Objective To observe the clinical efficacy of acupuncture plus medicine in treating laryngopharyngeal reflux due to liverqi stagnation and spleen deficiency.Methods A total of 70 patients were divided into a control g...Objective To observe the clinical efficacy of acupuncture plus medicine in treating laryngopharyngeal reflux due to liverqi stagnation and spleen deficiency.Methods A total of 70 patients were divided into a control group and an observation group by the random number table method,with 35 cases in each group.Both groups were treated with conventional medications,and the observation group was treated with additional acupuncture therapy.The reflux symptom index(RSI)and reflux finding score(RFS)were evaluated.Esophageal motility indicators such as lower esophageal sphincter pressure(LESP)and upper esophageal sphincter pressure(UESP),and salivary pepsin level were measured.The clinical efficacy was also compared.Results The total effective rate of the observation group was higher than that of the control group(P<0.05).After treatment,the RSI and RFS scores in both groups decreased significantly(all P<0.05),and the RSI and RFS scores in the observation group were significantly lower than those in the control group(both P<0.05).There were no significant changes in the LESP and UESP in the control group(both P>0.05),while LESP and UESP in the observation group increased significantly(both P<0.05),and higher than those in the control group(both P<0.05).The salivary pepsin levels in both groups decreased(both P<0.05),and the salivary pepsin level in the observation group was significantly lower than that in the control group(P<0.05).Conclusion Acupuncture plus medicine can improve symptoms and signs in patients with laryngopharyngeal reflux due to liver-qi stagnation and spleen deficiency,and regulate esophageal motility and salivary pepsin level.Its efficacy is more significant compared with medicine alone.展开更多
文摘Objective To observe the clinical efficacy of acupuncture plus medicine in treating laryngopharyngeal reflux due to liverqi stagnation and spleen deficiency.Methods A total of 70 patients were divided into a control group and an observation group by the random number table method,with 35 cases in each group.Both groups were treated with conventional medications,and the observation group was treated with additional acupuncture therapy.The reflux symptom index(RSI)and reflux finding score(RFS)were evaluated.Esophageal motility indicators such as lower esophageal sphincter pressure(LESP)and upper esophageal sphincter pressure(UESP),and salivary pepsin level were measured.The clinical efficacy was also compared.Results The total effective rate of the observation group was higher than that of the control group(P<0.05).After treatment,the RSI and RFS scores in both groups decreased significantly(all P<0.05),and the RSI and RFS scores in the observation group were significantly lower than those in the control group(both P<0.05).There were no significant changes in the LESP and UESP in the control group(both P>0.05),while LESP and UESP in the observation group increased significantly(both P<0.05),and higher than those in the control group(both P<0.05).The salivary pepsin levels in both groups decreased(both P<0.05),and the salivary pepsin level in the observation group was significantly lower than that in the control group(P<0.05).Conclusion Acupuncture plus medicine can improve symptoms and signs in patients with laryngopharyngeal reflux due to liver-qi stagnation and spleen deficiency,and regulate esophageal motility and salivary pepsin level.Its efficacy is more significant compared with medicine alone.