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四谈肝与咳喘哮——肝气虚所致咳喘哮证治述要 被引量:6
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作者 武维屏 高伟 《天津中医药大学学报》 CAS 2021年第6期714-718,共5页
因肝肺关系密切,肝肺不和是诱发咳喘哮的重要病理机制。肝气虚致咳喘哮者临床并不少见,但两者之间的联系却甚少论及。本文试从肝气虚的识别要点、肝气虚诱发咳喘哮机制、表现及具体治法方药进行论述,以期进一步扩展、完善调肝理肺理论,... 因肝肺关系密切,肝肺不和是诱发咳喘哮的重要病理机制。肝气虚致咳喘哮者临床并不少见,但两者之间的联系却甚少论及。本文试从肝气虚的识别要点、肝气虚诱发咳喘哮机制、表现及具体治法方药进行论述,以期进一步扩展、完善调肝理肺理论,指导临床。 展开更多
关键词 咳喘哮 肝气虚 调肝理肺
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中西医结合治疗小儿咳喘哮50例 被引量:1
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作者 杜旭隆 杨玉虎 席武 《四川中医》 2009年第7期91-92,共2页
目的:观察咳喘消方配合西医抗病毒、抗过敏、抗菌、止咳、平喘治疗小儿咳喘哮的疗效。结果:治愈49例,治愈率98%。结论:中西医结合治疗小儿咳喘哮,收效良好。
关键词 中西医结合治疗 小儿 咳喘哮 咳喘消方
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五谈肝与咳、喘、哮——肝与枢机密切相关对肺之影响 被引量:2
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作者 武维屏 高伟 《天津中医药大学学报》 CAS 2022年第4期417-420,共4页
探讨少阳、少阴分别作为三阳、三阴枢机对维持人体正常生命活动的影响,分析肝在人体枢机运转中的作用,阐释肝与枢机失畅而致咳喘哮病机的相关性,并归纳小柴胡汤、四逆散分别作为三阳与三阴枢机主方治疗咳喘哮的临床思路。
关键词 咳喘哮 少阳 少阴 枢机 小柴胡汤 四逆散
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哮咳喘颗粒的止咳化痰作用 被引量:4
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作者 耿志辉 李天舒 +1 位作者 李晓辕 耿玮峥 《中国老年学杂志》 CAS CSCD 北大核心 2014年第12期3401-3402,共2页
目的探讨哮咳喘颗粒的止咳、化痰作用在临床治疗中的评价。方法分别采用豚鼠枸橼酸钠喷雾法、气管段酚红法对哮咳喘颗粒的止咳、化痰作用进行实验研究。结果哮咳喘颗粒对豚鼠咳嗽潜伏期、5 min咳嗽次数与生理盐水组比较显著差异(P<0.... 目的探讨哮咳喘颗粒的止咳、化痰作用在临床治疗中的评价。方法分别采用豚鼠枸橼酸钠喷雾法、气管段酚红法对哮咳喘颗粒的止咳、化痰作用进行实验研究。结果哮咳喘颗粒对豚鼠咳嗽潜伏期、5 min咳嗽次数与生理盐水组比较显著差异(P<0.001);哮咳喘颗粒祛痰作用明显,对小鼠酚红排出量有明显的影响,与生理盐水组比较差异显著(P<0.001)。结论哮咳喘颗粒具有明显止咳、化痰作用。 展开更多
关键词 咳喘颗粒 豚鼠 止咳 化痰
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小儿哮咳喘颗粒对感染流感病毒小鼠保护作用的观察 被引量:1
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作者 耿志辉 刘利 李天书 《中国病原生物学杂志》 CSCD 2008年第8期579-581,共3页
目的观察小儿哮咳喘颗粒对感染流感病毒小鼠的影响及体外抑菌和抗病毒作用。方法昆明小鼠灌胃不同浓度的小儿哮喘溶液1次/d,连续7d,末次给药后4h经鼻滴入流感病毒,观察7d,记录小鼠死亡率,试验设病毒灵对照和空白对照;常规方法做体外抑... 目的观察小儿哮咳喘颗粒对感染流感病毒小鼠的影响及体外抑菌和抗病毒作用。方法昆明小鼠灌胃不同浓度的小儿哮喘溶液1次/d,连续7d,末次给药后4h经鼻滴入流感病毒,观察7d,记录小鼠死亡率,试验设病毒灵对照和空白对照;常规方法做体外抑菌试验;以Hep-2传代细胞进行传代培养,观察小儿哮咳喘颗粒最大无毒剂量(TD0)、细胞半数感染量(TCID50)以及不同剂量受试药物对感染病毒细胞的保护作用。结果小儿哮咳喘颗粒组感染病毒动物死亡率为100%,阴性对照组死亡率为0。在体外试验显示,小儿哮咳喘颗粒对肺炎双球菌和流感杆菌等多种细菌有明显的抑制作用,对流感病毒和柯萨奇病毒所致的细胞病变均明显减轻。结论小儿哮咳喘颗粒具有抑菌和抗病毒作用,对感染流感病毒小鼠有明显的保护作用。 展开更多
关键词 小儿咳喘颗粒 抑菌 抗病毒 小鼠
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哮咳喘颗粒抗炎作用的实验研究 被引量:1
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作者 杨健 李秉钧 《长春中医药大学学报》 2008年第6期644-645,共2页
目的:观察哮咳喘颗粒的抗炎作用。方法:采用二甲苯致小鼠耳炎症的方法观察其抗炎作用,采用醋酸致小鼠腹腔毛细血管通透性增加的方法观察其抗炎作用,采用角叉菜胶致大鼠足跖肿胀的方法观察其抗炎作用。结果:哮咳喘颗粒对二甲苯所致的小... 目的:观察哮咳喘颗粒的抗炎作用。方法:采用二甲苯致小鼠耳炎症的方法观察其抗炎作用,采用醋酸致小鼠腹腔毛细血管通透性增加的方法观察其抗炎作用,采用角叉菜胶致大鼠足跖肿胀的方法观察其抗炎作用。结果:哮咳喘颗粒对二甲苯所致的小鼠耳肿胀有明显的抑制作用,对醋酸所致的小鼠腹腔毛细血管通透性增加有明显的抑制作用,并对角叉菜胶所致的大鼠足跖肿胀有明显的抑制作用。结论:哮喘喘颗粒具有良好的抗炎作用。 展开更多
关键词 咳喘颗粒 耳肿胀 足肿胀 毛细血管通透性 小鼠
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小儿哮咳喘胶囊治疗小儿哮喘发作期100例 被引量:2
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作者 丁利忠 孙丽平 王延博 《中国中医药现代远程教育》 2016年第5期43-44,共2页
目的观察小儿哮咳喘胶囊治疗小儿哮喘发作期的临床疗效。方法选200例哮喘发作期患儿,随机分为治疗及对照组,每组100例。治疗组给予小儿哮咳喘胶囊治疗,对照组采用小儿咳喘灵颗粒治疗,疗程5~7天,对比两组患儿的疗效区别。结果治疗组总有... 目的观察小儿哮咳喘胶囊治疗小儿哮喘发作期的临床疗效。方法选200例哮喘发作期患儿,随机分为治疗及对照组,每组100例。治疗组给予小儿哮咳喘胶囊治疗,对照组采用小儿咳喘灵颗粒治疗,疗程5~7天,对比两组患儿的疗效区别。结果治疗组总有效率达90%,对照组总有效率为64%,两组患儿临床疗效比较P〈0.05,具有统计学意义。结论小儿哮咳喘胶囊治疗小儿哮喘发作期,可以更全安有效的控制症状,提高临床疗效。 展开更多
关键词 发作期 小儿咳喘胶囊 中成药疗法
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小儿哮咳喘胶囊药效学机制的实验研究 被引量:1
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作者 李静 许继增 张永和 《中国社区医师(医学专业)》 2007年第23期11-11,共1页
目的:观察小儿哮咳喘胶囊对大鼠、小鼠、豚鼠的抗炎、镇咳、祛痰、平喘等药效作用,为其广泛临床应用提供依据。方法:对大鼠、小鼠、豚鼠随机分组,并分别考查小儿哮咳喘胶囊对甲醛致大鼠踝关节肿胀度的影响,对二甲苯所致小鼠耳壳炎症反... 目的:观察小儿哮咳喘胶囊对大鼠、小鼠、豚鼠的抗炎、镇咳、祛痰、平喘等药效作用,为其广泛临床应用提供依据。方法:对大鼠、小鼠、豚鼠随机分组,并分别考查小儿哮咳喘胶囊对甲醛致大鼠踝关节肿胀度的影响,对二甲苯所致小鼠耳壳炎症反应的影响,对二氧化硫致小鼠咳嗽的影响,对小鼠气管段酚红排泄量的影响,以及对豚鼠引喘潜伏期的影响。结果:小儿哮咳喘胶囊对甲醛致大鼠足踝肿胀及二甲苯致小鼠耳壳炎症均有显著抑制作用,并能显著性抑制二氧化硫所致小鼠咳嗽反应;对小鼠气管排泄酚红及排痰量有显著促进;明显增长豚鼠引喘潜伏期。结论:小儿哮咳喘胶囊有明显抗炎、镇咳、祛痰、平喘作用,上述作用可能是其临床疗效的主要药理学基础。 展开更多
关键词 小儿咳喘胶囊 大鼠 小鼠 豚鼠 实验研究
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哮咳喘颗粒对小鼠免疫功能的影响
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作者 耿志辉 魏清 +1 位作者 李晓辕 耿玮峥 《中国老年学杂志》 CAS CSCD 北大核心 2013年第17期4218-4219,共2页
目的研究哮咳喘颗粒对小鼠免疫功能的影响。方法通过紫外分光光度法测定小鼠单核-巨噬细胞对血流中碳粒的清除能力。测定小鼠足肿胀度,观察哮咳喘颗粒对二硝基氯苯所致小鼠迟发型变态反应的影响。结果哮咳喘颗粒9、12 g/kg剂量能明显提... 目的研究哮咳喘颗粒对小鼠免疫功能的影响。方法通过紫外分光光度法测定小鼠单核-巨噬细胞对血流中碳粒的清除能力。测定小鼠足肿胀度,观察哮咳喘颗粒对二硝基氯苯所致小鼠迟发型变态反应的影响。结果哮咳喘颗粒9、12 g/kg剂量能明显提高小鼠单核-巨噬细胞对血流中碳粒的清除能力;12 g/kg剂量能明显增强二硝基氯苯诱导的小鼠迟发型变态反应。结论哮咳喘颗粒能增强机体的免疫功能。 展开更多
关键词 咳喘颗粒 免疫功能
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小儿哮咳喘冲剂配合西医治疗毛细支气管炎82例临床研究
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作者 安笑然 原晓风 +4 位作者 丛丽 冯晓纯 孙丽平 李静 李香玉 《中国临床医生杂志》 2004年第7期43-44,共2页
关键词 毛细支气管炎 临床研究 小儿咳喘冲剂 儿童 中西医结合治疗
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小儿哮咳喘胶囊治疗婴幼儿哮喘的临床观察
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作者 李静 许继增 《世界中西医结合杂志》 2007年第11期646-648,共3页
目的:观察小儿哮咳喘胶囊治疗婴幼儿哮喘的疗效,并探讨其作用机制。方法:将60例婴幼儿哮喘患者随机分为两组,每组30例,治疗组以解毒开肺为法的小儿哮咳喘胶囊治疗,对照组以清肺化痰为法的贝羚胶囊治疗,对比其疗效。结果:治疗组临床控制1... 目的:观察小儿哮咳喘胶囊治疗婴幼儿哮喘的疗效,并探讨其作用机制。方法:将60例婴幼儿哮喘患者随机分为两组,每组30例,治疗组以解毒开肺为法的小儿哮咳喘胶囊治疗,对照组以清肺化痰为法的贝羚胶囊治疗,对比其疗效。结果:治疗组临床控制11例,显效9例,有效4例,无效6例,总有效率86.67%;对照组临床控制4例,显效6例,11例,无效9例,总有效率70.00%,两组总有效率经统计学处理有显著性差异(P<0.05)。治疗组在临床主要症状、体征的改善方面也优于对照组(P<0.05,P<0.01)。结论:婴幼儿哮咳喘胶囊为治疗小儿哮喘的有效复方制剂,值得进一步推广应用。 展开更多
关键词 婴幼儿 解毒开肺法 小儿咳喘胶囊
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哮咳饮治疗咳嗽变异性哮喘(咳期)疗效观察 被引量:3
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作者 马晓丽 冯晓纯 《吉林中医药》 2008年第2期115-115,共1页
关键词 咳饮 咳喘胶囊 咳嗽变异性(咳期) 疗效观察
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Observation on clinical effects of tuina plus montelukast sodium tablets for children with cough variant asthma 被引量:8
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作者 叶康 黄国琪 《Journal of Acupuncture and Tuina Science》 CSCD 2017年第5期349-353,共5页
Objective: To observe the clinical effects of tuina plus oral administration of montelukast sodium tablets for children with cough variant asthma (CVA). Methods: A hundred and six children with CVA were randomly d... Objective: To observe the clinical effects of tuina plus oral administration of montelukast sodium tablets for children with cough variant asthma (CVA). Methods: A hundred and six children with CVA were randomly divided into a treatment group and a control group, 53 cases in each group. The treatment group was treated with Tuina therapy plus oral administration of montelukast sodium tablets, and the control group was treated only by oral administration of montelukast sodium tablets. Tuina treatment was given three times per week. 5 mg of montelukast sodium tablets was given orally before bedtime every night. The therapeutic effects were assessed after the treatment of four weeks in both groups. Results: The total effective rates were 92.5% in the treatment group and 77.4% in the control group. The difference in the total effective rate between the two groups was statistically significant (P〈0.05). Conclusion: The therapeutic effect of tuina plus montelukast sodium tablets for children with CVA is better than that of oral administration of montelukast sodium tablets alone. 展开更多
关键词 TUINA MASSAGE COUGH ASTHMA MONTELUKAST Child Preschool
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Manipulation parameter optimization in Liu's back tuina therapy for kids'cough variant asthma in remission stage 被引量:8
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作者 Li Xue Zhu Bin-ye +1 位作者 Shao Xiang-ning Hong Jue 《Journal of Acupuncture and Tuina Science》 CSCD 2020年第1期67-74,共8页
Objective:To determine the optimal manipulation parameters in Liu's back tuina therapy for remission-stage cough variant asthma(CVA)in kids.Methods:A 5-factor 3-level L18(37)orthogonal design was adopted.The exper... Objective:To determine the optimal manipulation parameters in Liu's back tuina therapy for remission-stage cough variant asthma(CVA)in kids.Methods:A 5-factor 3-level L18(37)orthogonal design was adopted.The experimental factors and levels were selected:A,the number of times of Rou-kneading Feishu(BL 13);B,the frequency of Rou-kneading Feishu(BL 13);C,the number of times of Tui-pushing in a'介'-like pattern;D,the frequency of Tui-pushing in a'介'-like pattern;E,the intensity of red color after Ca-scrubbing Feishu(BL 13)with salt.A1,A2 and A3 stood for 10 times,20 times and 30 times,respectively;B1,B2 and B3 stood for 200 times/min,240 times/min and 280 times/min,respectively;C1,C2 and C3 stood for 50 times,75 times and 100 times,respectively;D1,D2 and D3 stood for 150 times/min,175 times/min and 200 times/min,respectively;E1,E2 and E3 stood for pinkish,bright red and dark red,respectively.A total of 108 kids with CVA in remission stage were divided into 18 groups using the random number table method,with 6 cases in each group.Changes in the cough score and fractional exhaled nitric oxide(FENO)level were observed after 15-day treatment.Results:The cough score and FENO level changed significantly in every group after treatment(all P<0.01).By the effect in improving cough score,the factors were listed as D,B,A,C and E in descending order;the most optimal manipulation parameter combination was group 17(A3B2C1D3E1);the second optimal parameter combinations were group 7(A3B1C2D1E3),group 13(A2B1C2D3E1)and group 14(A2B2C3D1E2).Regarding the effect in down-regulating the level of FENO,the factors were listed as C,A,E,B and D in descending order;the most optimal manipulation parameter combination was group 13(A2B1C2D3E1);the second optimal parameter combinations were group 18(A3B3C2D1E2),group 16(A3B1C3D2E3)and group 14(A2B2C3D1E2).Conclusion:Two most effective manipulation parameter combinations were selected out of 18 different parameter combinations in Liu's back tuina therapy for remission-stage CVA in kids.Doctors can choose an appropriate manipulation based on the symptom features of the disease. 展开更多
关键词 TUINA MASSAGE Pediatric Tuina Orthogonal Design COUGH Asthma Child Preschool
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Clinical Observation on Acupoint Application in the Hottest Summer Days for Asthmatic Diseases 被引量:6
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作者 齐昌菊 《Journal of Acupuncture and Tuina Science》 2010年第3期189-190,共2页
Objective: To observe the clinical effects of acupoint application therapy for asthmatic diseases in the hottest of summer days. Methods: 500 cases of patients with asthmatic diseases were treated by applying a herb... Objective: To observe the clinical effects of acupoint application therapy for asthmatic diseases in the hottest of summer days. Methods: 500 cases of patients with asthmatic diseases were treated by applying a herbal drug on the acupoints in the hottest summer days, namely herbal cake stuck on the acupoint with a piece of plaster, for 6 h every time, once respectively in the first, second and third period of the hottest summer days. Six months after the last session, the clinical effects were assessed by questionnaire. Results: In 500 cases of the patients, the results showed a remarkable effect in 267 cases, improvement in 182 cases, failure in 51 cases and the effective rate was 89.9%. Conclusion: The therapeutic effects are positive in the application of a herbal drug on an acupoint for asthmatic diseases. This method is convenient and needs to be popularized clinically. 展开更多
关键词 Acupoint Sticking Therapy Chinese Medicinal Natural Moxibustion COUGH ASTHMA
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Effect and mechanism of application in canicular days plus enteral nutrition for cough variant asthma in kids 被引量:5
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作者 郑苏 罗强 +3 位作者 彭力 胥婧 穆敬平 洪珏(译) 《Journal of Acupuncture and Tuina Science》 CSCD 2016年第5期333-339,共7页
Objective: To observe the clinical efficacy of application in canicular days plus enteral nutrition in treating cough variant asthma (CVA) in kids, and to explore its action mechanism. Methods: Following a randomi... Objective: To observe the clinical efficacy of application in canicular days plus enteral nutrition in treating cough variant asthma (CVA) in kids, and to explore its action mechanism. Methods: Following a randomized controlled single-blind parallel-group design, 138 eligible kids with CVA were randomized into an observation group, a canicular-day application group, and an enteral nutrition group, 46 kids in each group. The canicular-day application group was intervened by application in canicular days, the enteral nutrition group was by enteral feeding, and the observation group was by both canicular-day application and enteral feeding. The therapeutic efficacies were evaluated after a treatment course. Results: The recovery rate and total effective rate were respectively 50.0% and 98.0% in the observation group, versus 23.9% and 91.3% in the canicular-day application group, and 13.0% and 78.6% in the enteral nutrition group. The observation group was significantly superior to the other two groups (both P〈0.05). In comparing the global symptom score, peak expiratory flow (PEF), forced expiratory volume in one second (FEVl), CD3^+, CD4^+, CD4^+/CD8^+, CD8^+, hemoglobin (Hb), total protein (TP), albumin (ALB), eosinophil cationic protein (ECP), lipid peroxide (LPO), leukotriene (LT), body weight (BW), triceps skin-fold (TSF), and arm muscle circumference (AMC), the observation group was significantly better than the other two groups (both P〈0.05). Conclusion: Application in canicular days plus enteral nutrition can significantly improve the pulmonary function and symptoms in children's CVA, and the effect is possibly produced by regulating cellular immune system, enhancing Hb, TP, ALB, BW, TSF, AMC, and inhibiting the production of ECP, LPO, and LT. 展开更多
关键词 Moxibustion Therapy COUGH ASTHMA Enteral Nutrition Randomized Controlled Trials Respiratory Function Tests CHILD
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Therapeutic efficacy and safety rating of Tui-Pushing chest-back manipulation for children with cough variant asthma Therapeutic efficacy and safety rating of Tui-Pushing chest-back manipulation for children with cough variant asthma 被引量:4
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作者 ZHU Binye LI Xue 《Journal of Acupuncture and Tuina Science》 CSCD 2022年第3期187-192,共6页
Objective:To observe and evaluate the clinical efficacy and safety of using pediatric Tuina(Chinese therapeutic massage),Tui-Pushing chest-back manipulation,in treating children with cough variant asthma(CVA).Methods:... Objective:To observe and evaluate the clinical efficacy and safety of using pediatric Tuina(Chinese therapeutic massage),Tui-Pushing chest-back manipulation,in treating children with cough variant asthma(CVA).Methods:Seventy-two kids with CVA were divided into two groups using the random number table method,with 36 cases in each group.The control group received the conventional Tuina treatment,and the observation group received additional Tui-Pushing chest-back manipulation.The clinical efficacy and adverse reactions were observed and recorded for the two groups.Results:After three treatment courses,compared with the control group,the observation group showed advantages in the total effective rate,reducing the number and intensity of cough and improving the nature of cough(P<0.05).However,at the one-month follow-up,there were no significant differences between the two groups in these parameters(P>0.05).Regarding the adverse reaction rate,there was no significant between-group difference(P>0.05).Conclusion:It is effective and safe to use pediatric Tuina,Tui-Pushing chest-back manipulation,plus the conventional treatment protocol to treat CVA in children. 展开更多
关键词 TUINA Massage Pediatric Tuina Tui-Pushing Manipulation Point Danzhong(CV17) Feishu(BL13) Cough Variant Asthma Child Preschool
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