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伯胺N1923萃取铁的囊效应 被引量:9
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作者 李雪梅 杨永会 +3 位作者 邵华 孙思修 刘兆平 钟红梅 《高等学校化学学报》 SCIE EI CAS CSCD 北大核心 2001年第1期59-62,共4页
由研究伯胺 N1 92 3萃取铁 ( )的平衡 ,提出了萃取体系中“囊效应”的概念 ,并用红外光谱和电镜等分析方法加以佐证 .当萃取剂伯胺 N1 92 3的浓度达到一定值后 ,在有机相中形成了球状的胶囊 (或反向胶团 ) .其萃取过程中既有离子缔合萃... 由研究伯胺 N1 92 3萃取铁 ( )的平衡 ,提出了萃取体系中“囊效应”的概念 ,并用红外光谱和电镜等分析方法加以佐证 .当萃取剂伯胺 N1 92 3的浓度达到一定值后 ,在有机相中形成了球状的胶囊 (或反向胶团 ) .其萃取过程中既有离子缔合萃取 ,又有胶束增溶作用 ,大大提高了伯胺 N1 92 3萃取铁的分配比 ,呈现出“囊效应”特征 . 展开更多
关键词 囊效应 反向胶团 萃取 伯胺N1923
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Effect of Long-Term Rice Straw Return on Soil Glomalin, Carbon and Nitrogen 被引量:49
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作者 NIE Jun ZHOU Jian-Min +2 位作者 WANG Huo-Yan CHEN Xiao-Qin DU Chang-Wen 《Pedosphere》 SCIE CAS CSCD 2007年第3期295-302,共8页
A long-term experiment was conducted to investigate how long-term fertilization and rice straw incorporation into soil affect soil glomalin, C and N. The combined application of chemical fertilizer and straw resulted ... A long-term experiment was conducted to investigate how long-term fertilization and rice straw incorporation into soil affect soil glomalin, C and N. The combined application of chemical fertilizer and straw resulted in a significant increase in both soil easily extractable glomalin (EEG) and total glomalin (TG) concentrations, as compared with application of only chemical fertilizer or no fertilizer application. The EEG and TG concentrations of the NPKS (nitrogen, phosphorus, and potassium fertilizer application + rice straw return) plot were 4.68% and 5.67% higher than those of the CK (unfertilized control) plot, and 9.87% and 6.23% higher than those of the NPK (nitrogen, phosphorus, and potassium fertilizer applied annually) plot, respectively. Application of only chemical fertilizer did not cause a statistically significant change of soil glomalin compared with no fertilizer application. The changes of soil organic C (SOC) and total N (TN) contents demonstrated a similar trend to soil glomalin in these plots. The SOC and TN contents of NPKS plot were 15.01% and 9.18% higher than those of the CK plot, and 8.85% and 14.76% higher than those of the NPK plot, respectively. Rice straw return also enhanced the contents of microbial biomass C (MBC) and microbial biomass N (MBN) in the NPKS plot by 7.76% for MBC and 31.42% for MBN compared with the CK plot, and 12.66% for MBC and 15.07% for MBN compared with the NPK plots, respectively. Application of only chemical fertilizer, however, increased MBN concentration, but decreased MBC concentration in soil. 展开更多
关键词 C GLOMALIN long-term fertilizer experiment N rice straw return
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Combinatorial effects of NaomaiYihao Capsules(脑脉一号胶囊) and vascular endothelial growth factor gene-transfected bone marrow mesenchymal stem cells on angiogenesis in cerebral ischemic tis sues in rats 被引量:8
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作者 郭建文 陈朝 +1 位作者 黄燕 黎奔 《Journal of Traditional Chinese Medicine》 SCIE CAS CSCD 2012年第1期87-92,共6页
OBJECTIVE:To investigate the combinatorial effects of Naomai Yihao(NMYH) Capsules(脑脉一号胶囊) and vascular endothelial growth factor(VEGF) gene-transfected bone marrow mesenchymal stem cells(BMSCs) on angiogenesis i... OBJECTIVE:To investigate the combinatorial effects of Naomai Yihao(NMYH) Capsules(脑脉一号胶囊) and vascular endothelial growth factor(VEGF) gene-transfected bone marrow mesenchymal stem cells(BMSCs) on angiogenesis in cerebral ischemic tissues in rats and the mechanism.METHOD:BMSCs were isolated and cultured from bone marrow by an adherence method.Then,BMSCs were transfected with the eukaryotic expression plasmid pEGFP-VEGF 165 by positive ionic liposome transfection.A rat model of middle cerebral artery occlusion(MCAO) was established.Rats were allocated to six groups:model,BMSC,VEGF gene-transfected BMSC transplantation(BMSC/VEGF),NMYH,combined NMYH and BMSC/VEGF(combined treatment group) and sham operation groups.The behavioral rating score(BRS) of rat and the expression of CD34 and VEGF in brain tis sue were measured by immunohistochemistry on days 7,14 and 21 after reperfusion.Angiogenesi was observed and evaluated with laser scanning confocal microscopy.RESULTS:The BRS of rats in NMYH,BMSC transplan tation and combined treatment groups was significantly lower than that of the model group(P< 0.001),with no significant difference between NMYH and transplantation groups(P=0.619).The expression of CD34 andVEGF in NMYH,transplanta tion and combined treatment groups increased(P< 0.001),with a significant difference between NMYH and transplantation groups(P<0.001).The blood vessel area in NMYH,transplantation and com bined treatment groups was significantly increased(P<0.05),without a significant difference between NMYH and transplantation groups(P=0.873).CONCLUSIONS:VEGF gene-transfected BMSCs im prove angiogenesis in the cerebral ischemic area NMYH Capsules promote angiogenesis in MCAO rats treated with BMSC transplantation,which show an improved BRS.The mechanism of angio genesis may be related to up-regulation ofVEGF ex pression. 展开更多
关键词 Bone marrow mesenchymal stem cells naomai yihao capsule Vascular endothelial growth factor Eukaryotic expression plasmid Transplantation Cerebral ischemia ANGIOGENESIS
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Preparation and evaluation of doxorubicin-luminespib co-loaded multivesicular liposomes
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作者 Yajie Liu Yu Wang +2 位作者 Jiajia Li Xiaoqing Xu Xinru Li 《Journal of Chinese Pharmaceutical Sciences》 CAS CSCD 2021年第9期736-742,共7页
A combinational therapeutic system that simultaneously administrates various pathways is preferred for anti-cancer treatment.In the present study,we successfully constructed a co-delivery system,multivesicular liposom... A combinational therapeutic system that simultaneously administrates various pathways is preferred for anti-cancer treatment.In the present study,we successfully constructed a co-delivery system,multivesicular liposomes(MVLs)co-encapsulating doxorubicin(DOX)and luminespib(AUY922).A simple and accurate dual-wavelength spectrophotometric method was established for the determination of DOX and AUY922 in liposomal formulation.MVL-loading drugs were prepared by a multi-emulsion solvent evaporation method,which exhibited excellent physicochemical properties,such as particle size of 3–8μm and high entrapment efficiency above 95%for DOX and 73%for AUY922.The synergetic cytotoxic effect for these two drugs was evaluated in MDA-MB-231 cells.The in vitro antitumor studies demonstrated the superior anti-proliferation activity of DOX and AUY922 with a combination index of 0.43,indicating a great synergistic effect.The experimental data suggested that combinational use of DOX and AUY922 within liposomes could be an effective way to develop efficient treatments of cancers. 展开更多
关键词 DOXORUBICIN Luminespib Multivesicular liposomes Combination therapy Synergistic effect
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