR) properties with respect to the clutter covariance matrix and power level are shown. The performances of the proposed adaptive detectors are assessed through Monte-Carlo simulations, and the results are presented to demonstrate the effectiveness of the proposed detection algorithms compared to those of similar existing detectors.展开更多
In data post-processing for quantum key distribution, it is essential to have a highly efficient error reconciliation protocol. Based on the key redistribution scheme, we analyze a one-way error reconciliation protoco...In data post-processing for quantum key distribution, it is essential to have a highly efficient error reconciliation protocol. Based on the key redistribution scheme, we analyze a one-way error reconciliation protocol by data simulation. The relationship between the error correction capability and the key generation efficiency of three kinds of Hamming code are demonstrated. The simulation results indicate that when the initial error rates are (0,1.5%], (1.5,4%], and (4,11%], using the Hamming (31,26), (15,11), and (7,4) codes to correct the error, respectively, the key generation rate will be maximized. Based on this, we propose a modified one-way error reconciliation protocol which employs a mixed Hamming code concatenation scheme. The error correction capability and key generation rate are verified through data simulation. Using the parameters of the posterior distribution based on the tested data, a simple method for estimating the bit error rate (BER) with a given confidence interval is estimated. The simulation results show that when the initial bit error rate is 10.00%, after 7 rounds of error correction, the error bits are eliminated completely, and the key generation rate is 10.36%; the BER expectation is 2.96×10^-10, and when the confidence is 95% the corresponding BER upper limit is 2.17×10^-9. By comparison, for the single (7,4) Hamming code error reconciliation scheme at a confidence of 95%,the key generation rate is only 6.09%, while the BER expectation is 5.92x 10"9, with a BER upper limit of 4.34×10^-8. Hence, our improved protocol is much better than the original one.展开更多
Focusing on the reform initiatives of Chinese Academy of Medical Sciences(CAMS) & Peking Union Medical College(PUMC) in medical scientific and technological innovation from perspectives of deepening the reform and...Focusing on the reform initiatives of Chinese Academy of Medical Sciences(CAMS) & Peking Union Medical College(PUMC) in medical scientific and technological innovation from perspectives of deepening the reform and optimizing the ecosystem of science and technology innovation,this article summarizes the highlights of CAMS & PUMC’s efforts in safeguarding people’ s health and promoting the Healthy China 2030 strategy through scientific and technological innovation in the fields including basic research,disease prevention and treatment,and medical technology in the past ten years.These achievements embody the endeavors and responsibility of CAMS& PUMC in realizing self-reliance and self-improvement of Chinese medical science and technology and highlight its contributions to the development of medical science and technology of China.展开更多
Objective To investigate the correlation between subaxial cervical spine instability and cervical spondylotic sympathetic symptoms as well as the difference of cervical spondylotic subaxial instability between male an...Objective To investigate the correlation between subaxial cervical spine instability and cervical spondylotic sympathetic symptoms as well as the difference of cervical spondylotic subaxial instability between male and female patients. Methods We analyzed retrospectively 318 surgical cases of cervical spondylosis treated at Department of Orthopedic Surgery of Peking Union Medical College Hospital between July 2003 and December 2007. All cases were divided into group A without sympathetic symptoms (n=284) and group B with sympathetic symptoms (n=34). Angular and horizontal translation values between two adjacent vertebral bodies from C2 to C7 were measured separately on hyperflexion and hyperextension lateral cervical spine radiographs. Fisher's exact test was used to evaluate the correlation between subaxial cervical instability and sympathetic symptoms. Intragroup correlation between patient gender and subaxial cervical instability was also evaluated. Results Subaxial instability incidences in groups A and B were 21.8% (62/284) and 55.9% (19/34), respectively. Statistical analysis indicated a definite correlation between subaxial cervical instability and sympathetic symptoms (P=0.000). Among patients without sympathetic symptoms, subaxial instability incidences were 21.4% (37/173) in males and 22.5% (25/111) in females, respectively (P=0.883). While among patients with sympathetic symptoms, subaxial instability incidences were 27.3% (3/11) in males and 69.6% (16/23) in females, respectively, indicating significant difference (P=0.030). Subaxial instability was most commonly seen at C4-C5 intervertebral space in sympathetic cervical spondylosis patients. Conclusions High correlation exists between subaxial cervical spine instability and cervical spondylotic sympathetic symptoms, especially in female patients. Hyperextension and hyperflexion radiographs of cervical spine are important to assess sympathetic cervical spondylotic subaxial instability.展开更多
Most of the Radio Frequency IDentification (RFID) authentication protocols, proposed to preserve security and privacy, are analysed to show that they can not provide security against some passive or active attacks. In...Most of the Radio Frequency IDentification (RFID) authentication protocols, proposed to preserve security and privacy, are analysed to show that they can not provide security against some passive or active attacks. In this paper, the security of two matrix-based protocols, proposed by Karthikeyan and Nesterenko (KN protocol) and Ramachandra et al. (RRS protocol) that conform to Electronic Product Code Class-1 Generation-2 (EPC Class-1 Gen-2) standard, are investigated. Using the linear relationship of multiplication of matrix and vector, we point out that both protocols can not provide scalability, and they are vulnerable to passive impersonation attack. In addition, both protocols are totally insecure if the adversary can compromise one tag to extract the secrets. A modified lightweight matrix-based authentication protocol is presented, which can resist mainly common attacks on an RFID authentication system including eavesdropping, relay attack, desynchronization attack, impersonation attack and tag tracking attack. The new protocol also has the desirable scalability property and can keep secure under compromising attack.展开更多
AIM:To conduct a meta-analysis to estimate the determinants of the association between erosive esophagitis (EE)and body mass index(BMI). METHODS:We identified the studies using PubMed. Studies were selected for analys...AIM:To conduct a meta-analysis to estimate the determinants of the association between erosive esophagitis (EE)and body mass index(BMI). METHODS:We identified the studies using PubMed. Studies were selected for analysis based on certain inclusion and exclusion criteria.Data were extracted from each study on the basis of predefined items.Metaanalyses were performed to verify the risk factors,such as obesity and gender. RESULTS:Twenty-one studies were included in this systematic review.These studies demonstrated an association between increasing BMI and the presence of EE[95%confidence interval(CI):1.35-1.88,overweight,odds ratio(OR)=1.60,P value homogeneity =0.003,95%CI:1.65-2.55,obese,OR=2.05,P< 0.01].The heterogeneity disappeared by stratifying for gender.No publication bias was observed in this metaanalysis by the Egger method. CONCLUSION:This analysis demonstrates a positive association between BMI and the presence of EE,especially in males.The risk seems to progressively increase with increasing weight.展开更多
In various environmental studies, geoscience variables not only have the characteristics of time and space, but also are influenced by other variables. Multivariate spatiotemporal variables can improve the accuracy of...In various environmental studies, geoscience variables not only have the characteristics of time and space, but also are influenced by other variables. Multivariate spatiotemporal variables can improve the accuracy of spatiotemporal estimation. Taking the monthly mean ground observation data of the period 1960–2013 precipitation in the Xinjiang Uygur Autonomous Region, China, the spatiotemporal distribution from January to December in 2013 was respectively estimated by space-time Kriging and space-time CoKriging. Modeling spatiotemporal direct variograms and a cross variogram was a key step in space-time CoKriging. Taking the monthly mean air relative humidity of the same site at the same time as the covariates, the spatiotemporal direct variograms and the spatiotemporal cross variogram of the monthly mean precipitation for the period 1960–2013 were modeled. The experimental results show that the space-time CoKriging reduces the mean square error by 31.46% compared with the space-time ordinary Kriging. The correlation coefficient between the estimated values and the observed values of the space-time CoKriging is 5.07% higher than the one of the space-time ordinary Kriging. Therefore, a space-time CoKriging interpolation with air humidity as a covariate improves the interpolation accuracy.展开更多
Based on archival materials discovered in America,Britain,and China,this paper carefully examines the history of the short-lived and completely overlooked Department of Physics in the Premedical School of Peking Union...Based on archival materials discovered in America,Britain,and China,this paper carefully examines the history of the short-lived and completely overlooked Department of Physics in the Premedical School of Peking Union Medical College(PUMC),and uncovers this department’s extensive interconnections with its counterpart at Yenching University.This project also looks into the Master of Science(MS)program in the Department of Physics at Yenching University,which,founded in 1927,was the first graduate program in physics in China.It was this MS program that transformed the Yenching Department from a largely premedical training center serving the PUMC into a prominent cradle of Chinese physics research.This Yenching Department,despite its small faculty and brief existence,nurtured many eminent Chinese physicists,such as Chao-Ying Meng孟昭英,Wen-Yu Chang张文裕,Ming-Chen Wang王明贞,Chia-Liu Luke Yuan袁家骝,Cheng-Shu Wang(Chang)王承书,Ho-Fu Lu卢鹤绂,Ting-Sui Ke葛庭燧,Kun Huang黄昆,and Chia-Lin Hsieh谢家麟.It would have been impossible to achieve these outstanding accomplishments without the effective leadership and pioneering work of C.H.Corbett,P.A.Anderson,Y.M.Hsieh,and W.Band—the first four Department Chairs—in combination with relatively abundant private funding,mostly from America,and extensive educational connections with Western institutions.This paper not only introduces in detail these four department heads and their contributions,but also discloses the unique role played by the Rockefeller Foundation via the China Medical Board and the PUMC in the development of the Yenching Department of Physics.展开更多
基金National Natural Science Foundation of China under Grant No.61379116,Natural Science Foundation of Hebei Province under Grant No.F2015203046 and No.F2013203124,Key Program of Research on Science and Technology of Higher Education Institutions of Hebei Province under Grant No.ZH2012028
文摘The existing collaborative recommendation algorithms have lower robustness against shilling attacks.With this problem in mind,in this paper we propose a robust collaborative recommendation algorithm based on k-distance and Tukey M-estimator.Firstly,we propose a k-distancebased method to compute user suspicion degree(USD).The reliable neighbor model can be constructed through incorporating the user suspicion degree into user neighbor model.The influence of attack profiles on the recommendation results is reduced through adjusting similarities among users.Then,Tukey M-estimator is introduced to construct robust matrix factorization model,which can realize the robust estimation of user feature matrix and item feature matrix and reduce the influence of attack profiles on item feature matrix.Finally,a robust collaborative recommendation algorithm is devised by combining the reliable neighbor model and robust matrix factorization model.Experimental results show that the proposed algorithm outperforms the existing methods in terms of both recommendation accuracy and robustness.
基金Project(61771367) supported by the National Natural Science Foundation of China
文摘Two novel adaptive distributed target detectors, the range frequency domain-Rao (RFD-Rao) and range frequency domain-Wald (RFD-Wald) tests are proposed in this work. The application methods for these tests consider a partially homogeneous disturbance environment and a target range walking effect in a coherent processing interval (CPI). The asymptotic performance of the detectors is analyzed, and the constant false alarm rate (CFAR) properties with respect to the clutter covariance matrix and power level are shown. The performances of the proposed adaptive detectors are assessed through Monte-Carlo simulations, and the results are presented to demonstrate the effectiveness of the proposed detection algorithms compared to those of similar existing detectors.
基金supported in part by the Foundation for Key Program of Chinese Ministry of Education under Grant No.212177Scientific Research Foundation of the Education Department of Shaanxi Province under Grant No.12JK0973
文摘In data post-processing for quantum key distribution, it is essential to have a highly efficient error reconciliation protocol. Based on the key redistribution scheme, we analyze a one-way error reconciliation protocol by data simulation. The relationship between the error correction capability and the key generation efficiency of three kinds of Hamming code are demonstrated. The simulation results indicate that when the initial error rates are (0,1.5%], (1.5,4%], and (4,11%], using the Hamming (31,26), (15,11), and (7,4) codes to correct the error, respectively, the key generation rate will be maximized. Based on this, we propose a modified one-way error reconciliation protocol which employs a mixed Hamming code concatenation scheme. The error correction capability and key generation rate are verified through data simulation. Using the parameters of the posterior distribution based on the tested data, a simple method for estimating the bit error rate (BER) with a given confidence interval is estimated. The simulation results show that when the initial bit error rate is 10.00%, after 7 rounds of error correction, the error bits are eliminated completely, and the key generation rate is 10.36%; the BER expectation is 2.96×10^-10, and when the confidence is 95% the corresponding BER upper limit is 2.17×10^-9. By comparison, for the single (7,4) Hamming code error reconciliation scheme at a confidence of 95%,the key generation rate is only 6.09%, while the BER expectation is 5.92x 10"9, with a BER upper limit of 4.34×10^-8. Hence, our improved protocol is much better than the original one.
文摘Focusing on the reform initiatives of Chinese Academy of Medical Sciences(CAMS) & Peking Union Medical College(PUMC) in medical scientific and technological innovation from perspectives of deepening the reform and optimizing the ecosystem of science and technology innovation,this article summarizes the highlights of CAMS & PUMC’s efforts in safeguarding people’ s health and promoting the Healthy China 2030 strategy through scientific and technological innovation in the fields including basic research,disease prevention and treatment,and medical technology in the past ten years.These achievements embody the endeavors and responsibility of CAMS& PUMC in realizing self-reliance and self-improvement of Chinese medical science and technology and highlight its contributions to the development of medical science and technology of China.
文摘Objective To investigate the correlation between subaxial cervical spine instability and cervical spondylotic sympathetic symptoms as well as the difference of cervical spondylotic subaxial instability between male and female patients. Methods We analyzed retrospectively 318 surgical cases of cervical spondylosis treated at Department of Orthopedic Surgery of Peking Union Medical College Hospital between July 2003 and December 2007. All cases were divided into group A without sympathetic symptoms (n=284) and group B with sympathetic symptoms (n=34). Angular and horizontal translation values between two adjacent vertebral bodies from C2 to C7 were measured separately on hyperflexion and hyperextension lateral cervical spine radiographs. Fisher's exact test was used to evaluate the correlation between subaxial cervical instability and sympathetic symptoms. Intragroup correlation between patient gender and subaxial cervical instability was also evaluated. Results Subaxial instability incidences in groups A and B were 21.8% (62/284) and 55.9% (19/34), respectively. Statistical analysis indicated a definite correlation between subaxial cervical instability and sympathetic symptoms (P=0.000). Among patients without sympathetic symptoms, subaxial instability incidences were 21.4% (37/173) in males and 22.5% (25/111) in females, respectively (P=0.883). While among patients with sympathetic symptoms, subaxial instability incidences were 27.3% (3/11) in males and 69.6% (16/23) in females, respectively, indicating significant difference (P=0.030). Subaxial instability was most commonly seen at C4-C5 intervertebral space in sympathetic cervical spondylosis patients. Conclusions High correlation exists between subaxial cervical spine instability and cervical spondylotic sympathetic symptoms, especially in female patients. Hyperextension and hyperflexion radiographs of cervical spine are important to assess sympathetic cervical spondylotic subaxial instability.
基金Supported by the Priority Academic Program Development of Jiangsu Higher Education Institutions (PAPD)the National Natural Science Foundation of China (No.60903181)Nanjing University of Posts and Telecommunications Funds (No.NY208072)
文摘Most of the Radio Frequency IDentification (RFID) authentication protocols, proposed to preserve security and privacy, are analysed to show that they can not provide security against some passive or active attacks. In this paper, the security of two matrix-based protocols, proposed by Karthikeyan and Nesterenko (KN protocol) and Ramachandra et al. (RRS protocol) that conform to Electronic Product Code Class-1 Generation-2 (EPC Class-1 Gen-2) standard, are investigated. Using the linear relationship of multiplication of matrix and vector, we point out that both protocols can not provide scalability, and they are vulnerable to passive impersonation attack. In addition, both protocols are totally insecure if the adversary can compromise one tag to extract the secrets. A modified lightweight matrix-based authentication protocol is presented, which can resist mainly common attacks on an RFID authentication system including eavesdropping, relay attack, desynchronization attack, impersonation attack and tag tracking attack. The new protocol also has the desirable scalability property and can keep secure under compromising attack.
文摘AIM:To conduct a meta-analysis to estimate the determinants of the association between erosive esophagitis (EE)and body mass index(BMI). METHODS:We identified the studies using PubMed. Studies were selected for analysis based on certain inclusion and exclusion criteria.Data were extracted from each study on the basis of predefined items.Metaanalyses were performed to verify the risk factors,such as obesity and gender. RESULTS:Twenty-one studies were included in this systematic review.These studies demonstrated an association between increasing BMI and the presence of EE[95%confidence interval(CI):1.35-1.88,overweight,odds ratio(OR)=1.60,P value homogeneity =0.003,95%CI:1.65-2.55,obese,OR=2.05,P< 0.01].The heterogeneity disappeared by stratifying for gender.No publication bias was observed in this metaanalysis by the Egger method. CONCLUSION:This analysis demonstrates a positive association between BMI and the presence of EE,especially in males.The risk seems to progressively increase with increasing weight.
基金Project(17D02)supported by the Open Fund of State Laboratory of Information Engineering in Surveying,Mapping and Remote Sensing,Wuhan University,ChinaProject supported by the State Key Laboratory of Satellite Navigation System and Equipment Technology,China
文摘In various environmental studies, geoscience variables not only have the characteristics of time and space, but also are influenced by other variables. Multivariate spatiotemporal variables can improve the accuracy of spatiotemporal estimation. Taking the monthly mean ground observation data of the period 1960–2013 precipitation in the Xinjiang Uygur Autonomous Region, China, the spatiotemporal distribution from January to December in 2013 was respectively estimated by space-time Kriging and space-time CoKriging. Modeling spatiotemporal direct variograms and a cross variogram was a key step in space-time CoKriging. Taking the monthly mean air relative humidity of the same site at the same time as the covariates, the spatiotemporal direct variograms and the spatiotemporal cross variogram of the monthly mean precipitation for the period 1960–2013 were modeled. The experimental results show that the space-time CoKriging reduces the mean square error by 31.46% compared with the space-time ordinary Kriging. The correlation coefficient between the estimated values and the observed values of the space-time CoKriging is 5.07% higher than the one of the space-time ordinary Kriging. Therefore, a space-time CoKriging interpolation with air humidity as a covariate improves the interpolation accuracy.
文摘Based on archival materials discovered in America,Britain,and China,this paper carefully examines the history of the short-lived and completely overlooked Department of Physics in the Premedical School of Peking Union Medical College(PUMC),and uncovers this department’s extensive interconnections with its counterpart at Yenching University.This project also looks into the Master of Science(MS)program in the Department of Physics at Yenching University,which,founded in 1927,was the first graduate program in physics in China.It was this MS program that transformed the Yenching Department from a largely premedical training center serving the PUMC into a prominent cradle of Chinese physics research.This Yenching Department,despite its small faculty and brief existence,nurtured many eminent Chinese physicists,such as Chao-Ying Meng孟昭英,Wen-Yu Chang张文裕,Ming-Chen Wang王明贞,Chia-Liu Luke Yuan袁家骝,Cheng-Shu Wang(Chang)王承书,Ho-Fu Lu卢鹤绂,Ting-Sui Ke葛庭燧,Kun Huang黄昆,and Chia-Lin Hsieh谢家麟.It would have been impossible to achieve these outstanding accomplishments without the effective leadership and pioneering work of C.H.Corbett,P.A.Anderson,Y.M.Hsieh,and W.Band—the first four Department Chairs—in combination with relatively abundant private funding,mostly from America,and extensive educational connections with Western institutions.This paper not only introduces in detail these four department heads and their contributions,but also discloses the unique role played by the Rockefeller Foundation via the China Medical Board and the PUMC in the development of the Yenching Department of Physics.