A facile reaction of aryl Grignard reagents with 4-alkylacetophenones under ultrasonic irradiation is reported. The reaction can be completed within two minutes with a conversion of 15%～95% and gives 1,1-diarylethene...A facile reaction of aryl Grignard reagents with 4-alkylacetophenones under ultrasonic irradiation is reported. The reaction can be completed within two minutes with a conversion of 15%～95% and gives 1,1-diarylethene and tertiary alcohol in the selectivity over 60%～96%(sometimes with 94.4% 1,1-diarylethene ).展开更多
A series of 2-aryl-4,5-diphenylimidazoles were synthesized by one-step condensation reaction of （aromatic） aldehyde, diphenyl diketone and ammonium acetate（molar ratio 112） in acetic acid under microwave irradiati...A series of 2-aryl-4,5-diphenylimidazoles were synthesized by one-step condensation reaction of （aromatic） aldehyde, diphenyl diketone and ammonium acetate（molar ratio 112） in acetic acid under microwave irradiation. Products were characterized by mp, IR, (1H NMR), MS and elemental analysis, and their melting points are identical to those of the known compounds reported in the literature. The reaction time was 411 min and the yield 70%98%. Its a low energy （consumption）, environmentally benign, and easy process.展开更多
In this paper, CoMFA method was applied to study the 3D QSAR on a series of 3 anilinomethylene 6 alkyl (aryl) 5,6 2H dihydropyran 2, 4 dione compounds, which were designed and synthesized referring to the natural toxi...In this paper, CoMFA method was applied to study the 3D QSAR on a series of 3 anilinomethylene 6 alkyl (aryl) 5,6 2H dihydropyran 2, 4 dione compounds, which were designed and synthesized referring to the natural toxic Alternaric acid structure. The results displayed the information on modification of primary molecules and further synthesis of new bioactive compounds.展开更多
文摘A facile reaction of aryl Grignard reagents with 4-alkylacetophenones under ultrasonic irradiation is reported. The reaction can be completed within two minutes with a conversion of 15%～95% and gives 1,1-diarylethene and tertiary alcohol in the selectivity over 60%～96%(sometimes with 94.4% 1,1-diarylethene ).
文摘A series of 2-aryl-4,5-diphenylimidazoles were synthesized by one-step condensation reaction of （aromatic） aldehyde, diphenyl diketone and ammonium acetate（molar ratio 112） in acetic acid under microwave irradiation. Products were characterized by mp, IR, (1H NMR), MS and elemental analysis, and their melting points are identical to those of the known compounds reported in the literature. The reaction time was 411 min and the yield 70%98%. Its a low energy （consumption）, environmentally benign, and easy process.
文摘In this paper, CoMFA method was applied to study the 3D QSAR on a series of 3 anilinomethylene 6 alkyl (aryl) 5,6 2H dihydropyran 2, 4 dione compounds, which were designed and synthesized referring to the natural toxic Alternaric acid structure. The results displayed the information on modification of primary molecules and further synthesis of new bioactive compounds.
